2014 Abstracts
Perceptions of Evolution: Insights from interviews
Tanner Mortimer, Utah Valley University Social and Behavioral Sciences Surveys show that nearly half of all Americans reject evolution as an explanation of the origin and diversity of life on Earth, especially when concerning human evolution. (Gallup 2007). Furthermore, there is a correlation between the rejections of evolutionary science with a belief in a Christian God-creator (Gallup 2007).
Identifying Those At-Risk for Suicide via Machine Learning
Michael Christensen, Brigham Young University Social and Behavioral Sciences Suicide is a major problem for students in Utah middle and high schools. Since adolescents spend a large portion of their time on social media like Facebook and Twitter, there is a wealth of information we can learn about their personalities, moods, and interests by exploring their online interactions with others and specifically the statuses and messages they post publicly. We have created a Facebook app to mine this data and report the mood of a logged-in user’s entire network based on the individual classification of community members’ posts. We contribute to the Public Health field by aggregating suicide-risk factors and facilitating intervention, the motivation being to help others better identify and help those who are at-risk for suicide based on their online behavior. We contribute to the Computer Science field by creating a machine learning algorithm that can classify text into one of several fine-grained mood categories, learning to identify more than just positive or negative sentiment. In addition, our algorithm has the ability to update online by receiving feedback from the users on how well or poorly it classified the text of their friends’ posts. We describe our algorithm and report on preliminary results about its performance on real-world data.
Developing a Typology of Neighborhood-Level Water Usage Along the Wasatch Range Metropolitan Area
Zack Bjerregaard, Weber State University Social and Behavioral Sciences The research presented here will lay the groundwork for a larger project as part of iUTAH that will examine the interrelationships and feedbacks among hydroclimate and the ecological and human aspects of urban and montane landscapes in the Wasatch Range Metropolitan Area (WRMA). To assess how human systems and urban development patterns influence water sustainability, we developed a typology of neighborhoods in the WRMA based on sociodemographic and climate variables and built environment characteristics that previously have been found to affect water system dynamics. Using GIS and statistical analysis programs, variables were aggregated to census block groups (CBGs), which we determined were a satisfactory proxy for neighborhoods in most urban areas. Previous studies show that neighborhoods are an important level of measurement because of their influence on individuals’ behaviors. Only CBGs that had a recalculated population density of at least 50 people per square mile after subtracting areas of water and/or federally-owned land were included. A statistical factor/cluster analysis was performed on these variables, which returned a typology of neighborhoods and their spatial distribution based on water usage. The typology will be used by other members of the project to target a select number of each neighborhood type, where instrumentation and further data collection will be implemented to examine the impacts of urban development patterns on water sustainability and the wider ecological and physical hydroclimate.
University Student’s Perceptions of Bisexual Behavior
Brooke Bradford, Utah Valley University Social and Behavioral Sciences Research in the area of sexuality indicates that females tend to be more flexible in their sexual behaviors than males.(Baumeister, 2000) Studies also seem to indicate that there is a more permissive and accepting attitude towards women’s bisexual behaviors than towards men’s bisexual behaviors(Lippa, 2006; Savin-Williams, 2006) The present experiment was created in order to measure the perceptions of bisexual behavior held by Utah Valley University students. One hundred students were asked to read brief descriptions of similar sexual behaviors participated in by men and women. Participants were asked to rate these sexual behaviors on a scale and indicate if they perceive the behavior as heterosexual, questioning, bi-curious, bisexual or homosexual. The participants were then asked to rate behaviors on a scale of acceptability as well as a scale of commonality. The questions consist of similar behaviors being engaged in by males and females in order to test for changes in perceptions of the sexual activity occur based on the gender of the actor in the scenario. It is hypothesized that the results of these surveys will support current research in this area and confirm that the scenarios featuring females will be rated as more acceptable, common and placed in the bisexual categories.
Relationship Anxiety Test Project
Branden Nuttall, Brigham Young University Social and Behavioral Sciences The Relationship Anxiety Test was developed to find a way to measure the level of Anxiety in Latter-day Saint (LDS) college aged individuals who are currently searching for a future companion. Research has suggested that relationship anxiety was higher in individuals who are currently looking for a future spouse. The goal of our test was to measure this anxiety in LDS individuals because it is believed that these individuals are under more pressure to find a spouse. The test was formatted by using a set of questions to measure the anxiety using two domains cognitive, and behavioral. The test was administered using Qualtrics and was distributed through email and Facebook. The results of the test are currently being measured and will be available within the next month.
Denmark and Guernsey during World War II: why individual and group responses differ under the same negative circumstances.
Anthony Hoffman, Utah Valley University Social and Behavioral Sciences During World War II, the Germans occupied two places that have often been overlooked in the history books since: Guernsey in the Channel Islands and the nation of Denmark. Both are strikingly similar in terms of World War II history and overall treatment by the Germans. In contrast, both are strikingly dissimilar in terms of reaction to the Germans, treatment of each other, treatment of other minority groups within their own countries, etc. It is the similarity that provides the ability for these two places to be compared, which in turn provides a context for the dissimilarity to be studied within. The bulk of information for this research comes from the written histories about those countries during World War II, as well as available individual and personal accounts within each group such as diaries, histories, memoirs, etc. The framework that will be used for interpreting the dissimilarities will take a psychological/social psychological approach, drawing on works from researchers such as Milgram, Darley, Latane, and Shergill, to name a few. The focus of this research is centered on the following question: why do people in very similar circumstances have drastically different reactions? It is expected that this research will shed more light on the reasons for why one individual or group of people reacts one way under bad circumstances, while another individual or group under the same circumstances reacts differently. A better understanding of this phenomenon can help individuals, groups, and nations know how to best help those suffering in the world both today and in the future.
The Financial and Emotional Impact of Elemental Formula
Tammy Zundel, Utah Valley University Social and Behavioral Sciences Eosinophilic gastrointestinal diseases (EGID’s) are a family of digestive disorders that affects a patient’s physical, mental and social well-being. Because some patients are forced to eliminate all foods from their diet, many patients miss out on holiday meals, birthday cakes, and other social events. Patients with severe cases may depend on steroids and the strict use of medical nutrition therapy, such as elemental formula. Elemental formula describes a liquid diet that contains all the necessary nutrients for a complete diet made up of proteins broken down into their amino acid form, making it easier for the body to digest and absorb. Though elemental formula literally saves lives and is the most effective treatment used for those who have failed other treatment options, insurance companies are not required to cover its high costs. Families without insurance coverage are left struggling to pay for this prescribed treatment out-of-pocket. The purpose of this mixed methods study is to explore the financial and emotional costs associated with not having access to a prescribed treatment. Data was collected during an in person interview and the administration of a survey containing standard demographic questions related to age, gender, marriage, income, work status, and education level. Also included were closed-ended questions related to the patient’s diagnosis, elemental formula use, and amount of money spent out of pocket for non-covered medical needs. Several open-ended questions focusing on the financial and emotional impact associated with not having access to elemental formula as a prescribed treatment were included. The results will be used to educate health care providers and promote further research into the issue.
Restoring Life & Limb, a Service Expedition for Guatemalan Amputees
Jonathan Latham, Utah Valley University Social and Behavioral Sciences Introduction: Guatemala has been subject to dictatorial regimes, crimes against humanity, civil war, and genocide. There are nearly 30 million people in need of prosthetics worldwide; two percent currently have access to appropriate prosthetic care. To combat this debilitating issue in Guatemala, Utah Valley University’s Mobility Mission (UVU-MM) travels once a year to manufacture high-quality, low-cost prosthetic legs for individuals in need. For two weeks, Julio Fuentes, Certified Prosthetist & Orthotics (CPO) lends his clinic, equipment, time, and expertise to UVU-MM. The goal of this research is to identify patterns, themes, concerns, and trends among amputees to secure their future well-being.
Political Polarization in Youth Voters
Morgan Williams, Brigham Young University Social and Behavioral Sciences My research intends to answer the question, are the youth today more polarized than they were 25 years ago, and does increased polarization in youth attitudes lead to a higher percentage turnout among youth voters. This is an important area to research because elected officials have never been more polarized on both sides of the ideological scale. It is important to examine possible causes for this polarization, one of which is that these elected officials are catering to the attitudes of the emerging youth voters, causing them to take more polarized stances. Polarization in this research will mean that the divide between the two core ideologies, liberal and conservative has grown wider. This will be measured by looking at an individual’s placement on the ideological scale, if they are liberal learning they will be classified and liberal and the same applies for the conservatives. I will then compare these two groups and there stance on certain issues, such as government spending and abortion, overtime to see if the divide has grown larger. I will be using the American National Election Studies data set to look at youth voting patterns and attitudes from the 1988 presidential election until the 2012 presidential election. I will be defining a youth voter as a voter between the age of 18-29, meaning they could have voted in no more than 2 presidential elections. This research will be done in January and February of 2014, therefore the results of this research are not currently available. I hypothesize that the polarization in the youth voting bloc has not grown wider over time, but fluctuated throughout the years. I also hypothesize that years with a higher level of polarization will lead to a higher turnout among the youth.
Prenatal maternal stress in relations to the brain development of the fetus
Chauntelle Gates, Dixie State University Social and Behavioral Sciences Prenatal maternal stress (PNMS) can affect the brain development of the fetus and we know early experiences, even during gestation, shape the way our brain is developed. Since the brain growth of the fetus is rapid, any stressful situation can alter the rate at which the brain develops resulting in an under developed brain at the time of birth. This paper focuses on potential risks associated with prenatal maternal stress to the developing brain throughout gestation and preventive measures to reduce risk. Prenatal care is used throughout the world in a preventive manner to ensure optimum health and welfare of the mother and her baby, throughout gestation. Prenatal care is imperative and should take place during the first trimester to prevent potential risks to the fetus. It detects early signs of abnormalities in the infant, benefiting the mothers’ overall health. Mothers who take advantage of prenatal care, especially when PNMS occurs, have better birth outcomes and overall the brain development of the fetus is less effected. Other life situations could affect the brain development of the fetus but this paper will only focus on the effects PNMS has on the brain.
Paving the Road Not (Yet) Taken: A Critical Analysis of Two Roadmaps for Kashmiri Democracy
Pratik Raghu, Westminster College Social and Behavioral Sciences Divided between India and Pakistan in multiple senses, Kashmir is home to the one of the world’s oldest yet least discussed civil conflicts. India and Pakistan continue to defend their claims to Kashmiri land, but most political thinkers agree that establishing an independent democratic state is the only way to ensure long term politico-economic stability in South Asia. However, what should this democracy look like?
Nazi Invasion of Russia during World War II
Helen Jones, Weber State University Social and Behavioral Sciences The events of the past often colors how observers interpret current events. Past interaction between two countries sometimes influences current events as well. Recently reported stories concerning United States agents spying on German Chancellor Angela Merkel through information provided by Edward Snowden (Cohen, 2013) from his exile in Russia impact three nations. The release of information concerning American actions regarding German chancellor by Russian exile Edward Snowden could be a link between current events and the trust issues of the past. The relationship between the United States and Germany could resolve in time because people are aware of the issue. The relationship between Germany and Russia relative to the information Snowden provided could also be difficult as Germany evaluates whether it can trust Russian leaders who granted Snowden exile. The interaction between German and Russian leaders prior to and during World War II had a trust issue. The pact between Germany and Russia in 1939 was an attempt to keep the battle focused on one front for the Nazis. For Russian leader, Josef Stalin, the pact was a way to delay Russian force deployment in the event of world war. The Nazi invasion of Russia in June 1941 violated the trust Josef Stalin placed in the pact signed with Adolph Hitler. This misplaced trust blurred the vision of the Russian leader when advised of the Nazi presence on the western Russian border. Russia had many resources Hitler wanted bad enough to break the treaty with Stalin. The experience between Germany and Russia during World War II illustrate how important trust becomes between countries, leaders, and people. Tom Cohen, “Top Senator: Obama didn’t know of U.S. spying on German’s leader,” CNN, October 29, 2013, http://www.cnn.com/2013/10/28/politics/white-house-stopped-wiretaps/ (accessed 10-30-2013).
Understanding the Experience of Early Returned Missionaries
James Westwood, Utah Valley University Social and Behavioral Sciences The Church of Jesus Christ of Latter-day Saints expects young adult males to serve a religious mission, and gives young women the same option. Those who choose to serve, do so for two years if male, and 18 months if female. Occasionally, some return home prior to the full term of service due to unforeseen medical, mental health, or adjustment-related issues. Many who return early perceive themselves as failures, ostracized and unfairly judged. This phenomenological study explores the experiences of these young men, gains an understanding from their perspective, and provides helpful insight and understanding to church members, church leaders and clinicians who work with this population.
A Contemporary Assessment of Feminist Attitudes
Jay Winters, Brigham Young University Social and Behavioral Science The common stereotype of feminism has a negative connotation implying that feminist’s are simply radical women’s rights activists. The reality is that feminism is hard to define given its complexity and the range of issues it encompasses. A scale was developed in 1994 called the Attitudes Toward Feminism and the Women’s Movement (FWM), which sought to predict attitudes toward feminism (Fassinger, 1994). Many social psychologists see it as an effective way of predicting attitudes despite its age or lack of an emotional component. Our Assessment of Feminist Attitudes (AFA) scale was developed to include an emotional response component as well as provide a contemporary view of the ever-changing feminist movement. Our study is in the process of being assessed for statistically significant data. The effectiveness of the AFA in measuring feminist attitudes will be known in the coming weeks.
Research on the Relationship between the Police and the Muslim Population of Cambridge England
Madeleine Ary, Brigham Young University Social and Behavioral Sciences In 2010 I conducted research in the city of Cambridge England on the relationship between the Muslims of Cambridge and the police of the same city. I conducted this research primarily through single interviews and data analysis from the United Kingdom in general and England specifically. From this research I discovered that the relationship between these two groups was maintained by frequent, mutual contact and trust. England at the time was experiencing a summer of rioting, much of which revolved around Islam. This may have increased the difficulty in such a faith group, authority relationship, however their efforts to maintain a positive relationship only intensified and there was little to no real disruption within the Cambridge Muslim community. My research demonstrates how such relationships can be effectively conducted even in otherwise tumultuous circumstances.
EMS Stress Model
Cassandra Southam, Utah Valley University Social and Behavioral Sciences Recruitment and retention are two of the most salient issues in emergency medical services (EMS) today. The National Association of State and regional EMS leaders, has twice identified recruitment and retention as the most important issues facing rural EMS agencies across the nation. The purpose of this study was to predict how Utah EMS personnel reached a point of wanting to resign using a stress model; value of job, self and other harm, spouse satisfaction, formal support as independent predictor variables. This data was obtained from an IRB approved statewide survey of all EMS personnel during the Spring of 2010. Of the 7,000 current EMS employees, 668 completed the survey, resulting in a 9.5 percent response rate. Results. The linear regression model indicated that the model explained 28 percent of the overall variance. A brief explanation of the findings indicates that all the direct paths were significant at the .05 level. The more they harmed themselves and others, the more they wanted to resign (Beta coefficient of .31). The higher their levels of Past Call-related Stress, the more they wanted to resign (.21). The higher their levels of spouse satisfaction, the more they wanted to resign (.07). The more they found value in their job, the less they wanted to resign ( -.18), And finally, the more they valued formal support from the debriefing team, the less they wanted to resign (-.10). Administrators and agency leaders can use these indicators to intervene when an EMS employee reaches a difficult point from the stresses and hardships of the job. Education, training, and available support can be very useful in preventing trained, experienced, and valued EMS employees from leaving the field. Local EMS directors and policymakers may find the results and study methodology useful toward designing and evaluating programs.
Negative Pressures and Adolescent Admission Experience in Outdoor Behavioral Treatment
Clinton Hardy, University of Utah Social and Behavioral Sciences Coercive treatment practices, while controversial, are commonly employed (by mental health professionals and parents) when admitting adolescents into outdoor behavioral healthcare (OBH; e.g., outdoor/wilderness therapy) and residential-based treatment settings. While coercive practices have been investigated in various adult treatment contexts, to my knowledge no study has examined coercive practices or pressures among adolescent treatments. As the first of its kind, my report investigates the relationship between adolescent-perceived coercive treatment pressures (i.e., negative pressures) and their affective reactions reported when entering OBH treatment. Negative pressures, or the perceptions of “threat” and “force” during admissions, are measured via the Negative Pressures Subscale (NPS) of the MacArthur Admission Experience Survey (AES). Affective reactions to entering treatment are measured via the Positive and Negative Affect Schedule – Expanded Form (PANAS-X). Although this study is still taking place, my interim analysis (N = 36, age range: 14-17) has so far demonstrated the following predicted relationships between negative pressures and affective reactions in OBH treatment admissions: An adolescent’s increased perception of negative pressures significantly correlates with (a) increased affective distress (r = .377, p = .037), (b) decreased affective positivity (r = -.61, p < .001), and (c) increased affective hostility (r = .464, p = .003). Therefore, significant medium to large correlational effect sizes are reasoned to be imminent. In recognizing that negative pressures might not only relate to an aversive admissions experience, but also negatively impact or delay positive treatment outcomes, future research is concluded to be essential.
Status quo bias and agent-external loss aversion in ballot wording
Ryan Hill, Brigham Young University Social and Behavioral Sciences We analyze the presence of two types of framing bias in ballot wordings that affect election outcomes: status quo bias and agent-external loss aversion. Both of these biases are studied extensively in behavioral economics and likely have salient impacts on initiative or proposition measures in state elections. Status quo bias is the tendency of a voter to be more likely to maintain a currently enacted policy rather than passing a new law. Agent-external loss aversion is the tendency for a voter to be more likely to grant a right to a minority population rather than vote to restrict a right. Both of these biases have had important impacts on the outcome of recent ballot initiatives especially on California Proposition 8 that failed to legalize the right of marriage for same-sex couples. We test the salience of these framing biases by conducting a nationwide survey experiment that randomly assigns different ballot wordings for the same policies across different survey respondents. The survey mimics a real voting situation and the randomization of questions ensures that we can identify the specific effect of each bias on the voting outcome. We analyze the treatment effects using difference of means and ordinary least squares analysis. We also extend our analysis to examine whether moderating variables such as political knowledge or opinion have an impact on the magnitude or direction of the bias effects.
Religious Balance in the Middle East: A Study on how Geography Influences Christian Tolerance in the Jordan State
Conor Fishback, Brigham Young University Social and Behavioral Sciences The Hashemite Kingdom of Jordan in recent years has seen the majority of its neighbors fall into some kind of violent conflict. Throughout the Arab Spring and the years following, the Jordan state has been one of stability and peace. One possible reason for the stability of the country could be its level of religious tolerance. One way to look at religious tolerance is to look at the geographic landscape of where the religious buildings are located within the cities of that country. This study analyzed the specific location of Christian churches in relation to Muslim Mosques in five different cities with a significant Christian population. Specific points representing the different faiths were gathered using GPS and then analyzed using GIS software. The geographic situation was analyzed for each structure. Geographic situation in this case referred to Christian churches and their proximity to Muslim Mosques, as well as the number of Muslim mosques and how adjacent they are in relation to the Christian churches. Photographs were taken of every location to determine the level of overshadowing or dominance that was taking place in that specific site. Using GIS, the Christian quarters in each city was analyzed. The majority of the cities, including the Jordanian capital of Amman, showed little or no clustering of mosques in relation to churches as well as little evidence of building dominance by either sect. Only one out of the five cities studied showed serious clustering of mosques around the Christian areas. While this study only analyzed a small part of what makes up a country’s level of religious tolerance, it can be expanded to other countries as well – not only Muslim states that are tolerant to Christianity, but also Christian or Western states and their tolerance to Islam.
Becoming an Adult on an Island
Peter Busche, Brigham Young University Social and Behavioral Sciences An undergraduate study on young people in the Channel Islands (near England and France. Such questions will be addressed, such as: What makes growing up in a tiny Island community unique? How does leaving the Island for the outside world affect the young peoples’ transition into adulthood? This project consists of a descriptive outline based on 2 months of ethnographic research, as part of a 10,000 word senior thesis. Current anthropological and psychological theories are part of the overall construction of the data.
EMS Personnel and the Effects of Divorce
Chelsey Kenney, Utah Valley University Social and Behavioral Sciences The purpose of this study was to compare the stressors and supportive resources found between Utah emergency medical service personnel who divorced after certification to those who did not divorce.
Authors
Joshua Smith, Utah Valley University Social and Behavioral Sciences The current veteran populations that comprise Level 1 (18-24 years old) and Level 2 (25-34 years old) have had higher unemployment rates than their counterparts in the civilian population. One reason for this discrepancy is that veterans have put their lives on hold to make a commitment of public service by serving in the military. When they return home, many struggle to adjust from life in the military to civilian life. One issue includes finding employment in their areas of expertise without having a degree from a higher education institution. Many employers that are seeking veterans for their military experience prefer them to have a college degree in addition to their specialized training. Veterans are encouraged once they leave service to find a college major that best matches the skills and experience they gain while serving in the military. However, many veterans do not understand the full education benefits they receive from the government, what college majors best match their skillset, and what kind of benefits they can get from earning a college degree. Veterans have a lot to offer to both the college environment and workforce with their advanced technical and personal skills. This research paper will help determine if veterans do understand their educational benefits, if they have or will use their educational benefits, if they know what degrees could apply to their military training, and what the Veterans Administration and higher education institutions can do to better serve veterans to succeed for a life after the military with a college degree.
Land Use Implications on Rural Community Resilience, National Security, and Climate Change in Brazil
Maximilian Stiefel, University of Utah Social and Behavioral Sciences This paper examines the impacts of sugarcane cultivation on rural community resilience in municipios throughout Brazil. Whether sugarcane cultivation has generated vulnerabilities, such as population diffusion, ecological transformation, and adverse path dependencies, for rural community resilience is the primary focus. Resilience is critical in that it demonstrates adaptation efficacy for a community facing shifting capabilities. Social cohesion and capital also tie into how resilience correlates to meaningful interactions among individuals. Over the past thirty years Brazil became second to the U.S. in terms of global ethanol production, generating robust economic growth. However, sugarcane cultivation expansion has forced some cattle ranchers from southern Brazil to migrate north, resulting in the clearing of Amazon forestland for grazing. Pastureland displacement from sugarcane cultivation generates various concerns for rural economies, social cohesion, and socioeconomic class disparities. There currently lacks abundant examination of impacts to rural communities adjacent to sugarcane ethanol cultivation and production. I formulate a regression analysis to gauge shifts in resilience from sugarcane cultivation that will include a variety of metrics such as employment rates, livelihood diversification, and educational attainment. From this information I will suggest practices that afford a more resilient economic, agricultural, and social model for rural communities. The suggestions I put forth will not be palliative, but will instead be consistent with sustainable practices that foster capabilities, socioeconomic equality, and environmental stewardship. Resilient rural community development models avoid historic deforestation patterns and aid climate change mitigation, which in turn safeguards Brazil’s myriad economic sectors. Robust rural economies support national security by ensuring a healthy agricultural sector, avoiding unsustainable urban migration, and reducing poverty. The models and practices I suggest will inform policies and programs for Brazilian officials, agriculturalists, and conservationists to support rural communities, mitigate the impacts of climate change, and increase national security.
Personality, Genetic, and Biological Factors Linked With Social Dominance in Rhesus Macaques
Mason Bennett, Brigham Young University Social and Behavioral Sciences In the natural environment, rhesus macaques (Macaca mulatta) acquire social dominance rank through matrilineal family (mothers’) inheritance. It is unknown as to how high ranking matrilines initially become high in social dominance. Serotonin (5HT) has been linked to social dominance rank. Central Nervous System 5HT is modulated by both the serotonin transporter (5HTT) and MAO and both have been linked to social dominance rank. MAOa and the 5HTT are the two main variables controlling central serotonin. To assess the effects of genetic and temperamental variables on matrilineal rank and potentially the effects of rank on behavior and temperament, we examined: the serotonin transporter genotype and MAOa genotypes. Because low or unstable social dominance rank is stressful, leading to chronic hypercortisolemia we also measured stress-induced cortisol levels. Lastly we examined infant temperament ratings taken from a Bio-Behavioral Assessment (BBA) pioneered by John Capitanio. This test is performed over a 24 hour period when infants are 6 months of age, and includes a bio-behavioral battery of tests designed to measure temperament. Dominance was measured by wins/losses during head-to-head competition between all possible pairs in a group. Subjects included 2300 rhesus macaques raised at the California National Primate Research Center between the years of 2001-2012. Results showed that matrilines high in social dominance exhibited a significantly high rate of both the long allele of the serotonin transporter genotype, and for males a high frequency of MAOa allele 6. As infants, subjects from matrilines low in social dominance rank exhibited high cortisol, hypervigilance, low activity ratings, and high emotionality. This study is the first of its kind to suggest that the acquisition of dominance by a matriline is modulated by genetic influences and that it is likely that the serotonin system plays a role in this process.
Nationality Bias: Evidence from International Soccer Referees
Bryson Pope, Brigham Young University Social and Behavioral Sciences Purpose of the Project:
Measuring nonconformity to familial values
Chantelle Fitting, Brigham Young University Social and Behavioral Sciences Rebelliousness is often the product of an effort to express individualism and is an outlet for uniqueness (Imhoff & Erb, 2009); however, it can have very detrimental consequences. When a person strives to not conform to his or her family’s beliefs and values, familial relationships become strained, and the potential arises for the family to be torn apart. This nonconformity manifests itself through the beliefs a person has and the actions they take that are markedly different from those chosen by family members. The Nonconformist Assessment Scale (NCAS) is a ten question survey that is used to measure an individual’s inclination to rebel against his or her family unit. With the NCAS, we seek to discover indications of early rebelliousness, which are manifested through a person’s deviation from the family in areas such as weekly activities and personal interests. By detecting the seeds of nonconformity that arise in early life within the family, family therapists can intervene before more severe rebelliousness such as illegal activity, abandonment of core family values, or other dangerous behaviors emerge. Cronbach’s Alpha of the NCAS was found to be .7195, giving the test acceptable reliability. The Pearson bivariate correlation indicated that every item except item nine correlated positively with at least seven other items. The items loaded onto a single factor, and the variance explained by this factor was .7019. Thus the NCAS is a good indicator of nonconformity to familial values. However, the domains of actions and beliefs were not discernible as the items loaded only onto a single factor, so further research could be conducted that includes items where these domains are more easily separated from each other.
The Role of Empathy in Attachment
Michelle Hammon, Dixie State University Social and Behavioral Sciences A caregiver’s ability to meet their infant’s physical and emotional needs is important to development. Infants who are unable to get their needs met are at risk of developing an insecure attachment with their caregiver. The ability of the caregiver to empathize with and appropriately respond to the needs of their infant is dependent on the caregiver’s attachment representation. An online survey collected data from 112 college students. Participants completed the Experiences in Close Relationships-Revised (ECR-R) scale and the Interpersonal Reactivity Index (IRI). Insecure attachment representations were associated with the ability to empathize. Anxious-ambivalent attachment was positively associated with concern and distress and avoidant attachment were negatively associated with distress. These results suggest that attachment representations are important for the development of empathy.
Panem and the United States: A tale of two countries and their use of mechanisms of control in maintaining inequality between classes
Katherine Abarca, Westminster College Social and Behavioral Sciences The Hunger Games series has sold 50 million copies of the three books as of July 2012, has an impressive fandom, and has significant influence on popular culture. One of the many reasons for the success of the series is that its shocking story is set in a society eerily similar to the United States. The fictional country of Panem and its similarities to the United has caused it to gain interest in academia. Utilizing textual analysis, I examine how the fictional country of Panem is similar to present day United States in its inequality between classes and use of mechanisms of control. I also discuss how this cultural artifact affects our understanding of our society and how our society is reflected in the books. This research will expand the limited academic literature analyzing the Hunger Games. In addition, this research will focus on the different mechanisms of control in how they maintain inequalities between classes rather than stopping at analyzing the mechanisms themselves.
CRH Promoter Mutation Inhibits HPA Axis Negative Feedback
Patrick O’Connell, Brigham Young University Social and Behavioral Sciences Studies show that the CRH gene has several variants that are associated with psychopathological disorders and dysregulation of the HPA system, including a single nucleotide polymorphism (SNP) located on the promotor region (201 C/T). In rhesus macaques there is a orthologous SNP in the promoter region of the corticotrophin releasing hormone gene, CRH-248 C/T, that up-regulates the production of corticotrophin releasing hormone (CRH), inhibits the down-regulation of CRH expression in the presence of glucocorticoids, and is related to stress-induced alcohol consumption (Barr 2009). HPA Axis differences due to genotype will manifest initially in CRH concentrations, affecting the hypothalamic pituitary adrenal stress response (HPA axis). This effect translates peripherally in the form of plasma ACTH concentrations and subsequently in concentrations of plasma cortisol. 180 rhesus monkey subjects reared either with their mothers or in adult-absent, peer-only groups were genotyped and underwent a series of social separations from their attachment source. Blood samples were obtained one and two hours following separation to assay for ACTH and cortisol. Our analyses showed a significant effect of the orthologous CRH-248 genotype on plasma ACTH concentrations following repeated experimentally induced stress. Further analyses showed that this genotypic difference was only found however in the peer-reared subjects. Interestingly, analyses showed no effect of genotype on plasma cortisol levels. This finding suggests while negative feedback at the level of CRH is disrupted leading to pituitary hypersecretion of ACTH, intact negative feedback at the level of the adrenal cortex may moderate this dysfunction. Additionally, genotypic effects were only different after prolonged, chronic stress, as measured separations three and four. We suggest a GxE effect with CRH genotype effects only present after deleterious rearing experiences and chronic or repeated stressful situations.
Resiliency and Red Flags of PTSD and Suicide Among Utah EMS Personnel
Kent Hinkson, Utah Valley University Social and Behavioral Sciences PTSD has become increasingly more concerning to the mental health world over the past few decades. A plethora of events (both acute and chronic) that serve as a triggering moment in the lives of those afflicted by this potentially debilitating condition are beginning to be identified more consistently. Yet, it continues to remain an area of concern because of the manner in which it affects nearly every aspect of its victim’s life.
Sustainability Officers: Centralized Leadership in Sustainability within Higher Education Institutions and Municipalities
William Ng, Utah Valley University Social and Behavioral Sciences This paper draws on leadership and behavioral theory in a public context to ascertain the full necessity of the sustainability officer to engender, sustain, and develop sustainability movements in higher education institutions and municipalities. As sustainability rises in awareness and demand from university and municipal stakeholders — influenced by political and educational discourse, the sustainability officer plays a vital role in conceptualizing, interpreting, and manifesting the abstract principles that stems from sustainability movements. Specifically, this study looks at the emergence of the sustainability officer, who they are, where they come from, what they do, and the outlook of future trends. Moreover, this paper looks at the structural positions of where sustainability officers fit in the organizational hierarchy and question whether they fall in line with contemporary political theory of public organizations. Furthermore, through interviews with Sustainability Managers/Coordinators/Directors, an intimate look into where they have been effective, where they could progress, and what they envision for themselves in the future has been garnished. Finally, these interviews manifest the establishment of the pragmatic connection between organizational theory and practice, allowing an exposition of the evolution of centralized sustainability leadership.
Political Knowledge and Extra-Governmental Activism in Peru
Lucas Brook, Brigham Young University Social and Behavioral Sciences Present day Peru finds itself in the midst of an interesting transition. Government decentralization is creating increased levels of political participation among the historically skeptical citizenry (Crabtree 2011). While some Peruvians participate through established institutional channels such as voting, campaigning or contacting political leaders, many others choose to engage in community improvement activities, private organization undertakings, or public protests as their avenue of political participation (Booth and Seligson 2009). What causes some Peruvians to participate in these extra-governmental activities while others use established government institutions? Although the causes of political participation are vast, this study focuses on political knowledge (both actual and perceived) as the independent variable. I hypothesize that Peruvians with less political knowledge (actual or perceived) understand (or at least perceive that they understand) less about Peru’s democratic institutions. Therefore, they will forgo participation through these established government institutions and employ extra-governmental means when participating politically. This hypothesis will be tested through the performing of regression analysis using data from Vanderbilt University’s AmericasBarometer survey project conducted in Peru in 2012. The results of this research will illustrate the effects that citizen’s political knowledge have on their participation in extra-governmental activism.
Quichua Unificado: Dialectical Demise through Language Standardization
Rebecca Holland, Brigham Young University Social and Behavioral Sciences Dialectical Quichua throughout Ecuador faces disappearance through the development of Quichua Unificado, a standardized form of Quichua used the bilingual school system. This form of Quichua was created in hopes that introducing a standardized orthography would help bilingual schools effectively address the Quichua language loss that is pervasive throughout the country. However, as the language steps beyond its intended bounds of being a written language and moves toward replacing dialectical Quichua as a spoken language, it is evident that this revitalization movement is progressing at a great cost. Original ethnographic research in the Napo Valley of Ecuador asserts that this movement is ineffectual at reversing the Quichua language loss in this area, and may in fact prove fatal to the future of spoken dialectical Quichua.
3D Mapping of Cardiac Nerves for Improved Cardiac Ablation Procedures in the Treatment of Cardiac Arrhythmia
Adam Jorgensen, Brigham Young University Life Sciences Arrhythmia is a serious heart defect that effects 14 million people in the United States. It is characterized by irregular rhythm in the electrical impulses of the heart. Arrhythmia can cause sudden cardiac arrest and stroke. Recent developments in cardiac ablation have helped in the treatment of arrhythmia. Cardiac ablation works by scarring tissue in the heart, thus preventing abnormal electrical signals to travel through the myocardium. The three-dimensional map created in this project will improve the accuracy of cardiac ablation by offering a more dynamic view of the human heart and associated nerve branches. By properly articulating the intricate nerve branching of the heart, surgeons will be able to better target the nerves themselves when scarring heart tissue, thus allowing a less invasive procedure.
Genomic analysis of six Paenibacillus larvae bacteriophages
Bryan D Merrill, Brigham Young University Life Sciences The spore-forming bacteria Paenibacillus larvae causes American Foulbrood (AFB), a highly contagious disease that is lethal in honey bee larvae. P. larvae is the most serious pathogen affecting honey bees. Its increasing antibiotic resistance has led to more research in characterizing bacteriophages which infect and destroy P. larvae. Of the 13 P. larvae phages that have been described in publications, six have been fully sequenced and are currently available for genomic analysis. To understand how P. larvae phages are related to each other and to other phages, the computer program Phamerator was used to analyze more than 100 phage genomes and group phage genes into “phams” based on similarity. Through analysis of grouped phage genes (structural proteins, terminases, recombinases, etc.) we can better understand in vivo replication strategies and evolutionary history of these P. larvae phages.
The Role of Endocannabinoid Receptor GPR55 on Learning and Memory
Bradley Prince, Brigham Young University Life Sciences Learning and memory occur due to adaptive brain changes in response to our environment. These changes are mediated by synaptic plasticity, particularly within the hippocampus, where spatial and declarative memories occur. Plasticity can either strengthen or weaken synapses, known as long-term potentiation (LTP) or long-term depression respectively. While many forms of synaptic plasticity are N-methyl-D-Aspartate receptor-dependent, recently endocannabinoids were identified to mediate several new forms of hippocampal synaptic plasticity. Endocannabinoids bind to receptors such as cannabinoid receptor 1 (CB1) and transient receptor potential vanilloid 1 (TRPV1), and mediate several forms of plasticity, including in the hippocampus. However, new research has demonstrated a non-CB1/TRPV1-dependent endocannabinoid synaptic plasticity in the hippocampus. While the receptor(s) involved is currently unknown, several potential candidate receptors that bind the endocannabinoid anandamide have been identified. These are orphan G-protein coupled receptors (GPRs) whose distribution in the brain and/or function is unknown. GPR55 is of particular interest as it activates second message systems, including increasing intracellular calcium. Using quantitative RT-PCR, electrophysiological and memory behavioral tasks we examined hippocampal GPR55 expression and function. GPR55 is indeed expressed in hippocampus of both rats and mice. Cellular expression is currently being examined and appears to be rare in interneurons and more likely expressed by pyramidal cells. Interestingly, application of the GPR55 agonist LPI (2 µM) to wild-type mice demonstrates a decrease of LTD in brain slices. This LPI effect was not noted in GPR55 knock-out mice in the presence of LPI. This data suggest GPR55 is physiologically relevant in the hippocampus. This is the first direct evidence we are aware of that a novel endocannabinoid receptor directly effects hippocampal LTD. Because neurodegeneration that affects memory is typically associated with an increase in LTD, this provides a potential target to slow the advance of diseases such as Alzheimer’s.
The effect of anxiolytic mediation administration on interval timing distracters
Chance Christensen, Utah State University Life Sciences Affective disorders such as depression, phobias, schizophrenia, and post-traumatic stress disorder impair the ability to time in the seconds-to-minutes range, i.e., interval timing. According to the Relative Time-Sharing (RTS) model, presentation of task-irrelevant distracters during a timing task results in a delay in responding suggesting a failure to maintain subjective time in working memory, possibly due to attentional and working memory resources being diverted away from timing. Given that some anxiolytic medications have beneficial effects on attention and working memory, e.g., decreasing emotional response to negative events, we hypothesized that they would result in a decreased effect of distracters on the timekeeping abilities. We investigated the effect of acute administration of anxiolytic medication when anxiety-inducing task-irrelevant distracters were presented during an interval timing task, using methods similar to Matthews et. al. (2012) Frontiers in Integrative Neuroscience 6(111): 1-12. Results are discussed in relation to the brain circuits involved in RTS of resources, and the pharmacological management of affective disorders.
Frog Behavior May Protect Against Potentially Lethal Chytriodiomycosis
Hailey Shepherd, Dixie State University Life Sciences Previous studies of canyon tree frogs (Hyla arenicolor) in Zion National Park have shown that some populations test positive for a dangerous fungus in the Chytridiomycosis family. This fungus has been linked to large population losses worldwide in many keystone amphibian species, but appears to have no effect on populations of H. arenicolor. Since Chytrid fungal growth is inhibited at high temperatures, we hypothesized the frogs are able to rid themselves of the fungus because they bask in the sun. During the summer of 2013 we swabbed frogs in multiple slot canyons to test for the presence of the fungus. We also recorded skin temperatures of the frogs we swabbed. Skin temperatures were as high as 38 C°, which is above the previously established lethal threshold of 28 C° for Chytridiomycosis. Our data support the idea that these frogs may be able to rid themselves of infection by allowing skin temperatures to raise enough to become intolerable for this fungus. This is the first known evidence of wild amphibian populations showing a behavior that may clear the infection. If further research supports these findings, it could lead to more effective allocation of limited conservation resources.
Genetic Origins of Mercury Resistance in Great Salt Lake Halophiles
Ashtyn Smith, Westminster College Life Sciences Methylmercury (CH3Hg) is a neurotoxin that accumulates in lakes and streams due to the action of microorganisms, which can produce this biologically relevant organic form from elemental mercury (Hg). Therefore, the activities of microorganisms become key to understanding the balance of Hg and CH3Hg in the movement through the food chain in any ecosystem. Many species of microorganisms are resistant to Hg and can thrive in polluted waters. Recent studies have shown that Hg resistance in microbes can stem from one of two gene pairs, merAB or hgcAB. The merAB system allows the organism to covert CH3Hg into elemental Hg. Conversely, the hgcAB system coverts Hg into CH3Hg. Thus, it is important to determine how the microbial community of Great Salt Lake, Utah is affecting the CH3Hg concentrations in the lake. In order to determine the genotype of the lake’s halophiles, “salt-loving” organisms, microorganisms were collected from the deep brine layer in eight areas of the lake. The microorganisms were then isolated and cultivated on increasing concentrations of HgCl2. Halophiles from these samples have been isolated on 25 ppm HgCl2 at various salinities, demonstrating a robust resistance to Hg. PCR amplification and genetic sequencing will be used to determine the gene mechanism of mercury resistance (merAB or hgcAB) as well as the 16S rRNA gene, which will aid in identification of the species. Should this study identify GSL microorganisms that exhibit the merAB genotype, these organisms could potentially be utilized as bioremediators of the CH3Hg pollution in the lake.
Utah Valley University/Huntsman Cancer Institute Collaborative Breast Cancer Study: High-Frequency Ultrasound for Margin Assessments
J Andrew Chappell, Utah Valley University Life Sciences In a joint effort with Huntsman Cancer Institute at the University of Utah, students from Utah Valley University are using high-frequency (HF) ultrasound to test the pathology of surgical margins from breast cancer conservation surgery. The method, developed by Dr. Timothy E. Doyle, provided significant results in a NIH-funded 2010 feasibility study. The results of the study indicated that peak density, the number of peaks and valleys in the HF ultrasonic spectrum, correlates to breast tissue pathology. This technology would allow surgeons to test – in the operating room – whether a surgical margin was clean or if cancer still remained in the margin. This advancement would decrease the amount of return surgical visits a patient must undergo, reduce costs for patients and hospitals, reduce breast cancer recurrence rates, and ultimately increase the survival rate of patients with breast cancer. During the ultrasonic testing, the students work in a team of four in a room outside of the surgical suite. Specimens are brought in by the surgeons’ team and tested immediately following resection. The margins are approximately 3x20x20 mm in size, and are oriented using a small staple inserted by the surgeon in one corner and a stitch on one side. The margin is tested at specific locations depending on the size of the margin and then sent to pathology for analyses. Pathological results and HF ultrasound results will be compared for correlation at the end of the study, which is expected to last about one year. The study will include approximately 80 patients, 360 tissue samples, 1400 tested locations, and 4,300 data points. The goal of the study is to evaluate the accuracy of the method in determining margin pathology. If successful, the method will be moved into clinical trial.
Standing on the shoulders of Woodrats: Adaptive Evolution in Desert Iguanas
Albert Pope, Utah Valley University Life Sciences Few animals are capable of using the creosote plant, Larrea tridentate, as food because of a high level of toxic secondary compounds. Some exceptions to this rule are Neotoma lepida and Dipsosaurus dorsalis which are both capable of sustaining themselves on this desert bush. In 2013, Magnanou et al helped identify heightened transcription of genes correlated with digestion of creosote in N. lepida. Building upon their findings, we explore whether the genes for digesting creosote are under an elevated evolutionary rate for D. dorsalis. We have obtained transcriptomes from whole blood of four Iguaninae species: Ctenosaura pectinata, D. dorsalis, Sauromalus ater, Cyclura lewisi yielding an average of 4 GB of DNA sequence data (~51,000,000 fragments) each. Using Velvet in Sequencher we assembled these data, recovering greater than 6000 unique RNA transcripts per transcriptome. We search through the contigs to identify genes in Iguaninae transcriptomes that are homologous to those showing differential expression in Lepida. Using BLAST, we retrieve homologous genes from the public NCBI database of Anolis carolinensis and other reptiles. Lastly we construct phylogenetic trees of each gene and investigate the rate of change along each reptile lineage.
Tissue Engineered Vascular Graft for Surgical Implantation
Dusting Day, Brigham Young University Life Science Atherosclerotic vascular disease is the leading cause of morbidity and death in the United States. Approximately 1.4 million surgical procedures are required every year for treatment of vascular disease and its subsequent issues. While saphenous vein and internal mammary artery grafts are most commonly chosen by physicians, many patients who are in need of arterial grafts have vessels that are not ideal for grafting because of damage to the vessels or disease. This introduces the necessity for synthetic blood vessel grafts that function precisely as natural vessels in vivo. Our blood vessel research team has entered the tissue engineering field in its most exciting effort: the scalable rendering of cell-seeded vascular constructs with rapid prototyping machines or 3D printers. We have built and are modifying a 3D printer to deposit living endothelial and smooth muscle cells into vascular structures. Using agar, alginate, or collagen gels as placement media, cells can be arranged in shapes resembling multilayered artery tubules and proliferate to form functional arteries. The endothelial layer and smooth muscle layer of cells interact to secrete a natural extracellular matrix (ECM) between them. We have successfully cultured endothelial cells and are perfecting our technique of harvesting aortic smooth muscle cells for culture. These cells will be encapsulated in a gel we have optimized for cell adhesion and proliferation and will then be printed with our rapid prototyping machine into the shape of a blood vessel. After proper cell growth and secretion of the ECM we will subject our synthetic graft to tensile strength testing, thrombosis tests, and eventually implantation into an animal for observation of any immunogenic effects. Our project’s success would bring an array of new treatment options through biomedical engineering that would save many lives of those who suffer from cardiovascular disease.
Predation Shapes Personalities in Brachyraphus Fishes
David Money, Brigham Young University Life Sciences Interest in animal personalities, and particularly the effect that different environments have on personality, has increased dramatically over the past decade. Understanding how individuals vary in their behavior, and if there are consistent differences among populations from divergent selective environments, lays the foundation for studies focusing on the contribution of divergent behavior in species formation. To date, studies that have focused on how personalities differ across ontogenetic stages have failed to compare populations that occur in dramatically different environments. Our study attempts to fill this void by studying the ontogeny of personality in populations that have evolved in environments with different levels of risk (i.e., predation vs. no-predation). We tested the expression of different personality traits evolution across ontogeny (i.e., from juveniles to full grown adults) in two sister species of live-bearing tropical fish, Brachyraphis roseni and B. terrabensis. These species have evolved in different selective environments, with B. roseni having evolved in an environment where predators were present, while B. terrabensis evolved in an environment lacking predators. We assessed the boldness expression of individuals from several groups in populations, namely juveniles, small adults, and large adults. To measure boldness, we used an emergence test, and also an exploration and activity test (i.e., ratio of movement to idleness during an allotted time period). Our study provides evidence for an important relationship between predation environment and the evolution of personality traits across ontogeny.
Prevention and Disruption of Bacterial Biofilms
Aimee Newsham, Dixie State University Life Sciences Millions of people are infected yearly with resistant pathogens, including MRSA (methicillin-resistant Staphylococcus aureus), a biofilm-forming pathogen that is often transferred to patients from contaminated surfaces. Therefore, improved methods to destroy biofilm-encapsulated pathogens or to prevent their initial formation are required. This research is focused on the development of a safe treatment against biofilms by integrating organic salts, or ionic liquids (ILs), into different surfaces. Textiles were integrated with ILs to prevent formation of biofilms/bacterial growth, and were also treated post-exposure to determine if the biofilms could be destroyed post-contamination. Effectiveness of newly designed ILs were tested via inhibition zone studies on LB agar plates, and post-treatment samples were analyzed via scanning electron microscopy for presence of bacteria. The bacteria tested included Pseudomonas aeruginosa, Staphylococcus epidermidis, and Escherichia coli. These microbes are similar to MRSA in that they form biofilms comprised of extracellular proteins, DNA and polysaccharides. Bacterial colonies encapsulate themselves with biofilms to provide protection from threats, including antibacterial drugs. By integrating ionic liquids into textiles, formation can be prevented by IL solvation and sequestering of the extracellular biofilm components, including the proteins and DNA. This research could have tremendous implications regarding defeating bacteria that are resistant to existing treatments due to biofilm encapsulation. Additionally, the results could lead to new antimicrobial textiles and new approaches to prevent adherence and growth resistant biofilm-encapsulated pathogens.
Intrauterine Growth Restriction Alters Estrogen Serum Levels and Signaling in Rat Adipose Tissue in a Sex Dependent Manner
Danielle Holliday, University of Utah Life Sciences Intrauterine growth restriction (IUGR) induces visceral obesity in adulthood, specifically among males. In male rat offspring, IUGR increases visceral adipose tissue (VAT) over subcutaneous adipose tissue (SAT). VAT and SAT functions are regulated by estrogen signaling, and suppressed estrogen signaling contributes to obesity development. Estrogen signaling is composed of estradiol and estrogen receptor alpha (ERα) and beta (ERβ). Estrogen receptors regulate the expression of several obesity related genes, such as lipoprotein lipase (LPL). However, the effects of IUGR on estrogen serum levels and signaling in the adipose tissue are unknown.
Extraction of Extracellular DNA from Environmental and Biological Media with Novel Surfactants
Derek Harris, Dixie State University Life Sciences The presence of extracellular DNA (eDNA) in various environmental and biological media has become the subject of growing interest in the field of research. In media such as bacterial biofilms, it has been shown to play a vital role in their structure and antimicrobial properties. Existing methods for extraction of pure eDNA from these media are complex and problematic; particularly from biological media where cells containing genomic DNA are also present. Novel surfactants have been developed, whose miscibility and polarity are easily tuned to suit a variety of conditions necessary for eDNA extractions. They can accomplish extraction of pure eDNA through concurrent hydrophilic and hydrophobic interactions in a single step, while remaining unreactive with the surrounding media or lysing cells and exposing genomic DNA. We have shown by spectrophotometric quantification that these surfactants extract measurable amounts of DNA into a water-immiscible solvent layer, which can then be removed from the media. The DNA can then be further amplified and purified for analysis. Further refinement of extraction methods utilizing these surfactants could prove a tremendous asset to research attempting to elucidate the possible genetic content of eDNA and the mechanisms behind its often crucial role in environmental and biological media.
3D printing from MRI data of stroke and Alzheimer’s disease subjects: An educational model of neurologic disease
Brett Gardiner, Brigham Young University Life Sciences Normal human anatomy used in the classroom is not reflective of variations confronted in pathology subjects. Current commercialized models are not products of real data, rather representations of it. While learning complicated medical anatomy, students take an enormous stride from the anatomy lab to situational surgical settings. 3D models can bridge this gap in medical education without patient risk, particularly for the brain where surface regions have strong associations to specific physiological activity. Subject specific models are especially advantageous for comprehending real surface morphology of neurologic diseases. Using rapid prototype technology, we have developed an accessible process to produce physical 3D models from specific MRI data of stroke and Alzheimer’s subjects. The neuroanatomical abnormalities modeled from real data by our 3D printouts will educate students on the anatomical variations encountered in an authentic clinical scenario of neuropathology. Our project consists of three phases: (1) image acquisition, (2) post-processing imaging data with segmentation, and (3) 3D printing. By delineating cortical regions we are providing a unique multidimensional facet of clinically accurate data not before available to the classroom. This powerful and versatile technique can allow students and professionals to visualize the inherently complicated structures as seen in clinical neuropathology. From students in the classroom, lawyers in the courtroom or preoperative surgical explanations, these customizable models will resemble real anatomical information. Through rapid prototyping of specific subject data, unique variations in pathology can be reviewed outside of the clinical setting. Beyond its potential use by teachers, lawyers and doctors can benefit from a 3D production to enhance their explanations of anatomical variations from specific pathological subject data.
Life at the Extremes: Finding Earthly analogs for potential life on Mars
Alysa Fratto, Westminster College Life Sciences Although the idea of life on other planets is mused over by many, the scientific study of the potential for extraterrestrial life did not begin until the mid-1950s (SETI, 2013). Since then, many technological advancements have been made that make the study of life on other planets simpler, however it is inherently difficult to study the potential for life in an environment that one cannot access. To address this issue, scientists look on Earth for extreme environments that mimic those found elsewhere in the universe.
Rapid adaptation of d2 dopamine receptor responses following acute ethanol
Joseph Linzey, Brigham Young University Life Sciences Dopamine (DA) D2 receptor expression parallels DA levels in the brain and these autoreceptors on DA neurons been shown to be modulated by long-term ethanol exposure. We have previously demonstrated that VTA GABA neurons also express D2 receptors, and that DA and D2 receptor agonists markedly enhance the excitability of VTA GABA neurons, opposite to their well-known inhibition of DA neurons. Most importantly, D2 receptor antagonists block ethanol inhibition of VTA GABA neurons and D2 receptor expression in VTA GABA neurons down-regulates with chronic ethanol. This study evaluates short-term D2 receptor adaptation in VTA GABA neurons and in DA release in the nucleus accumbens (NAc) by acute ethanol. In electrophysiology studies in anesthetized rats, periodic iontophoretic application of DA, or the D2 agonist quinpirole, markedly enhanced VTA GABA neuron firing rate, which was initially inhibited by ethanol, but resulted in latent and marked rebound excitation 30-60 min following injection. Using fast scan cyclic voltammetry (FSCV), we evoked DA signals in the core of the NAc by electrical stimulation of the medial forebrain bundle at the level of the lateral hypothalamus (60 Hz, 24 pulses). Intraperitoneal (IP) administration of ethanol (1.0-3.0 g/kg) dose-dependently decreased the amplitude of the MFB-evoked NAc DA signal. IP administration of the D2 antagonist eticlopride (1 mg/kg) markedly increased (250%) the amplitude of the evoked DA signal. When ethanol was administered after eticlopride it increased the amplitude of the DA signal an additional 42%. These findings suggest that ethanol induced decreases in evoked DA release may be due to autoreceptor feedback. Work is in progress to evaluate the short-term expression of D2 receptors in VTA GABA neurons following acute ethanol and to evaluate the effects of ethanol-induced short and long-term adaptations in VTA GABA neuron D2 expression in mediating ethanol effects on DA release in the NAc.
Biological effect of of oils spill dispersant corexit
April Moorer, Weber State University Life Sciences Corexit is a dispersant used in the gulf of Mexico as a reactive measure to counteract the oil spill of April of 2010. Studies reveal that toxicity is produced and has impacted marine life. Research shows that reproductivity is diminished as a consequence. Paralysis, tumor development, and fatalities are also proven to occur. The purpose of this experiment is to study effects on the physiological structure of brine shrimp at various life stages resulting from the exposure to toxicity induced by corexit.