2013 Abstracts

Lauren Johnson, Weber State University Microbiology Bacteriophages in aquatic environments play a significant role in bacteria population control, as well as recycling nutrients. The bacterial genus Halomonas is commonly found in the Great Salt Lake (GSL), but very little is known concerning its population dynamics. This euryhalophilic genus is highly versatile concerning its ability to grow in a wide range of substrates and environmental conditions including salt concentration. To better understand GSL microbial ecology, seven strains of Halomonas were isolated from the GSL and identified using 16S rRNA. Samples of South Arm GSL water were filtered twice through a 0.2 m filter, and tested against these Halomonas strains using soft agar overlays to detect Halomonas phage. Three strains exhibited plaque formation indicating the presence of phage. Halomonas phage isolates produced very small plaques, sometimes barely visible. Individual phages were isolated by vortexing agar plugs taken from single plaques in sterile saline then filtering through a 0.2 m filter. From host range streak plates, a single phage isolate (LJ17) appears to infect 4 closely related Halomonas strains. Electron micrographs of LJ17 phage indicate it has a small icosahedral head and perhaps a very short tail. There also appears to be a satellite phage that may be associated with LJ17. There are no reports of Halomonas phage isolated from the Great Salt Lake (GSL), although there are phages found for marine Halomonas strains. Successful isolation and characterization of novel GSL Halomonas phage, besides being critical for development of host/phage models, will also allow studies of GSL microbial ecology.

Graham Doherty, Westminster College Biology The Great Salt Lake is home to Artemia Franciscana, a species otherwise known as brine shrimp. These halophiles are able to live in extreme environments that have higher than average salt concentrations. Brine shrimp live their entire life cycles in the Great Salt Lake and can be found in both the north and south arm of the lake. Currently, the genetic information regarding the brine shrimp populations at different locations in the lake is underdeveloped. The Artemia populations live in different microenvironments throughout the lake with different physical characteristics and barriers between one another. The physical environment also affects the salt concentration in each microenvironment. Other studies have shown that the increased salinity of an environment accelerates the rate of change in the mitochondrial genome. We feel that different salinity levels in each microenvironment will create different amounts of genetic variation. Our goal is to determine if the distribution of genetic variation is different at different sites in the Great Salt Lake Artemia population.

Mark Tingey, Utah Valley University Biology The phylogenetic relationship of Ephemeroptera (mayflies), Odonata (dragonflies) and Neoptera (remaining winged insects) has been a problematic isse in insect evolution and systematics. Resolving their relationships is a critical step toward understanding insect diversification and the evolution of flight. Three hypotheses are evaluated so as to determine the phylogenetic placement of these three orders of insects: 1) Ephemeroptera sister to Odonata + Neoptera; 2) Monophyletic Paleoptera (Ephemeroptera + Odonata); and 3) Odonata sister to Ephemeroptera + Neoptera. Data from more than 260 taxa were collected from Genbank and assembled into a supermatrix representing 6 different molecular markers. Each of the genes were aligned and phylogenetic analyses were carried out utilizing a number of different methods including Bayesian, maximum likelihood, and parsimony frameworks in order to elucidate the relationships of these insect groups. The large number of taxa proved to be a daunting task, but provided new insights into the support for the different hypotheses. The implications for the evolution of flight were examined in light of the generated phylogenies.

Jeff Collins, Westminster College Biology The Great Salt Lake (GSL) has some of the highest mercury concentrations ever measured in surface waters. The accumulation of high levels of mercury, particularly its more toxic and readily biomagnified form, methylmercury, has been recorded in many species that inhabit or feed directly in the GSL, including waterfowl. However, no studies at the GSL, and very few studies elsewhere, have investigated the transfer of mercury from aquatic ecosystems to terrestrial ecosystems. We hypothesized that brine flies are able to accumulate mercury during their larval stages in the lake, then transfer this mercury to adjacent terrestrial ecosystems when they become flying adults. Concentrations of total mercury (HgT) and methylmercury (MeHg) were measured in samples of surface water and brine flies (larvae, pupae, and adults) collected once each month between February and July at Antelope Island, in the GSL. Samples were collected from two distinct sites: one along Gilbert Bay on the west side of the Island, and the other along Farmington Bay on the east. On average, HgT concentrations are greater in water samples from Farmington Bay (19.3 ± 9.0 ng/L unfiltered; 13.5 ± 10.1 ng/L filtered) compared to Gilbert Bay (8.5 ± 7.5 ng/L unfiltered; 9.2 ± 9.6 ng/L filtered). MeHg and HgT levels in brine flies displayed the opposite trend, with higher levels at Gilbert Bay (567 ± 123 ppb HgT; 425 ± 12 ppb MeHg) than at Farmington Bay (270 ± 60 ppb HgT; 208 ± 35 ppb MeHg). Potential explanations for the trends observed will be discussed.

Kristie Williamson, Weber State University Athletic Training Context: Cranial Nerve V (CN V; Trigeminal nerve) is responsible for facial sensation. CN V has three separate branches which include ophthalmic, maxillary and mandibular. The ophthalmic nerve (V1) carries sensory information from the forehead; the maxillary nerve (V2) carries information from the cheek; and the mandibular nerve (V3) carries information from the chin. It is important to test all three areas of cranial nerve V to accurately assess full nerve function. Previous research has indicated that pressure threshold is not affected by age, however, normative values for two-point discrimination for CN V have not yet been established and may prove useful in concussion evaluation. Objective: Initial investigation aimed at determining gender-specific normative values for CN V two-point discrimination. Design: Prospective repeated-measures design. Setting: This study was performed in the athletic training facilities on the campus of a large Division I institution. Patients or Other Participants: Convenience sample of 106 healthy students enrolled at our institution (43 females, average age: 23.2; 63 males, average age: 22.1). Participants had no history of concussion within the last year, no facial scaring or plastic surgery and not a current smoker. Interventions: Measurement was taken using a two-point discriminator (Disk-Criminator) on the mid-forehead, mid-cheek, and mid-chin. Participants closed their eyes while each measurement was taken. Light pressure was applied (force equal to approximately 10-15 grams to produce blanching of the skin). Measurements were taken three times on each of three facial locations, sequentially. The smallest number in millimeters (mm) to correctly discriminate one/two points was recorded. The two pressure points were applied at exactly the same time. Main Outcome Measure: Discrimination score for each test location (mid-forehead, mid-cheek, mid-chin). Nested average was calculated within subjects for each test location; average was calculated between subjects for each test location. One-way between-subjects ANOVAs were conducted to evaluate potential differences in gender for each test location. Results: Between-subjects average for mid-forehead was 7.8mm (+/2.9), for mid-cheek was 10.4mm (+/2.6), and for mid-chin was 5.9mm (+/1.9). There was a significant effect for gender for cheek normative value (p<0.01); average discrimination score for males was 11mm, average for female was 9.7mm.

Adam Olson, Brigham Young University Plant and Wildlife Sciences Forests systems of the Central Rocky Mountains rely on an intricate balance of natural disturbance cycles in order to develop properly. Forest fires are one such disturbance, however, certain fire characteristics, particularly fire severity, can vary widely across forest landscapes. In our study, we examined the influence of fire severity on aspen regeneration as well as aspen defense against wildlife and livestock browsing. Our results indicate that high or moderate burn severity is more favorable to aspen regeneration and survival. These areas of severe burn result in a higher density of aspen suckers, more vertical and lateral growth, greater chemical defense concentrations, and less browse damage than the neighboring plots of low or no burn. This data suggests that fire severity should be taken into account when considering plant regeneration and susceptibility to browse damage in burned landscapes.

Matthew Whited, Brigham Young University Biochemistry Several lines of evidence suggest that protein lysine acetylation pathways are deregulated in cancer (1). Moreover, deacetylase inhibitors are emerging as important anti-tumor therapeutics, suggesting that the forced reprogramming of protein-lysine acetylation is toxic to tumor cells. In this study we show that Sirt1, an NAD+-dependent Sirtuin deacetylase that promotes cancer cell survival, is aberrantly mislocalized to the cytoplasm of breast tumor cells. Moreover, the depletion of cytosolic Sirt1 by siRNA sensitizes breast tumor cells to paclitaxel-induced death. Previously, we developed a biotin-switch proteomics approach to identify cytosolic Sirt1 substrates (2). This approach yielded a variety of substrates with roles in metabolism, survival, and oxidative stress signaling. Our current work focuses on three of the proteins identified as Sirt1 substrates: SOD1, DJ-1, and 14-3-3z. SOD1 and DJ-1 both suppress oxidative stress-induced death, and high levels of 14-3-3z expression suppress chemotherapy-induced apoptosis and correlate with negative patient outcomes in breast cancer. Our preliminary results suggest that acetylation of DJ-1 and SOD1 suppress their anti-oxidant functions, while acetylation of 14-3-3z disrupts its binding to pro-survival proteins. Taken together, our data support a model in which cytosolic Sirt1 activates multiple pathways that work together to promote tumor cell survival.

Hyrum Shumway, Brigham Young University Microbiology and Molecular Biology Epigenetics is the study of factors of gene regulation that do not stem from the primary DNA sequence. One such example of epigenetic gene regulation is where DNA wraps around histone proteins to form nucleosomes. The positioning of nucleosomes is the first order of control for genic transcription. Wrapped DNA is less accessible for transcription compared to DNA that is nucleosome free. Model organisms for human epigenetics such as the nematode Caenorhabditis elegans are invaluable because of their ease in manipulation and because the components of nucleosomes (histone proteins and DNA) are highly conserved across phylogeny. The purpose of my particular research is to develop and validate a new protocol for tissue-specific isolation of nucleosomes through immunoprecipitation in young adult C. elegans. This protocol leverages green fluorescent protein fused to histones to research nucleosome positioning in the germ-line cells of C. elegans nematodes. When successful in our animal model, this procedure is the first step in allowing analysis of chromatin architecture of any tissue at any developmental or disease state including human cells. The widespread prevalence and implications of human disease is staggering in magnitude. Research is ongoing to decrease morbidity, increase prevention, and fight infection. With epigenetic tools, this vital research is benefitted and supplemented.

Harsh Kansagra, Southern Utah University Biology Anthoxanthum hirtum is a native grass with many traditional and modern uses, including human medicinal benefits. Populations are found locally in Utah, but at higher elevations, usually above 2500 m. Indigenous people used native sweetgrass in a variety of ways, including medicinally, as ceremonial incense, and in basketry. The active compound that elicits the sweet fragrance of the grass is produced by coumarin, a secondary metabolite used today both medicinally and commercially. Plants most often produce secondary metabolites, or essential oils, as a defense against pathogens, but these antimicrobial properties have not been investigated in A. hirtum. Our research used the Kirby-Bauer disk diffusion test to determine if closely related commercial diploid and polyploid sweetgrass strains (Anthoxanthum odoratum), as well as plants from native A. hirtum populations, produce zones of inhibition when tested against associated soil bacteria and fungi. Results of our research showed all species tested produced inhibition zones, but zone size varied in response to the secondary metabolites produced by each plant type. Despite this variation, these data suggest components of the essential oils may have antimicrobial properties. Results of this study increase our understanding of the antimicrobial properties of secondary metabolites produced by A. hirtum as well as the essential oils produced by commercial diploid and polyploid strains. Future studies will focus on identifying the chemical composition of each extract as well as the specific bacterial and fungal species associated with each plant.

Ji Su Park, Brigham Young University Nutrition, Dietetics, and Food Science Selenium (Se) and soy have each been shown to reduce risk for prostate cancer when consumed at high levels. The purpose of this project was to define the molecular mechanisms of prostate cancer chemoprevention by Se and soy, and to describe how timing of dietary treatment modifies those effects. [C57BL/6 X FVB] F1 TRAMP (TRansgenic Adenocarcinoma of Mouse Prostate) male mice were fed stock diets high or low in soy, with or without a supplement of Se (4.0 mg Se/kg BW as Se-meth- ylselenocysteine) by gavage 5 d/wk in a 2 X 2 factorial design. Mice were exposed to different diets starting from conception, 6 weeks, or 12 weeks of age and were sacrificed at 18 weeks. Three-way ANOVA showed that supplemental Se increased serum and liver Se, with significant interactions with both time and soy intake. Selenium dosing decreased BW independent of soy intake and time of dietary intervention. Both Se and soy decreased epididymal fat pad weights, with Se’s effects being more pronounced in mice exposed to diets from conception than from 6 wk. Urogenital tract weights, a measure of prostate proliferation and tumor volume, were significantly reduced by Se supplementation (P<0.001) and soy (p=0.044), independent of time of dietary intervention. Histological examination of mouse prostates is in progress to determine dietary effects on disease progression. These data suggest that, in this model, chemopreventive efficacy of Se and soy does not differ between prenatal and early post-natal introduction.

Marcus Vranes, Brigham Young University Molecular Biology Recent studies have attempted to discover the correlation that exists between DNA methylation and nucleosome positioning, but none have explored the direct effect of DNA methylation on nucleosome formation and positioning. This proposed research will directly test the effects DNA methylation has on nucleosome positioning and whether the histone octamer has preferred sequences to which it binds, which will in turn add our understanding of gene expression and regulation. A better understanding of these concepts will help to aid efforts in gene therapy to better the quality of life of many who suffer from various genetic conditions.

Sarah Miller, Southern Utah University Agriculture and Nutrition Science The high intake of fat in the average American diet is a growing concern to the nutritional community. High levels of total fat intake increase cardiovascular disease (CVD) which is the number one killer in America. The successful development of low fat recipes that can be accessed and produced by the general population is valuable to the fight against obesity and CVD. If acceptable products can be made with lower fat content then it is possible to lower the fat intake in a person’s diet. This study is designed to test the acceptability of low-fat desserts using every day food products available for home use as fat substitutes. Four popular “name-brand” recipes were altered by removing 55-73% of the fat and replacing it with a common food item, either pureed white or pinto beans, applesauce or yogurt. Southern Utah University students were recruited via flyers, in class announcements, and word of mouth. Participants (n=56) were asked to taste and evaluate the four products. Afterwards they completed a short survey about their knowledge of low-fat food substitutes and acceptability of the products. Results and conclusions forthcoming.

Sarah Miller, Southern Utah University Biology As humans, we have the ability to change our diets if we are deficient in any specific nutrient. Many animals have the ability to change their diet if they are deficient in nutrients. However, for many carnivores, it is generally thought that a prey item will have the same nutritional composition as the predator body composition. Carnivores are limited nutritionally in their diet. This means that they only get nutrients from the prey that they are able to locate to consume. This study is investigating prey choice of invertebrate predators (wolf spiders) when their prey item has been altered to be deficient in one specific nutrient (lipid or protein). I predict that the spiders will be able to choose the correct prey item for the nutrient in which they are deficient. The total weight of flies eaten in each treatment will be measured to determine if wolf spiders select prey items based on the nutrient content of the prey. Results will be analyzed using a nested ANOVA.

Adrian Scottorn, Salt Lake Community College Natural Sciences Chocolate has long been the favorite snack of many, and recent studies have shown multiple positive health benefits of eating dark chocolate in particular, encouraging production and consumption of very high cacao content bars. We have quantified some of the changes that occur to the amount of known flavor compounds contained in a locally made artisan chocolate. The bars we chose were 70% minimum single origin cacao made with as few other ingredients as possible. By first measuring the amount of known flavor compounds, then stressing the bars in various ways, we looked in to what really happens when a quality chocolate bar is mistreated.

Michael Peterson, Brigham Young University Biology A person’s predisposition to Alzheimer’s Disease is known to be influenced by both genetic factors as well as environmental factors. One know environmental factor is that known to affect risk for disease is early parental death. The purpose of this research is to better understand the complex factors that influence the disease by analyzing the relationship between the environmental factor of early parental death with genetic variants known to influence the disease. We used extant data from the CCSMHA, an ongoing aging study including 89.7% (5092 of 5677) of all of the eligible residents of Cache County, Utah. This data includes information about environmental and psychosocial stressor of the subjects as well as information about physical examinations, metal screenings, and individuals’ genotypes at many loci that are known to be related to Alzheimers Disease. We used multivariate logistic regression to determine the effect of early parental death by SNP interactions on risk for AD. For the analysis we cleaned the data by removing SNPs less than a minor allele frequency of 0.01, a Hardy-Weinberg equilibrium value of 110-6, and a maximum missing snp call of 0.2. Individuals were also removed if genotyping rate was less than 0.2. After filtering we had 262 cases, 239 controls and 0 missing Final Results will be presented at the Conference.

Rachel Perry, Brigham Young University Life Sciences Previous studies have indicated that Visinin-like protein (VILIP) may be a powerful tool in predicting disease progression and guiding prognosis of Alzheimer’s disease (AD). Cerebral spinal fluid (CSF) was collected from hundreds of individuals with varying levels of AD. The CSF was then analyzed for levels of VILIP protein using Luminex technology. SNPs were genotyped using the Illumina OmniExpress chip. SNPs found to have a Hardy-Weinberg frequency less than 1×10-4 were not included, assuming that this variance was due to a genotyping error. SNPs and samples missing more than five percent of the data were also not included. Following the cleanup of the data, an association test using linear regression was performed. Covariates used in the analysis included age, gender, and covariates that accounted for population stratification (PC1 and PC2). Over one hundred SNPs were found with a p-value less than 1×10-5. The genomic inflation factor for the generated data was 1. One marker showed significance at the genome-wide level. We have identified a genetic marker that shows significant association with CSF VILIP levels. This finding may provide insight into genetic control of VILIP levels, which may be a useful in understanding the pathological processes involved in AD.

Chris Thurman, Salt Lake Community College Natural Sciences This project is an ongoing multifaceted investigation of the Jordan River. The study’s intent is to monitor and asses the overall condition of the river from Utah Lake to the Great Salt Lake. Samples of river and pond water, typical vegetation such as cattails, and some soils have been collected with reference to sites along the river that may serve as sites for the introduction of waste and other contaminants. These samples have so far been examined with respect to temperature and dissolved oxygen at the sampling point. Two river samples, one pond sample, and plant sample have been analyzed by ICP-MS for 20 different metals. The levels of Lead, Cadmium, and Copper have been determined by anodic stripping voltammetry at the ppb level in a variety of other water samples from the river. The results of these measurements are disused and presented Geospatially.

Matthew Schneider, Brigham Young University Physiology and Developmental Biology Alzheimer’s disease, the most common form of dementia, affects millions of people per year. Research has shown that Alzheimer’s affects the hippocampus brain region, which is involved in learning and memory. Understanding learning and memory functions is imperative to comprehending both healthy brain functions and Alzheimer’s disease. Many researchers seek to understand both the causes and treatments of the disease, but tangible information remains elusive. Studies thus far have shown that to encode memories, the brain must change neural synapses to either strengthen or weaken those pathways, a process known as synaptic plasticity. Using electrophysiology techniques on mouse hippocampal slices, this project will provide further insight on memory formation and regulation by imitating synaptic plasticity mechanisms. I will look at a specific cellular pathway involving the protein receptor GPR55, which has recently been shown to induce synaptic plasticity. By understanding how the GPR55 pathway functions, this research will contribute to the understanding and treatments of Alzheimer’s and other neurodegenerative diseases.

Lacie Cates, Salt Lake Community College Natural Sciences According to the Salt Lake Valley Health Department 1 the optimal level of fluoride is 0 .7 to 1.2 ppm in drinking water. Also acidity of many foods and drinks leads to tooth decay. In 2003 the State of Utah started adding fluoride to tap water. Then in 2008 Utah counties voted on addition of fluoride resulting in a variation of water treatment from county to county. At present the state has about 50% of the population receiving fluoride treated water with the aim of providing the 1 ppm fluoride level. It has also been reported that some counties are considering cutting back to about 0.7 ppm 2 . This study examined the pH and fluoride content of water samples from the major population counties in Utah. Fluoride levels ranged from 0.08 – 0.92 ppm. The pH values for these samples ranged from 6.26 -8.08. A further study of the fluoride levels and pH in bottled water and other drinks and foods such as fruit and cheese was conducted because many people in Utah do not drink tap water, particularly in regions of high water hardness or areas where taste and / or odor can be off putting. The pH values ranged from 2 to 8. The most acidic being colas and citrus based drinks and foods. The fluoride values varied from 0.03 to 0.47 ppm.

Kristian Johnson, Dixie State University Biology Antimicrobial methods, such antibiotics and Ultraviolet (UV) irradiation, have been a means of suppressing prokaryote proliferation for nearly a century. Over the last several years, scientists have found that numerous strains of prokaryotes have developed resistance to antibiotics. Concurrently, the process of bacterial irradiation using UV-C is common practice in a variety of sterilization applications. As revealed in the seminal work by Chang et al. inactivation curves for Microorganisms such as Staphylococcus aureus (Staph) were established in 1985. Their values indicate survival rates based on Intensity, which is defined as the time of UV irradiance per unit area. Similar to the evolutionary evidence of antibiotic resistance, we are interested in the selective pressure UV-C has on Staph. By recapitulating Chang’s experiment nearly 30 years later, our preliminary results indicate an increased resistance to UV-C in Staph. In this experiment, we determine a current UV-C dose-dependent kill rate function for Staph.

Chancen Hall and Nichkolas Hadley, Dixie State University Biological Sciences Batrachochytrium dendrobatidis (chytrid fungus) is prevalent worldwide, and the resulting chytridiomycosis has contributed to at least 168 amphibian species extinctions. In 2010, B. dendrobatidis was discovered in the greater Zion National Park area of southwestern Utah. Because few populations have shown resistance to chytridiomycosis, we decided to explore the effects of this disease on populations of Hyla arenicolor (canyon tree frog). We tracked the spread of B. dendrobatidis by testing skin samples taken annually from several different canyons and monitored population sizes. During the three years of our study, infected populations did not show subsequent population declines. This suggests that H. arenicolor population size in this region is unaffected by B. dendrobatidis. In the future, testing hypothesized explanations for surviving infection could help us identify populations not at risk and thus allocate conservation resources more efficiently.

Rachel Schneider, Brigham Young University Neuroscience The ability to create distinct memories for very similar stimuli and events is called pattern separation. Pattern separation is thought to be dependent on neurogenesis (the birth of new neurons) in the dentate gyrus, a subregion of the hippocampus. Neurogenesis is reduced in depression, as is overall memory performance. It has been proposed that depression negatively impacts pattern separation abilities, however a link between depression and performance in pattern separation memory tasks has yet to be identified. Accordingly, we designed a study to investigate the relationship between pattern separation performance and level of depression. Eighty-two participants completed a pattern separation memory test and a set of questionnaires to gauge their level of depression. During the task, participants were presented with 600 images one at a time on a computer screen in a continuous recognition paradigm. Participants were asked to determine whether each image was new, old, or similar. Images seen for the first time during the task qualified as “new”, images that were repeated following a variable delay qualified as “old”, and images that were similar to previously presented stimuli, but not exactly the same, qualified as “similar”. A pattern separation score was calculated based on the proportion of correctly identified similar stimuli. We found a negative correlation between depression scores and pattern separation scores (r(82) = – 0.301, p < 0.01). This relationship held constant even when we controlled for other factors known to affect neurogenesis, such as exercise and anxiety levels. These results provide support for the theory that depression is negatively related to pattern separation performance, possibly due to a decrease in neurogenesis in the hippocampus.

Michael Barney, Southern Utah University Biology Parkinson’s disease is caused by a decrease in dopaminergic neurons in the substantia nigra, which results in a loss of motor control. Although the exact causes of Parkinson’s disease are unclear, studies have shown that exposure to environmental contaminants causes death of cells in the substantia nigra (McCormack et al., 2002). The purpose of our study is to investigate the potential role of fire retardant as a risk factor for Parkinson’s disease. We subcutaneously injected 8 experimental mice with retardant solution (1 ml/60 g body weight) and 7 control mice with saline solution (1 ml/60 g body weight). Each mouse was given 8 injections over four weeks, after which the mice were sacrificed and brains were harvested. Frozen sections (40 mm thick) were mounted on slides and are being processed using anti-tyrosine hydroxylase, which will be visualized using a peroxidase reaction. The number of cells in the substantia nigra will be counted and compared between control and experimental groups. Our hypothesis is that exposure to fire retardant is a risk factor for Parkinson’s disease. If this hypothesis is supported, this would be the first study to show a link between fire retardants and Parkinson’s disease. This would have important implications for current forest fire fighting techniques.

Ryan Williamson, Brigham Young University Physiology and Developmental Biology The hippocampus is thought to mediate learning and memory by altering the strength of synapses within its circuitry. In many cases, this synaptic plasticity can be induced by intracellular signaling molecules. Lipid-based intracellular signaling molecules called endocannabinoids have been shown to modulate or mediate synaptic plasticity among hippocampal pyramidal cells and stratum radiatum interneurons; however, the role of endocannabinoids in mediating synaptic plasticity among interneurons in the stratum oriens is still unclear. Our goal was to determine whether stratum oriens interneurons have the machinery necessary for endocannabinoid production and, if so, whether this machinery is expressed in a sub-type specific manner. To do this, we used patch clamp electrodes to extract single cells from rat hippocampal slices and analyzed the expression of endocannabinoid biosynthetic enzyme mRNA using quantitative real-time PCR. In this analysis, we examined cellular expression of two interneuron markers, GAD65 and GAD67, as well as several calcium-binding proteins and neuropeptides to determine interneuron subtype. We also analyzed cellular expression of several endocannabinoid biosynthetic enzymes, including N-acyl phosphatidylethanolamine phospholipase D, diacylglycerol lipase alpha, and 12-lipoxygenase, as well as type I metabotropic glutamate receptors. Preliminary data suggests that stratum oriens interneurons express mRNA necessary for endocannabinoid biosynthetic enzymes. Additionally, we identified interneurons that coexpress mRNA for somatostatin and diacylglycerol lipase, suggesting that O-LM cells or another somatostatin-positive interneuron subtype may possess the enzymes necessary to produce the endocannabinoid 2-arachidonoylglycerol. Further work will allow us to examine how endocannabinoid biosynthetic enzyme expression correlates with other interneuron subtypes in the stratum oriens.

Aaron Sharp, Brigham Young University Biology The Cache County study on memory, health, and aging has played a significant role in several studies. However, there is some potential skepticism in the scientific community about its sample. The population in Cache County is derived from a diverse group of founders, but it is perceived by some to be an isolated population. If so, conclusions discovered there might not apply to other populations. Our objective is to compare the Cache County data to a panel of genetic data—provided by the International HapMap Project and the Alzheimer’s Disease Neuroimaging initiative—that is known to be representative of typical European-American populations. Doing so will indicate whether the genetic diversity in the Cache County sample is characteristic of an isolate or not. Analysis will be done using the open source “Plink” analysis toolset, including the –cluster and –mds-plot computational algorithms. Using –cluster groups individuals according to identity by state distances. The –mds-plot algorithm creates a scatter-plot of the individuals in 2-dimensional space, identifying any systematic difference between the Cache County data and the general population. We expect that the Cache County data will be representative of general European-American populations, because of its diverse group of founders.

Paige McAllister, Brigham Young University Psychology Negative body image among younger women has grave ramifications including eating disorders, depression, anxiety, and low self-esteem. In order to more accurately detect negative body image among women, we created the Body Image and Social Comparison Survey (BISCS). The BISCS is a 10 item self-report measure using a 4-point Likert scale. Our two domains were attitudes about personal body image and social comparisons. We took a convenience sample of 115 women between the ages of 18 and 30 and administered our survey to establish psychometrics for the BISCS. It was discovered that the BISCS has high internal consistency, and 43 out of 45 of the Pearson correlations between items were significant. Factor analysis revealed two primary factors. All questions loaded onto the factors we expected them to except there was one question that loaded onto both factors. Content validity ratios ranged from .48 to .81. Future applications and improvements for the BISCS are discussed.

Sasha Trae, Dixie State University Communication This research critiques prevailing economic, political, and social discourses that create or uphold disadvantage, inequity, and oppression against women. Using multiple Critical Discourse Analysis tools, such as, lexical suppression and absence and representational strategies, this researcher will examine activist, political, and socio-cultural discourse, including Take Back The Night, to expose underlying ideology. This paper analyzes ideological functions of these and other constructions identified in the discourse. This researcher will illustrate how the analyzed discourse shapes our reality that the ownership of women’s equality and safety are in the hands of men. Additionally, this researcher will unveil the ideological suppression and absence of the perpetrator; consequently, twenty-first century public discourse places the responsibility in the hands of women to prevent and address violence against women, the victims. Further, this researcher will demonstrate how the revealed ideologies indicate that violence against women is random or unstoppable; thus, setting up women to continue being integrated into a system that is hostile to them. Moreover, the breadth of this ideology indicates that every society within the nations of our world declare that women are a subset of humanity, and that it is men who get to resist relinquishing this equality while women expend their efforts to obtain it. This paper concludes that violence against women is part of an economic and political system that has been codified and written into the laws of nations; therefore, creating and perpetuating the very structures responsible for the violent climate that we fear and live in.

Marlee Olsen, Snow College Psychology This study focuses on how college students interpret and understand new knowledge. Participants will be answering a number of questions via survey about their personal beliefs such as religion, reliable sources of knowledge, and other possible mitigating factors. After reviewing existing research, we found studies being done over long-term acceptance of beliefs, and also studies of the affects on understanding and acceptance of new beliefs after exposure to relative information. However as we reviewed the literature we found lacking information specifically regarding whether college students, when exposed to new concepts, accept the information before understanding it, or postpone acceptance until further understanding. The survey will be given out to students in different geographic regions across the nation to obtain various religious backgrounds, race, gender, and geographic background. We project to find a correlation between religiosity and the rate of acceptance of new beliefs before understanding. Other mitigating factors such as ratings for source of knowledge and geographic background are expected to also have affects. Results will be discussed.

Laura Steffen, Brigham Young University Psychology There is a wide spectrum of opinion on female gender roles, or what behaviors are appropriate for women. Attitudes towards gender roles can hypothetically be influenced by a variety of factors, including religion. Sexist views have been found to be held by members of many faiths, including Catholics, Muslims, and Evangelical Christians (Glick, Lameiras, & Castro, 2002; Maltby, Hall, Anderson & Edwards, 2010; Tasdemir & Sakalli-Ugarlu, 2010). To our knowledge, this phenomenon had not yet been studied among members of the Church of Jesus Christ of Latter-day Saints (LDS). Our measure, the LDS Attitudes Towards Female Gender Roles Scale, (LDS-AFGR) was created in the hopes of accurately assessing opinions of female gender roles among the LDS population, in regards to both religious social contexts. All questions on the LDS-AFGR yielded superior to moderate content validity, and two components were yielded by factor analysis. This suggests that our scale has initial promise, and could be further revised to obtain more accurate data about opinions on female gender roles among LDS church members.

Tida Blackburn, University of Utah Psychology Previous work has shown that our perception of height is influenced by ones eye height. We further investigate this phenomenon by extending this research to virtual reality. Virtual reality can give the appearance of eyeheight change, which cannot be done otherwise. We changed participants’ eye height by adjusting the height at which participants viewed their environment. Effective eye heights were both 0.08 cm lower and higher than the participants’ normal eye height. The virtual reality environment was a classroom with two vertical poles and a horizontal pole that create a horizontal barrier for participants to walk under. In the first experiment, participants were instructed to walk under the barrier as naturally as possible and to duck when needed. The height of the barrier was altered across trials. In the second experiment, we manipulated eye height further using physical objects, namely shoe inserts. The second experiment followed the design of the first experiment. Data was collected using cameras and a tracking program to record the participants’ ducking behavior. The previous study found that manipulating a person’s height influences their judgment of how high the horizontal barrier appears and whether they could pass under it without ducking. We hypothesized that people will change their ducking behavior depending on their eye height, because they are rescaling their body to their new viewpoint.

Adrianne Miller, Brigham Young University Psychology Recent studies in rhesus macaques suggest that social competence and sociality, as measured by ease of forming new relationships, is modulated by genetic and behavioral factors. In research centers that study primates, pairing unfamiliar subjects is the most costly and difficult problem that researchers face. We investigated several factors believed to influence social competence: rearing condition, serotonin transporter genotype (5HTT), temperament, and stress responsiveness, as measured by infant plasma cortisol levels. We assessed 354 pairings from subjects housed at the California National Primate Research Center (n=177 male and n=177 female adult pairings). Temperament and plasma cortisol was assessed at three to four months of age. Analyses showed that males were more difficult to pair than females. High cortisol, nursery rearing, and temperament ratings for high emotionality during infancy was predictive of adult pairing failures. Intriguingly, our data showed that the high risk 5HTT genotype was also predictive pairing failures, and that 5HTT genotype interacted with sex, with pairs of males where one or more of the subjects in a pair possessed the high risk 5HTT allele were more likely to be unsuccessful in their pairings. To the extent that our results generalize to humans, our data suggest that early temperament, perhaps modulated by the serotonin transporter genotype, as well as sex and early experiences lead to social competence and success in social relationships.

Jordin Kirkham, Snow College Psychology The purpose of this study is to observe, and analyze how average college students perceive professors in the media and if these perceptions have an effect on our own personal behaviors in the setting of a classroom, the influence of grades, and other factors. Based upon the review of literature, we have discovered that many of the studies regarding professors in the media have barley skimmed the surface, not providing much detail. We plan on going into more depth in our personal observation-analysis studies, seeing how we mainly perceive professors in movies, television, books, newspapers, etc. Results will be discussed.

Jyssica Seebeck, Brigham Young University Psychology Until recently, there were very few meta-analytic comparisons between individual and group formats to determine if reliable outcomes were produced. However, Burlingame, Strauss, and Joyce (2013) recently identified a dozen diagnosis specific meta-analyses (bipolar disorder, schizophrenia, etc.) and twenty-three new studies published over the last decade that test for differential format efficacy/effectiveness. This meta-analysis builds upon these by selecting the most rigorous studies drawn from these meta-analyses. More specifically we selected studies that tested equivalent treatments enabling us to make strong causal conclusions about differential efficacy/effectiveness. We began with published meta-analyses that tested for format differences, went to each and determined whether individual studies summarized in these meta-analyses compared treatments that were equivalent. If they did, the study was included herein. We also conducted a literature search to identify studies that tested individual and group treatments not included in the aforementioned meta-analyses. Computed effect sizes tested differential outcomes (group versus individual) and also estimated the effectiveness of format compared to waitlist controls. Moderator variables of outcomes, such as group type and theoretical orientation were also tested. Results are reviewed with reference to treatment recommendations, feasibility of implementation, and evidence based recommendations.

Nickolal Mullen, Brigham Young University Psychology Previous studies have shown that the monoamines are related to risk for alcoholism, and that both are affected by early rearing experiences. This study builds on previous research in examining the effect of alcohol on monoamine neurotransmitter systems, by exposing macaques to a set dose of alcohol and measuring CNS monoamine metabolites. We explored

Ryan Woodbury, Brigham Young University Psychology Ample evidence suggests that religiousness can serve as a protective factor against risk behaviors (Regnerus, 2007), and can be an important context for positive youth development (Lerner, Roeser, Phelps, & Benson, 2008). Many correlates of religiousness have been identified, but our understanding of underlying mechanism is still nascent (Regnerus, 2007). Building on the notion of religion as a source of social control, one potential mediator may be religious norms (Cochran, Chamlin, Beeghley, & Fenwick, 2004), or perceptions of the behaviors proscribed and prescribed by religions. Unfortunately, research on religious norms is scarce. Thus, the purpose of the present study was to identify adolescent and parent perceptions of religious norms, examine individual differences in these perceived religious norms, and assess links between perceived norms and adolescent behaviors. Adolescents (N = 419; age range 15-18) and one of their parents (N = 313) completed online surveys. Qualitative questions asked participants to name three behaviors their religion most encouraged adolescents to do and three behaviors their religion most discouraged adolescents to not do. Quantitative measures consisted of ratings of 18 perceived religious norms and frequency of 18 adolescent behaviors. We investigated the following research questions (RQ):RQ 1: What religious norms do adolescents and their parents perceive? Three coders, using grounded theory, placed qualitative responses into themes. Seven themes emerged from adolescents’ and eight themes emerged for parents (see Table 1).RQs 2 and 3: To what extent and in what ways do these religious norms differ by adolescent and parent gender? And, how do these religious norms differ by adolescent and parent religious affiliation? Two MANOVAs (one comparing gender, the other comparing religious affiliation) were run to indicate respective differences. Both qualitative and quantitative religious norms differed between certain religions (not between adolescent gender; see Table 1).RQ 4: To what extent and in what ways do adolescent and parent perceived religious norms correlate? Bivariate correlations between adolescent and parent perceptions of religious norms for negative behaviors ranged from .07 – .51 (M = .26, SD = .09), and for positive behaviors they ranged from -.01 – .53 (M = .31, SD = .10).

Trenton Simmons, Brigham Young University Psychology Endogenous opioids are believed to modulate social sensitivity and aggression. The mu-opioid receptor gene in rhesus macaques has two common variants thought to be orthologous to human variants: C77G (CG) and C77C (CC). Based on previous studies, we predicted that rhesus macaques with the CG variant would exhibit higher rates of antisocial and aggressive behavior during social challenge. To test this hypothesis, we subjected mother-reared (MR) and nursery-reared (NR) subjects to an intruder challenge. 130 subjects were genotyped for the mu-opioid receptor gene variant. Behaviors were recorded after an unfamiliar intruder of the same sex and age was placed adjacent to the subjects’ home cage. CG, MR males received more non-contact aggression from group members than any other condition (p range<0.012), instigated more contact aggression than any other condition (p range<0.018), and received more contact aggression from the intruder than all other conditions except CC, NR males. In contrast to high rates of aggression, male, CG, MR subjects exhibited the lowest time in social affiliation when compared to all other genotype, sex or rearing conditions (p<0.026) except for CG, NR females. Our findings suggest that the mu-opioid receptor gene modulates aggression and antisocial behavior but only in the context of rearing and sex. These findings suggest one potential pathway for antisocial aggressive behavior development in men.

Amanda Stouffer, Snow College Psychology There have been many studies on the topic of magazine covers, whether it is the contents of the magazine or specifically what is depicted on the cover of the magazine. Such studies typically look at the ethnicity, gender, and age of the people shown on magazines’ covers. They also study what trends exist with these different factors. For example the number of women shown on covers is going up. These studies have been done on many magazines including Rolling Stone, Sports Illustrated, Playboy, and Cosmopolitan. These extensive studies have also found an increasing amount of sexual objectification, especially of women. The magazine Psychology Today has not been studied in-depth, but as psychology is a supposedly progressive field that uncovers and empirically studies inequalities one might guess Psychology Today breaks that stigma. However it does not. Through the study of the cover photos of Psychology Today the present study will look at: perceived age, sex, ethnicity, amount of clothing, passive vs. active scene, body parts shown, arousing vs. disturbing picture, whether the overall message is positive

Jenna Jackson, Brigham Young University Psychology We examined the effect of social separation stress and serotonin transporter genotype (5HTT) on behavior during mother-infant (MI) reunions using infant rhesus macaques. Based on previous studies, we predicted that infants and mothers who posses the less efficient short (s) allele would display more anxious and aggressive behaviors in both their relationship and also within the larger social group. MI behaviors were recorded during a reunion period after being separated for five days from their mothers. Subjects were 140 rhesus macaques that were tested in one of two separation conditions: mother removed from the social group with the infant left behind, or the mother and infant were each housed alone in single cages. Time spent in behaviors that characterize MI and peer relationships were recorded as dependent variables, while genotype was used as the independent variable. Results showed that MI interactions were especially affected if both the mother and the infant possessed the Ls genotype. Moreover, infants with the Ls genotype also displayed less social contact with other group members, and higher rates of aggression with their peers. Our findings suggest that when both the mother and the infant possess the 5HTT short allele, the MI relationship is strained, showing higher levels of stress and that peer bonds are also affected negatively by the Ls genotype. To the extent that our findings generalize to the human condition, they suggest that the 5HTT genotype influences environmental conditions to influence the mother-infant bond and other social interactions.

Casey Kidman, Snow College Psychology Many people these days are using emoticons in electronic communication. Our topic of research is how people interpret and define these emoticons. This research will include both high school and college students as well as other individuals. We will have students fill out a survey in which they view an emoticon and then write a one-word or brief description of it. We also will evaluate the false consensus effect by asking them on the survey what percentage of people they believe would agree with the way they define the emoticon. Research thus far has not looked into how emoticons are defined, while there is research on how often they are used and what gender uses them more frequently. There are holes in the current research and we are laying the ground work in answering the question of if and how emoticons are universally defined. We expect the very basic emoticons such as “:)” and “:(“ to be generally defined the same; however, as emoticons get more complex we believe the definitions will vary significantly.

Brian Redford, Brigham Young University Psychology Small group treatment is a well-recognized as an effective intervention for persons diagnosed with schizophrenia. The most frequently used and efficacious types of small group treatment include psychoeducational, multifamily and skills groups. These groups are second only to psychopharmacology and frequency of use (Burlingame, Strauss & Joyce, 2013). Using the following search terms (group psychotherapy OR group counseling OR group treatment AND schizophrenia from 1990-2000) 62 studies were identified that used the aforementioned small group treatments. Of these, 29 were excluded based on strict inclusion criteria (i.e., sample size, study design, statistical methodology). 26 studies produced active group comparisons with controls, 3 studies produced single group pre-post comparisons and 5 studies produced waiting list control comparisons studying 2,248 patients. We conducted a meta-analysis using several descriptive (e.g. setting, ethnicity) and moderator (e.g. age of onset, group type) variables examining outcomes on key dimensions (e.g. relapse, hospitalization, medication adherence). Effect sizes estimated treatment effects (pre to post) and if these effects were maintained (post to follow up). Findings are examined in reference to treatment recommendations, feasibility of implementation and evidence based recommendations with respect to illness, protective, mechanisms of action and risk factors.

Jennifer Campbell, Utah State University Psychology Eating disorders are pervasive mental illnesses that overwhelm the lives of individuals who struggle with them. For individuals with anorexia nervosa or bulimia nervosa who do not respond to other treatments, Acceptance and Commitment Therapy has the potential to be effective. This presentation looks to orient researchers to Acceptance and Commitment Therapy while supplying a potentially useful treatment option for those who struggle with clinical anorexia nervosa or bulimia nervosa. The current literature comes together to support the effectiveness of Acceptance and Commitment Therapy for the treatment of eating disorders, specifically anorexia. This presentation focuses on the symptomatology and physical effects of anorexia and bulimia, as well as core principles and processes of Acceptance and Commitment Therapy. Future directions regarding the effectiveness of Acceptance and Commitment Therapy can be broadened to include adolescents as well as other types of eating disorders, such as binge eating disorder and eating disorders not otherwise specified.

Lauren Miller, Utah State University Psychology Affective disorders such as depression, phobias, schizophrenia, and post-traumatic stress disorder impairs the ability to time in the seconds-to-minutes range, i.e., interval timing. We investigated the effect of chronic administration of selective serotonin reuptake inhibitor fluoxetine (FLX) when anxiety-inducing task-irrelevant distracters are presented during an interval timing task. Given that some anti-depressants have beneficial effects on attention and working memory, e.g., decreasing emotional response to negative events, we hypothesized that FLX would decrease activation of amygdala and increase activation of prefrontal cortex. Our results revealed differential activation of amygdala and prefrontal cortex in FLX and vehicle treated rats corresponding to the expected changes in behavior. Results are discussed in relation to the brain circuits involved in interval timing and emotional processing, and the pharmacological management of affective disorders.

Jordan Roberts, University of Utah Political Science I explore the tragic collision between individual self-determination and collective self-determination. While the conflict between these two ideals exists in many forms throughout political life, I focus on an international manifestation of this collision: the conflict between national sovereignty (predicated on collective self-determination) and international human rights (predicated on individual self-determination). There are perhaps no two international values more acclaimed, and no two values that clash as intensely; to allow for sovereignty means to allow for human rights abuses and to intervene in the name of human rights means to deny sovereignty. Eschewing traditional political lenses, I employ a tragic framework that 1) allows fuller engagement with the conflict and 2) avoids the pitfalls of the traditional lenses, including one-sidedness (which fuels the continuation of the conflict) and detachment (which allows for inaction). I draw on Sophocles’ Antigone, interpreting the title character as an embodiment of individual self-determination and Creon as an embodiment of collective self-determination. Furthermore, I argue that prominent attempts at finding a compromise between the two forces caught in this tragic collision, exemplified by the emerging international norm of Responsibility to Protect (R2P), are blind to the collision’s inherently tragic nature, and thus subvert one or both of the values at stake. I also address how this tragic blindness of notable theorists working on questions concerning human rights and sovereignty reproduces the blindness of another Sophoclean character: Oedipus. While tragic conflicts do not lend themselves to neat and tidy outcomes, a tragic framework embraces the conflict, instead of sidestepping it, and works towards an ambiguous, unhappy solution.

Kevin Korous, University of Utah Psychology The goal of this study was to explore if participation in different types of activities was related to the development of an internal locus of control in middle childhood. It was hypothesized that children who participated in more activities would have more of an internal locus of control than children who participated in fewer activities. Participants consisted of 45 adolescent boys and 99 adolescent girls (M = 10, SD = 1.34). Parents were asked to tell us about the activities their child participated in. The listed activities were grouped into four categories based on prior research: 1) sports based activities; 2) school based activities; 3) arts based activities; and community based activities (Barber, Abbott, Blomfield, & Eccles, 2009). To measure locus of control, participants were asked to tell us why a situation involving conflict with a peer occurred and what he/she would do. Then the narratives were coded for locus of control using a five-point scale. There was a significant difference in locus of control by story, Wilk’s A = .348, F(2, 143) = 37.64, p < .01, partial eta2 =.348. Participants were significantly more likely to report that the act of overt aggression was an event s/he had control over and could resolve independently whereas participants reported that the act of relational aggression was more externally driven resulting in less control over the situation, t(141) = -4.59, p < .01, mean difference = .123. Additionally, the participants reported a lower sense of control over the breaking of a social norm by a peer than they did in response to the acts of overt and relational aggression, t(141) = -4.093, p < .01, mean difference = .108 and t(141) = -8.672, p < .01, mean difference = .115, respectively. There was only one significant correlation among the different types of activities and the participants’ scores on locus of control. Children who participated in more arts based activities demonstrated more of an internal locus of control in response to a peer violating a social norm than children who participated in fewer arts based activities, r(142) = -.234, p < .01.

Yoon Lee, Utah State University Family, Consumer, and Human Development Drug abuse in America is a major problem that has been well documented throughout history. Marijuana use has increased among most age levels and is the most abused illicit drug in America. Cocaine use has also increased over the past decade. Possibly the most alarming trend is the fact that hospital visits due to drug abuse of any kind are dramatically increasing each year. Using data from the National Survey on Drug Use and Health (2010), this study explored to what extent adolescents and young adults were involved with Marijuana or Cocaine abuse and to investigate factors associated with their use of such illicit drugs. For the data analyses, the total sample included 37,926 individuals between the ages of 12 and 25; the sub-sample of this study consisted of Adolescents between the ages of 12 and 17 (n=18,622) and young adults between the ages of 18-25 (n=19,304). The descriptive statistics suggested that among the study sample, 35.3 percent reported they ever used marijuana, while 7.5 percent reported they ever used cocaine. The results of logistic regression analyses show that all else being equal, age, health, gender, race, county size, and illicit drug addiction are statistically significant in predicting the likelihood of reporting marijuana experience among young adults between ages of 12-25. Similarly, the results of logistic regression analyses show that all else being equal, age, health, gender, education, race, county size, and illicit drug addiction are statistically significant in predicting the likelihood of reporting marijuana experience among young adults between ages of 12-25.

Kevin Lawanto, Utah State University Psychology Mice are excellent models for studying aggressive behaviors and the neural circuits underlying aggression. They identify their conspecifics through olfactory communication within the animal group (emission scent marking and detection of volatile and nonvolatile chemicals, such as pheromones). Anomalies in the perception and processing of olfactory cues may induce abnormal social behavior, anxiety or aggression. We performed a behavioral assessment of male NrCAM knockout mice and wild-type littermates. We found that NrCAM-deficient male mice exhibit increased aggression towards unknown conspecifics. Using cFos immunostaining, we revealed differences in neuronal activation between NrCAM knockout mice and wildtype littermates in a circuit relevant to processing of olfactory cues and male-specific behaviors (olfactory bulb, amygdala, bed nucleus of the stria terminalis and hypothalamus). These differences may be the result of misrepresentation of olfactory cues due to abnormal neuronal connectivity in the olfactory system. Our studies may be relevant to pathophysiological mechanisms responsible for abnormal social behaviors, aggression and anxiety.

Elizabeth Payne, Utah State University Anthropology This paper is an exploratory ethnographic research project designed to collect stories of health care experiences of childbirth in Cache Valley, Utah. By interviewing women who have given birth in Cache Valley, key themes have been identified as being significant to the childbirth community, these are; the Biomedicalization of childbirth; Tensions between the biomedical and holistic out-of-hospital approaches to births; Out-of-control pitocin use; and the Beliefs and Attitudes associated with giving birth. I compare the results with my own experiences as well as in the literature. The discussions raises issues of concern and an applied suggested course of action is offered to policy makers.

Eric Hastings, Utah State University Psychology Does building a new school facility change the quality of the school learning environment? If so, how enduring are these effects? Research shows some correlation between the physical environment of a school and student outcomes to. However, research fails to demonstrate that drastic changes to the environment through reconstruction influence those same outcomes. To investigate this relationship a group of newly built/reconstructed schools was identified and looked at longitudinally to measure the quality of the school’s learning environment two years before construction and four years after construction. To measure the school’s learning environment this research used the Indicators of School Quality survey (ISQ); a comprehensive survey system for school administrators to evaluate and monitor school improvement and accreditation efforts which provides information on the status of the schools learning environment, year to year progress and details about the conditions for learning produced in the classrooms. ISQ does this by measuring parent, teacher, and student perceptions of things such as parent support, teacher excellence, student commitment, school leadership, instructional quality, resource management, and school safety. In addition to the impact of school construction on a school’s learning environment, this analysis was extended to student attendance, safety, and student academic achievement. Data collected to this point supports the argument that school construction only has short term effects on a school’s learning environment, but no long lasting effect. Instead of investing in new facilities, schools and districts would be wise to first consider giving more attention to maintaining student and teacher relationships.

Alysha Waters, Utah State University Psychology Emotional distracters impair cognitive function. Emotional processing is dysregulated in affective disorders such as depression, phobias, schizophrenia, and post-traumatic stress disorder. Among the processes impaired by emotional distracters, and whose dysregulation is documented in affective disorders, is the ability to time in the seconds-to-minutes range, i.e., interval timing. Presentation of task-irrelevant distracters during a timing task results in a delay in responding suggesting a failure to maintain subjective time in working memory, possibly due to attentional and working memory resources being diverted away from timing, as proposed by the Relative Time-Sharing (RTS) model. We investigated the role of the prelimbic cortex (PrL) in the detrimental effect of anxiety-inducing task-irrelevant distracters on the cognitive ability to keep track of time, using local infusions of selective serotonin reuptake inhibitor fluoxetine (FLX). Given that some anti-depressants have beneficial effects on attention and working memory, e.g., decreasing emotional response to negative events, we hypothesized that FLX would improve maintenance of information in working memory in trials with distracters, resulting in a decrease of the disruptive effect of emotional events on the timekeeping abilities. Our results revealed a dissociation of the effects of FLX infusion in PrL between interval timing and resource allocation, and between neutral and anxiety-inducing distraction. FLX was effective only during trials with distracters, but not during trials without distracters. FLX reduced the detrimental effect of the distracters only when the distracters were anxiety-inducing, but not when they were neutral. Results are discussed in relation to the brain circuits involved in RTS of resources, and the pharmacological management of affective disorders.

Karen Yu, University of Utah Psychology Objective