2013 Abstracts

Jennifer Nhan, University of Utah College of Health, Division of Endocrinology, Metabolism, and Diabetes The overall goal of our laboratory is to elucidate mechanisms whereby endothelial nitric oxide (NO) synthase (eNOS) enzyme function and NO bioavailability are impaired in individuals with diet-induced obesity (DIO), type 2 diabetes (T2DM), and insulin resistance. This is a clinically relevant issue because all of these conditions are associated with poor vascular function that might be precipitated by disrupted eNOS enzyme function and NO bioavailability. To study this issue we use model systems including cell culture, isolated arteries, and rodents. It is important to have an accurate, reproducible, and sensitive method to detect NO in each of these systems. The purpose of my work was to optimize the technique of electron paramagnetic resonance spectroscopy (EPR) to assess NO in bovine aortic endothelial cells (BAECs). NO contains an unpaired electron. This structural feature facilitates the measurement of NO via EPR. NO is detected with a spin trap of FeSO4 and diethyldithiocarbamate trihydrate (DETC). In the presence of NO, the spin trap forms a NO-Fe(DETC) complex which is detected by EPR. BAECs were grown to 70-80% confluency in six-well plates, and treated with: (i) vehicle (buffer only), (ii) 600 uM of insulin (an NO agonist), (iii) 10 uM of NG-monomethyl-L-arginine acetate salt [LNMMA, an NO synthase (NOS) inhibitor], and (iv) three doses (1, 10, 100 uM) of diethylammonium (DEA) NONOate (an NO donor) to serve as a positive control. All treatments contained L-arginine [the substrate for endothelial NOS (eNOS)] and FeSO4 (the spin trap). After a 60-min incubation with treatments (i) (iv), cells were dislodged from each plate, collected, frozen in liquid nitrogen, and NO was detected using EPR. Relative to vehicle treatment, 1uM, 10uM, and 100uM DEA NONOate increased NO production by 50±8%, 150±2%, and 700±26% (p<0.05) respectively. Insulin increased (p<0.05) NO production by 73±4% vs. vehicle, and this response was prevented in cells treated with insulin + LNMMA. These results indicate EPR is a suitable method to detect cellular NO production. My next project is to optimize this technique for use in isolated arteries from experimental animal models.

Kara Vickers, University of Utah Nursing Symptoms related to cancer and its treatments are a significant source of distress for children and adolescents with cancer. Although children and adolescents may receive interventions aimed at alleviating symptoms, the hospital care environment itself may be one that adds to the overall symptom burden. The purpose of this study is to investigate relationships between symptoms experienced by hospitalized children and adolescents with cancer and the care environment on an inpatient pediatric oncology unit. This prospective, descriptive study uses use a repeated measure, within-group design to identify relationships between symptoms and the nursing care environment that can be used to guide future interventions. Participants are 50 children and adolescents (7 to 18 years of age) with cancer. Data collection is occurring over a 3-day and 3-night period. Children and adolescents’ symptoms are measured each shift using the Memorial Symptom Assessment Scale for patients aged 7-12 years. Participants also answer two open-ended questions about what has bothered them about the hospital environment and what they perceive could improve the hospital environment. Sound and light levels are measured continuously using a sound pressure level meter and data logger placed approximately 48 inches from the child’s bedside. Nursing care activities are measured through counts of care activities occurring during room entries by nursing staff. Room entries are identified using an Axis pan-tilt-zoom (PTZ) dome camera. A member of the research team reviews the child’s nursing flow sheet, medication administration record, acuity level, laboratory values, and medical orders each day. Data is presently being collected and will be analyzed using hierarchical mixed effects statistical models. Long-term goals of this project include improving symptom management in the inpatient setting, minimizing modifiable factors in the care environment that cause greater symptom burden, and lastly use the findings to inform hypotheses for a larger intervention studies. Hopefully these studies will target structuring the hospital care environment to minimize the symptom burden experienced by hospitalized children and adolescents with cancer and, ultimately, promote their quality of life.

Jacqueline Rodriguez, University of Utah Health Promotion and Education This is the second phase of an anticipated multistage research study. The first phase was completed Spring of 2012 and data showed that drivers of personal vehicles were having a difficult time hearing Emergency Medical Service (EMS) vehicles when driving with their radio on or while operating a hands-free cell phone which may be a leading factor in many of the estimated 9,000 EMS accidents a year. Information will be collected from accident reports and personal interviews will be conducted with EMS personnel who have been involved in a vehicular accident while driving an EMS vehicle. Similarities found in the interviews and accident reports that may explain why vehicular accidents involving EMS occur will be recorded. The accident reports which will be analyzed will have occurred in the past five years and will have transpired within the State of Utah. One-on-one interviews will be conducted about the accident in the State of Utah and with EMS personnel that have been in a vehicular accident in the past 5 years while driving an EMS vehicle. It is hypothesized that many of the vehicular accidents involving EMS drivers occur due to drivers in personal vehicles not noticing EMS vehicles in enough time to clear the way. It is believe the results gathered from the interview and accident reports will show that drivers do not see/hear EMS vehicles very well when distracted. In the cases where the EMS driver was found at fault for the accident, it may be due to having to resort to unsafe driving practices because they are responding to an emergency and the drivers in personal vehicles are not moving out of the way in a timely manner or simply not at all. It is anticipated that the results of this study should be available late December.

Arlene Johnston, Brigham Young University Nursing Description:

Elizabeth Johnson, University of Utah College of Health, and Division of Endocrinology, Metabolism, and Diabetes Constant-flow left ventricular assist devices (LVAD) are implanted in heart failure patients to assist the heart in pumping blood through the body either temporarily as a “bridge” mechanism until a heart transplant or permanently as a destination therapy. The blood flows constantly with an LVAD contrary to the natural pulsatile flow of the human heart. We wanted to determine if this constant flow attenuated the function of the arteries. A transmural biopsy was taken from seven male patients (52±6 years old) when the LVAD was implanted (pre) and again 142±2 days later upon LVAD explant (post). Arteries were obtained from the pre and post tissue biopsies. Vessel function was assessed using isometric tension techniques. After Lmax tension was determined for each vessel, the contraction-response curve of each vessel was tested using potassium chloride (KCl, 10-100 mM). Next the vessels were pre-contracted to ~65% maximal tension and treated with bradykinin (BK, 10-6 to 10-10 M) and sodium nitroprusside (SNP, 10-4 to 10-9 M) to determine, respectively, endothelium-dependent and -independent vasorelaxation. Maximal KCl-evoked contraction (0.99±0.22 and 0.69±0.14 mg tension development / μm vessel length), maximal BK-evoked vasorelaxation (64±13% and 80±7%), and maximal SNP-evoked vasorelaxation (92±3% and 92±4%), was similar in arteries obtained from pre (n=13 arteries, 206±40 μm i.d.) and post (n=14 arteries, 288±24 μm i.d.) transmural biopsy samples, respectively. These preliminary data indicate that coronary vascular function is not attenuated by LVAD implantation.

Samantha Webber, Brigham Young University Nursing Background: In November of 2012, a small group from BYU’s College of Nursing returned to Guayaquil, Ecuador to measure anemia indicators post interventions in school age children. In May of 2012 a larger group, including students, from BYU’s College of Nursing had visited Guayaquil for the fourth consecutive year to assess malnutrition and anemia rates in school age children. This multi-phase research project which began in May of 2009 found that nearly 41% of the children in this area suffered from anemia (below 11g/dl as per WHO guidelines). The adverse effects of anemia for these children can include: weakness, fatigue, shortness of breath, and poor concentration. Anemia may result from deficiencies of iron, B12, folic acid, and may also be the result of intestinal parasites. A nutrition survey conducted among these same school children showed that daily intake of iron, B12, and folic acid were below recommended levels. Intervention: In May of 2009 Hogar de Cristo (HDC), a non-profit organization, began distributing 6 to 8 ounce bottles of soy milk as a school snack for each school-aged child at a few of the schools in the area. A local pharmaceutical company who supplied vitamin and iron supplements during the first year of the soy milk distribution, reassessed anemia rates in those children in November of 2009. The BYU College of Nursing continued to assess school- aged children for measures of anemia and growth and development in 2010 and 2011 as directed by Hogar de Cristo. After 2011 it was difficult to correlate anemia and soy milk because of changes in the sample from year to year. In May of 2012 the BYU College of Nursing shifted their focus to four interventions with the aim of determining which one would best lower anemia rates. The study focused on students at four schools in the perimetral area, each school received one of the interventions as an adjunct to soy milk: vitamin supplements, antiparasites, vitamins and antiparasites, and a control group (soy milk only). Growth and development measures along with rates of anemia were reassessed in November 2012. Results: In May of 2012 the BYU College of Nursing tested 1041 school-ages children for growth and development and anemia. growth and development rate results spanning the four years of testing, and a comparison of anemia rates between intervention groups and control groups.

Ashlee Manwaring, Brigham Young University Nursing Purpose: To examine how the new policy of Medicare/Medicaid reimbursement being based on HCAHPS scores affects nursing care. Rationale: The Patient Protection and Affordable Care Act (PPACA) mandates that Medicare and Medicaid reimbursement be based on hospital performance and patient satisfaction. Patient satisfaction is measured nationally through the Hospital Consumer Assessment of Healthcare Providers and Systems (HCAHPS) survey. The HCAHPS survey was development in the early 2000’s to create a uniform measure for patient perspectives regarding their inpatient stay; however, with the HCAHPS scores being related to Medicare and Medicaid reimbursement, hospitals are required to reevaluate their quality of care from the patient, not medical, perspective. Van Empel et al. (2011) found that physicians and nurses primarily value medical outcomes of treatment. While, at the same time, patient’s value patient-centeredness, even if it means decreasing the desired outcome of treatment. Undertaking: A literature review was completed by searching in CINAHL and Medline. Preliminary research used HCAHPS and Medicare reimbursement as key words. Second, a search was completed using HCAHPS and nursing as key words. All results were published between 2008 and 2012. Outcomes: Kutney-Lee et al. (2009) reported that patient satisfaction was primarily linked with nurse-to-patient ratio, interdisciplinary collaboration and work environment. Research by Robinson and Watters (2010) found the main factor in patient dissatisfaction was feeling like the nurses were short staffed, task-oriented and rushed, leaving the patient lacking adequately communication to understand their situation. Van Empel et al. (2011) reported patients’ willingness to change providers and facilities to received patient-centered care. Conclusion: Nurses have the greatest potential to effect patient satisfaction. Therefore, with the new regulation of Medicare and Medicaid reimbursement based on patient satisfaction surveys, nurses have a greater responsibility to ensure patient satisfaction. From the research presented, the main nursing implication is to help each patient feel like their care is centered on what is important to that individual. This can most easily be accomplished by the nurse opening a line of communication with the patient, and then advocating for the patient’s wishes.

Cami Schiel, Brigham Young University Nursing 65 French hospital nurses in Avignon, France were surveyed about their opinions about healthcare. Survey results identified and described French nurses’ perceptions of their health care system as well as other systems. Access to care was a positive aspect of their healthcare system that was identified by a majority of the respondents. Abuse or lack of oversight, and budget deficit were major themes identified as negative aspects of the French healthcare system. The French nurses’ opinions about different countries’ health care systems were compared to World Health Organization [WHO] (2000) rankings. French nurses overwhelmingly ranked France’s healthcare system as number one, which matched the WHO (2000) ranking. 73% of respondents prioritized preventative care over acute treatment. Work and other professional peers were identified as the main sources of influence on French nurses’ perceptions of health- care both French and internationally. Nurses’ opinions heavily influenced other nurses in the workplace. An implication from this study is that nurses can have a powerful impact on others’ viewpoints about healthcare. They are also a valuable resource for identifying strengths and weaknesses of a healthcare system, given their lived experience working in the healthcare system.

Jordyn Whiting, Brigham Young University Nursing Purpose: To demonstrate use of a guide to help nursing students increase cultural competency gained during study abroad programs.Background/significance: In a world of increasing globalization, nurses are more likely to care for patients of a cultural background different from their own. To care for increasingly diverse patients, nurses need greater cultural competence to provide the safest and highest quality of care possible. Study abroad programs have been shown to be an excellent way to provide cultural education for students. The number of students choosing to participate in these programs has more than doubled in the last ten years. However, no research is available from a student perspective on how to plan for an optimum learning experience during study abroad. A research-based guide, from a student perspective, will help students take better advantage of experiences abroad to increase cultural competency. Methods: A literature review using online databases (including CINAHL and MEDLINE) was conducted using search terms such as nursing student, student, cultural competency, cultural sensitivity, cultural awareness, study abroad, international experience, and exchange program. Articles from the online search were used to compile a student guide. The guide includes competence-enhancing activities, formulated using brief anecdotal summaries and trending study abroad outcomes found in the articles. The guide’s framework came from Josepha Campinha-Bacote’s 2002 article, “The Process of Cultural Competence in the Delivery of Healthcare Services: A Model of Care,” and its subsequently updated versions (2007 and 2011). With the original version of the guide, there were 16 activities in four categories: cultural awareness, cultural knowledge, cultural skill, and cultural desire. The guide also included 16 blank squares where students could create their own activities. The guide contains a small reflective writing portion where students can think about their experiences as a whole and how they can implement what they learned into practice. A total of 12 students, including the author, used the guide in two different study abroad programs, first while participating in a Global Health and Human Diversity program with the College of Nursing in Tonga in May 2012.

Laura Gilpin, Brigham Young University Nursing Purpose/Aims: The purpose of this pilot study was (1) to examine nursing students’ perceptions of their first experience with death in the clinical setting and (2) to determine if curricular changes are necessary to better prepare nursing students effectively cope with their first death experience as a nurse. Background: Death, particularly the unexpected death of a patient, is an emotionally charged, high-stress situation for any nurse. Nursing students encounter scenarios involving death and dying in simulation laboratories, as well as in the clinical setting. In simulation settings debriefing is routinely accomplished and is seen as a critical component of the learning experience. However, Leavy and colleagues (2011) found that even during formal simulation debriefing sessions nursing students were not able to fully process their emotions In real-life clinical settings, the stakes are even higher as nursing students must be able to effectively cope with the death of a patient. Unfortunately, research on students’ first experience with death is limited. Huang and colleagues (2010) found students may not receive adequate support from clinical nursing instructors during the dying process and after a patient’s death. Methods: This was a descriptive mixed methods pilot study. An online anonymous survey was sent to students in the Brigham Young University College of Nursing regarding their first experience with death in the clinical setting (N=306). Students were e-mailed a brief description of the research project and an invitation to participate in the study only if they had experienced the death of a patient. Completion of the online questionnaire implied consent. The participants answered 5 demographic questions and 11 survey questions with the estimated time commitment for each participant being 15 minutes. Results: The online questionnaire was sent to 306 BSN nursing students Approximately 10% initially responded (N=33). A smaller group (N=25) completed the entire survey. Qualitative comments from nursing students who experienced the death of their patient included feeling sad, shocked and uncomfortable. Fifty percent of the nursing students did not receive any debriefing from their clinical instructor following the event.

Heather Peatross, Southern Utah University Agriculture and Nutrition Sciences Complementary and Alternative Medicine (CAM) is defined as any ingestible herb, supplement, or other substance used to increase one’s health or well-being both physically and mentally. National studies have examined the usage of CAM. In 2007, the latest year surveyed by the National Center for Complementary and Alternative Medicine (NCCAM), approximately 38% of adults in the U.S. were using some form of CAM with the greatest usage among women and persons with higher education and income levels. Non-vitamin/mineral natural products are the most commonly used CAM therapies. Americans spent $33.9 billion out-of-pocket on CAM over the previous 12 months. Little information regarding CAM use and knowledge in a rural college-age population is available. The purpose of this study is to examine the knowledge Southern Utah University (SUU) students have of CAM, usage by this population, and the reasons for using these products. Do SUU students typically use CAM therapies in their daily lives? Do SUU students use CAM primarily when ill? Are SUU students using CAM as a replacement for traditional (western) medicine? What types of CAM are being used (particularly herbal or dietary supplements)? It is hypothesized that the majority (>50%) of CAM users do not discuss their alternative therapies with a health care physician. Additionally it is hypothesized that students that have been diagnosed, or have a family member that has been diagnosed, with cancer are more knowledgeable/more likely to have used CAM therapies. Four hundred and eighty students were surveyed in a convenience sample of fourteen general education classes at SUU. The survey asked about usage of CAM therapies (including for health or sport performance), overall experience with CAM products used, sources of health advice, and any discussion with their medical physician regarding CAM use. Study results and conclusions are pending.

Jacob Robinson, Brigham Young University Mechanical Engineering Figure skating is a competitive sport that requires athletes to practice up to 5 days a week year round performing 50 to 100 jumps per day. This results in high, repetitive impact forces on the skater’s body which may lead to overuse injuries. While the negative effects of figure skating are well documented, the cause of these injuries is still unclear because the complexity of artistic figure skating limits current instrumentation from accurately measuring impact forces. This project has sought to fill this void by developing a force measurement system that will allow the figure skater to perform their jumps without any hindrance while accurately measuring the magnitude of the impact forces in the vertical and horizontal directions. Using strain gauges attached to the stanchions of the ice skate combined with a data collection system that attaches to the bottom of the boot, we have developed a prototype that accurately measures the forces produced in the ice skate. This will lead to a fully developed ice skate measurement system which will be used by researchers to investigate the impact forces generated in figure skating jumps and landings.

Connor George, Utah State University Electrical and Computer Engineering The SABER instrument, aboard the TIMED satellite, measures optical data regarding parameters of the Earth’s atmosphere with respect to altitude. Approximately once per minute, SABER performs a limb-scan measurement on the Earth’s atmosphere from which altitude emission profiles of key atmospheric gasses, including hydroxyl at wavelengths of 1.6 μm and 2.0 μm, are derived. Most hydroxyl profiles within the SABER dataset contain a single peak in the airglow altitude profile centered near an altitude of 87 km, but a significant portion of the profiles display two or more local maxima. MATLAB code was written to analyze the geophysical and temporal global distribution of the multiple-peak profiles. Graphs have been created which display relationships between the percentage of multiple-peak profiles and the local time, the cardinal orientation of the SABER device, and the latitude and longitude at which the atmospheric profile was measured. Patterns have been observed in multiple-peak profile distribution with respect to these variables. Possible causes of the multiple-peak occurrences in the hydroxyl altitude profiles include waves, geometrical effects of the SABER instrument, and/or chemistry of the atmosphere. In addition to graphing software, analysis software was written which counts the number of peaks present in any given altitude profile, and which ascertained the percentage of profiles displaying multiple-peak characteristics. A small (<1%) portion of hydroxyl altitude profiles were found to have abnormal distributions due to erroneous or noisy data collected by SABER. Software has also been written to remove such exceptions from the dataset. Additional investigation into the relationship between multiple-peak occurrences and cardinal direction orientation of the SABER device is required in order to further identify the causes for multiple peak profiles. An investigation into seasonal patterns for multiple-peak profiles is to be conducted. As the dataset grows, exception software will be updated to identify invalid altitude profiles. Also, ozone has been found to have multiple-peak altitude profiles similar to those of hydroxyl, and studies complementary to those performed on hydroxyl altitude profiles will be performed on ozone.

Derek Chang, University of Utah Bioengineering Atrial fibrillation (AF), the most common cardiac arrhythmia, is a rapid, irregular heart beat arising from uncontrolled and asynchronized electrical activation in the atria. This disruption of the normal electrical signaling hinders the contraction of the heart, leading to decreased blood flow, possible clot (thrombus) formation, and an increased risk of stroke. The left atrial appendage (LAA) is a small muscular pouch of highly variable anatomy within the left atrium. The LAA plays a prominent role in thrombus formation in patients with AF because of decreased blood flow within this structure. Thus, we hypothesized that the shape of the left atrial appendage is different in AF patients with a documented history of stroke. We used statistical shape analysis to determine which LAA shape variations contribute to stroke based on a cohort of AF patients who had both MRI and CT scans and a documented history of stroke. We manually delineated the boundaries of the LAA from each patient’s CT and MRI scans to analyze the resulting LAA segmentations for shape variations across imaging modalities and history of stroke. The results showed that patients who have AF and a history of stroke have an LAA with a narrower insertion site into the left atrium and are larger in size. In contrast, patients who have AF, but no history of stroke, have an LAA with a wider insertion site, which are smaller in size. By isolating specific LAA shape variants indicative of an underlying risk of stroke, we can use this shape classification scheme to better tailor AF therapies to each individual patient.

Autumn Pando, Brigham Young University Mechanical Engineering The wrist is one of the most common sites for joint injury. Over two-thirds of 75,000 annual repetitive joint injuries occur at the wrist. Excessive or abnormal wrist forces are thought to be one of the main contributing factors, yet no characterization of normal wrist forces exists. The purpose of this research is to fill this lack by creating a systematic, quantitative characterization of wrist forces and torques experienced in daily life. This database will aid further research in developing better and more personalized treatments as well as improving design considerations for human-machine interfaces. Ten healthy subjects participated in the experiment. Subjects performed 25 activities representative of daily life (e.g. hygiene maintenance, food preparation, using technology). Electromyographic (EMG) sensors recorded wrist muscle activity and electromagnetic motion sensors recorded wrist kinematics. Each subject performed a calibration task prior to the experimental protocol to determine the proportionality constant between EMG activity and torque. Wrist force and torque were determined from EMG activity using a constant of proportionality (identified by calibration), muscle length, and muscle velocity. Co-contraction was computed from torque. Wrist muscle usage, forces, torque magnitudes, torque angles, and percentage of co-contraction at varying levels of contraction were characterized. The results indicate muscle use, forces, and torques are unevenly distributed.

Mitchell Dabling, Utah State University Civil and Environmental Engineering Water management and flood control are essential elements of civilization. Linear weirs (e.g. ogee crest, sharp crested, and broad crested weirs) are often used in irrigation channels or reservoir spillways to regulate the discharge and upstream water level during flood flows. As hydrologic data sets increase in size and accuracy, the highest probable maximum flood (PMF) discharge is becoming increasingly more accurate, and in many cases much larger than previous estimates. Because of this, an older weir may need to be rehabilitated to ensure it can pass the updated PMF discharge safely without upstream flooding. A nonlinear weir (e.g. labyrinth or piano key weir) can replace a linear weir in a channel or spillway to pass significantly more discharge without requiring increased channel width. The Utah Water Research Laboratory at Utah State University, with the help of Utah Mineral Lease Funds, has developed and published design data for multiple configurations of nonlinear weirs. In 2012, the Utah Division of Water Resources used this data to design a labyrinth-style nonlinear weir that will replace the spillway currently in use at Millsite Reservoir in Emery County. This rehabilitation project will significantly decrease the flooding potential of the surrounding area.

Kay (Beau) Freckleton, University of Utah Mechanical Engineering Current quad-rotors provide excellent maneuverability and opportunity for data collection in large scale areas such as agriculture, but lack the capability to maintain flight for an extended period of time. This is due primarily to a lack of energy supply, requiring operators to replace the battery source before the quad-rotor completes its designated purpose [1]. In this paper, we introduce a mechanism to enable flying robotic rotorcraft, such as quadrotors and helicopters which utilize vertical takeoff and landing, to perch similar to a bird. The mechanism is passive, using only the weight of the rotorcraft for actuation. Such a mechanism will dispel the need for multiple batteries by allowing the quadrotor to perch amid its designated flight course, recharge using solar energy, and complete data collection over large scale areas in less time. In previous research to this same end, biomimetic approaches were pursued, resulting in designs that looked similar to the legs and feet of birds. The design in this paper utilizes a Sarrus mechanism to convert rotorcraft weight into perch grip. We began by designing the mechanism for a range of cylindrical perch sizes. Using MATLAB, we developed a program to optimize the various mechanism dimensions needed to perch within this range while also maximizing the mechanical advantage of grip force. Using SolidWorks, a 3-dimensional model was created and manufactured with these dimensions. In testing, the mechanism successfully allowed a small RC helicopter to perch on a 4cm diameter rod with some resistance to external forces. However, in crash tests, the mechanism was unable to withstand certain moment forces and developed large fractures. Further research will focus on decreasing these moment forces’ ability to weaken the mechanism while optimizing perching capability.

Kimberly Uchida, University of Utah Bioengineering and Oncological Sciences Programmed cell death 4 (PDCD4) loses its function as a tumor suppressor when co-expressed with a specific binding partner, protein arginine methyltransferase-5 (PRMT5). A better understanding of the regulation of PDCD4-PRMT5 interaction may lead to cancer therapies targeted at restoring the tumor suppressive function of PDCD4. Using Xenopus laevis (frog) eggs to generate extract trapped in either interphase or mitosis, we found that PDCD4-PRMT5 interaction is regulated by the cell cycle. Full-length PDCD4 bound PRMT5 more robustly in interphase than in mitosis. However, a truncated version of PDCD4, that retained the PRMT5 binding site, bound PRMT5 equally in interphase and mitosis. These results indicate that there may be a component of full-length PDCD4 that occludes the PRMT5 binding site in mitosis. Furthermore, we found that both full-length and the truncated PDCD4 are preferentially phosphorylated in mitosis, but preferentially methylated in interphase. From these results we speculate that phosphorylation of PDCD4 in mitosis allows PDCD4 to fold upon itself and effectively block the PRMT5 binding site. Additionally, phosphorylation may prevent methylation even when PRMT5 can bind PDCD4, explaining the lack of PDCD4 methylation in mitosis. Such an inhibitory mechanism may be useful in therapeutically restoring the tumor suppressive function of PDCD4. Future research will be aimed towards completing our understanding of PDCD4-PRMT5 interaction in the cell cycle, such as proving our model in human cells.

Rodolfo Rafael, Weber State University Performing Arts In preparation for choreographic projects for my degree, I attended the world-class Ririe-Woodbury Dance Company workshop on an undergraduate grant. The workshop included various subjects, but the most valuable and challenging approach was the emphasis on the “frame” of a work of art and how by changing the frame, the meaning and impact of art is affected. I became interested in the artistic and societal frame of marriage, and decided to use this frame for my student choreographic project. Since it was in an academic setting, I presented the idea in an open-ended manner, one that allowed the students to express their concerns. I was intent not so much on the outcome of the piece, but that the subject of marriage be questioned. I started by having a discussion with the students. I solicited and noted their boundaries. After finding an agreed upon point of compromise on how to approach this issue, we decided to move forward. Unfortunately, some never came back. In fear of losing more students, I changed directions. This experience brought me to a new issue. How much academic freedom do students have? Is higher education supposed to provide a platform where students are free to explore open inquiries? What if others aren’t willing to deal with social issues? Should students change the subject matter of their research to avoid offending others? How do we encourage others to discuss issues they don’t agree on? Is there a way we can find common ground and share the frame?

Kelsey Spaulding, Weber State University Interior Design Research states that the youth in almost any setting, will always need attention and assistance in navigating life. Pre-teen and teen years can be a time when children need attention, guidance, and direction while developing into mature citizens of their community and world (Larson, Positive Development in a Disorderly World, 2011). Within schools, adolescents are taught only a few of the fundamental ideas and practices that would help them to better navigate in an ambiguous world. In a study done by the New York State Afterschool Network, learning opportunities outside of the classroom help to increase the application of lessons and give adolescents a higher probability for achievement (Network, 2012). Outside of school, adolescent youth need to be able to interact with each other and gain an understanding of themselves and others in relation to the world. Without an interaction with other youth and different aspects of society, adolescents may become apathetic and lack an understanding of the effect they may have on others and their community (Balsano, 2005). In Ogden, Utah, there are a variety of cultures and backgrounds from which adolescent youth come (Bureau, 2012). It is important during the age of adolescence to interact in a personal, societal, and healthy environment during the time when their brains and personalities develop most (Larson, Adolescents’ Development of Skills for Agency in Youth Programs: Learning to Think Strategically, 2011). When given the proper tools, guidance, and opportunities to work with others and their community, adolescents become better leaders of the future. In turn they benefit society as a whole by creating a culture of understanding and willingness to work for an improved future (Network, 2012).In downtown Ogden a building has been proposed as a gathering place for youth between the ages of 14 and 18. The name of the building would be The Northern Utah Youth Center. The proposed design of the building has been created to accommodate a unique style of learning. It will provide a creative environment where youth are allowed to explore and experiment through the application of hands on learning. Utilizing the use of appropriate lighting, color and architectural design will allow for the youth to feel more at ease, creative, and constructive (Saxton, 2012). Within the two floors of the building, multipurpose rooms may be divided with partitions to maximize the use of space.

Kinsley Oates, Weber State University Interior Design Research shows that athletics help pave the wave for student to pay for college and obtain an education. (Proposition 48, N.C.A.A 2010) Proposition 48 supports this cause by focusing on the output of graduating students, rather than the input of entrance standards. The N.C.A.A studies show, “The persistence of low-achieving students in college have suggested that participation in athletics is frequently the catalyst for student who have not performed well in high school to study more diligently and, ultimately, to graduate.” Steve Kendall wrote that for many at-risk students, athletics is the only reason they go to school. He states, “These at-risk students who have no other reason to attend school other than athletics benefit from this policy. They are in classes and participating in the activities and exercises happening in the classrooms.” Jerry Tarkanian a coach at UNLV defends his stance on trying to help underprivileged players deserve a shot at straightening out their lives. The Maple Leaf Training Center located in Spanish Fork Utah, will provide at-risk student who attend high school a privilege to obtain scholarships and a chance of going to a college or university. Students who live in poverty and low income home do not have an option to get into colleges or universities. This 23,000 square foot facility will help 1st generations college students train and obtain scholarships, both academic and athletic for them to continue on to a college or university to pursue their future.

Kristina Hess, Weber State University Interior Design Technology According to USA Today & Thompson Healthcare Center for Health Statistics and Bureau of Census Data, Utah is has the highest rate of depression in the nation. Research shows that girls become more likely to experience depression than boys in adolescents (NIMH)Prominence Residential Depression Treatment Center for adolescent girls will house the staff needed to perform program duties and will house the in-patient care residents. The facility requires an accredited high school, patient and staff housing, food preparation area, a cafeteria, a nursing station, therapy rooms, admin room, a homework room, and a free time room. Daylighting strategies will be needed for the treatment process. The program at Prominence will incorporate the research from Nedley (2011). The study concluded that part of depression is caused from not getting enough vitamin D that the sun produces. In addition, Prominence wants to promote safety and security for patients and as well as provide a family atmosphere. An appropriate color scheme to facilitate healing as well as accessibility will need to be taken into consideration and planned for accordingly.

Jessica Corey, Weber State University Interior Design Research has shown that senior citizens, due to the aging eye, need special accommodations in their daily activities and living (Moller, 2008). “The purpose of [the International Building] codes is to establish the minimum requirements to safeguard the public health, safety and general welfare through structural strength, means of egress facilities, stability, sanitation, adequate light and ventilation, energy conservation, and safety to life and property from fire and other hazards attributed to the built environment and to provide safety to fire fighters and emergency responders during emergency operations” (IBC 101.3 Intent). The independent senior living facility, Riley Court is being renovated to cater to the elderly. In addition to implementing universal design concepts, research on the aging eye, community-dwelling for elders, and functional limitations will enhance their ability to be independent. Moller’s research showed that visual impairment is one of the top four reasons for a loss of independence among seniors. The study suggested that lighting, color, and accessories have a high priority of focus when designing for older individuals. Riley Court, a 15,000 square foot independent senior living facility, located in Bountiful, Utah will feature a fully accessible facility and finishes that reflect the research from Moller’s study. In addition, adequate lighting will be provided as well as a home-like atmosphere for residents.

Brook Owen, Dixie State University Theatre My theory is that theatre can portray emotion and convey a story without verbal communication. As an actor, I struggled to portray emotion while using a memorized script. As I worked through my theatrical training, I was introduced to exercises that took away language. I found artistic freedom in these exercises and formulated a research project to understand what would happen if actors were given freedom from language completely. This research is founded in the works of artists such as mime John Weaver and absurdist Samuel Beckett. One of the most prominent movement artists of our time is Anne Bogart. Her movement technique, called Viewpoints, focuses on the physical aspects of portraying emotion and kinesthetic response. This is where my physical research started. In rehearsal, actors experiment with Bogart’s viewpoints, while responding to different styles of music. Then I begin to move away from Bogart’s research. While allowing them to maintain their own organic choices, I give my actors more specific acting objectives with which to work. For example, “Imagine that your character wants to purpose.” Once completed, the actors talk to me about how the exercise expanded their physical toolbox. One comment from an actor symbolizes the heart of this research. “When the music starts, you think of an emotion, and then you start responding to that emotion. That’s when the character starts to form. And the next thing you know, you have a little story around it.” Repetition of this process will culminate in a narrative movement piece.

Jennifer Sumsion, Utah Valley University Art I am influenced by natural elements, the combination of shapes, colors and textures are what interest me. The commonplace, banal and unnoticed aspects of nature draws my focus and inspires me capture images to my vision and transform them onto paper and canvas. The constant change in rocks, leaves, skies, trees and water continue to focus my attention and are reflected back into my images. The balance of lines, colors and tones adds patterns energy and new life when mixed together. Nature can look foreign when viewed close-up, intensifying the smallest detail. Unnatural influence on the environment has added a unique aspect to nature. It can create extraordinary patterns and encourage new images that are beautiful in themselves. I enjoy the way leaves fall on a sidewalk, the patterns of melted water and salt on the road after a snowstorm, the ice crystals that form on tree limbs when pollution levels are high and the light and shapes reflected in shoveled snow when it begins to melt. I use cool and warm colors together to create a bounce off of each other. I enjoy using oil paints, ink charcoal, acrylic, and nupastels in my work.

Thomas Skousen, Dixie State University Art Concordia apostolorum, the union of apostles, is found in literature, art, and even the topography of Rome. Rome is unique in the fact that it unites Peter and Paul. Early Christians revered these saints and dedicated two of the most important churches in the city to them. Their deaths in Rome were a crucial factor in identifying Rome as the principal capital of Christendom. As Christianity spread and was accepted throughout the empire, different Christian centers arose, aside from Jerusalem and Rome. In order to maintain its place at the top tier of the Christian hierarchy, the Roman Popes used the idea of concordia apostolorum to not only speak to Roman citizens, but also to pilgrims who visited the city. The use of concordia apostolorum extended into the ninth century with Pope Paschal I’s (817-824) mosaics at Santa Prassede. These have historically been categorized into the Carolingian Renaissance. However, Paschal and earlier popes were trying to create a uniquely Roman Renaissance, and Peter and Paul’s place in art is crucial to their propaganda. The apse mosaic in Santa Prassede employs concordia apostolorum to promote the primacy of Rome. Louis the Pious inherited the empire from his father Charlemagne and surrounded himself with bishops and scholars who questioned the authority of the pope, thus igniting a struggle between the pope and the Carolingians. This paper will show that Paschal I commissioned art that emphasized his role in carrying out the ministerial work of Peter and Paul. In art and in life, Paschal sought to become not only the principal figure in Christianity, a living apostle, but also a chief player in Europe’s political structure.

Krista Brown, Weber State University Interior Design Research has shown that through January 2007, the wounded-to-fatality counts of Operation Iraqi Freedom is higher (about 7.6) than during earlier U.S. military conflicts, such as the ratio of 5.2 for Vietnam (Goldberg, 2010). This means that more soldiers are dying more from hostile combat rather than sickness or non-battle injuries. The Salt Lake area is not currently set up to accommodate the needs of these returning military personnel who have been inflicted with a war injury. Rooms are not adequate and not all necessary areas such as burn rehabilitation are addressed. The government has allowed for a veteran support home to be put into an existing building in Salt Lake City, UT. The objective of the veteran’s support home, “Hope Against Hope,” is to create a facility approximately 15,000 square feet that creates an area for veterans to heal and adapt to their new life style. Currently there is a lack of facilities in Utah that can fulfill all of the needs the “Hope Against Hope Veteran Support Home,” plans to accommodate. This support home will be located in Salt Lake City near the University of Utah hospital. This area was chosen because of the close proximity to the airport, the local medical support and emergency services, as well as the beauty of the surrounding area. Among the needs for the “Hope Against Hope,” center include future expansion, comfort, and should reflect universal design principles. In addition day lighting principles will be a focus. Research has shown that people in institutional areas don’t receive adequate exposure to natural light needed to synchronize sleeping patterns (Brawley, 2009). An advantage of the current location of the center is the close proximity to the Wasatch Mountain Range which provides spectacular views. This advantage will be used to promote healing as well as giving patients a sense of night and day in a home like setting. Color, common rooms, and a flowing floor plan will also provide a new life and hope for injured veterans as they recover from injuries sustained in military service.

Kyra Marie Bell, Weber State University Interior Design The negative impacts that tourists can have on the environment is a major reason that so many pristine natural habitats are off limits to travelers. With so many tourists around the world, the effects of carbon emissions from transportation, excessive waste, and harm to delicate ecosystems, these restricted areas seem to be growing (Center for Ecotourism and Sustainable Development (CESD), 2009) As a result, ecotourism has started to gain popularity, as it focuses on minimizing ecological and socio-cultural impacts (TIES, 2012). With the emergence of LEED certification, builders and designers are now provided with a way to implement green building design throughout the entire building process (USGBC, 2011). This makes it possible to not only construct a hotel built in sustainable ways, but to continually have a lower impact on the environment and educate people on ways they can lessen their own footprint. However, less than 100 hotels world-wide have achieved LEED certification, and as of 2010 there is only one such hotel in Utah (HKS, 2011). In Southern Utah, where many of the states national parks are located, lodging that meets the needs of ecotourism by limiting its impact on the environment is nearly non-existent. In order to visit the beautiful, undisturbed environments available in these regions, tourists need a place where they can stay that they know focuses on sustainability and limited impact on the environment as much as the tourists do. Having an ecotourism hotel in Southern Utah would encourage “tourism that seeks to minimize ecological and socio-cultural impacts while providing economic benefits to local communities” (TIES, 2012).In order to meet these needs, The Hotel Viridi will be built as a 15,000 square foot eco-tourism hotel in Southern Utah that meets all the LEED certification requirements as well as the 12 Aims of Sustainable Tourism (Center for Ecotourism and Sustainable Development (CESD), 2009). These needs will be met through the use of an adaptive re-use building, in which the hotel will incorporate four different aspects of design; hospitality design as found in all public areas of the hotel, a residential area for hotel guests to stay, healthcare design in the form of an onsite gym, and commercial design where the offices and lecture hall are located.

Sarah Breinholt, Weber State University Interior Design Spiriti Forti Rebuild and Recovery Center is a facility that heals the psychological and body issues for individuals with eating disorders. Research has shown that long-term stay care facilities should contain a “home-like” atmosphere that reflects the site’s surroundings. In a study by Schneider (2008) explains the importance for the patient to feel comfortable and relaxed in order to achieve maximum recovery. In addition, a study by Kaya (2009) explores the effect that color has on individual’s emotions and health. A study that was completed on a group of individuals of all ages and all nationalities shows that overall; people have very similar reactions to the same colors in spite of age or race. The colors blue and green have been recognized to reduce anxiety and promote calmness and well-being. Because of this reason, this color palette will be implemented in the design of this recovery center. A former historic train station in St. George, Utah has been acquired by Spiriti Forti Rebuild and Recovery Center to be renovated to accommodate a getaway for patients to escape the world and rebuild their body image and self-esteem. Among the features of the care center will cafeteria/kitchen that focuses on education and nutrition, rooms for long-term stay, as well as spaces for multiple activities for individual and group building exercises. This facility should become a place that provides all the necessary components for patients to make a full recovery of their psychological and image disorders.

Hilary Wolfley, Brigham Young University Dance The purpose of this project is to enhance the caliber and reputation of ballet in higher education-specifically contemporary ballet at BYU-while strengthening my own choreographic abilities under the guidance and coaching of my mentor, Shani Robison, Associate Professor. I have choreographed an original contemporary ballet entitled “Transition” that explores the ways in which we react to the challenges of change in our lives. Through exploring this theme, creating innovative movement, and rehearsing with talented dancers, I am working closely with my mentor to fulfill UCUR’s mission to creatively contribute to the discipline of contemporary ballet. I recently completed this project as the culmination of my undergraduate work at BYU as a dance major. This is the link to my project as performed last week at the BYU Ballet Showcase: http://youtu.be/j1t0MPcLUyw (DVD available upon request). The BYU Ballet Program has selected me as the only ballet student from BYU this year to represent undergraduate student creative work by presenting my project at the American College Dance Festival Northwest Region at Southern Utah University March 11-15, 2013 (ACDF). During this festival, my piece will be viewed by collegiate dance students and educators from across the country and adjudicated by internationally renowned experts in the dance field.

Brittany Brown, Weber State University Interior Design According to the article Contributions of Built Environment 68% of the adult population is considered obese. (Rahman, 2011) The article also states that childhood obesity is on a steady rise. The research provides evidence that obesity shortens Americans life expectancy by 2 to 5 years on average. The study by Rahman recommends that adults engage in at least 150 minutes of moderate-intensity aerobic activity weekly and at least 60 minutes every day. The Spencer Weight Loss Retreat is a 18,000 square foot facility located in Meridian, Mississippi. The weight loss retreat will provide weight loss training and medical attention for those residents of Meridian who are considered obese and want treatment to gain back their lives. The weight loss center will provide each patient with a personal trainer who will guide in their weight loss. The facility will provide the patients access to their gym where they can use treadmills, bikes, weights, outdoor routines, and other activities to meet the 150 minute workouts a week. The Spencer Weight Loss Retreat will provide a classroom to educate the patients in nutrition and other life skills.

Machaela Burt, Utah State University Theatre Arts This research study explores the efficacy of the “Living Literature Project”, a program that teaches traditional English curriculum in high school classrooms using theatre-based strategies to enhance understanding of Shakespearean texts. The study was piloted with two control classes and two intervention classes in 2012 with strategies such as viewing performances by experienced actors during class and paraphrasing texts into modern speech to assess the impact on learning through the use of teacher-administered pre and post project surveys assessing student attitudes towards Shakespeare as well as content quizzes. The results of the pilot study suggested that students who participated in the project achieved higher quiz scores, but their attitudes about Shakespeare were not changed. The pilot study informed further developments of the teaching strategies and led to further curriculum development. The project is currently in session for the 12-13 school year. The study is being expanded to include a larger number of classes that will also assess teacher satisfaction with the academic progress made by the students involved. The results will be assessed through revised surveys and quizzes as well as focus groups with the students. Results are anticipated in April 2013. The pilot study suggested that arts integration and the building of cross-curricular relationships have a positive effect on student learning. The current study hopes to reinforce these results with more accurate assessments and to see increased topical interest, measured through focus groups.

Paul Chidsey, Brigham Young University Chemistry and Biochemistry It has been reported that an estimated 11% of women in the population have undiagnosed endometriosis, emphasizing the need for early detection tests and treatment options. Diagnosis is typically determined through an analysis of symptoms, including painful menstrual cycles, pain in the lower abdomen, and prolonged menstrual cramping. Diagnosis is further confirmed through invasive procedures such as transvaginal ultrasound and pelvic laparoscopy. Serum proteomic studies in which small biomolecules and peptides are analyzed for biological significance in endometriosis cases and controls can lead to the discovery of novel methods whereby the disease is detected and eventually treated earlier in development without the need of invasive procedures. Comparative analysis of cases and controls through mass spectroscopy has led to the discovery of novel biomarkers capable of correctly identifying individuals with endometriosis. Further pursuing this study will allow for a greater understanding of the genesis of the disease, eventually uncovering the mechanism whereby endometriosis develops.

Devon Blake, Brigham Young University Chemistry and Biochemistry G proteins play a vital role in cellular signaling. It has recently been shown that the nascent G polypeptide requires the assistance of phosducin-like protein 1 (PhLP1) for proper folding and formation of the G beta gamma dimer. This mechanism is derived from cell culture experiments and structural data, but until now had yet to be tested in vivo. We tested PhLP1 function in vivo using retinal rod photoreceptor-specific PhLP1 conditional knockout mice. Electroretinogram analyses of these mice showed a dramatic decrease in light sensitivity of rod photoreceptors. Consistent with this finding, the expression of all subunits of the photoreceptor G protein was reduced by 80%. This decrease was reflected in a similar decrease in the amount of G beta gamma dimers. All of these in vivo results are consistent with the hypothesis that PhLP1 is required for G beta gamma assembly and G protein signaling.

Jennifer Campbell, Utah State University Psychology Eating disorders are pervasive mental illnesses that overwhelm the lives of individuals who struggle with them. For individuals with anorexia nervosa or bulimia nervosa who do not respond to other treatments, Acceptance and Commitment Therapy has the potential to be effective. This presentation looks to orient researchers to Acceptance and Commitment Therapy while supplying a potentially useful treatment option for those who struggle with clinical anorexia nervosa or bulimia nervosa. The current literature comes together to support the effectiveness of Acceptance and Commitment Therapy for the treatment of eating disorders, specifically anorexia. This presentation focuses on the symptomatology and physical effects of anorexia and bulimia, as well as core principles and processes of Acceptance and Commitment Therapy. Future directions regarding the effectiveness of Acceptance and Commitment Therapy can be broadened to include adolescents as well as other types of eating disorders, such as binge eating disorder and eating disorders not otherwise specified.

Lauren Miller, Utah State University Psychology Affective disorders such as depression, phobias, schizophrenia, and post-traumatic stress disorder impairs the ability to time in the seconds-to-minutes range, i.e., interval timing. We investigated the effect of chronic administration of selective serotonin reuptake inhibitor fluoxetine (FLX) when anxiety-inducing task-irrelevant distracters are presented during an interval timing task. Given that some anti-depressants have beneficial effects on attention and working memory, e.g., decreasing emotional response to negative events, we hypothesized that FLX would decrease activation of amygdala and increase activation of prefrontal cortex. Our results revealed differential activation of amygdala and prefrontal cortex in FLX and vehicle treated rats corresponding to the expected changes in behavior. Results are discussed in relation to the brain circuits involved in interval timing and emotional processing, and the pharmacological management of affective disorders.

Dani Willis, Utah State University Political Science In this era of increasing complex electric utility corporate restructurings, prudence review is an important analytical tool that should be applied by state regulatory commissions in an informed and reasonable manner to address and balance risk sharing between electric utility investors and utility ratepayers. The payer examines the legal and economic considerations concerning the development and application of the analytical tool of prudence review by state regulatory commissions concerning the revenue requirement regulation of electric utilities.

Yoon Lee, Utah State University Family, Consumer, and Human Development Drug abuse in America is a major problem that has been well documented throughout history. Marijuana use has increased among most age levels and is the most abused illicit drug in America. Cocaine use has also increased over the past decade. Possibly the most alarming trend is the fact that hospital visits due to drug abuse of any kind are dramatically increasing each year. Using data from the National Survey on Drug Use and Health (2010), this study explored to what extent adolescents and young adults were involved with Marijuana or Cocaine abuse and to investigate factors associated with their use of such illicit drugs. For the data analyses, the total sample included 37,926 individuals between the ages of 12 and 25; the sub-sample of this study consisted of Adolescents between the ages of 12 and 17 (n=18,622) and young adults between the ages of 18-25 (n=19,304). The descriptive statistics suggested that among the study sample, 35.3 percent reported they ever used marijuana, while 7.5 percent reported they ever used cocaine. The results of logistic regression analyses show that all else being equal, age, health, gender, race, county size, and illicit drug addiction are statistically significant in predicting the likelihood of reporting marijuana experience among young adults between ages of 12-25. Similarly, the results of logistic regression analyses show that all else being equal, age, health, gender, education, race, county size, and illicit drug addiction are statistically significant in predicting the likelihood of reporting marijuana experience among young adults between ages of 12-25.

Noreen Barnes, Weber State University Political Science Many women in Guatemala suffer poverty and repression their entire lives. This situation is not unique to countries in Central America, but what is unique is the level of violence that is perpetrated in Guatemala compared with neighboring countries, the lack of engagement by law enforcement, and the complicity of the media. The Guatemalan civil war helped to create an atmosphere riddled with violence and alcohol. There is only a two percent conviction rate for murder. The majority of media outlets report on Femicide as if it were the woman’s fault she was killed; they portray her as a prostitute when there is no evidence to support the conclusion. In 2000 there were 213 femicides in Guatemala, by 2009 that number had jumped to 708 (Guatemalan Human Rights Commission 2010). My research has come from peer reviewed articles in both English and Spanish, Guatemalan government figures, personal experiences and international sources such as the World Health Organization. How do these details combine to create the perfect storm of increasing Femicide in Guatemala, and what can be done to help stop this tide of violence? There are women who have taken steps to improve their lives despite the many challenges they face. Micro-credit, small loans given to women to help them start or expand a business, have helped women who have a desire to flee abusive situations by giving them self-esteem as well as the financial means to accomplish their desires. There is a movement amongst women to convince their husbands to join Evangelical Christian churches that do not permit drinking in an effort to control rampant alcoholism. It will take time to alter the prevailing attitudes of machismo, prejudice, and lack of tolerance that threatens to drown the wonderful of Guatemala, but it can be done.

Kevin Lawanto, Utah State University Psychology Mice are excellent models for studying aggressive behaviors and the neural circuits underlying aggression. They identify their conspecifics through olfactory communication within the animal group (emission scent marking and detection of volatile and nonvolatile chemicals, such as pheromones). Anomalies in the perception and processing of olfactory cues may induce abnormal social behavior, anxiety or aggression. We performed a behavioral assessment of male NrCAM knockout mice and wild-type littermates. We found that NrCAM-deficient male mice exhibit increased aggression towards unknown conspecifics. Using cFos immunostaining, we revealed differences in neuronal activation between NrCAM knockout mice and wildtype littermates in a circuit relevant to processing of olfactory cues and male-specific behaviors (olfactory bulb, amygdala, bed nucleus of the stria terminalis and hypothalamus). These differences may be the result of misrepresentation of olfactory cues due to abnormal neuronal connectivity in the olfactory system. Our studies may be relevant to pathophysiological mechanisms responsible for abnormal social behaviors, aggression and anxiety.

Elizabeth Payne, Utah State University Anthropology This paper is an exploratory ethnographic research project designed to collect stories of health care experiences of childbirth in Cache Valley, Utah. By interviewing women who have given birth in Cache Valley, key themes have been identified as being significant to the childbirth community, these are; the Biomedicalization of childbirth; Tensions between the biomedical and holistic out-of-hospital approaches to births; Out-of-control pitocin use; and the Beliefs and Attitudes associated with giving birth. I compare the results with my own experiences as well as in the literature. The discussions raises issues of concern and an applied suggested course of action is offered to policy makers.

Eric Hastings, Utah State University Psychology Does building a new school facility change the quality of the school learning environment? If so, how enduring are these effects? Research shows some correlation between the physical environment of a school and student outcomes to. However, research fails to demonstrate that drastic changes to the environment through reconstruction influence those same outcomes. To investigate this relationship a group of newly built/reconstructed schools was identified and looked at longitudinally to measure the quality of the school’s learning environment two years before construction and four years after construction. To measure the school’s learning environment this research used the Indicators of School Quality survey (ISQ); a comprehensive survey system for school administrators to evaluate and monitor school improvement and accreditation efforts which provides information on the status of the schools learning environment, year to year progress and details about the conditions for learning produced in the classrooms. ISQ does this by measuring parent, teacher, and student perceptions of things such as parent support, teacher excellence, student commitment, school leadership, instructional quality, resource management, and school safety. In addition to the impact of school construction on a school’s learning environment, this analysis was extended to student attendance, safety, and student academic achievement. Data collected to this point supports the argument that school construction only has short term effects on a school’s learning environment, but no long lasting effect. Instead of investing in new facilities, schools and districts would be wise to first consider giving more attention to maintaining student and teacher relationships.

Alysha Waters, Utah State University Psychology Emotional distracters impair cognitive function. Emotional processing is dysregulated in affective disorders such as depression, phobias, schizophrenia, and post-traumatic stress disorder. Among the processes impaired by emotional distracters, and whose dysregulation is documented in affective disorders, is the ability to time in the seconds-to-minutes range, i.e., interval timing. Presentation of task-irrelevant distracters during a timing task results in a delay in responding suggesting a failure to maintain subjective time in working memory, possibly due to attentional and working memory resources being diverted away from timing, as proposed by the Relative Time-Sharing (RTS) model. We investigated the role of the prelimbic cortex (PrL) in the detrimental effect of anxiety-inducing task-irrelevant distracters on the cognitive ability to keep track of time, using local infusions of selective serotonin reuptake inhibitor fluoxetine (FLX). Given that some anti-depressants have beneficial effects on attention and working memory, e.g., decreasing emotional response to negative events, we hypothesized that FLX would improve maintenance of information in working memory in trials with distracters, resulting in a decrease of the disruptive effect of emotional events on the timekeeping abilities. Our results revealed a dissociation of the effects of FLX infusion in PrL between interval timing and resource allocation, and between neutral and anxiety-inducing distraction. FLX was effective only during trials with distracters, but not during trials without distracters. FLX reduced the detrimental effect of the distracters only when the distracters were anxiety-inducing, but not when they were neutral. Results are discussed in relation to the brain circuits involved in RTS of resources, and the pharmacological management of affective disorders.

Ariel Hargrave, Weber State University Psychology A review of the literature surrounding mental health literacy has suggested that there are many misconceptions about those with a mental illness. These misconceptions effect help-seeking, treatment, mental health policies, early intervention and social support. The National Alliance on Mental Illness (NAMI) offers a peer-to-peer taught class called Building Recovery of Individual Dreams and Goals through Education and Support (BRIDGES). This class addresses these misconceptions and aims to educate those suffering with mental illness on how to self-advocate. Research suggests that a peer-to-peer approach has been found useful in a consumer’s recovery process. Support and education are crucial in society’s understanding of mental illness and aids in their ability to strive towards a stigma free environment. The objective of this study is to measure the effectiveness of this class by conducting a pre and post assessment at the beginning of the class before material is presented and at the end of the class. A population of approximately 100 participants over the age of 18 diagnosed with a mental illness will be used. The assessment includes eleven total questions that identify key factors to recovery and mental health literacy. A five point likert scale will be used to measure participant’s responses. Data will be collected starting in January of 2013 and will be completed in March of 2013. Data will then be analyzed using a T-test in SPSS.

Zachary Cook, Utah Valley University Behavioral Science A Trend analysis of counseling visits to Utah Valley Universities (UVU) student health center was carried out between the months of January to October of 2012. During this time intake forms from students were examined in alphabetical order by HIPPA trained researchers and assessed for the frequency of the client’s visits along with their chief complaint as determined by the therapists. High frequencies of complaints such as depression, anxiety, and educational issues were reported from students attending the university in past studies beginning in 1999 at UVU’s health center. Researchers at Kansas State University used an instrument known as the Case Descriptor List to measure a therapist’s assessment of a client’s problems based on nineteen categories including items such as depression, anxiety, and educational/vocational issues (Benton, Robertson, Tseng, Newton, & Benton, 2003, p. 69). The basis of the present study was formulated by collapsing the nineteen categories into fourteen constructs for simplicity in order to determine the trend found between the years of 2006 to 2011. During this time 1,974 individuals obtained counseling services from UVU’s student health center. The research found that 56% of clients sought therapy for depression, 38.1% for anxiety, and 39.9% for educational assistance based on the stated categories. An increase in issues such as depression and anxiety has demonstrated the need for an increase in the number of trained therapists as it relates to the complexity of issues and co-morbidity. It has also shown the need for improved intake procedures, focusing on accurate diagnosis which the counseling center has recently adopted.

Karen Yu, University of Utah Psychology Objective

Dallin Webb, Utah State University Sociology, Social Work, and Anthropology Recent rediscovery of an ancient Fremont irrigation system in central Utah presents the opportunity to model the economics of Fremont irrigation agriculture. A significant cost of irrigation farming is the construction of a ditch to bring water from a natural source to the fields. We use an experimental approach to investigate the costs of ditch construction. Mountain mahogany digging sticks were employed to construct ditches under different sediment conditions, as well as a stream diversion into a ditch take-out. The experiments reveal a range of costs incurred for constructing different elements of the system.

Heather Sheffer, Utah State University Family Consumer and Human Development Background:

Austin LaBau, Utah State University History and Sociology At the beginning of the 19th century, there was only one public insane asylum in the United States. Together, this facility and a handful of private hospitals housed only a few hundred patients. By 1890, more than 74,000 Americans lived in mental institutions. A wealth of literature exists on the rise of the American insane asylum during this period; the evolution of modern psychiatry; and the philosophical, political, social, and ethical implications of the two. But what the literature lacks is a perspective on the rise of the asylum that recognizes its place in the developing urban environment. This project addresses that shortcoming by exploring a small group of institutions within the context of a single urban center; New York. In 1890, one-in-twenty-five Americans lived in what would soon become New York City’s five boroughs, alongside nearly one-in-ten of the country’s institutionalized insane. Upon opening, NYC’s massive insane asylums became a source of pride for city’s elites. Far from being hidden away, most of the asylums were built on islands in the East River—at the time, one of the busiest waterways in the world. Nestled between Brooklyn and Manhattan, the imposing structures and their residents lived in clear view of thousands of daily commuters, and inspired numerous poems, novels, and songs. However, it was not their largess that attracted international visitors like Charles Dickens and Alexis de Tocqueville, but the unique circumstances in which they operated. Throughout the 19th century, the intimate nature of NYC, where masses of impoverished immigrants lived only blocks from some of the richest and most powerful men in the world, helped make the city the site of violent class warfare, as well as a testing ground for social reform. Insane asylums were only a portion of NYC’s sprawling public welfare system, consisting of nearly a hundred public and private charitable institutions inn Manhattan alone. To explain how the insane asylum affected New York City, I examine essays, and photographs written and taken by doctors, patients, reporters, and reformers illustrate the significance of the insane asylum on New York City life.

Amanda Snow, Utah State University Psychology Past studies investigating attention have found that exposure to natural scenes have a restorative effect on attention in adults, allowing for the occurrence of effortless, involuntary attention. This is in contrast to exposure to urban scenes which do not show the same restorative effect on attention (Berto et al., 2005, 2008). The present study investigates the potentially restorative effects on childhood attention of exposure to natural scenes. In this study, 58 children ages 4 to 11 participated in a task which was attentionally taxing. Next, they were instructed to attend to pictures belonging to one of three conditions: “high fascination” (natural scenes), “low fascination” (urban scenes), or a control group (geometric shapes). Finally, the participants performed the initial attentionally taxing task once again. While accuracy remained constant across conditions, children demonstrated a greater decreased reaction time when exposed to high fascination natural scenes as opposed to low fascination urban scenes or the geometric shapes of the control group. Between the pre and post tests, mean differences of 37.7 milliseconds for the natural condition, 24.4 milliseconds for the urban condition, and 22.7 milliseconds for the control group was found. This suggests that exposure to high fascination natural scenes has a restorative effect on attention in children as it does in adults. This finding is important because it provides a mechanism by which the attentional capacities of children may be improved.