2013 Abstracts

Matthew Whited, Brigham Young University Biochemistry Several lines of evidence suggest that protein lysine acetylation pathways are deregulated in cancer (1). Moreover, deacetylase inhibitors are emerging as important anti-tumor therapeutics, suggesting that the forced reprogramming of protein-lysine acetylation is toxic to tumor cells. In this study we show that Sirt1, an NAD+-dependent Sirtuin deacetylase that promotes cancer cell survival, is aberrantly mislocalized to the cytoplasm of breast tumor cells. Moreover, the depletion of cytosolic Sirt1 by siRNA sensitizes breast tumor cells to paclitaxel-induced death. Previously, we developed a biotin-switch proteomics approach to identify cytosolic Sirt1 substrates (2). This approach yielded a variety of substrates with roles in metabolism, survival, and oxidative stress signaling. Our current work focuses on three of the proteins identified as Sirt1 substrates: SOD1, DJ-1, and 14-3-3z. SOD1 and DJ-1 both suppress oxidative stress-induced death, and high levels of 14-3-3z expression suppress chemotherapy-induced apoptosis and correlate with negative patient outcomes in breast cancer. Our preliminary results suggest that acetylation of DJ-1 and SOD1 suppress their anti-oxidant functions, while acetylation of 14-3-3z disrupts its binding to pro-survival proteins. Taken together, our data support a model in which cytosolic Sirt1 activates multiple pathways that work together to promote tumor cell survival.

Hyrum Shumway, Brigham Young University Microbiology and Molecular Biology Epigenetics is the study of factors of gene regulation that do not stem from the primary DNA sequence. One such example of epigenetic gene regulation is where DNA wraps around histone proteins to form nucleosomes. The positioning of nucleosomes is the first order of control for genic transcription. Wrapped DNA is less accessible for transcription compared to DNA that is nucleosome free. Model organisms for human epigenetics such as the nematode Caenorhabditis elegans are invaluable because of their ease in manipulation and because the components of nucleosomes (histone proteins and DNA) are highly conserved across phylogeny. The purpose of my particular research is to develop and validate a new protocol for tissue-specific isolation of nucleosomes through immunoprecipitation in young adult C. elegans. This protocol leverages green fluorescent protein fused to histones to research nucleosome positioning in the germ-line cells of C. elegans nematodes. When successful in our animal model, this procedure is the first step in allowing analysis of chromatin architecture of any tissue at any developmental or disease state including human cells. The widespread prevalence and implications of human disease is staggering in magnitude. Research is ongoing to decrease morbidity, increase prevention, and fight infection. With epigenetic tools, this vital research is benefitted and supplemented.

Jason Chen, University of Utah Biology Both human language and birdsong are learned sensorimotor processes that require exposure to adult communication signals in order to be reproduced. The social aspect of the development of these vocal signals is distinctive because interaction is not required for the development of vocal signals in other organisms. Human infants isolated from interaction will not learn to speak normally. The need for interaction is also characteristic of the ontogeny of vocal signals in the zebra finch (Taeniopygia guttata), but only zebra finch males develop vocal signals, in the form of song. Juveniles raised in isolation will develop highly atypical song characterized by prolonged, monotonic syllables and irregular rhythms. When juveniles are tutored by these isolated birds in one-on-one conditions their song drifts towards normally raised birds. It is unclear how tutoring, as a social interaction, influences this observation. We hypothesized that different social experience influences birdsong. We predicted the song of juveniles raised in isolation with an experienced female to be closer to normal song than that of those raised in isolated sibling groups, or those raised in isolation. Current data suggest that the syntax and temporal features of song from juveniles raised in isolation with experienced females is indeed closer to normal song than that of isolated juveniles.

Harsh Kansagra, Southern Utah University Biology Anthoxanthum hirtum is a native grass with many traditional and modern uses, including human medicinal benefits. Populations are found locally in Utah, but at higher elevations, usually above 2500 m. Indigenous people used native sweetgrass in a variety of ways, including medicinally, as ceremonial incense, and in basketry. The active compound that elicits the sweet fragrance of the grass is produced by coumarin, a secondary metabolite used today both medicinally and commercially. Plants most often produce secondary metabolites, or essential oils, as a defense against pathogens, but these antimicrobial properties have not been investigated in A. hirtum. Our research used the Kirby-Bauer disk diffusion test to determine if closely related commercial diploid and polyploid sweetgrass strains (Anthoxanthum odoratum), as well as plants from native A. hirtum populations, produce zones of inhibition when tested against associated soil bacteria and fungi. Results of our research showed all species tested produced inhibition zones, but zone size varied in response to the secondary metabolites produced by each plant type. Despite this variation, these data suggest components of the essential oils may have antimicrobial properties. Results of this study increase our understanding of the antimicrobial properties of secondary metabolites produced by A. hirtum as well as the essential oils produced by commercial diploid and polyploid strains. Future studies will focus on identifying the chemical composition of each extract as well as the specific bacterial and fungal species associated with each plant.

Diego Cordero, University of Utah Biology Many zygotes and spores of brown algae are photosensitive and establish a developmental axis in accordance with directional light cues. Ectocarpus siliculosus is being advanced as a genetic and genomic model organism for investigating brown alga development, and this report investigates photopolarization of the growth axis of mitospores. When exposed to unidirectional light, mitospores photopolarized and established a growth axis such that germination was preferentially localized to the shaded hemisphere of the spore body. The roles of the microtubule cytoskeleton and endomembrane cycling in the photopolarization process were investigated using pharmacological agents. Disruption of microtubule dynamics progressively reduced the percentage of mitospores that photopolarized, while inhibition of vesicle secretion blocked photopolarization nearly completely. Chronic treatment with these pharmacological agents severely affected algal morphogenesis. Microtubules in mitospores and algal filaments were imaged by confocal microscopy. Mitospores contained a radial microtubule array emanating from a centrosome associated with the nuclear envelope. At germination, the radial array gradually transitioned into a longitudinal array with microtubules extending into the emerging apex. At mitosis, spindles were aligned with the growth axis of cylindrical cells in the filament, and the division plane bisected the spindle axis. These studies demonstrate that dynamic membrane cycling and microtubule assembly play fundamental roles in photopolarization, and provide a foundation for future genetic and genomic investigations of this important developmental process.

Travis Wood, Southern Utah University Biology Speckled dace, Rhinichthys osculus, is a small minnow that occupies river systems in Utah, Arizona, and Nevada. These minnows prefer clean, faster-moving water with plenty of cover such as rocks or undercuts. The invasive crayfish Orconectes virilis inhabits areas where the Virgin spinedace is found and has a similar diet being an opportunistic feeder. I tested the hypothesis that the natural behavior of Virgin spinedace will be altered due to the presence of crayfish. I predicted that the spinedace would avoid the crayfish and stay out in the open exposing them to a higher risk of predation, since crayfish are a more aggressive organism and will try and eat virtually anything they come into contact with. The experimental trials were conducted (N=24) in Quail Creek, Utah. Large plastic bins with the front and back replaced with screen were used to allow water flow through our experimental chambers. Each bin was placed in the creek and had rocks, and an undercut bank to resemble the native habitat. Controls consisted of placing isolated Virgin spinedace in one of the bins to observe its behavior. In both controls and experimental trials, either 2 spinedace, or 5+ spinedace were added. In experimental trials, I introduced 2 crayfish into the experimental chambers with the Virgin spinedace and allowed them to acclimate for 10 minutes. After the 10 minute acclimation period, behavioral observations were made. Results indicated that when 2 spinedace were present along with the crayfish, they would stay out in the open and the crayfish would occupy the cover or undercut. When 5+ spinedace were present with crayfish, the spinedace displayed a mobbing or “strength in numbers” behavior where they would occupy the undercut and either clog it up with their presence so the crayfish would leave, or mob the crayfish to make them leave. This behavior was opposite of what I predicted would happen. Since this mobbing or “strength in numbers” behavior was not observed with the samples of just 2 spinedace, this may be a behavioral adaptation resulting from the presence crayfish. Further research can be done on the behavioral effects of various fish species in the presence of introduced or invasive species to determine if this behavior is seen in other fishes.

Marcus Vranes, Brigham Young University Molecular Biology Recent studies have attempted to discover the correlation that exists between DNA methylation and nucleosome positioning, but none have explored the direct effect of DNA methylation on nucleosome formation and positioning. This proposed research will directly test the effects DNA methylation has on nucleosome positioning and whether the histone octamer has preferred sequences to which it binds, which will in turn add our understanding of gene expression and regulation. A better understanding of these concepts will help to aid efforts in gene therapy to better the quality of life of many who suffer from various genetic conditions.

Sarah Miller, Southern Utah University Agriculture and Nutrition Science The high intake of fat in the average American diet is a growing concern to the nutritional community. High levels of total fat intake increase cardiovascular disease (CVD) which is the number one killer in America. The successful development of low fat recipes that can be accessed and produced by the general population is valuable to the fight against obesity and CVD. If acceptable products can be made with lower fat content then it is possible to lower the fat intake in a person’s diet. This study is designed to test the acceptability of low-fat desserts using every day food products available for home use as fat substitutes. Four popular “name-brand” recipes were altered by removing 55-73% of the fat and replacing it with a common food item, either pureed white or pinto beans, applesauce or yogurt. Southern Utah University students were recruited via flyers, in class announcements, and word of mouth. Participants (n=56) were asked to taste and evaluate the four products. Afterwards they completed a short survey about their knowledge of low-fat food substitutes and acceptability of the products. Results and conclusions forthcoming.

Sarah Miller, Southern Utah University Biology As humans, we have the ability to change our diets if we are deficient in any specific nutrient. Many animals have the ability to change their diet if they are deficient in nutrients. However, for many carnivores, it is generally thought that a prey item will have the same nutritional composition as the predator body composition. Carnivores are limited nutritionally in their diet. This means that they only get nutrients from the prey that they are able to locate to consume. This study is investigating prey choice of invertebrate predators (wolf spiders) when their prey item has been altered to be deficient in one specific nutrient (lipid or protein). I predict that the spiders will be able to choose the correct prey item for the nutrient in which they are deficient. The total weight of flies eaten in each treatment will be measured to determine if wolf spiders select prey items based on the nutrient content of the prey. Results will be analyzed using a nested ANOVA.

Joshua Horns, University of Utah Biology There are numerous arresting differences between the hands of humans and those of chimps, principally among them the shortening of metacarpals 2-5, the relative increase in length of the thumb, and the development of separate musculature controlling flexion of the thumb. In addition to improving manual dexterity, these changes allow humans, in contrast to chimps and other apes, to make a buttressed fist with the phalanges pressed against the central palm and the thumb adducted onto the dorsal surface of the phalanges. We believe this hand posture greatly reduces the strain experienced by a fully formed fist when striking with force, thereby rendering the human hand as a more effective weapon. We tested this idea by manipulating the tendons in a cadaver arm to induce the hand to form into buttressed and non-buttressed conformations, and then tested each conformation by having the hand strike a hanging instrumented mass to measure the force of each strike. Additionally, the 2nd metacarpal of the hand was fitted with a strain gauge so that strain in the bone could be compared to the force of the strikes. The results of these tests showed that there was a significant drop in strain in the buttressed fist (in comparison to the non-buttressed) for a given force.

Dillon Monroe, Southern Utah University Biology When an area is developed no part of that habitat is left unaffected. Urbanization creates many problems for animals by creating physical barriers, fragmenting habitat, introducing completely new habitat, and introducing species. Exotic species are often better competitors for resources and often competitively exclude native species, resulting in population declines and ecosystem disruption. Despite the negative effects of urbanization some species are able to adapt and survive in urban ecosystems. One such species is the wandering garter snake (Thamnophis elegans vagrans). This species is described as a generalist in habitat selection and is often seen in urban communities basking on sidewalks and pavement, living in gardens, and feeding on rodents, insects, and other species. One unique characteristic of this genus is that prey preference has been observed as being a genetic trait and possesses variation, and as such can be modified via natural selection. For my research project I looked at whether prey preference of T. elegans vagrans differs between snakes from three different locations with varying levels of human development. From these three locations in Utah, Tropic reservoir, Monroe (Sevier River), and Utah Lake, we obtained a total of 14 snakes and found that in this group of snakes there is no correlation of prey preference in snakes to level of development of the habitat.

Adrian Scottorn, Salt Lake Community College Natural Sciences Chocolate has long been the favorite snack of many, and recent studies have shown multiple positive health benefits of eating dark chocolate in particular, encouraging production and consumption of very high cacao content bars. We have quantified some of the changes that occur to the amount of known flavor compounds contained in a locally made artisan chocolate. The bars we chose were 70% minimum single origin cacao made with as few other ingredients as possible. By first measuring the amount of known flavor compounds, then stressing the bars in various ways, we looked in to what really happens when a quality chocolate bar is mistreated.

Makenzie Hawkins, University of Utah Nutrition Cardiovascular disease (CVD) is the leading cause of death in the United States. Gamma-tocopherol (GTC) has been studied in its relation to hypertension and CVD. GTC has protective effects on the endothelium of arteries; the endothelium is in part responsible for regulating arterial relaxation and reducing blood pressure (BP). Diabetic mice (DB) were chosen for this study because of the associated co-morbidities of hypertension and excess body weight. Eight-week-old mice were divided into 3 separate groups: wild-type fed control (CON) diets (n=12), DB fed CON diets (n=12), and DB fed GTC supplemented diets (0.1%, n=12). BP was measured every week for 8 wk. Body weights were measured every wk and morphometric values were measured at the end of the 8-wk period. There was no statistically significant (P<0.05) difference in systolic and diastolic BP between DB-GTC and DB-CON. There was also no statistically significant (P<0.05) difference in heart rate between DB-GTC and DB-CON. After 8 wk, DB-GTC mice had lower (P<0.05) body weight versus the DB-CON group. In conclusion, a GTC supplemented diet did not result in a change in BP. However, GTC may have blunted weight gain and adipose tissue mass in DB-GTC compared to DB-CON. We speculate this may be due to a reduction of food consumption during the experimental period.

Chris Thurman, Salt Lake Community College Natural Sciences This project is an ongoing multifaceted investigation of the Jordan River. The study’s intent is to monitor and asses the overall condition of the river from Utah Lake to the Great Salt Lake. Samples of river and pond water, typical vegetation such as cattails, and some soils have been collected with reference to sites along the river that may serve as sites for the introduction of waste and other contaminants. These samples have so far been examined with respect to temperature and dissolved oxygen at the sampling point. Two river samples, one pond sample, and plant sample have been analyzed by ICP-MS for 20 different metals. The levels of Lead, Cadmium, and Copper have been determined by anodic stripping voltammetry at the ppb level in a variety of other water samples from the river. The results of these measurements are disused and presented Geospatially.

Lacie Cates, Salt Lake Community College Natural Sciences According to the Salt Lake Valley Health Department 1 the optimal level of fluoride is 0 .7 to 1.2 ppm in drinking water. Also acidity of many foods and drinks leads to tooth decay. In 2003 the State of Utah started adding fluoride to tap water. Then in 2008 Utah counties voted on addition of fluoride resulting in a variation of water treatment from county to county. At present the state has about 50% of the population receiving fluoride treated water with the aim of providing the 1 ppm fluoride level. It has also been reported that some counties are considering cutting back to about 0.7 ppm 2 . This study examined the pH and fluoride content of water samples from the major population counties in Utah. Fluoride levels ranged from 0.08 – 0.92 ppm. The pH values for these samples ranged from 6.26 -8.08. A further study of the fluoride levels and pH in bottled water and other drinks and foods such as fruit and cheese was conducted because many people in Utah do not drink tap water, particularly in regions of high water hardness or areas where taste and / or odor can be off putting. The pH values ranged from 2 to 8. The most acidic being colas and citrus based drinks and foods. The fluoride values varied from 0.03 to 0.47 ppm.

Heather Shumway, Southern Utah University Biology Glossiphoniids are jawless leeches that feed using a proboscis, which they use to impale prey so that they can feed on their prey’s blood and tissues. This study focuses on two different species, Glossiphonia complanata and Helobdella stagnalis. Helobdella stagnalis feed on a variety of prey, including bloodworms and freshwater snails, often feeding together in large groups. When a prey item is placed in the container, H. stagnalis immediately begin smelling the water and moving toward the prey. After the first H. stagnalis makes contact and secures prey, other individuals within the group will move to that area, often passing prey along the way, to attach to the same prey item. Once a number of individuals have started feeding, the prey is often broken into smaller pieces and individuals can then begin feeding on various sized pieces. This is in contrast to members of the species Glossiphonia complanata, who appear to be selective with their prey, and have been observed going up to 4 weeks without feeding, even in the presence of their non-preferred prey (bloodworms). When preferred prey (freshwater snails) were placed in the container, unfed G. complanata did not immediately begin smelling the water or initiate hunting. Unlike H. stagnalis which feed in groups, G. complanata appear to prefer feeding alone, and have even exhibited competitive behaviors.

Kristian Johnson, Dixie State University Biology Antimicrobial methods, such antibiotics and Ultraviolet (UV) irradiation, have been a means of suppressing prokaryote proliferation for nearly a century. Over the last several years, scientists have found that numerous strains of prokaryotes have developed resistance to antibiotics. Concurrently, the process of bacterial irradiation using UV-C is common practice in a variety of sterilization applications. As revealed in the seminal work by Chang et al. inactivation curves for Microorganisms such as Staphylococcus aureus (Staph) were established in 1985. Their values indicate survival rates based on Intensity, which is defined as the time of UV irradiance per unit area. Similar to the evolutionary evidence of antibiotic resistance, we are interested in the selective pressure UV-C has on Staph. By recapitulating Chang’s experiment nearly 30 years later, our preliminary results indicate an increased resistance to UV-C in Staph. In this experiment, we determine a current UV-C dose-dependent kill rate function for Staph.

Chancen Hall and Nichkolas Hadley, Dixie State University Biological Sciences Batrachochytrium dendrobatidis (chytrid fungus) is prevalent worldwide, and the resulting chytridiomycosis has contributed to at least 168 amphibian species extinctions. In 2010, B. dendrobatidis was discovered in the greater Zion National Park area of southwestern Utah. Because few populations have shown resistance to chytridiomycosis, we decided to explore the effects of this disease on populations of Hyla arenicolor (canyon tree frog). We tracked the spread of B. dendrobatidis by testing skin samples taken annually from several different canyons and monitored population sizes. During the three years of our study, infected populations did not show subsequent population declines. This suggests that H. arenicolor population size in this region is unaffected by B. dendrobatidis. In the future, testing hypothesized explanations for surviving infection could help us identify populations not at risk and thus allocate conservation resources more efficiently.

Michael Barney, Southern Utah University Biology Parkinson’s disease is caused by a decrease in dopaminergic neurons in the substantia nigra, which results in a loss of motor control. Although the exact causes of Parkinson’s disease are unclear, studies have shown that exposure to environmental contaminants causes death of cells in the substantia nigra (McCormack et al., 2002). The purpose of our study is to investigate the potential role of fire retardant as a risk factor for Parkinson’s disease. We subcutaneously injected 8 experimental mice with retardant solution (1 ml/60 g body weight) and 7 control mice with saline solution (1 ml/60 g body weight). Each mouse was given 8 injections over four weeks, after which the mice were sacrificed and brains were harvested. Frozen sections (40 mm thick) were mounted on slides and are being processed using anti-tyrosine hydroxylase, which will be visualized using a peroxidase reaction. The number of cells in the substantia nigra will be counted and compared between control and experimental groups. Our hypothesis is that exposure to fire retardant is a risk factor for Parkinson’s disease. If this hypothesis is supported, this would be the first study to show a link between fire retardants and Parkinson’s disease. This would have important implications for current forest fire fighting techniques.

Ryan Williamson, Brigham Young University Physiology and Developmental Biology The hippocampus is thought to mediate learning and memory by altering the strength of synapses within its circuitry. In many cases, this synaptic plasticity can be induced by intracellular signaling molecules. Lipid-based intracellular signaling molecules called endocannabinoids have been shown to modulate or mediate synaptic plasticity among hippocampal pyramidal cells and stratum radiatum interneurons; however, the role of endocannabinoids in mediating synaptic plasticity among interneurons in the stratum oriens is still unclear. Our goal was to determine whether stratum oriens interneurons have the machinery necessary for endocannabinoid production and, if so, whether this machinery is expressed in a sub-type specific manner. To do this, we used patch clamp electrodes to extract single cells from rat hippocampal slices and analyzed the expression of endocannabinoid biosynthetic enzyme mRNA using quantitative real-time PCR. In this analysis, we examined cellular expression of two interneuron markers, GAD65 and GAD67, as well as several calcium-binding proteins and neuropeptides to determine interneuron subtype. We also analyzed cellular expression of several endocannabinoid biosynthetic enzymes, including N-acyl phosphatidylethanolamine phospholipase D, diacylglycerol lipase alpha, and 12-lipoxygenase, as well as type I metabotropic glutamate receptors. Preliminary data suggests that stratum oriens interneurons express mRNA necessary for endocannabinoid biosynthetic enzymes. Additionally, we identified interneurons that coexpress mRNA for somatostatin and diacylglycerol lipase, suggesting that O-LM cells or another somatostatin-positive interneuron subtype may possess the enzymes necessary to produce the endocannabinoid 2-arachidonoylglycerol. Further work will allow us to examine how endocannabinoid biosynthetic enzyme expression correlates with other interneuron subtypes in the stratum oriens.

Sean Groathouse, Westminster College Mathematics Strategies for the Colonel Blotto game common in human play are generalized and compared through computer simulation. Furthermore, a variation on the game where the opponent’s resources are unknown is introduced, and differences between the variation and the classic game are explored with simulations on the common human strategies. Another variation on the scoring of the game is introduced and analyzed through simulations and a partial solution to the Nash equilibria in the two-front case.

Paige McAllister, Brigham Young University Psychology Negative body image among younger women has grave ramifications including eating disorders, depression, anxiety, and low self-esteem. In order to more accurately detect negative body image among women, we created the Body Image and Social Comparison Survey (BISCS). The BISCS is a 10 item self-report measure using a 4-point Likert scale. Our two domains were attitudes about personal body image and social comparisons. We took a convenience sample of 115 women between the ages of 18 and 30 and administered our survey to establish psychometrics for the BISCS. It was discovered that the BISCS has high internal consistency, and 43 out of 45 of the Pearson correlations between items were significant. Factor analysis revealed two primary factors. All questions loaded onto the factors we expected them to except there was one question that loaded onto both factors. Content validity ratios ranged from .48 to .81. Future applications and improvements for the BISCS are discussed.

Jenna Jackson, Brigham Young University Psychology We examined the effect of social separation stress and serotonin transporter genotype (5HTT) on behavior during mother-infant (MI) reunions using infant rhesus macaques. Based on previous studies, we predicted that infants and mothers who posses the less efficient short (s) allele would display more anxious and aggressive behaviors in both their relationship and also within the larger social group. MI behaviors were recorded during a reunion period after being separated for five days from their mothers. Subjects were 140 rhesus macaques that were tested in one of two separation conditions: mother removed from the social group with the infant left behind, or the mother and infant were each housed alone in single cages. Time spent in behaviors that characterize MI and peer relationships were recorded as dependent variables, while genotype was used as the independent variable. Results showed that MI interactions were especially affected if both the mother and the infant possessed the Ls genotype. Moreover, infants with the Ls genotype also displayed less social contact with other group members, and higher rates of aggression with their peers. Our findings suggest that when both the mother and the infant possess the 5HTT short allele, the MI relationship is strained, showing higher levels of stress and that peer bonds are also affected negatively by the Ls genotype. To the extent that our findings generalize to the human condition, they suggest that the 5HTT genotype influences environmental conditions to influence the mother-infant bond and other social interactions.

Lisa Heppler, Brigham Young University Chemistry and Biochemistry Solid breast tumors contain heterogenous microenvironments where tumor cells are often exposed to metabolic stress (e.g., hypoxia due to poor blood supply). Such environments select for tumor cells that can adapt metabolically to survive, while other cells fail to adapt and undergo cell death. The survival of cells through periods of hypoxia can promote chemoresistance and metastasis (1). Thus, it is critical that we develop therapeutic strategies to enhance metabolic-stress-induced tumor cell death. One promising strategy is the modulation of lysine acetylation pathways by HDAC inhibitors that potently pro- mote cell death in response to various stimuli, including hypoxia/glucose withdrawal. Given the relatively non-specific nature of chemical HDAC inhibitors, the precise acetylation-regulating enzymes and pathways that govern cell death in these settings have yet to be fully elucidated. Our goal is to identify the cellular factors that link acetylation to cell death in response to hypoxia and other metabolic stresses, with the hope that such factors could be exploited therapeutically in cancer. Previous studies have implicated protein lysine acetylation in the coordination of cellular metabolism to the available nutrient supply (2). In line with this idea, our preliminary data suggest that lysine acetylation pathways dictate whether breast tumor cells survive (through metabolic adaptation) or die in response to hypoxia and glucose deprivation. Moreover, we have observed that general increases in protein lysine acetylation precede the activation of pro-apoptotic caspases in response to these stresses. In addition, our proteomics efforts have shown that breast tumors that are sensitive to hypoxia/glucose withdrawal exhibit significant increases in acetylation across the proteome, whereas resistant cells show very little change. Together, our data suggest that lysine acetylation pathways play a role in metabolic adaption and survival under conditions of hypoxia/glucose withdrawal. We are currently using an RNAi approach to target all known deacetylases, acetyl-transferases, and metabolic enzymes that modulate acetylation (e.g., acetyl-CoA synthetase) in order to identify the specific acetylation-regulating factors that govern tumor cell susceptibility to metabolic stress.

Paul Chidsey, Brigham Young University Chemistry and Biochemistry It has been reported that an estimated 11% of women in the population have undiagnosed endometriosis, emphasizing the need for early detection tests and treatment options. Diagnosis is typically determined through an analysis of symptoms, including painful menstrual cycles, pain in the lower abdomen, and prolonged menstrual cramping. Diagnosis is further confirmed through invasive procedures such as transvaginal ultrasound and pelvic laparoscopy. Serum proteomic studies in which small biomolecules and peptides are analyzed for biological significance in endometriosis cases and controls can lead to the discovery of novel methods whereby the disease is detected and eventually treated earlier in development without the need of invasive procedures. Comparative analysis of cases and controls through mass spectroscopy has led to the discovery of novel biomarkers capable of correctly identifying individuals with endometriosis. Further pursuing this study will allow for a greater understanding of the genesis of the disease, eventually uncovering the mechanism whereby endometriosis develops.

Devon Blake, Brigham Young University Chemistry and Biochemistry G proteins play a vital role in cellular signaling. It has recently been shown that the nascent G polypeptide requires the assistance of phosducin-like protein 1 (PhLP1) for proper folding and formation of the G beta gamma dimer. This mechanism is derived from cell culture experiments and structural data, but until now had yet to be tested in vivo. We tested PhLP1 function in vivo using retinal rod photoreceptor-specific PhLP1 conditional knockout mice. Electroretinogram analyses of these mice showed a dramatic decrease in light sensitivity of rod photoreceptors. Consistent with this finding, the expression of all subunits of the photoreceptor G protein was reduced by 80%. This decrease was reflected in a similar decrease in the amount of G beta gamma dimers. All of these in vivo results are consistent with the hypothesis that PhLP1 is required for G beta gamma assembly and G protein signaling.

Brennan Young, Utah State University Geology Thermal springs in northern Utah and southeastern Idaho mostly lie near active or inactive Basin-and-Range normal faults. They are dynamic systems, and the character of some has changed drastically since work as early as the 1980’s (Blackett and Wakefield, 2002; IDWR, 2001). We examined and sampled 60 thermal springs and most samples met criteria for cation geothermometers, or mathematical-geochemical tools used to estimate the maximum temperature of hydrothermal reservoirs. Of the 60 springs, 51 met criteria for the Na-K-Ca geothermometer and the remaining nine springs did not meet the criteria for the K-Mg, Na-K, Na-K-Ca, or Na-K-Ca-Mg cation geothermometers used in this project (Fournier and Truesdell, 1973; Fournier and Potter, 1979; Giggenbach, 1988). Of those 51 springs, only one is considered to be in partial equilibrium with the thermal reservoir, and estimates a reservoir temperature of 79°C (Giggenbach, 1988). Though the majority of springs exhibit a chemical signature of having mixed with shallow groundwater (Giggenbach, 1988), the Na-K-Ca geothermometer gives the most reliable results for springs in northern Utah and southeastern Idaho, but only for springs with surface temperatures exceeding 30°C and with greater than 1000 ppm total dissolved solids (TDS). Geothermometer results for these springs yield reservoir temperature estimates between 193 and 249°C.

Daniel Gray, Utah Valley University Physics Mini black holes (BH) of various mass could be left over in space from the early expansion Big Bang phase (so called primordial BHs). As a result of interaction of those BHs with interstellar hydrogen they could form a bound system with an electron or a proton (or both). What would such system look like? Would it be stable, metastable, or would BH quickly consume the orbiting particle? How much is life time of such “gravitational atom”? If such system is stable then what is the size of it; how much is the bonding energy of its ground state (=ionization potential energy) and how much are the energies of its exited states? Are those atoms “gravitational atoms” observable? What other properties do they have? Based on known physics we try to analyze the behavior of such exotic systems and answer the above questions for black holes of various masses.

Ryan Smith, Brigham Young University Geological Sciences Bhutan, a remote country in the Himalayas, has an underdeveloped economy that relies heavily on hydro-electric power and agriculture. Glacial lake outburst floods, or GLOFs, threaten both of these sectors of their economy. More importantly, they threaten human lives. In this study, I will estimate the increase in volume of the most rapidly growing glacial lakes in the Bhutanese Himalayas and investigate potential causes of their growth. In addition, I will develop a simple model to simulate the flooding effects of a GLOF on downstream cropland and villages.

Samuel Leventhal, University of Utah Physics The uncertainty existing within the scientific community as to why quantum mechanics (QM) behaves as it does comes from the fact there exists no mathematically sound approach for deriving the postulates of QM. It is the purpose of our research to present a derivation for the postulates of QM through the theory of Scale Relativity (SR), followed by a search for physical signatures of SR in the mechanics of celestial bodies. The construction of SR is based on an extension of the relativity principle to scale transformations coupled with a loss of differentiability. Our first paper presents the derivation of QM through scale relativity. During the SR derivation we also show fundamental qualities of QM, such as the presence of complex numbers in state functions. Lastly, the seemingly unrelated behaviors between relativity and quantum phenomena are shown a single mathematical formulation, only to change form due to scale. The new resolution variable within the adapted Schrodinger equation allows it to become applicable to macroscopic scales allowing us to look at large scale mechanics for signs of SR. Gravitation being scale invariant leads it to be a perfect candidate for experimental purposes. Our second paper investigates whether or not celestial bodies, formed by chaotic gravitational structuring, obey the properties of a Schrodinger equation dependent on the Keplerian potential. If so SR implies solar systems would form along probability distributions predicted by the square magnitude of the Schrodinger-Keplerian wave equation. In theory a planets probability distribution would depend on discrete variables, denoted orbital rank, n=n. In search for SR it is sufficient to see if planets tend to have orbital ranks near integer values. We start by calculating the orbital ranks within various solar systems, followed by testing whether the accumulation of planets’ rank near integer values is a probable event. To test this we take the squared difference between the calculated rank and the nearest integer. As a result we are able to test how likely orbital structuring will be discrete. Our results show a strong certainty that orbital rank is likely to accumulate near integer values.

Sally Hansen, Utah Valley University Chemistry Cytochrome c oxidase (CcO) or complex IV is the terminal component of the electron transport chain. In eukaryotic organisms, CcO is composed of 12-13 subunits. The core of eukaryotic CcO contains three mitochondrially encoded subunits that comprise the catalytic core of the complex and several gene products encoded for by the nucleus (1). Essential to the redox function of CcO are several critical cofactors: two hemes and two copper centers (2). The crystal structure of CcO has led us to several insights about its structural components and catalytic activity (3). However, a large set of nuclear gene products are essential for CcO activity that are not part of the structural machinery of the complex (4,5). These components have been implicated in various stages of CcO assembly including, heme processing and insertion (6), CuA and CuB site delivery and insertion (7), subunit processing and subunit assembly (8,9). Among them are well characterized CcO assembly factors that involve the biogenesis of the CuA and CuB sites in CcO. Sco I, Cox17, Cox 11 and Cox23 are all essential to CcO activity and have properties that appear to be critical to the maturation of the CuA and CuB sites(10-13). Cmc4 appears to be involved in cytochrome c oxidase biogenesis. Peroxide phenotypes have been linked to cytochrome c oxidase assembly (14). Saccharomyces cerevisiae strains lacking CMC4 were found to exhibit peroxide resistance when compared wild type parental stains. Resistance was seen in liquid culture and in media containing glucose and glycerol. These results may indicate that cytochrome c oxidase assembly is altered in CMC4 deletion stains.

Natascha Knowlton, University of Utah Chemistry The chemical derivatization of oxide surfaces (silica, alumina, glass) is critical to the development of separation media, sensing surfaces, or biocompatible interfaces. Presently, there are few analytical methods that allow the detection and characterization of functionalized monolayers on these surfaces. Raman scattering spectroscopy can provide useful structural information in the form of vibrational spectra of molecules of interest, and it is compatible with oxide substrates. Raman scattering, however, is a very weak effect so that its application to detecting monolayers is challenging. In this work, two approaches to detecting and characterizing molecular layers on oxide surfaces with Raman spectroscopy are compared. First, gold colloidal nanoparticles are deposited onto the surface of interest, which enhance the Raman scattering near the gold surface by surface-plasmon resonance. This technique is suitable for ex situ analysis of monolayers on planar surfaces. Secondly, monomolecular layers can also be detected by Raman scattering on porous oxide supports such as alumina or silica without any optical enhancement due to the very high surface area of these materials. Detection in porous particles is compatible with in situ monitoring of surface derivatization reactions. These two methods are compared for monitoring of reactions of silane-coupling agents and their subsequent functional group transformations on glass and silica surfaces.

Alyssa Brown, Southern Utah University Physical Science Coal Creek is a perennial stream that runs through Cedar City, Utah and drains into Rush Lake. The basin is a closed basin, meaning that most of the surface water will eventually become ground water, the main source of drinking water for Cedar City. Because of the increase of urbanization of this region in par- ticular, there is a higher probability of pollutants entering the water source and greatly affecting the quality of the drinking water. Most pollutants are characterized as nonpoint source pollution, which is defined by the Environmental Protection Agency (EPA) as, “land runoff, precipitation, atmospheric deposition, drainage, seepage or hydrologic modification” and is the leading cause of water quality problems (Environmental Protection Agency, 2012). Common sources of land runoff, as defined by the EPA, include septic waste, lawn and garden fertilizers, improperly disposed chemicals, automobile fluids, vehicle emissions, and road deicers (Environmental Protection Agency, 2012). In order to characterize the pollutants found in samples and determine the concentration of ions of interest, ion chromatography was used. By determining the identity and concentrations of particular ions, the presence of nonpoint pollution, and the source, may be determined. This study may lead to better indications of where major sources of drinking water pollutants are originating, illustrating the effect that urbanization and rapid population growth have on the quality of both surface and ground water. This will allow better characterization of pollutants and pollution sources in the future.

Joshua Jeffs, Utah Valley University Chemistry The electron transport chain (ETC) is a system within a cell that couples electron transfer between a donor and a receptor. The ETC is made up of several components, specifically: complexes one through four, a coenzyme Q, and a cytochrome complex. Cytochrome C oxidase (CcO), also known as complex IV, uses electrons and H_ ions to reduce molecular oxygen to water. CcO is made up of several subunits or proteins that are responsible for the function of CcO. The creation of CcO involves multiple steps that include many different gene products or proteins. (3) Of these proteins several are from a specific type of family called cysteine-X _-cysteine motifs (twin CX_C). The cysteine residues in the cysteine pairs are each spaced by nine residues. The best characterized protein of this group is Cox17, a copper-binding protein that plays a role in copper transfer to CcO. There are 14 potential proteins that are twin-Cx_C motifs (1). There were four knock out strains that showed resistance when plated on YPD with varying concentrations of hydrogen peroxide: 0.010%, 0.014%, 0.018%, and 0.022%. Strains lacking CMC4, MIC14, MIC17, and PET191 all showed resistance to hydrogen peroxide compared to the parental strain. Strains lacking MDM35 and COX23 showed sensitivity to hydrogen peroxide. These result may indicate a tie to impaired or incomplete cytochrome c oxidase assembly.

Rachel Nydegger, Utah State University Physics Multi-messenger astronomy employs both electromagnetic and gravitational-wave detectors to paint a richer picture of celestial objects, providing more depth and information. The interferometers utilized for gravitational-wave observations receive input from very broad fields of view on the sky, typically a few square degrees. To have simultaneous electromagnetic observations (typically less than one square degree) requires innovative techniques for the telescopes to find the origin of radiation. One idea is to “tile” the view of the interferometer, using multiple telescopes to simultaneously point at different areas of the field to observe the source. One difficulty of this observing paradigm is distinguishing random electromagnetic variable sources from a gravitational-wave counterpart. To better understand this problem, this project repeatedly observes a single field on the sky. Each observation is analyzed to count the number of sources that appear in the field as a function of brightness. Repeating this process over time will yield the frequency of random optical transients, as well as characterize the population and brightness distribution of variables in the field. Future work will extend this observation campaign to cover different galactic latitudes.

Jeremy Redd, Utah Valley University Physics Future space propulsion systems will likely use annihilation of matter and antimatter in propulsion system. Annihilation of matter and antimatter is not only the energy source of ultimate density 9×10^16 J/kg but also allows to utilize ultimate exhaust speed the speed of light c thus potentially allows to accelerate a payload to ultrarelativistic velocities. Such velocities make interstellar and even intergalactic travel possible in the lifetime of one generation only (20-30 years). In our presentation we discuss advantages and disadvantages of interstellar travel with relativistic and ultra-relativistic velocities. Using relativistic Tsiolkovsky rocket equation we also discuss the feasibility of achieving relativistic velocities with annihilation powered photon engine and technical challenges to build such engine.

Kelby Peterson, Utah State University Physics The State of Utah Space Environment & Contamination Study (SUSpECS) experiment flown on the Materials International Space Station Experiment 6 (MISSE-6) was an experiment designed to examine the consequences of the space environment on various materials used in space-component design. SUSpECS was comprised of approximately 180 samples that were suspended from the side of the International Space Station (ISS) for 18 months and returned to allow for pre- and post-flight comparisons. The sample with the most evident changes was a thin film of polyethylene terephthalate (PET) MylarTM coated with Vapor Deposited Aluminum (VDA). The post-flight analysis showed evidence of atomic oxygen erosion of the VDA layer, UV-induced discoloration of the polymer, and a crater created by a micrometeoroid impact. This presentation focuses on the UV-induced discoloration and laboratory tests to simulate these effects. The UV tests expose similar polymers to varying intensities of vacuum UV radiation from deuterium lamps over a condensed time span and quantify the discoloration of the polymers through comparison of the UV/Vis/NIR reflection spectra. The results from the UV simulation are used to determine the approximate time period of the UV exposure for the SUSpECS sample and in turn the erosion rate of the VDA layer.

Cathy Crawford, Utah State University Chemistry and Biochemistry In the spirit of many chemistry instructors’ longstanding interest in making teaching labs less “cookbook-like” and more research-driven, we recently restructured our second-semester sophomore organic chemistry lab to include a synthesis project that was chosen, designed, and carried out by students. Students were given the incentive of co-authorship on any publications resulting from their work. This led to the development of total syntheses of JBIR-94 and JBIR-125, new antioxidative/anticancer compounds with radical-scavenging potencies comparable to those of a-tocopherol, the active constituent in Vitamin E. Our presentation will summarize our progress and findings, and includes our progress on bioactivity studies conducted on the JBIR’s and their synthetic precursors.

Alyssa Brown, Southern Utah University Physical Science It has been long debated whether early astronomers could truly see any detail during their first observation and rough sketches of the satellites of Jupiter. Many have argued against the accuracy and validity of such drawings, claiming the lack of technological advance led to rough hewn and mediocre drawings with little evidence of these individuals having truly seen these satellites. Through our research, we hope to prove validity in those early sketches based on current knowledge. By converting the dates and times each early sketch was created into Julian Calendar days, then using the date obtained to calculate the position of each individual satellite of Jupiter, as well as the face that was approximately facing Earth at the time the sketch was made, we can compare current images to those previously obtained sketches. By analyzing the sketches for determining features as well as the relative location of those features in relation to their approximate location on the satellite face the astronomer was most likely observing, we can either validate or disclaim these early sketches. This experiment will provide beneficial insight into the accuracy of primitive sketches made centuries before more detailed information was discovered about the celestial bodies that continue to fascinate us. The information gained from this experiment may even lend a greater knowledge and understanding of how to study these celestial bodies, since if the information presented by these early sketches were accurate, we could potentially reevaluate the manner in which we currently conduct our present observation.

David Pease, Utah Valley University Physics Transition regions to higher resonant modes of a bottle-shaped thermoacoustic prime mover (neck: 5.39 cm long, 1.91 cm ID; variable cavity with a sliding piston: up to 38 cm long, 4.76 ID) were studied. As the piston is extended, lengthening the cavity, starting from the neck, a transition of the dominant frequency from the fundamental to the first overtone occurs. However, when the length is then shortened, transition back to the first mode does occur at the same piston position, revealing hysteresis. Within the window of hysteresis for the cavity length, either state of the fundamental or first overtone is possible. Transition regions to higher modes continue as the length of the cavity is increased. The position and width of the hysteresis was studied for the first two transition regions as a function of input power and stack volume filling factor. Input powers studied were between 12.0 and 16.5 W and volume filling factors for the stack were about 3.0, 3.7 and 4.9%. The transition regions occurred with cavity lengths between 12.6 and 14.0 cm for the first transition and between 25.0 and 27.8 cm for the second transition. Preliminary results indicate that the transition region occurs shallower in the cavity and the hysteresis widens as the input power is increased. The hysteresis is wider for the second transition region. Decreasing the stack mass causes an increase of the hysteresis width, but has no strong effect on the hysteresis depth.

Ben LaRiviere, Utah State University Geology The DOE-funded HotSpot Project out of Utah State University has collected a more than mile-deep core from the central Snake River Plain, Idaho, to study the geologic history of the area. The core consists mostly of volcanic basalt, however 16 sediment layers have been identified and sampled between the basalt-flow layers. These layers of sediment are the key to understanding environmental conditions on the Snake River Plain between basalt flows. The sediment was sampled in 25cm increments and the grain size of the sediments were examined in a laser particle size analyzer to better understand depositional conditions on the snake river during the past 5 million years. The analysis revealed that the majority of the sediment was deposited as windblown silt with several fluvial deposits.

Kent Hartley, Utah State University Physics Faraday cups provide a simple and efficient apparatus to measure the absolute magnitude of charge particle fluxes, and with the addition of a retarding field analyzer and defining apertures the capability to determine the energy and angular distributions of the fluxes. Through careful design of the electron optics, a Faraday cup can be tailored to meet specific requirements for detector size, minimum detectable flux, collection efficiency, absolute accuracy, energy discrimination, and angular resolution. This work explores design concepts through electric field and charged particle trajectory simulations, theoretical analysis, and evaluation of experimental prototypes to develop compact, high efficiency Faraday cups capable of a range of energy and angular resolutions. The designs rely on high efficiency Faraday cups coupled with grid-free Einzel lens energy analyzers for nearly energy-independent determination of absolute fluxes. We also review specific designs and applications of these Faraday cup detectors to electron emission and transport studies, spacecraft charging applications, and electron beam characterization measurements done in conjunction with various projects conducted by the Materials Physics Group.

Beau Hilton, Brigham Young University Physics/Acoustics The Udu drum, sometimes called the water pot drum, is a traditional Nigerian instrument. Musicians who play the Udu exploit its aerophone and idiophone resonances. This paper will discuss an electrical equivalent circuit model for the Udu Utar, a specific type of Udu, to predict the low frequency aerophone resonances and scanning laser vibrometer measurements to determine the mode shapes of the dominant idiophone resonances. These analyses not only provide an understanding of the unique sound of the Udu instrument but may also be used by instrument designers to create instruments with resonance frequencies at traditional musical intervals for the various tones produced and to create musical harmonic ratios.

Joseph Jensen, Utah State University Physics The earths ionosphere is very important in our everyday life. During large solar flares the ionosphere expands to the point of disrupting communications from GPS, military, and commercial communications satellites, and even radio blackouts can occur. The EVE instrument on the SDO satellite has given unprecedented spectral resolution for the Extreme Ultraviolet (EUV) spectrum with a time cadence of 10 seconds. This has made it possible to analyze flare spectra as never before. Using the Time Dependant Ionospheric Model (TDIM) we have input this new spectral data for large solar flares and analyzed the effect on the ionosphere. We take as a test case the X1.6 flare on March 9, 2011. Even this minor X-class provides insight into how the ionospheric layers respond differently to solar flares.

Jacob Wright, Utah Valley University Physics Dissonant overtones of closed bottle-shaped thermoacoustic prime movers are discussed. The resonator consists of two concentric cylinders with differing cross-sectional areas, closed at the outer ends. The condition for resonance results in a transcendental equation, which is solved numerically. The neck and cavity behave as coupled resonators, where the neck is a quarter-wave resonator and the cavity is a half-wave resonator. A variable cylindrical cavity with a sliding piston was constructed to study the nature of the device as the cavity length is varied. The stack is located in the neck region and the length and inner diameter of the neck are 5.39 and 1.91 cm, respectively. The inner diameter of the cavity is 4.76 cm and has a maximum length of 38 cm. The dominant mode of operation depends on the length of the cavity, favoring successively higher modes as the cavity length increases. The volume filling factor of the stack material was varied from 2 to 5% to determine whether the amount of stack material affects the transitions. These filling factors were selected to yield hydraulic radii comparable to the thermal penetration depth for the highest and lowest possible fundamental frequencies of the system. The transition to higher modes occurs roughly where the higher mode overlaps with the fundamental frequency of the neck region, and is independent of the stack filling factor. With the given dimensions, three transitions to higher modes were observed, with frequencies consistent with the model.

Michael Strange, Utah State University Geology For the past century, the standard technique used to interpret soft-tissue preservation in the fossil record has been the camera lucida drawing. A new technique called False Color Treatment (FCT), which uses digital photography and photo manipulation, shows an increased ability to not only interpret soft-tissue features but also identify trace amounts. Hyolithids from the Cambrian of northern Utah were used to test the capabilities of FCT. Results were then compared to camera lucida drawings of the same specimens. Comparisons show the camera lucida drawings missed areas of soft-tissue that FCT found. Depending on the specimen, and the type of preservation, this disparity in interpretations can increase or decrease. Hyolithid specimens from the Spence Shale show an odd form of Burgess Shale Type (BST) preservation which makes them particularly well suited for FCT manipulation. Overall, False Color Treatment provides an informative and aesthetic method for interpreting soft-tissue fossils with BST-like preservation.

Jordan Roberts, University of Utah Political Science I explore the tragic collision between individual self-determination and collective self-determination. While the conflict between these two ideals exists in many forms throughout political life, I focus on an international manifestation of this collision: the conflict between national sovereignty (predicated on collective self-determination) and international human rights (predicated on individual self-determination). There are perhaps no two international values more acclaimed, and no two values that clash as intensely; to allow for sovereignty means to allow for human rights abuses and to intervene in the name of human rights means to deny sovereignty. Eschewing traditional political lenses, I employ a tragic framework that 1) allows fuller engagement with the conflict and 2) avoids the pitfalls of the traditional lenses, including one-sidedness (which fuels the continuation of the conflict) and detachment (which allows for inaction). I draw on Sophocles’ Antigone, interpreting the title character as an embodiment of individual self-determination and Creon as an embodiment of collective self-determination. Furthermore, I argue that prominent attempts at finding a compromise between the two forces caught in this tragic collision, exemplified by the emerging international norm of Responsibility to Protect (R2P), are blind to the collision’s inherently tragic nature, and thus subvert one or both of the values at stake. I also address how this tragic blindness of notable theorists working on questions concerning human rights and sovereignty reproduces the blindness of another Sophoclean character: Oedipus. While tragic conflicts do not lend themselves to neat and tidy outcomes, a tragic framework embraces the conflict, instead of sidestepping it, and works towards an ambiguous, unhappy solution.

Kevin Korous, University of Utah Psychology The goal of this study was to explore if participation in different types of activities was related to the development of an internal locus of control in middle childhood. It was hypothesized that children who participated in more activities would have more of an internal locus of control than children who participated in fewer activities. Participants consisted of 45 adolescent boys and 99 adolescent girls (M = 10, SD = 1.34). Parents were asked to tell us about the activities their child participated in. The listed activities were grouped into four categories based on prior research: 1) sports based activities; 2) school based activities; 3) arts based activities; and community based activities (Barber, Abbott, Blomfield, & Eccles, 2009). To measure locus of control, participants were asked to tell us why a situation involving conflict with a peer occurred and what he/she would do. Then the narratives were coded for locus of control using a five-point scale. There was a significant difference in locus of control by story, Wilk’s A = .348, F(2, 143) = 37.64, p < .01, partial eta2 =.348. Participants were significantly more likely to report that the act of overt aggression was an event s/he had control over and could resolve independently whereas participants reported that the act of relational aggression was more externally driven resulting in less control over the situation, t(141) = -4.59, p < .01, mean difference = .123. Additionally, the participants reported a lower sense of control over the breaking of a social norm by a peer than they did in response to the acts of overt and relational aggression, t(141) = -4.093, p < .01, mean difference = .108 and t(141) = -8.672, p < .01, mean difference = .115, respectively. There was only one significant correlation among the different types of activities and the participants’ scores on locus of control. Children who participated in more arts based activities demonstrated more of an internal locus of control in response to a peer violating a social norm than children who participated in fewer arts based activities, r(142) = -.234, p < .01.

Sasha Trae, Dixie State University Communication This research critiques prevailing economic, political, and social discourses that create or uphold disadvantage, inequity, and oppression against women. Using multiple Critical Discourse Analysis tools, such as, lexical suppression and absence and representational strategies, this researcher will examine activist, political, and socio-cultural discourse, including Take Back The Night, to expose underlying ideology. This paper analyzes ideological functions of these and other constructions identified in the discourse. This researcher will illustrate how the analyzed discourse shapes our reality that the ownership of women’s equality and safety are in the hands of men. Additionally, this researcher will unveil the ideological suppression and absence of the perpetrator; consequently, twenty-first century public discourse places the responsibility in the hands of women to prevent and address violence against women, the victims. Further, this researcher will demonstrate how the revealed ideologies indicate that violence against women is random or unstoppable; thus, setting up women to continue being integrated into a system that is hostile to them. Moreover, the breadth of this ideology indicates that every society within the nations of our world declare that women are a subset of humanity, and that it is men who get to resist relinquishing this equality while women expend their efforts to obtain it. This paper concludes that violence against women is part of an economic and political system that has been codified and written into the laws of nations; therefore, creating and perpetuating the very structures responsible for the violent climate that we fear and live in.

Marlee Olsen, Snow College Psychology This study focuses on how college students interpret and understand new knowledge. Participants will be answering a number of questions via survey about their personal beliefs such as religion, reliable sources of knowledge, and other possible mitigating factors. After reviewing existing research, we found studies being done over long-term acceptance of beliefs, and also studies of the affects on understanding and acceptance of new beliefs after exposure to relative information. However as we reviewed the literature we found lacking information specifically regarding whether college students, when exposed to new concepts, accept the information before understanding it, or postpone acceptance until further understanding. The survey will be given out to students in different geographic regions across the nation to obtain various religious backgrounds, race, gender, and geographic background. We project to find a correlation between religiosity and the rate of acceptance of new beliefs before understanding. Other mitigating factors such as ratings for source of knowledge and geographic background are expected to also have affects. Results will be discussed.