2013 Abstracts

Arlene Johnston, Brigham Young University Nursing Description:

Laura Gilpin, Brigham Young University Nursing Purpose/Aims: The purpose of this pilot study was (1) to examine nursing students’ perceptions of their first experience with death in the clinical setting and (2) to determine if curricular changes are necessary to better prepare nursing students effectively cope with their first death experience as a nurse. Background: Death, particularly the unexpected death of a patient, is an emotionally charged, high-stress situation for any nurse. Nursing students encounter scenarios involving death and dying in simulation laboratories, as well as in the clinical setting. In simulation settings debriefing is routinely accomplished and is seen as a critical component of the learning experience. However, Leavy and colleagues (2011) found that even during formal simulation debriefing sessions nursing students were not able to fully process their emotions In real-life clinical settings, the stakes are even higher as nursing students must be able to effectively cope with the death of a patient. Unfortunately, research on students’ first experience with death is limited. Huang and colleagues (2010) found students may not receive adequate support from clinical nursing instructors during the dying process and after a patient’s death. Methods: This was a descriptive mixed methods pilot study. An online anonymous survey was sent to students in the Brigham Young University College of Nursing regarding their first experience with death in the clinical setting (N=306). Students were e-mailed a brief description of the research project and an invitation to participate in the study only if they had experienced the death of a patient. Completion of the online questionnaire implied consent. The participants answered 5 demographic questions and 11 survey questions with the estimated time commitment for each participant being 15 minutes. Results: The online questionnaire was sent to 306 BSN nursing students Approximately 10% initially responded (N=33). A smaller group (N=25) completed the entire survey. Qualitative comments from nursing students who experienced the death of their patient included feeling sad, shocked and uncomfortable. Fifty percent of the nursing students did not receive any debriefing from their clinical instructor following the event.

Derek Chang, University of Utah Bioengineering Atrial fibrillation (AF), the most common cardiac arrhythmia, is a rapid, irregular heart beat arising from uncontrolled and asynchronized electrical activation in the atria. This disruption of the normal electrical signaling hinders the contraction of the heart, leading to decreased blood flow, possible clot (thrombus) formation, and an increased risk of stroke. The left atrial appendage (LAA) is a small muscular pouch of highly variable anatomy within the left atrium. The LAA plays a prominent role in thrombus formation in patients with AF because of decreased blood flow within this structure. Thus, we hypothesized that the shape of the left atrial appendage is different in AF patients with a documented history of stroke. We used statistical shape analysis to determine which LAA shape variations contribute to stroke based on a cohort of AF patients who had both MRI and CT scans and a documented history of stroke. We manually delineated the boundaries of the LAA from each patient’s CT and MRI scans to analyze the resulting LAA segmentations for shape variations across imaging modalities and history of stroke. The results showed that patients who have AF and a history of stroke have an LAA with a narrower insertion site into the left atrium and are larger in size. In contrast, patients who have AF, but no history of stroke, have an LAA with a wider insertion site, which are smaller in size. By isolating specific LAA shape variants indicative of an underlying risk of stroke, we can use this shape classification scheme to better tailor AF therapies to each individual patient.

Kinsley Oates, Weber State University Interior Design Research shows that athletics help pave the wave for student to pay for college and obtain an education. (Proposition 48, N.C.A.A 2010) Proposition 48 supports this cause by focusing on the output of graduating students, rather than the input of entrance standards. The N.C.A.A studies show, “The persistence of low-achieving students in college have suggested that participation in athletics is frequently the catalyst for student who have not performed well in high school to study more diligently and, ultimately, to graduate.” Steve Kendall wrote that for many at-risk students, athletics is the only reason they go to school. He states, “These at-risk students who have no other reason to attend school other than athletics benefit from this policy. They are in classes and participating in the activities and exercises happening in the classrooms.” Jerry Tarkanian a coach at UNLV defends his stance on trying to help underprivileged players deserve a shot at straightening out their lives. The Maple Leaf Training Center located in Spanish Fork Utah, will provide at-risk student who attend high school a privilege to obtain scholarships and a chance of going to a college or university. Students who live in poverty and low income home do not have an option to get into colleges or universities. This 23,000 square foot facility will help 1st generations college students train and obtain scholarships, both academic and athletic for them to continue on to a college or university to pursue their future.

Sarah Breinholt, Weber State University Interior Design Spiriti Forti Rebuild and Recovery Center is a facility that heals the psychological and body issues for individuals with eating disorders. Research has shown that long-term stay care facilities should contain a “home-like” atmosphere that reflects the site’s surroundings. In a study by Schneider (2008) explains the importance for the patient to feel comfortable and relaxed in order to achieve maximum recovery. In addition, a study by Kaya (2009) explores the effect that color has on individual’s emotions and health. A study that was completed on a group of individuals of all ages and all nationalities shows that overall; people have very similar reactions to the same colors in spite of age or race. The colors blue and green have been recognized to reduce anxiety and promote calmness and well-being. Because of this reason, this color palette will be implemented in the design of this recovery center. A former historic train station in St. George, Utah has been acquired by Spiriti Forti Rebuild and Recovery Center to be renovated to accommodate a getaway for patients to escape the world and rebuild their body image and self-esteem. Among the features of the care center will cafeteria/kitchen that focuses on education and nutrition, rooms for long-term stay, as well as spaces for multiple activities for individual and group building exercises. This facility should become a place that provides all the necessary components for patients to make a full recovery of their psychological and image disorders.

Thomas Skousen, Dixie State University Art Concordia apostolorum, the union of apostles, is found in literature, art, and even the topography of Rome. Rome is unique in the fact that it unites Peter and Paul. Early Christians revered these saints and dedicated two of the most important churches in the city to them. Their deaths in Rome were a crucial factor in identifying Rome as the principal capital of Christendom. As Christianity spread and was accepted throughout the empire, different Christian centers arose, aside from Jerusalem and Rome. In order to maintain its place at the top tier of the Christian hierarchy, the Roman Popes used the idea of concordia apostolorum to not only speak to Roman citizens, but also to pilgrims who visited the city. The use of concordia apostolorum extended into the ninth century with Pope Paschal I’s (817-824) mosaics at Santa Prassede. These have historically been categorized into the Carolingian Renaissance. However, Paschal and earlier popes were trying to create a uniquely Roman Renaissance, and Peter and Paul’s place in art is crucial to their propaganda. The apse mosaic in Santa Prassede employs concordia apostolorum to promote the primacy of Rome. Louis the Pious inherited the empire from his father Charlemagne and surrounded himself with bishops and scholars who questioned the authority of the pope, thus igniting a struggle between the pope and the Carolingians. This paper will show that Paschal I commissioned art that emphasized his role in carrying out the ministerial work of Peter and Paul. In art and in life, Paschal sought to become not only the principal figure in Christianity, a living apostle, but also a chief player in Europe’s political structure.

Hilary Wolfley, Brigham Young University Dance The purpose of this project is to enhance the caliber and reputation of ballet in higher education-specifically contemporary ballet at BYU-while strengthening my own choreographic abilities under the guidance and coaching of my mentor, Shani Robison, Associate Professor. I have choreographed an original contemporary ballet entitled “Transition” that explores the ways in which we react to the challenges of change in our lives. Through exploring this theme, creating innovative movement, and rehearsing with talented dancers, I am working closely with my mentor to fulfill UCUR’s mission to creatively contribute to the discipline of contemporary ballet. I recently completed this project as the culmination of my undergraduate work at BYU as a dance major. This is the link to my project as performed last week at the BYU Ballet Showcase: http://youtu.be/j1t0MPcLUyw (DVD available upon request). The BYU Ballet Program has selected me as the only ballet student from BYU this year to represent undergraduate student creative work by presenting my project at the American College Dance Festival Northwest Region at Southern Utah University March 11-15, 2013 (ACDF). During this festival, my piece will be viewed by collegiate dance students and educators from across the country and adjudicated by internationally renowned experts in the dance field.

Israel Worthington, Utah Valley University Science and Health The Nation and world’s dependency on fuels has steadily grown over the last several decades. The world’s consumption of oil dramatically increases in the United States and peaks at approximately 20 million barrels of oil each day. Predictions of decreasing fuel reserves and increasing costs have made the development of a renewable fuel source increasingly appropriate. Much research has been done using the fermentative process to produce biofuels as an alternative fuel source, but the research attempting to utilize photosynthetic bacteria as a producer of alternative fuels is relatively undeveloped. In this research, it was attempted to transform cyanobacteria with the gene necessary to produce the enzyme methyl-butenol synthase, which catalyzes the production of the biofuel methyl-butenol. The gene for methyl-butenol was successfully transformed into cyanobacteria on a plasmid, and production of the enzyme methyl-butenol synthase was successfully detected via western blotting. The production of an alternative fuel source using photosynthetic bacteria could create a cheap, renewable, and more environmentally friendly source of fuel.

Deborah Nelson, University of Utah Pediatrics Families of pediatric cancer patients are presented with significant emotional, social, and financial challenges. Most children with cancer are treated in pediatric oncology centers located in urban areas and many must travel great distances for therapy. This study aims to evaluate the burden of care associated with pediatric cancer care and to determine the impact of the location of patients’ residence on those burdens. We administered a n=310 (48-item, English) and n=46 (72-item, Spanish) survey to the primary caregiver of patients, ages 0-18 years, diagnosed with a cancer between three to six months prior to the survey. Survey domains included measures of rurality, time from first symptoms to diagnosis, financial burden (travel costs and time, missed work, relocation) and missed school. Survey analysis suggests rural families and those traveling >2 hours to a pediatric oncology center took longer to obtain diagnosis, missed more work days, paid more in travel expenses and relocated more often than families living closer. Of the respondents, 18% were considered “rural” with 38% reporting greater than one-hour travel time and 25% reporting greater than two-hour travel time. Mean onset of initial symptoms to diagnosis was 11.4 weeks for rural and 7.6 weeks for urban patients. Mean out of pocket costs per clinic visit for rural were over three times that of urban patients. Twenty-nine percent (n=102) moved since diagnosis; of that 33% reported moving was directly due to cancer. Fifty-six percent of school-aged patients discontinued school; of those 28% were unable to “keep up” and 10% repeated a grade. Caring for a child with cancer places a significant number of burdens on the patient’s family. This burden appears greater for patients living in rural and distant areas and could effect patient care and access to treatment.

Samantha Webber, Brigham Young University Nursing Background: In November of 2012, a small group from BYU’s College of Nursing returned to Guayaquil, Ecuador to measure anemia indicators post interventions in school age children. In May of 2012 a larger group, including students, from BYU’s College of Nursing had visited Guayaquil for the fourth consecutive year to assess malnutrition and anemia rates in school age children. This multi-phase research project which began in May of 2009 found that nearly 41% of the children in this area suffered from anemia (below 11g/dl as per WHO guidelines). The adverse effects of anemia for these children can include: weakness, fatigue, shortness of breath, and poor concentration. Anemia may result from deficiencies of iron, B12, folic acid, and may also be the result of intestinal parasites. A nutrition survey conducted among these same school children showed that daily intake of iron, B12, and folic acid were below recommended levels. Intervention: In May of 2009 Hogar de Cristo (HDC), a non-profit organization, began distributing 6 to 8 ounce bottles of soy milk as a school snack for each school-aged child at a few of the schools in the area. A local pharmaceutical company who supplied vitamin and iron supplements during the first year of the soy milk distribution, reassessed anemia rates in those children in November of 2009. The BYU College of Nursing continued to assess school- aged children for measures of anemia and growth and development in 2010 and 2011 as directed by Hogar de Cristo. After 2011 it was difficult to correlate anemia and soy milk because of changes in the sample from year to year. In May of 2012 the BYU College of Nursing shifted their focus to four interventions with the aim of determining which one would best lower anemia rates. The study focused on students at four schools in the perimetral area, each school received one of the interventions as an adjunct to soy milk: vitamin supplements, antiparasites, vitamins and antiparasites, and a control group (soy milk only). Growth and development measures along with rates of anemia were reassessed in November 2012. Results: In May of 2012 the BYU College of Nursing tested 1041 school-ages children for growth and development and anemia. growth and development rate results spanning the four years of testing, and a comparison of anemia rates between intervention groups and control groups.

Ashlee Manwaring, Brigham Young University Nursing Purpose: To examine how the new policy of Medicare/Medicaid reimbursement being based on HCAHPS scores affects nursing care. Rationale: The Patient Protection and Affordable Care Act (PPACA) mandates that Medicare and Medicaid reimbursement be based on hospital performance and patient satisfaction. Patient satisfaction is measured nationally through the Hospital Consumer Assessment of Healthcare Providers and Systems (HCAHPS) survey. The HCAHPS survey was development in the early 2000’s to create a uniform measure for patient perspectives regarding their inpatient stay; however, with the HCAHPS scores being related to Medicare and Medicaid reimbursement, hospitals are required to reevaluate their quality of care from the patient, not medical, perspective. Van Empel et al. (2011) found that physicians and nurses primarily value medical outcomes of treatment. While, at the same time, patient’s value patient-centeredness, even if it means decreasing the desired outcome of treatment. Undertaking: A literature review was completed by searching in CINAHL and Medline. Preliminary research used HCAHPS and Medicare reimbursement as key words. Second, a search was completed using HCAHPS and nursing as key words. All results were published between 2008 and 2012. Outcomes: Kutney-Lee et al. (2009) reported that patient satisfaction was primarily linked with nurse-to-patient ratio, interdisciplinary collaboration and work environment. Research by Robinson and Watters (2010) found the main factor in patient dissatisfaction was feeling like the nurses were short staffed, task-oriented and rushed, leaving the patient lacking adequately communication to understand their situation. Van Empel et al. (2011) reported patients’ willingness to change providers and facilities to received patient-centered care. Conclusion: Nurses have the greatest potential to effect patient satisfaction. Therefore, with the new regulation of Medicare and Medicaid reimbursement based on patient satisfaction surveys, nurses have a greater responsibility to ensure patient satisfaction. From the research presented, the main nursing implication is to help each patient feel like their care is centered on what is important to that individual. This can most easily be accomplished by the nurse opening a line of communication with the patient, and then advocating for the patient’s wishes.

Xin Wan, University of Utah College of Health, and Department of Endocrinology, Metabolism, and Diabetes We hypothesized that PP2A activation is required for lipid-induced, ceramide-mediated arterial dysfunction. Mice haploinsufficient for dihydroceramide desaturase (des1+/-) and their wild-type littermates (des1+/+) were infused (iv) for 6 h with lard-oil (LO) or vehicle (veh). Subgroups of LO and veh mice were treated (1.5 mg/kg IP) for 3 days prior to infusion with the PP2A inhibitor LB1 (Lixte Biotechnology, NY). LO increased ceramide accrual in arteries from des1+/+ but not des1+/mice. Palmitate (3 h x 500 uM) increased (p<0.05) PP2A activity, and impaired (p<0.05) insulin-stimulated p-eNOS(S) 1177 to eNOS in endothelial cells, and these responses were negated by LB1 (4 uM; n=5-8). Endothelium-dependent and -independent relaxation of femoral arteries (~ 150 um i.d.) was assessed using acetylcholine (ACh) and sodium nitroprusside (SNP), respectively (n=3 mice / group, 3 vessels / mouse). ACh-mediated (2×10-8, 3×10-8, and 6×10-8 M) relaxation (%) was less (p<0.05) in LO des1+/+ (30±2, 41±3, and 61±4, respectively) vs. veh des1+/+ mice (48±4, 67±6, and 73±6, respectively). Endothelial dysfunction observed in LO des1+/+ mice was less severe when ceramide accrual (i.e. LO des1+/mice) or PP2A activation (i.e., LB1 +LO des1+/+ mice) were prevented. SNP-evoked vasorelaxation was intact among groups. LO-induced ceramide accumulation induces endothelial dysfunction that is dependent upon PP2A activation. ADA1-12-BS-208, 2R15HL091493

Edie Kieu-Mi Nguyen and Cassandra Nguyen, University of Utah Nursing Home hospice care is a growing area within the health care system. However, because of the difficulty in gaining access to these patients and caregivers in the home, research findings have been slow to keep pace with this growth. While hospice has been at the forefront of family-centered care, explicitly stating that the unit of care is the family, there has been little empirical research to show who is actually involved in this care in the home on a regular basis. Hypothesis: Our goal of this project was to describe who is present at the nurse home visit with the patient. Research Method: This research, part of a larger intervention study, involved reviewing audio recordings of home hospice visits to set up a coding system for future communication coding. During this review, we also identified and documented those present during the visit. Results: In our sample of 115 home hospice visits, 12 nurses caring for 13 patients spent an average of XXX minutes each (SD=XXX) in the home. We have found that caregivers are present 80% of the time. Our data shows that a spouse is present in 28% of visits. In 58.3% of visits, a daughter is present, while sons are present in only 3.1% of visits. Implications: It is important to know who is present at the visit and how long they spent with the patient to increase our understanding of what goes on in home hospice care. This research has implications for improving patient care. For example, in order to promote a more family orientated home care; more family members should participate in nurse visits. This descriptive research can be used in practice for hospices to know who to expect during patient home visits, as well as to incorporate the family members better into the patient care plan.

Elizabeth Johnson, University of Utah College of Health, and Division of Endocrinology, Metabolism, and Diabetes Constant-flow left ventricular assist devices (LVAD) are implanted in heart failure patients to assist the heart in pumping blood through the body either temporarily as a “bridge” mechanism until a heart transplant or permanently as a destination therapy. The blood flows constantly with an LVAD contrary to the natural pulsatile flow of the human heart. We wanted to determine if this constant flow attenuated the function of the arteries. A transmural biopsy was taken from seven male patients (52±6 years old) when the LVAD was implanted (pre) and again 142±2 days later upon LVAD explant (post). Arteries were obtained from the pre and post tissue biopsies. Vessel function was assessed using isometric tension techniques. After Lmax tension was determined for each vessel, the contraction-response curve of each vessel was tested using potassium chloride (KCl, 10-100 mM). Next the vessels were pre-contracted to ~65% maximal tension and treated with bradykinin (BK, 10-6 to 10-10 M) and sodium nitroprusside (SNP, 10-4 to 10-9 M) to determine, respectively, endothelium-dependent and -independent vasorelaxation. Maximal KCl-evoked contraction (0.99±0.22 and 0.69±0.14 mg tension development / μm vessel length), maximal BK-evoked vasorelaxation (64±13% and 80±7%), and maximal SNP-evoked vasorelaxation (92±3% and 92±4%), was similar in arteries obtained from pre (n=13 arteries, 206±40 μm i.d.) and post (n=14 arteries, 288±24 μm i.d.) transmural biopsy samples, respectively. These preliminary data indicate that coronary vascular function is not attenuated by LVAD implantation.

Rodolfo Rafael, Weber State University Performing Arts In preparation for choreographic projects for my degree, I attended the world-class Ririe-Woodbury Dance Company workshop on an undergraduate grant. The workshop included various subjects, but the most valuable and challenging approach was the emphasis on the “frame” of a work of art and how by changing the frame, the meaning and impact of art is affected. I became interested in the artistic and societal frame of marriage, and decided to use this frame for my student choreographic project. Since it was in an academic setting, I presented the idea in an open-ended manner, one that allowed the students to express their concerns. I was intent not so much on the outcome of the piece, but that the subject of marriage be questioned. I started by having a discussion with the students. I solicited and noted their boundaries. After finding an agreed upon point of compromise on how to approach this issue, we decided to move forward. Unfortunately, some never came back. In fear of losing more students, I changed directions. This experience brought me to a new issue. How much academic freedom do students have? Is higher education supposed to provide a platform where students are free to explore open inquiries? What if others aren’t willing to deal with social issues? Should students change the subject matter of their research to avoid offending others? How do we encourage others to discuss issues they don’t agree on? Is there a way we can find common ground and share the frame?

Brittany Brown, Weber State University Interior Design According to the article Contributions of Built Environment 68% of the adult population is considered obese. (Rahman, 2011) The article also states that childhood obesity is on a steady rise. The research provides evidence that obesity shortens Americans life expectancy by 2 to 5 years on average. The study by Rahman recommends that adults engage in at least 150 minutes of moderate-intensity aerobic activity weekly and at least 60 minutes every day. The Spencer Weight Loss Retreat is a 18,000 square foot facility located in Meridian, Mississippi. The weight loss retreat will provide weight loss training and medical attention for those residents of Meridian who are considered obese and want treatment to gain back their lives. The weight loss center will provide each patient with a personal trainer who will guide in their weight loss. The facility will provide the patients access to their gym where they can use treadmills, bikes, weights, outdoor routines, and other activities to meet the 150 minute workouts a week. The Spencer Weight Loss Retreat will provide a classroom to educate the patients in nutrition and other life skills.

Darien Shapiro, University of Utah Pharmacology and Toxicology Exposure to wood smoke particulate matter (WSPM) has been linked to exacerbation of asthma, development of chronic obstructive pulmonary disease (COPD), and premature death. Combustion-derived PM (cdPM) such as cigarette smoke (CS), diesel exhaust (DEP), and WSPM, activate transient receptor potential ankyrin-1 (TRPA1) which promotes neurogenic inflammation/edema and airway irritation/cough. The mechanism of TRPA1 activation by DEP and CS involves the electrophilic/oxidant binding (3CK) and menthol-binding (ST) sites, and a novel mechanosensitive site. We hypothesized that WSPM would activate TRPA1 through one or more of these sites similar to other cdPM. Pine and mesquite PM were generated in the laboratory. Both types of WSPM particles activated TRPA1 in human TRPA1 over-expressing HEK-293 and primary mouse trigeminal (TG) neurons. WSPM also activated TRPA1 in A549 cells, a human alveolar adenocarcinoma cell line, which has recently been shown to express TRPA1. HC030031, a TRPA1 specific antagonist, attenuated the calcium flux due to WSPM treatment in both human A459 cells and mouse primary TG neurons. Differential activation of TRPA1, as a function of particle size, demonstrated that PM2.5 m were most potent. Several known chemical components of WSPM, including 3,5-ditert-butylphenol and agathic acid were TRPA1 agonists. Both WSPM and agathic acid activated TRPA1 primarily via binding the 3CK site, based on inhibition of calcium flux by glutathione and mutation of the 3CK site. Conversely, 3,5-ditert-butylphenol activated TRPA1 through the ST site. This study established the mechanism by which WSPM and associated chemical components activated TRPA1 which may help tailor effective therapeutic treatments for WSPM pneumotoxicity. Support: NIEHS ES017431 and the University of Utah Undergraduate Research Opportunities Program.

Carolina Silva, Jasmin Alves, Katrina England, Courtney Hammond, and Ethel Tackle-Yarbol; Westminster College Psychology Bullying among adolescents is a common problem that deserves attention. Youth City, a multi-site after school youth program in the Salt Lake City area catering to youths ages 8-13, expressed an interest in learning more about bullying experiences in their attendees with the aim of developing a program for intervention and prevention. We partnered with Youth City to develop the current project, the goals of which were twofold: (1) to measure the prevalence and types of bullying experienced by 53 youths attending one Youth City site (our participants) and, (2) to work with the youth and the site coordinator to develop a bullying intervention and prevention program. Participants completed a modified version of the Olweus Bully Victim Questionnaire, in which 31 behaviors of bullying were assessed. Behaviors included examples of physical bullying, relational bullying, cyber bullying, and bullying due to one’s ethnicity or sexuality. Participants were asked to report whether each behavior had ever been done to them (victim role), done by them to another (bully role), or witnessed by them in the role of bystander. Results showed that the participants had experienced many of the behaviors as either victims, bullies, or bystanders. The second step was to conduct focus groups in which participants were asked more about their bullying experiences and what they felt could be done to more effectively intervene and prevent bullying. Transcripts from the focus groups were analyzed for emergent themes. These themes, combined with input from staff and information gleaned from research into other programs, were used to draft a bullying intervention and prevention plan to be implemented at one Youth City site in the coming school year.

Trevor Hicks-Collins, Weber State University Psychology Austistic Spectrum Disorder (ASD) is an increasingly prevalent disorder, with approximately 1 of every 88 children in the United States diagnosed with the disorder. Several factors can exacerbate autistic symptoms in ASD children, including environment, diet, and sleep. Sleep problems in children with ASD’s occur more frequently than in non-ASD children, and their effects could be even more detrimental. The sleep literature in non-ASD children is clear about how sleep deficits adversely affect behavior and cognition, but there is little research to indicate the effects of sleep deficits on ASD children. This study was designed to assess the effect of sleep quality and quantity on ASD symptoms. The participants were children, ages 5-8, who were rated on the autistic spectrum. The children’s sleep was assessed using Actigraph monitors, which provided an objective measure of sleep quality and quantity. The children wore the monitors each night for one week. Also, parents and teachers kept daily records of the children’s sleep quantity and autistic behaviors, reporting both good and bad behaviors. A MANOVA was used to assess the effect of REM sleep, duration of sleep, and number of interruptions on autistic symptoms reported by parents and teachers. Results indicate that the amount and quality of REM sleep (both short-term and long-term) affects the frequency of autistic symptomology in children. In addition, results demonstrate that parents’ perceptions of sleep duration in their children is greatly distorted. Parents believe that their children are getting much more sleep than they actually are. Helping parents and teachers understand how important sleep is in affecting autistic symptomology can help modify behaviors. Studies like this are instrumental to providing us with information to better understand one of the fastest growing disorders affecting children today.

Alysha Waters, Utah State University Psychology Emotional distracters impair cognitive function. Emotional processing is dysregulated in affective disorders such as depression, phobias, schizophrenia, and post-traumatic stress disorder. Among the processes impaired by emotional distracters, and whose dysregulation is documented in affective disorders, is the ability to time in the seconds-to-minutes range, i.e., interval timing. Presentation of task-irrelevant distracters during a timing task results in a delay in responding suggesting a failure to maintain subjective time in working memory, possibly due to attentional and working memory resources being diverted away from timing, as proposed by the Relative Time-Sharing (RTS) model. We investigated the role of the prelimbic cortex (PrL) in the detrimental effect of anxiety-inducing task-irrelevant distracters on the cognitive ability to keep track of time, using local infusions of selective serotonin reuptake inhibitor fluoxetine (FLX). Given that some anti-depressants have beneficial effects on attention and working memory, e.g., decreasing emotional response to negative events, we hypothesized that FLX would improve maintenance of information in working memory in trials with distracters, resulting in a decrease of the disruptive effect of emotional events on the timekeeping abilities. Our results revealed a dissociation of the effects of FLX infusion in PrL between interval timing and resource allocation, and between neutral and anxiety-inducing distraction. FLX was effective only during trials with distracters, but not during trials without distracters. FLX reduced the detrimental effect of the distracters only when the distracters were anxiety-inducing, but not when they were neutral. Results are discussed in relation to the brain circuits involved in RTS of resources, and the pharmacological management of affective disorders.

Stephanie Lawanto, Utah State University Psychology Mice are excellent models for studying social behavior. Anomalies in the perception and processing of social cues may induce abnormal social approach or sexual behaviors. We performed an assessment of social behavior in NrCAM knockout female mice and wild-type littermates. We found that NrCAM knockout mice exhibit social behavioral deficits (reduced interaction with unknown conspecifics). Analysis of neuronal activation in a circuit relevant to processing and response to olfactory cues (olfactory bulb, amygdala, bed nucleus of the stria terminalis, hypothalamus), using cFos immunostaining, revealed differences in neuronal activation between NrCAM knockout mice and wild type littermates exposed to unknown conspecifics. These differences may be the result of anomalies in neuronal connectivity in the olfactory systems in NrCAM knockouts. These studies have the potential to generate a new understanding of pathophysiological mechanisms responsible for abnormal social behaviors, and to identify new treatment strategies to reduce social deficits in autism spectrum disease patients.

Jennifer Campbell, Utah State University Psychology Eating disorders are pervasive mental illnesses that overwhelm the lives of individuals who struggle with them. For individuals with anorexia nervosa or bulimia nervosa who do not respond to other treatments, Acceptance and Commitment Therapy has the potential to be effective. This presentation looks to orient researchers to Acceptance and Commitment Therapy while supplying a potentially useful treatment option for those who struggle with clinical anorexia nervosa or bulimia nervosa. The current literature comes together to support the effectiveness of Acceptance and Commitment Therapy for the treatment of eating disorders, specifically anorexia. This presentation focuses on the symptomatology and physical effects of anorexia and bulimia, as well as core principles and processes of Acceptance and Commitment Therapy. Future directions regarding the effectiveness of Acceptance and Commitment Therapy can be broadened to include adolescents as well as other types of eating disorders, such as binge eating disorder and eating disorders not otherwise specified.

Jordan Roberts, University of Utah Political Science I explore the tragic collision between individual self-determination and collective self-determination. While the conflict between these two ideals exists in many forms throughout political life, I focus on an international manifestation of this collision: the conflict between national sovereignty (predicated on collective self-determination) and international human rights (predicated on individual self-determination). There are perhaps no two international values more acclaimed, and no two values that clash as intensely; to allow for sovereignty means to allow for human rights abuses and to intervene in the name of human rights means to deny sovereignty. Eschewing traditional political lenses, I employ a tragic framework that 1) allows fuller engagement with the conflict and 2) avoids the pitfalls of the traditional lenses, including one-sidedness (which fuels the continuation of the conflict) and detachment (which allows for inaction). I draw on Sophocles’ Antigone, interpreting the title character as an embodiment of individual self-determination and Creon as an embodiment of collective self-determination. Furthermore, I argue that prominent attempts at finding a compromise between the two forces caught in this tragic collision, exemplified by the emerging international norm of Responsibility to Protect (R2P), are blind to the collision’s inherently tragic nature, and thus subvert one or both of the values at stake. I also address how this tragic blindness of notable theorists working on questions concerning human rights and sovereignty reproduces the blindness of another Sophoclean character: Oedipus. While tragic conflicts do not lend themselves to neat and tidy outcomes, a tragic framework embraces the conflict, instead of sidestepping it, and works towards an ambiguous, unhappy solution.

Jordin Kirkham, Snow College Psychology The purpose of this study is to observe, and analyze how average college students perceive professors in the media and if these perceptions have an effect on our own personal behaviors in the setting of a classroom, the influence of grades, and other factors. Based upon the review of literature, we have discovered that many of the studies regarding professors in the media have barley skimmed the surface, not providing much detail. We plan on going into more depth in our personal observation-analysis studies, seeing how we mainly perceive professors in movies, television, books, newspapers, etc. Results will be discussed.

Trenton Simmons, Brigham Young University Psychology Endogenous opioids are believed to modulate social sensitivity and aggression. The mu-opioid receptor gene in rhesus macaques has two common variants thought to be orthologous to human variants: C77G (CG) and C77C (CC). Based on previous studies, we predicted that rhesus macaques with the CG variant would exhibit higher rates of antisocial and aggressive behavior during social challenge. To test this hypothesis, we subjected mother-reared (MR) and nursery-reared (NR) subjects to an intruder challenge. 130 subjects were genotyped for the mu-opioid receptor gene variant. Behaviors were recorded after an unfamiliar intruder of the same sex and age was placed adjacent to the subjects’ home cage. CG, MR males received more non-contact aggression from group members than any other condition (p range<0.012), instigated more contact aggression than any other condition (p range<0.018), and received more contact aggression from the intruder than all other conditions except CC, NR males. In contrast to high rates of aggression, male, CG, MR subjects exhibited the lowest time in social affiliation when compared to all other genotype, sex or rearing conditions (p<0.026) except for CG, NR females. Our findings suggest that the mu-opioid receptor gene modulates aggression and antisocial behavior but only in the context of rearing and sex. These findings suggest one potential pathway for antisocial aggressive behavior development in men.

Brian Redford, Brigham Young University Psychology Small group treatment is a well-recognized as an effective intervention for persons diagnosed with schizophrenia. The most frequently used and efficacious types of small group treatment include psychoeducational, multifamily and skills groups. These groups are second only to psychopharmacology and frequency of use (Burlingame, Strauss & Joyce, 2013). Using the following search terms (group psychotherapy OR group counseling OR group treatment AND schizophrenia from 1990-2000) 62 studies were identified that used the aforementioned small group treatments. Of these, 29 were excluded based on strict inclusion criteria (i.e., sample size, study design, statistical methodology). 26 studies produced active group comparisons with controls, 3 studies produced single group pre-post comparisons and 5 studies produced waiting list control comparisons studying 2,248 patients. We conducted a meta-analysis using several descriptive (e.g. setting, ethnicity) and moderator (e.g. age of onset, group type) variables examining outcomes on key dimensions (e.g. relapse, hospitalization, medication adherence). Effect sizes estimated treatment effects (pre to post) and if these effects were maintained (post to follow up). Findings are examined in reference to treatment recommendations, feasibility of implementation and evidence based recommendations with respect to illness, protective, mechanisms of action and risk factors.

Sean Groathouse, Westminster College Mathematics Strategies for the Colonel Blotto game common in human play are generalized and compared through computer simulation. Furthermore, a variation on the game where the opponent’s resources are unknown is introduced, and differences between the variation and the classic game are explored with simulations on the common human strategies. Another variation on the scoring of the game is introduced and analyzed through simulations and a partial solution to the Nash equilibria in the two-front case.

Alexandra Pasi, Brigham Young University Mathematics Significant research in Machine Learning has been directed at the application and implementation of kernel-based learning methods. However, few studies have focused on the problem of kernel construction. This paper introduces a novel method for generating new kernels by solving differential equations for kernel functions. We examine specific kernels generated using this method. These kernels are applied to various data sets and compared against state-of-the-art kernels.

Justin Nybo, Weber State University Chemistry Finding a source of energy to supply the demands of energy consumption globally is one of the biggest problems facing society today. With fuel for transportation, heating, and manufacturing representing 70% of energy demands, an efficient fuel source must be used to supply the world’s energy needs (Gouveia and Oliveira, 2009). Algae represent an abundant source of biomass that could be used as a source to make biodiesel. Over the past several years, microalgae have become a logical potential candidate for producing biofuel in large masses. This is mainly due to the fact that they are more efficient at photosynthetic processes than traditional crops grown on the land (Vasudevan, 2008). Another feature of algae that make it suitable as a source for biodiesel is the fact that it can survive in harsh environments, such as salty water or compromised water where crops would not be able to grow (Mata et al., 2010). For my project, I researched and tested the effect of varying light frequency and intensity on the lipid production of Chlorella vulgaris algae. I along with Dr. Herzog and Abram Bernard, set up an array involving 40 flasks that were split into 8 rows and 5 columns. Each row had a unique frequency of light that came from a combination of red, green or blue LEDs. Each column varied the light intensity by changing the distance of the flask from the light source. The goal of our research was to show that algae of the species Chlorella vulgaris could be grown in this system and that algae growth rates were dependent on light frequency and intensity. This was accomplished by converting the lipids produced by the algae into fatty acid methyl esters (FAME) and then analyzing the FAMEs using a gas chromatograph (GC). In order for this analysis to be effective in terms of accuracy and precision, a quantitative method was developed and verified to quantify the lipid production of the algae under different light conditions. The light intensity and the number of photons of light emitted in each column were monitored by Chandler Greenwell, a fellow Chemistry student. The correlation between light intensity and the quantity of algae was noted during this project.

Abram Bernard, Weber State University Chemistry Alternative energy sources are becoming more important in today’s society. Algae provide a potential source of fuel that can is currently under study by many in the scientific community. The fats that algae can produce can be used as biofuel. Algae is a good candidate as a biofuel source because it can be grown in many conditions that crops, such as corn, cannot. Certain algae have very high percentages of fat that can be used for biofuel and it can be grown in large quantities. To add to the knowledge of algae and its potential as a fuel source, we have researched the effects of varying light conditions on the algae’s fat production. Working with faculty in the chemistry and microbiology departments at Weber State University, we set up an experiment to discover the effects of different wavelengths of light on fat production in algae. 40 samples of Chlorella Vulgaris were grown in different light environments. Our apparatus separated the algae into 8 different colored lights at 5 different. The intensity of light was quantified to allow us to map the changes. We extracted the fat from these samples using a transesterification method previously used on meat and analyzed them using a gas chromatography method we developed. Currently we are analyzing the correlations between the quantified light data, the mass of algae grown, and the amount of fats present in these samples. We hope to be able to draw conclusions from this data about the effects of varying light wavelengths and intensities on the fat production of algae. From these conclusions, we would be able to contribute to the research of algae as a source of biofuel. We have also approached this project as a way of developing interdisciplinary research here at Weber State University. Our work has not only provided us with data on this project but has also been involved in developing methods for future research by other undergraduates.

Jeremy Redd, Utah Valley University Physics Future space propulsion systems will likely use annihilation of matter and antimatter in propulsion system. Annihilation of matter and antimatter is not only the energy source of ultimate density 9×10^16 J/kg but also allows to utilize ultimate exhaust speed the speed of light c thus potentially allows to accelerate a payload to ultrarelativistic velocities. Such velocities make interstellar and even intergalactic travel possible in the lifetime of one generation only (20-30 years). In our presentation we discuss advantages and disadvantages of interstellar travel with relativistic and ultra-relativistic velocities. Using relativistic Tsiolkovsky rocket equation we also discuss the feasibility of achieving relativistic velocities with annihilation powered photon engine and technical challenges to build such engine.

David Pease, Utah Valley University Physics Transition regions to higher resonant modes of a bottle-shaped thermoacoustic prime mover (neck: 5.39 cm long, 1.91 cm ID; variable cavity with a sliding piston: up to 38 cm long, 4.76 ID) were studied. As the piston is extended, lengthening the cavity, starting from the neck, a transition of the dominant frequency from the fundamental to the first overtone occurs. However, when the length is then shortened, transition back to the first mode does occur at the same piston position, revealing hysteresis. Within the window of hysteresis for the cavity length, either state of the fundamental or first overtone is possible. Transition regions to higher modes continue as the length of the cavity is increased. The position and width of the hysteresis was studied for the first two transition regions as a function of input power and stack volume filling factor. Input powers studied were between 12.0 and 16.5 W and volume filling factors for the stack were about 3.0, 3.7 and 4.9%. The transition regions occurred with cavity lengths between 12.6 and 14.0 cm for the first transition and between 25.0 and 27.8 cm for the second transition. Preliminary results indicate that the transition region occurs shallower in the cavity and the hysteresis widens as the input power is increased. The hysteresis is wider for the second transition region. Decreasing the stack mass causes an increase of the hysteresis width, but has no strong effect on the hysteresis depth.

Joseph Roring, Utah Valley University Physics Removal of all cancerous tissue in breast conservation surgery (BCS) is critical to prevent local recurrence. Unfortunately, 30-50% of patients require additional surgery due to failure to resect all the necessary tissue. A real-time method for detecting infected tissue is therefore desirable. Previous studies have shown that the complexity of high-frequency (50 MHz) ultrasonic spectra can be correlated to a range of breast pathologies in BCS. However, the mechanism behind this correlation is still not very well understood. The purpose of this research is to explore the connection between tissue micro-heterogeneity and ultrasonic spectral complexity using breast tissue phantoms, i.e. materials that mimic breast tissue properties and microstructure. A physical basis can then be determined that links ultrasonic measurements to breast tissue pathology. Phantoms were made from a Knox® gelatin base and soluble fiber (Metamucil®). Heterogeneities simulating lobular and ductal components of mammary glands were created through the addition of polyethylene microspheres and nylon fibers. Pitch-catch and pulse-echo waveforms were acquired from the samples using high-frequency ultrasound. The data were analyzed by measuring the number of peaks (the peak density) in the first-order spectrum (Fourier transform of the time-domain waveform) and the slope of the second-order spectrum (two consecutive Fourier transforms of the time-domain waveform). The phantom specimens displayed first-order peak densities that were significantly greater and second-order spectral slopes that were significantly lower than homogeneous control samples. Phantoms with large fibers (250 micrometer diameter) showed the highest peak densities with values greater than 3x those of the controls. The peak density trend of the phantom samples with increased microscopic heterogeneity was consistent with data of breast tissue specimens. These results provide a physical mechanism for the use of these parameters in the imaging of breast tissues with atypical and malignant pathologies.

Sally Hansen, Utah Valley University Chemistry Cytochrome c oxidase (CcO) or complex IV is the terminal component of the electron transport chain. In eukaryotic organisms, CcO is composed of 12-13 subunits. The core of eukaryotic CcO contains three mitochondrially encoded subunits that comprise the catalytic core of the complex and several gene products encoded for by the nucleus (1). Essential to the redox function of CcO are several critical cofactors: two hemes and two copper centers (2). The crystal structure of CcO has led us to several insights about its structural components and catalytic activity (3). However, a large set of nuclear gene products are essential for CcO activity that are not part of the structural machinery of the complex (4,5). These components have been implicated in various stages of CcO assembly including, heme processing and insertion (6), CuA and CuB site delivery and insertion (7), subunit processing and subunit assembly (8,9). Among them are well characterized CcO assembly factors that involve the biogenesis of the CuA and CuB sites in CcO. Sco I, Cox17, Cox 11 and Cox23 are all essential to CcO activity and have properties that appear to be critical to the maturation of the CuA and CuB sites(10-13). Cmc4 appears to be involved in cytochrome c oxidase biogenesis. Peroxide phenotypes have been linked to cytochrome c oxidase assembly (14). Saccharomyces cerevisiae strains lacking CMC4 were found to exhibit peroxide resistance when compared wild type parental stains. Resistance was seen in liquid culture and in media containing glucose and glycerol. These results may indicate that cytochrome c oxidase assembly is altered in CMC4 deletion stains.

Daniel Gray, Utah Valley University Physics Mini black holes (BH) of various mass could be left over in space from the early expansion Big Bang phase (so called primordial BHs). As a result of interaction of those BHs with interstellar hydrogen they could form a bound system with an electron or a proton (or both). What would such system look like? Would it be stable, metastable, or would BH quickly consume the orbiting particle? How much is life time of such “gravitational atom”? If such system is stable then what is the size of it; how much is the bonding energy of its ground state (=ionization potential energy) and how much are the energies of its exited states? Are those atoms “gravitational atoms” observable? What other properties do they have? Based on known physics we try to analyze the behavior of such exotic systems and answer the above questions for black holes of various masses.

Michael Strange, Utah State University Geology For the past century, the standard technique used to interpret soft-tissue preservation in the fossil record has been the camera lucida drawing. A new technique called False Color Treatment (FCT), which uses digital photography and photo manipulation, shows an increased ability to not only interpret soft-tissue features but also identify trace amounts. Hyolithids from the Cambrian of northern Utah were used to test the capabilities of FCT. Results were then compared to camera lucida drawings of the same specimens. Comparisons show the camera lucida drawings missed areas of soft-tissue that FCT found. Depending on the specimen, and the type of preservation, this disparity in interpretations can increase or decrease. Hyolithid specimens from the Spence Shale show an odd form of Burgess Shale Type (BST) preservation which makes them particularly well suited for FCT manipulation. Overall, False Color Treatment provides an informative and aesthetic method for interpreting soft-tissue fossils with BST-like preservation.

Kelby Peterson, Utah State University Physics The State of Utah Space Environment & Contamination Study (SUSpECS) experiment flown on the Materials International Space Station Experiment 6 (MISSE-6) was an experiment designed to examine the consequences of the space environment on various materials used in space-component design. SUSpECS was comprised of approximately 180 samples that were suspended from the side of the International Space Station (ISS) for 18 months and returned to allow for pre- and post-flight comparisons. The sample with the most evident changes was a thin film of polyethylene terephthalate (PET) MylarTM coated with Vapor Deposited Aluminum (VDA). The post-flight analysis showed evidence of atomic oxygen erosion of the VDA layer, UV-induced discoloration of the polymer, and a crater created by a micrometeoroid impact. This presentation focuses on the UV-induced discoloration and laboratory tests to simulate these effects. The UV tests expose similar polymers to varying intensities of vacuum UV radiation from deuterium lamps over a condensed time span and quantify the discoloration of the polymers through comparison of the UV/Vis/NIR reflection spectra. The results from the UV simulation are used to determine the approximate time period of the UV exposure for the SUSpECS sample and in turn the erosion rate of the VDA layer.

Cathy Crawford, Utah State University Chemistry and Biochemistry In the spirit of many chemistry instructors’ longstanding interest in making teaching labs less “cookbook-like” and more research-driven, we recently restructured our second-semester sophomore organic chemistry lab to include a synthesis project that was chosen, designed, and carried out by students. Students were given the incentive of co-authorship on any publications resulting from their work. This led to the development of total syntheses of JBIR-94 and JBIR-125, new antioxidative/anticancer compounds with radical-scavenging potencies comparable to those of a-tocopherol, the active constituent in Vitamin E. Our presentation will summarize our progress and findings, and includes our progress on bioactivity studies conducted on the JBIR’s and their synthetic precursors.

Natascha Knowlton, University of Utah Chemistry The chemical derivatization of oxide surfaces (silica, alumina, glass) is critical to the development of separation media, sensing surfaces, or biocompatible interfaces. Presently, there are few analytical methods that allow the detection and characterization of functionalized monolayers on these surfaces. Raman scattering spectroscopy can provide useful structural information in the form of vibrational spectra of molecules of interest, and it is compatible with oxide substrates. Raman scattering, however, is a very weak effect so that its application to detecting monolayers is challenging. In this work, two approaches to detecting and characterizing molecular layers on oxide surfaces with Raman spectroscopy are compared. First, gold colloidal nanoparticles are deposited onto the surface of interest, which enhance the Raman scattering near the gold surface by surface-plasmon resonance. This technique is suitable for ex situ analysis of monolayers on planar surfaces. Secondly, monomolecular layers can also be detected by Raman scattering on porous oxide supports such as alumina or silica without any optical enhancement due to the very high surface area of these materials. Detection in porous particles is compatible with in situ monitoring of surface derivatization reactions. These two methods are compared for monitoring of reactions of silane-coupling agents and their subsequent functional group transformations on glass and silica surfaces.

Alyssa Brown, Southern Utah University Physical Science It has been long debated whether early astronomers could truly see any detail during their first observation and rough sketches of the satellites of Jupiter. Many have argued against the accuracy and validity of such drawings, claiming the lack of technological advance led to rough hewn and mediocre drawings with little evidence of these individuals having truly seen these satellites. Through our research, we hope to prove validity in those early sketches based on current knowledge. By converting the dates and times each early sketch was created into Julian Calendar days, then using the date obtained to calculate the position of each individual satellite of Jupiter, as well as the face that was approximately facing Earth at the time the sketch was made, we can compare current images to those previously obtained sketches. By analyzing the sketches for determining features as well as the relative location of those features in relation to their approximate location on the satellite face the astronomer was most likely observing, we can either validate or disclaim these early sketches. This experiment will provide beneficial insight into the accuracy of primitive sketches made centuries before more detailed information was discovered about the celestial bodies that continue to fascinate us. The information gained from this experiment may even lend a greater knowledge and understanding of how to study these celestial bodies, since if the information presented by these early sketches were accurate, we could potentially reevaluate the manner in which we currently conduct our present observation.

Paul Chidsey, Brigham Young University Chemistry and Biochemistry It has been reported that an estimated 11% of women in the population have undiagnosed endometriosis, emphasizing the need for early detection tests and treatment options. Diagnosis is typically determined through an analysis of symptoms, including painful menstrual cycles, pain in the lower abdomen, and prolonged menstrual cramping. Diagnosis is further confirmed through invasive procedures such as transvaginal ultrasound and pelvic laparoscopy. Serum proteomic studies in which small biomolecules and peptides are analyzed for biological significance in endometriosis cases and controls can lead to the discovery of novel methods whereby the disease is detected and eventually treated earlier in development without the need of invasive procedures. Comparative analysis of cases and controls through mass spectroscopy has led to the discovery of novel biomarkers capable of correctly identifying individuals with endometriosis. Further pursuing this study will allow for a greater understanding of the genesis of the disease, eventually uncovering the mechanism whereby endometriosis develops.

Jim Goodman, Westminster College Chemistry Mercury is a toxic element that adversely impacts the health of wildlife and ecosystems worldwide. While all forms of mercury are toxic, methylmercury is the only form of mercury that is biomagnified, and thus organisms with the highest mercury concentrations and most at risk to mercury toxicity are typically the top predators in an ecosystem. To evaluate if arachnids, a top predator in the insect realm, are bioaccumulating mercury a spatial and temporal study of mercury bioaccumulation in arachnids and terrestrial invertebrates was conducted at the Great Salt Lake. Total mercury (HgT) and methylmercury (MMHg) concentrations were measured in arachnids collected once each month from two different sites on Antelope Island in the Great Salt Lake, and at a control site at Utah Lake, a fresh water lake to the south where mercury concentrations in the water column are substantially lower. Average concentrations of HgT and MMHg in arachnids from Antelope Island were 2600 ± 497 ppb and 1690 ± 169 ppb, respectively. These were significantly higher than the HgT and MMHg concentrations in arachnids at Utah Lake, where they are only 72 ± 54 ppb and 42 ± 30 ppb, respectively. Substantial spatial variation in HgT and MMHg concentrations in arachnids at the two sites on Antelope Island was also documented, and may be due to differences in the abundance of brine fly prey at the different locations.

Jacob Wright, Utah Valley University Physics Dissonant overtones of closed bottle-shaped thermoacoustic prime movers are discussed. The resonator consists of two concentric cylinders with differing cross-sectional areas, closed at the outer ends. The condition for resonance results in a transcendental equation, which is solved numerically. The neck and cavity behave as coupled resonators, where the neck is a quarter-wave resonator and the cavity is a half-wave resonator. A variable cylindrical cavity with a sliding piston was constructed to study the nature of the device as the cavity length is varied. The stack is located in the neck region and the length and inner diameter of the neck are 5.39 and 1.91 cm, respectively. The inner diameter of the cavity is 4.76 cm and has a maximum length of 38 cm. The dominant mode of operation depends on the length of the cavity, favoring successively higher modes as the cavity length increases. The volume filling factor of the stack material was varied from 2 to 5% to determine whether the amount of stack material affects the transitions. These filling factors were selected to yield hydraulic radii comparable to the thermal penetration depth for the highest and lowest possible fundamental frequencies of the system. The transition to higher modes occurs roughly where the higher mode overlaps with the fundamental frequency of the neck region, and is independent of the stack filling factor. With the given dimensions, three transitions to higher modes were observed, with frequencies consistent with the model.

Brennan Young, Utah State University Geology Thermal springs in northern Utah and southeastern Idaho mostly lie near active or inactive Basin-and-Range normal faults. They are dynamic systems, and the character of some has changed drastically since work as early as the 1980’s (Blackett and Wakefield, 2002; IDWR, 2001). We examined and sampled 60 thermal springs and most samples met criteria for cation geothermometers, or mathematical-geochemical tools used to estimate the maximum temperature of hydrothermal reservoirs. Of the 60 springs, 51 met criteria for the Na-K-Ca geothermometer and the remaining nine springs did not meet the criteria for the K-Mg, Na-K, Na-K-Ca, or Na-K-Ca-Mg cation geothermometers used in this project (Fournier and Truesdell, 1973; Fournier and Potter, 1979; Giggenbach, 1988). Of those 51 springs, only one is considered to be in partial equilibrium with the thermal reservoir, and estimates a reservoir temperature of 79°C (Giggenbach, 1988). Though the majority of springs exhibit a chemical signature of having mixed with shallow groundwater (Giggenbach, 1988), the Na-K-Ca geothermometer gives the most reliable results for springs in northern Utah and southeastern Idaho, but only for springs with surface temperatures exceeding 30°C and with greater than 1000 ppm total dissolved solids (TDS). Geothermometer results for these springs yield reservoir temperature estimates between 193 and 249°C.

Rachel Nydegger, Utah State University Physics Multi-messenger astronomy employs both electromagnetic and gravitational-wave detectors to paint a richer picture of celestial objects, providing more depth and information. The interferometers utilized for gravitational-wave observations receive input from very broad fields of view on the sky, typically a few square degrees. To have simultaneous electromagnetic observations (typically less than one square degree) requires innovative techniques for the telescopes to find the origin of radiation. One idea is to “tile” the view of the interferometer, using multiple telescopes to simultaneously point at different areas of the field to observe the source. One difficulty of this observing paradigm is distinguishing random electromagnetic variable sources from a gravitational-wave counterpart. To better understand this problem, this project repeatedly observes a single field on the sky. Each observation is analyzed to count the number of sources that appear in the field as a function of brightness. Repeating this process over time will yield the frequency of random optical transients, as well as characterize the population and brightness distribution of variables in the field. Future work will extend this observation campaign to cover different galactic latitudes.

Ben LaRiviere, Utah State University Geology The DOE-funded HotSpot Project out of Utah State University has collected a more than mile-deep core from the central Snake River Plain, Idaho, to study the geologic history of the area. The core consists mostly of volcanic basalt, however 16 sediment layers have been identified and sampled between the basalt-flow layers. These layers of sediment are the key to understanding environmental conditions on the Snake River Plain between basalt flows. The sediment was sampled in 25cm increments and the grain size of the sediments were examined in a laser particle size analyzer to better understand depositional conditions on the snake river during the past 5 million years. The analysis revealed that the majority of the sediment was deposited as windblown silt with several fluvial deposits.

Joseph Jensen, Utah State University Physics The earths ionosphere is very important in our everyday life. During large solar flares the ionosphere expands to the point of disrupting communications from GPS, military, and commercial communications satellites, and even radio blackouts can occur. The EVE instrument on the SDO satellite has given unprecedented spectral resolution for the Extreme Ultraviolet (EUV) spectrum with a time cadence of 10 seconds. This has made it possible to analyze flare spectra as never before. Using the Time Dependant Ionospheric Model (TDIM) we have input this new spectral data for large solar flares and analyzed the effect on the ionosphere. We take as a test case the X1.6 flare on March 9, 2011. Even this minor X-class provides insight into how the ionospheric layers respond differently to solar flares.

Kent Hartley, Utah State University Physics Faraday cups provide a simple and efficient apparatus to measure the absolute magnitude of charge particle fluxes, and with the addition of a retarding field analyzer and defining apertures the capability to determine the energy and angular distributions of the fluxes. Through careful design of the electron optics, a Faraday cup can be tailored to meet specific requirements for detector size, minimum detectable flux, collection efficiency, absolute accuracy, energy discrimination, and angular resolution. This work explores design concepts through electric field and charged particle trajectory simulations, theoretical analysis, and evaluation of experimental prototypes to develop compact, high efficiency Faraday cups capable of a range of energy and angular resolutions. The designs rely on high efficiency Faraday cups coupled with grid-free Einzel lens energy analyzers for nearly energy-independent determination of absolute fluxes. We also review specific designs and applications of these Faraday cup detectors to electron emission and transport studies, spacecraft charging applications, and electron beam characterization measurements done in conjunction with various projects conducted by the Materials Physics Group.

Ryan Smith, Brigham Young University Geological Sciences Bhutan, a remote country in the Himalayas, has an underdeveloped economy that relies heavily on hydro-electric power and agriculture. Glacial lake outburst floods, or GLOFs, threaten both of these sectors of their economy. More importantly, they threaten human lives. In this study, I will estimate the increase in volume of the most rapidly growing glacial lakes in the Bhutanese Himalayas and investigate potential causes of their growth. In addition, I will develop a simple model to simulate the flooding effects of a GLOF on downstream cropland and villages.

Lisa Heppler, Brigham Young University Chemistry and Biochemistry Solid breast tumors contain heterogenous microenvironments where tumor cells are often exposed to metabolic stress (e.g., hypoxia due to poor blood supply). Such environments select for tumor cells that can adapt metabolically to survive, while other cells fail to adapt and undergo cell death. The survival of cells through periods of hypoxia can promote chemoresistance and metastasis (1). Thus, it is critical that we develop therapeutic strategies to enhance metabolic-stress-induced tumor cell death. One promising strategy is the modulation of lysine acetylation pathways by HDAC inhibitors that potently pro- mote cell death in response to various stimuli, including hypoxia/glucose withdrawal. Given the relatively non-specific nature of chemical HDAC inhibitors, the precise acetylation-regulating enzymes and pathways that govern cell death in these settings have yet to be fully elucidated. Our goal is to identify the cellular factors that link acetylation to cell death in response to hypoxia and other metabolic stresses, with the hope that such factors could be exploited therapeutically in cancer. Previous studies have implicated protein lysine acetylation in the coordination of cellular metabolism to the available nutrient supply (2). In line with this idea, our preliminary data suggest that lysine acetylation pathways dictate whether breast tumor cells survive (through metabolic adaptation) or die in response to hypoxia and glucose deprivation. Moreover, we have observed that general increases in protein lysine acetylation precede the activation of pro-apoptotic caspases in response to these stresses. In addition, our proteomics efforts have shown that breast tumors that are sensitive to hypoxia/glucose withdrawal exhibit significant increases in acetylation across the proteome, whereas resistant cells show very little change. Together, our data suggest that lysine acetylation pathways play a role in metabolic adaption and survival under conditions of hypoxia/glucose withdrawal. We are currently using an RNAi approach to target all known deacetylases, acetyl-transferases, and metabolic enzymes that modulate acetylation (e.g., acetyl-CoA synthetase) in order to identify the specific acetylation-regulating factors that govern tumor cell susceptibility to metabolic stress.