Fine Arts

Authors: Bryce Tolman, Jasper Terungwa Iorkula , Justin Singleton, Matt Peterson. Mentors: Matt Peterson. Insitution: Brigham Young University. An efficient method for preparing C-3 aminated pyrazolo[1,5-a]pyrimidines was developed. The method consisted of treating 3-bromopyrazolo[1,5-a]pyrimidine with a wide range of 1° or 2° alkylamines with CuI (20 mol%), L-proline (40 mol%), and Et 3 N (2 equiv) in DMSO under microwave heating conditions (130 °C, 4 hours). C-3 aminated products were obtained in good to excellent isolated yields (54–90%; ave. yield = 77%), and represents the most broadly applicable, non-palladium-catalyzed amination of 3-bromopyrazolo[1,5-a]pyrimidine ever reported. The coupling worked well for unfunctionalized 1° alkylamines such as butylamine, benzylamine, isopropylamine or cyclohexylamine, and more densely functionalized 1° amines with CH 2 - or CH 2 CH 2 -linked heterocycles were also well tolerated (e.g. pyridine-, indole-, thiophene-, and furan-linked methyl- or ethylamine derivatives). 2° Alkylamines such as morpholine, pyrrolidine, and piperidine also reacted well under these conditions. Heating under conventional oil-bath conditions required a more extended reaction time (40 h), but also gave products in good yield (72-76%) for both 100-mg and gram-scale reactions. A pegylated azide (11-azido-3,6,9-trioxaundecan-1-amine) was also coupled in good yield (65% yield microwave), demonstrating compatibility of this methodology for potential click-type applications. Our method is simple and efficient, and avoids drawbacks associated with alternative methods, including long reaction times, limited substrate scope, and required use of air-sensitive/extremely expensive palladium catalysts and specialized synthetic ligands.

Authors: Ellie P. Evans, Mmadili Ilozumba, Sheetal Hardikar, Neli Ulrich, Jennifer Ose. Mentors: Mmadili Ilozumba. Insitution: Utah Valley University. Cachexia is a complex syndrome characterized by severe weight loss and muscle wasting. It is also a prevalent complication in various chronic diseases, including cancer and acquired immunodeficiency syndrome. Recent research has underscored the pivotal role of the gut microbiome in systemic well-being. Furthermore, it has been shown that cancer patients suffering from cachexia have unique bacteria composition in the gut compared to that of non-cachectic patients. In the absence of stool samples, there are a few metabolites in the circulatory system that can be directly linked to gut microbiota. Examples include bile acids, and short chain fatty acids as metabolites produced by specific Phylum. The presence of these gut microbiota derived metabolites (GMDM) in the circulation indicate a compromise in the integrity of tight junctions in the intestines. These results prompted an investigation of GMDM as an indicator of gut permeability. Our hypothesis is that an increased concentration of GMDM in the circulation is linked to gut permeability, leading to the development of cachexia in patients with colorectal cancer.  This literature review provides a comprehensive analysis of the relationship between gut permeability and cachexia, seeking to identify which GMDMs are the most accurate indicators of specific bacteria linked to gut permeability, and subsequently, are accurate projectors of cachexia.  Acetic acid, a short chain fatty acid (SCFA) is a GMDM detected in the plasma of patients with gut permeability. Acetic acid makes up about 60% of the SCFAs produced by a healthy gut flora and 90% of it is produced by the genus Bifidobacterium. Our literature review will cover how closely a measurement of acetic acid and other GMDMs measured in plasma can be linked to gut permeability and to Bifidobacterium levels in the gut. Similarly, Indole is a GMDM produced by Escherichia coli and other indole-producing bacteria. Indole isn’t produced naturally anywhere else in the body. When it is naturally absorbed into the liver through the portal vein, it’s mostly converted into indoxyl sulfate. The heightened presence indole in plasma in sulfate-free forms could indicate that indole is being absorbed through holes in the tight junctions of the intestines, rather than through the portal vein. This information would allow cohorts that have collected plasma samples in the past to measure gut permeability by proxy, even if they’re unable to investigate the gut microbiota and metabolites present from stool samples. These connections found could further help us to use-already collected samples to find accurate biomarkers for early cachexia development in cancer patients. If an oral presentation is unavailable, a poster presentation would be great.

Authors: Isabella Scalise. Mentors: Conan Kinsey. Insitution: University of Utah.

Authors: Allison Stevens, Gennie Parkman. Mentors: Gennie Parkman. Insitution: Weber State University. The principal genes that are responsible for the conversion of benign nevi, or pigmented lesions, to cancerous melanomas have been discovered and validated. However, we are still identifying the additional genetic alterations that are responsible for the migration and invasion of melanoma cells and ultimately metastasis of these melanomas as that is where treatment needs remain. (Davies, et al., 2002)One gene that has been identified to potentially play a role in the metastasis of melanoma is thymocyte selection associated high mobility group box, or TOX. Based on one study, the levels of TOX gene expression were found to be elevated in melanoma brain metastases versus extracranial metastases (Bierman et al., 2022). These findings have led us to hypothesize that TOX plays a role in the migration and invasion of melanoma into the brain. Preliminary work has been completed to clone our gene of interest, TOX, into an expression vector and transduce mammalian melanoma cells to evaluate their effects on melanoma cell rate growth and migration. These experiments will identify the effect of TOX on the initiation and progression of melanoma cells through in vitro melanoma cell culture and experimentation before potentially progressing to well-validated mouse models of melanoma.

Authors: Matthew Stecher, Terungwa Iorkula, Matt A. Peterson. Mentors: Matt A. Peterson. Insitution: Brigham Young University. Tropomyosin Receptor Kinase (TRK) inhibition has become an effective therapeutic approach for treatment of a variety of cancers including soft tissue sarcoma, pilocytic astrocytoma, non-small cell lung cancers, colorectal cancers, glioblastomas, pediatric gliomas, papillary thyroid cancers, and secretory breast carcinoma. Despite the successful use of first-generation TRK inhibitors Larotrectinib and Entrectinib which have shown significant therapeutic response in patients, acquired resistance to these drugs has emerged and is creating serious barriers to maintaining long-term therapeutic efficacy. A common mechanism for acquired resistance is associated with the emergence of mutations. Hence, mutation-induced drug resistance continues to be a major challenge for both first- and second-generation TRK inhibitors. Here, we present the design of novel macrocyclic 3,5-diaminated pyrazolo[1,5-a] pyrimidine ligands with high potential for combating drug-resistant disease.

Authors: . Mentors: Jared Nielsen. Insitution: Brigham Young University. Objective: This study examines the role of positive reframing as a strategy to mitigate suicidality and enhance positive emotions. Background: Emotional regulation difficulties have been identified in numerous psychiatric populations, potentially leading to stress, incarceration, and tragically, suicide. Amidst the rising rates of suicidality among at-risk populations, this study aims to investigate the pivotal behavioral factors influencing suicidal thoughts and actions in autistic and socially anxious populations. Methods: Our investigation employed a longitudinal ecological momentary assessment study to explore the impact of various emotional regulation skills on positive emotion, negative emotion, and suicidality. We recruited 95 participants, 72 of which met criteria for inclusion, to answer daily surveys administered through a smartphone app that tracked emotional regulation use, positive emotions, negative emotions, and suicidal tendencies over time. Results: Our results indicate that for the social anxiety group, enjoying the moment significantly affects positive emotions (E=2.14, p<.05), but this effect is not observed in the autism group. Furthermore, both groups demonstrated that accepting feelings (E=4.40, p<.001; E=2.63, p<.01) and acknowledging that feelings don’t last (E=1.69, p<.05; E=3.13, p<.001) significantly increased daily positive emotions. Conversely, hiding feelings significantly decreased daily positive emotions in the social anxiety group (E=-1.76, p<.05). Self-blame increased negative emotions in both groups by, on average, four points. Regarding the reduction of daily average suicide composite scores, accepting feelings emerged as a significant factor for both groups (E=-1.88, p<.01; E=-2.15, p<.001). On the other hand, using self-blame significantly increased average suicide composite scores for social anxiety, mirroring its effect on negative emotions (E=1.42, p<.01). Conclusion: Positively reframing one's emotions is associated with increased daily positive feelings and reduced daily suicidal tendencies. This research sheds light on the complex interplay between emotional regulation strategies and their impact on mental health and emotions in these at-risk populations.

Authors: Robert Macdonald. Mentors: Troy Munro. Insitution: Brigham Young University. Due to the recent developments in the precision of small scale 3-D printing, the use of complex multi-dimensional heating geometries is now very feasible in microfluidics. Small channels can be filled with liquid metal and can become a heat source by passing an electrical current through the liquid metal. There is a desire for the creation of isothermal areas within microfluidic chips for processes such as polymerase chain reaction and melt curve analysis of DNA to detect mutations. One difficulty of designing isothermal areas in microfluidics is the complexity of the geometries involved and the precision needed to be useful. These two problems were addressed by using a finite element software COMSOL to simulate the microfluidic chip to aid in design iteration. Quick evaluation of the performance of different heating geometries in COMSOL allows for faster evolution of our design. Using these principles, a novel microfluidic chip design was developed with a simulated isothermal volume of 5 microliters and a temperature variation of <0.1 degrees Celsius.

Authors: Tanner Frahm, Eugene Kwan, Ravi Ranjan. Mentors: Ravi Ranjan. Insitution: University of Utah. Introduction:Stereotactic body radiation therapy (SBRT) is a non-invasive treatment for ventricular tachycardia (VT) that acts as a promising alternative to the current gold-standard treatment, catheter ablation. Preliminary clinical successes indicate the promise of SBRT while subsequent animal studies suggest that the mechanism of SBRT is novel and unknown. We propose SBRT may alter Connexin-43 (Cx43) gap-junction distribution in cardiac myocyte walls, affecting electrical conduction and reducing VT episodes. A large animal model was used to evaluate Cx43 changes post-SBRT, aiming to elucidate its mechanism of action. Understanding this could expand SBRT's use in arrhythmia management and explore myocyte reprogramming.Methods:A large animal model (n=3) underwent cardiac SBRT on portions of their heart. Each animal provided control, untreated tissue, and treated tissues. Post-treatment, the hearts were excised, perfused, and preserved. Transmural sections were processed for histological and confocal microscopy analyses to assess scarring and Cx43 distribution. An algorithm for semi-automatic myocyte segmentation and Cx43 distribution analysis was developed and used. Two-sample student t-tests were conducted to compare Cx43 distribution between treated and control regions. All image and statistical analysis were performed in MATLAB.Results/Discussion:Preliminary results for the three preliminary animals indicate that treated regions of the myocardium had statistically significant differences in Cx43 distribution (p-values < 0.05). Treated values (mean  standard deviation) were 48%  25%, 62%  26%, and 64%  17% of the distribution of Cx43 on the longitudinal ends while the untreated were 42%  30%, 44%  25% and 26% 16%. The proportion of Cx43 distributed along the longitudinal axis (the short ends of the myocyte) increased in all three animals. The results build on the findings of previous animal studies which suggested that the scarring like ablation was not the mechanism, but that Cx43 or other cellular components could be changing in response to therapy. Conclusions:The findings support the hypothesis that Cx43 distribution changes in response to SBRT indicating that the radiation could be inducing remodeling at the cellular level. Evidence of non-invasive cardiac reprogramming provides basic science credence to the preliminary and ongoing clinical studies evaluating the treatment in patients. The findings further inform and motivate more animal studies and analysis of changes to other cellular components.

Authors: Ty Wilson. Mentors: Amita Kaundal. Insitution: Utah State University. Climate-induced environmental stresses and the increased use of fertilizers to meet the increasing demand for food significantly threaten food production and soil health. In natural environments, microbes are vital to the growth and development of plants. Their presence in the soil allows for enormous flexibility and nutritional availability for plants, particularly those living in harsh conditions. A plant’s microbiome, especially the underground, plays a significant role in its growth and development and mitigates environmental stresses. Idaho and Utah are particularly challenging environments due to extreme temperatures and arid soil. However, despite these difficult environmental factors, the native plants of Utah and Idaho can thrive. Here, we are exploring the rhizosphere microbiome of Shepherdia x utahensis ‘Torrey,’ a hybrid of two highly drought-tolerant buffaloberry species, S. argentea and S. rotundifolia native to the Intermountain West region of the US to isolate plant growth promoting bacteria. In this study, we isolated drought-resistant plant growth-promoting microbes from the rhizosphere of hybrid buffaloberry. Root samples of hybrid buffaloberry were collected from three locations in Utah: the USU campus, Greenville Farm USU, and the USU botanical garden, Kaysville. The rhizosphere was removed from these root samples and pooled together. The bacteria were isolated on five different bacterial growth media twice. The isolated microbes were then purified using the streak plate method. Forty-six unique isolates were selected based on morphological characteristics and tested for four plant growth-promoting traits. Fourteen bacteria could show the ability to fix nitrogen fix, 18 produced a siderophore, 17 could solubilize phosphate, and 11 produced catalases. IAA production, ACC deaminase, and protease activity assays are in progress. All isolates will be identified by 16S rRNA Sanger sequencing.

Authors: Alexander Everett, David Bean, Jeremy W Bakelar, Randy L Klabacka. Mentors: Randy L Klabacka. Insitution: Utah Tech University. β-barrel assembly machinery (BAM) is a protein complex vital to cell survival in gram-negative bacteria that functions to insert proteins into the cell’s outer membrane. BamA, a protein composed of a membrane-bound beta barrel and several POTRA domains that protrude into the cytosol, is the primary subunit within BAM. It is suggested that BamA is conserved due to its widespread presence across the bacterial tree of life. Here we quantify the conservancy of BamA in 142 species of gram-negative bacteria from across the bacterial tree of life, with a focus on 120 species belonging to the order Enterobacterales. In addition, we compared the conservancy of BamA with other proteins with high and moderate levels of conservation in Enterobacterales. Lastly, we discuss regions of BamA that are of high conservation in the context of their potential as antibiotic targets.

Authors: Kylie Hansen. Mentors: Janis Boettinger. Insitution: Utah State University. Cache Valley, Utah, has unique soils due to environmental events such as Pleistocene pluvial Lake Bonneville. This lake extended about 20,000 square miles in Northern Utah, and its depletion left numerous shorelines, the most relevant being the Bonneville and Provo shorelines. These various water levels influence the geological formations in Cache Valley and the different characteristics of soil formation. An important soil-forming factor used to characterize varying soils is the parent material. Parent material is the original sediments the soil formed on and can be various things such as sediments deposited by gravity, streams, lake sediments, or wind. These different materials depend on the location and alter the soil properties. A dominant soil parent material in the Lake Bonneville area is sediment deposited by this lake. This type of parent material is identifiable by coarser-sized sediments, such as cobbles, gravel, and sand. This pattern is evident on terraces in Cache Valley’s lower soil layers, but the near-surface layers have fewer rock fragments and more fine sand, silt, and clay. This distinct difference in particle size leads to the question of what is the parent material source in the surface horizons of soil formed in Lake Bonneville deposits in Cache Valley. There is not much literature on this question and little documentation compares the soil profiles for different Lake Bonneville terrace levels (Bonneville shoreline compared to Provo shoreline). We hypothesize that the different particle sizes of parent material in the surface of soils formed dominantly in Lake Bonneville deposits is eolian sediment transported and deposited by wind. To determine this, we will sample soils across Cache Valley and analyze the fine and very fine sand sediments in plane-polarized and cross-polarized light. This process will identify various minerals within each soil horizon, showing possible differences in the upper and lower horizons. The minerals present in each soil will indicate the parent materials, allowing us to understand what is causing the different textured horizons in these soils and where the sediment originated from.

Authors: Reagan McKee, Vicente Fernández Lara, Jeremy Bakelar, Randy Klabacka, Dustin Kolste. Mentors: Randy Klabacka. Insitution: Utah Tech University. The capability to survive freezing temperatures is of crucial importance to ectothermic organisms inhabiting cold climates. The mechanisms that have evolved to minimalize the cellular damage incurred by freezing are of interest due to their applications in agriculture and medicine. fr10 is a gene identified in the wood frog (Rana sylvatica)that has been shown to reduce the cellular damage sustained in freezing temperatures. To date, fr10 has not been identified in any taxa beyond R. sylvatica and as such, the evolution of this novel gene remains ambiguous. Furthermore, the exact mechanism by which fr10 reduces freezing related damage has yet to be determined. We use bioinformatics scripts to scan 38 frog genomes to identify orthologs in divergent frog lineages across varying elevational and latitudinal gradients and examine the evolution of this novel gene. Understanding the evolutionary and ecological context of this gene can elucidate its function and may inform commercial and medical applications.

Authors: Justin Hawkins, Charley Beck. Mentors: Alex Tye. Insitution: Utah Tech University. This study aims to address a critical gap in our understanding of the geological history and tectonic evolution of the Andes mountain range in Argentina. The Andes were formed due to a convergent boundary between the Nazca and South American plates. We are interested in the history of this boundary and how these mountains were formed. To better constrain the history of crustal deformation in NW Argentina, we collected samples from the Sierra de Chango Real, located south and along-strike of the Eastern Cordillera, and conducted new apatite (U-Th)/He dating on these samples. We combined new apatite (U-Th)/He data with the existing apatite fission-track data to gain a more comprehensive perspective on the geological evolution of the region.Apatite (U-Th)/He ages for new samples from the Sierra de Chango Real are between 6.3 and 17.6 Ma. These ages indicate Miocene exhumation of the Sierra de Chango Real due to tectonic deformation. Also, the distribution of these ages within the samples offers valuable information regarding variations in uplift rates and thermal events, which contribute to a better understanding of the geological processes that have shaped the Andes mountains. Published apatite fission track ages from the same locations have ages of 38 Ma to 30 Ma. Together, the thermochronometric ages suggest a history of tectonic exhumation from 38 Ma until ca. 6 Ma. In conclusion, our current study and analysis of samples taken from Sierra de Chango Real, Argentina, in conjunction with published apatite fission-track data, contributes to a more comprehensive understanding of the region's geological history.

Authors: Amy Richards, Caleb Shelton, Jordan Colmenero, Mason Warenski. Mentors: Diana Reese. Insitution: Utah Tech University. Hydrogen gas has potential to be an excellent form of clean energy; unfortunately, hydrogen gas is difficult to store safely in its elemental form. Consequently, this research project investigated cyclic aminoborane complexes in which hydrogen (H2) can be safely stored. Utilizing computational methods, molecular dynamics simulations of four cyclic aminoborane compounds were performed using Q-CHEM 6.0, with a t-HCTHh density functional and cc-pVDZ basis set. Results were visualized using Molden 6.7 and VMD 1.9.3 then plotted using Gnuplot 5.2.8. Molecules selected for the investigation involve two constitutional isomers for both the 3- and 4- membered ring cyclic aminoborane complexes. The four molecules studied were (CH2)2NHBH3, (CH2)2BHNH3, (CH2)3NHBH3, and (CH2)3BHNH3, (hereafter 3N-B, 3B-N, 4N-B, 4B-N). Motions inherent in these molecules exhibited surprising differences. Specifically, in the 3-membered rings, the terminal borane (3N-B) exhibited more motion than the terminal amine (3B-N); however in the 4-membered rings (4N-B and 4B-N) the opposite occurred. Differences in these and other motions were quantified and qualified with respect to each molecule to gather data relevant to hydrogen storage potential.

Authors: Alyssa Muller, Russ Ross. Mentors: Russ Ross. Insitution: Utah Tech University. University course timetabling assigns rooms and times to courses, considering instructor availability, curriculum conflicts, and quality of life considerations. Computing an optimal solution is computationally intractable. Researchers have refined approximation algorithms that yield far better results than the conventional pencil-and-paper approach used at many universities, including our own. Transitioning to an automated system can be disruptive and poses both real and perceived risks to an institution. The implicit knowledge that humans bring to the problem is hard to fully capture within formal rules that a computer can understand. Our research addresses the impedance mismatch between abstract solutions and the messy real world.In this project we build on prior research to fit the specific needs of our university. We will pilot our system with a set of departments in parallel with the traditional by hand process. We will analyze outcome quality through subjective assessment and quantitative comparison between human and machine generated timetables.

Authors: Ashley Staten. Mentors: Jennifer Meyer. Insitution: Utah Tech University. Pterostilbene, a natural product found in blueberries and nuts, has been shown to be multifunctional. In low doses, it has been shown to be a potent antioxidant, while in higher doses, it has been shown to reduce cell proliferation, induce autophagy, and increase apoptosis. Recent literature has indicated that derivatives of pterostilbene can improve the functionality of pterostilbene in both cancer cell viability (reduction) and antioxidant capacity (increase). Previously, our group has synthesized and characterized the antioxidant capacity of a select group of pterostilbene derivatives, which have been functionalized to contain an additional alcohol and amine group. Most recently, we have synthesized a derivative containing benzylamine as the amine. This amine was chosen as benzylamine and drugs functionalized with benzylamine groups have been shown to have antiapoptotic properties. Currently, we aim to further characterize this novel pterostilbene derivative as we believe it has the potential to be utilized as a therapeutic in various disease states such as cancer and type 2 diabetes.

Authors: Michael Orr. Mentors: Md Sazib Hasan, Alex Tye. Insitution: Utah Tech University. Every year Landslides claim lives and cause billions in property damage. Zion National Park in Southwestern Utah has been monitoring a precarious rock column contained within the parks borders since 2019. The results of this rockfall will be damage to the land and historical structures located in the fall area. The data are collected by two instruments called vibrating-wire crackmeters that are connected from the cliff face to the pillar—these are electronic and provide a continuous feed of distance measurements. The project will be focused on analyzing a 4-year record of displacement of a precarious rock pillar from the adjacent cliff face from which it will eventually separate and topple onto a slope below. We will also be analyzing the environmental factors causing the movement of the rock column. Results of this modeling will help us better understand the driving forces behind rockfalls, possibly helping to mitigate future damage.

Authors: Vicente Fernández Lara, Reagan McKee, Randy Klabacka, Angelina Romero. Mentors: Randy Klabacka. Insitution: Utah Tech University. Aspidoscelis (family: Teiidae) is a genus of lizards with many parthenogenic species found in North America. The parthenogenic species reproduce asexually, meaning all individuals in these species are female. The native range of Aspidoscelis neomexicanus (the New Mexico whiptail) is within the Rio Grande basin in New Mexico and Trans Pecos Texas. It has been reported outside its foreign range in northern Utah (Salt Lake area) as an introduced/invasive species, but has never been reported in southern Utah. We captured three individuals in Washington County that have the superficial diagnostic characters of Aspidoscelis neomexicanus. Using molecular genetics, we will test the taxonomic identity of this species and use phylogenetic analysis to determine the source population from its native range.

Authors: Taylor Millett, Wendy Schatzberg, Samuel Tobler. Mentors: Wendy Schatzberg. Insitution: Utah Tech University. This study delves into the intriguing world of hollow hair strands in animals, focusing on their role in thermoregulation, and the ability to maintain a stable body temperature in the face of fluctuating external conditions. While the Pronghorn antelope is widely known for having hollow hair strands among hunters and conservationists, little is known about their internal structure. Employing scanning electron microscopy (SEM), we explored the inner composition of these hollow hair strands and their contribution to thermoregulation. Our investigation centered on several notable North American big game animals, including Mule deer, Rocky Mountain elk, and Pronghorn antelope, all of which exhibit a unique adaptation: the transition between summer and winter coats. Through SEM analysis, we measured and compared the winter and summer coats of these animals to gain insights into how they effectively regulate their body temperatures during the extremes of hot summers and cold winters. These seasonal changes manifest in alterations in fur and hair thickness and length. Under the microscope, we unveiled the distinct topography of the inner structure of individual hair strands. Notably, our findings revealed that the inner hair structure contains larger hollow pockets in the winter coats of these animals. Our research thus sheds light on the role of these hollow structures in heat transfer and their pivotal contribution to the thermoregulation abilities of these remarkable creatures, expanding our understanding of their unique adaptations.

Authors: Grace Harang, Avery Hansgen. Mentors: Zhenyu Jin. Insitution: Utah Tech University. Title: Utah Tech Capus Temperature Mapping with GISAuthors: Grace Harang and Avery Hansgen, Advisor: Zhenyu JinAbstract: Across America, college campuses are re-evaluating their landscaping decisions to better support the environment. Utah Tech University, in the Mojave Desert, has a large amount of grass across the campus which is extremely water-consuming, non-native, and expensive to upkeep. However, removal of grass would result in lower humidity and even higher temperatures on campus. Our research will quantify how the temperature may be affected based on land-cover. This will be essential to any future decisions by the school board. Our method will be to map out 45 evenly spaced points across Utah Tech campus, 15 grass land-cover, 15 xero-scape cover, and 15 bare concrete (parking lots). At both 10am and 9pm. At each point, we will record the humidity and air temperature. To ensure that the sun rays and wind-chill are not also being read, we will use an umbrella to shade the measuring device. The purpose of this project is to determine the temperature difference between the three different surfaces, and to use GIS spatial interpolation to make campus temperature maps.

Authors: Austin Meyer, Gavin Grimmett, Martina Gaspari. Mentors: Martina Gaspari. Insitution: Utah Tech University. DNA can form non-canonical base pairings, resulting in structures distinct from the conventional double helix. One such example is the Hoogsteen base pairing, which can give rise to triple helix DNA. Triple helix DNA plays essential roles in regulating DNA metabolism and gene function, but its unusual nature is inherently mutagenic, sometimes leading to conditions like cancer. Recent research has uncovered that colorectal tumors exhibit significantly higher activity of triplex DNA binding proteins compared to their normal tissue. To explore this correlation, this study aims to employ cell and molecular biology techniques to investigate the relationship between the rise in triple helix DNA binding proteins and the presence of DNA triple helices. We initiated our study by extracting total RNA from HeLa cells, followed by the design and synthesis of specific primers for cloning ORC2 and ORC4 by RT-PCR. The experiment is further designed to analyze the potential consequences of ORC2 and ORC4 overexpression in human cell lines. Expression vectors containing ORC2 and ORC4 will be transfected into WI-38 cell lines comparing them to untransfected ones with hope of observing an increase of the proteins of interest and of triple helix DNA. The cell lines will be lysed, the total protein will be extracted, and Western blot will be conducted for comparison. Triple helix DNA will also be measured by calorimetric melting and high-speed centrifugation.

Authors: Erick Gutierrez, Sazib Hasan, Vinodh Chellamuthu, Jie Liu. Mentors: Sazib Hasan. Insitution: Utah Tech University. Breast Cancer is the second most common cancer among women in the United States.In 2023, the American Cancer Society anticipates the diagnosis of 297,790 new cases of invasive breast cancer, with approximately 43,700 women expected to lose their lives to this disease. It is crucial to undertake research endeavors aimed at discerning genetic sequence patterns to facilitate the classification and treatment of breast cancer. Recent work has shown that Machine Learning techniques are effective at classifying breast cancer using genetic sequences. Our research employs the METABRIC Breast Cancer Gene Expression Profiles dataset and machine learning techniques like Multi-Layer Perceptrons (MLP) and Random Forest to explore the link between survivability, treatment, and specific genes in breast cancer patients. Predicting survival based on gene sequences and treatments can inform effective countermeasures and research priorities.

Authors: Dante Celani, Erin Bunch, Randy Klabacka. Mentors: Randy Klabacka. Insitution: Utah Tech University. Hybrid parthenogenic whiptail species have lower endurance capacity and mitochondrial respiration than their sexual parental species. These differences in aerobic performance may be due to reduced compatibility of variable gene products between the divergent parental genomes that are present in the hybrids. If this is the case, we expect to see genetic variation in mitochondrial-targetting genes. We performed whole-genome sequencing for four sexual whiptail species that are parental species to hybrid parthenogenetic species, and we mapped those samples to an annotated whiptail genome. We call gene variants and classify them as coding, non-coding, synonymous, and non-synonymous to understand which variants might contribute to phenotypic variation, and we discuss approaches to further elucidate the genetic mechanism behind the lower aerobic performance in hybrid parthenogens.

Authors: Charley Beck, Justin Hawkins. Mentors: Alex Tye. Insitution: Utah Tech University. Thermochronometry dating of apatite (U-Th/He) of Andes Plate Tectonics from the Sierra de Altohuasi Charley Beck, Justin Hawkins, Alex TyeDuring the Cenozoic time period plate tectonics caused uplift in the Eastern Cordillera. We constrain the geologic evolution of the southernmost Eastern Cordillera through (U-Th/He) dating. Our results advance our understanding of the convergent plate boundary of the South American Plate and the Nazca Plate. The exhumation event caused the formation of the mountain range found in the Sierra de Altohuasi. Four samples were collected in the Sierra de Altohuasi near the town of Corral Quemado, Catamarca Province, Argentina. The samples were then analyzed using an apatite (U-Th)/He) system. The results indicated exhumation of the Sierra de Altohuasi from 28.6-13.3 Ma. This suggests an episode of exhumation during the Miocene and Oligocene, due to subduction of the Nazca Plate under the South American Plate. These apatite (U-Th/He) ages better constrain the exhumation history of the Eastern Cordillera. Further studies will show correlation of uplift events of the surrounding areas of Corral Quemado. Due to the compressed South American Plate, our data suggests the large mountain range formed under movement of the Nazca Plate.

Authors: Maggie Smith, Bryan L Koenig. Mentors: Bryan L Koenig. Insitution: Southern Utah University. Nationwide, Utah ranks 14th for suicide rates (CDC, 2021). To help prevent suicide, understanding suicidal ideation differences among certain populations such as sexual, ethnic, and racial minorities is important. One study found that LGBTQ+ individuals are three times more likely than non-LGBTQ+ individuals to attempt suicide at some point in their lives (di Giacomo et al. 2018). Religious background has also been connected to suicidality. Sterling and colleagues (2002) discovered that active LDS males aged 15–34 years have a lower risk of suicide compared with both less active LDS members and non-LDS individuals. Whereas some studies have samples of diverse ages and locations, research on suicidality among college students specifically in Utah is lacking. The purpose of the present research is to assess how demographic variables such as religious identity, biological sex, sexual orientation, gender identity, and racial/ethnic identity are connected to suicidality at a regional university in the Southwestern United States, Southern Utah University. In this study, 1,397 SUU Students took at least one of two surveys that asked about mental health variables and demographics. Suicidal ideation was measured using the Suicidality Suicide Behaviors Questionnaire Revised (Osman et al., 2001). Results indicate that the more minoritized identities students had, the more likely they were to be suicidal. Other findings include that LGBTQ+ students were very likely to be suicidal, cisgender students were less likely to be suicidal, and female students were more likely than male students to be suicidal. Additionally, suicidality was lowest among LDS students and highest among non-religious participants.

Authors: Breanne Herrmann. Mentors: Paul Stavast. Insitution: Brigham Young University. The construction and preservation of the Berlin Wall in 20th century Germany has perpetuated a social legacy perceived differently in various countries. Although the historical facts are unchangeable, their representation by institutions in each country varies and reveals their unique participation with the German Democratic Republic. This paper analyzes the portrayal of the Berlin Wall and surrounding GDR events in museums in both Berlin, Germany and American cities. Die Mauer, The Wall museum at Leipziger Platz in Berlin serves as a model of the German perspective. Its focus on the logistics of the Berlin Wall and the social impact in Germany and surrounding satellite countries is compared to the portrayal in American museums, which assume a more general approach of the Berlin Wall as a symbol of greater political struggles. This includes a consideration of locations of museums in America as well as information presented in the exhibits. Identifying differences between museums in these two countries provides insight into the experience of each during the GDR period and subsequent social perceptions of the Berlin Wall's history.

Authors: Maisie Baird, Hugh Kerry, Samuel Otterstrom. Mentors: Samuel Otterstrom. Insitution: Brigham Young University. Throughout the history of the United States, populations have experienced continual fluctuations across its diverse landscape. Although much research has focused on the growth and decline of cities and counties, many of these studies have focused on the positive population growth in larger cities and counties, insomuch that scholars and the public might have an incomplete or skewed view of the historical population geography of the country. However, this paper presents a broader perspective, including times of both population growth and decrease across regions and multiple decades and showing how these trends do not follow strictly positive trajectories nor exhibit isolated randomness. This paper will focus on specific examples of counties across the United States, highlighting why there were population ‘top-outs’ in these areas. For example, Sheridan County, Nebraska experienced a population boom at the onset of World War I, as it became the United States’ primary source of potash. However, at the end of World War I, potash could again be cheaply imported from Europe so, Sheridan County lost its booming industry, resulting in population decline. This research delves into the concept of population ‘topping out’ in counties, emphasizing a comprehensive understanding achieved through a holistic framework that accounts for geographic, regional, economic, and temporal aspects.

Authors: Kelsey Grimshaw, Julie Pynn, Kirsten Graham. Mentors: Kirsten Graham. Insitution: Southern Utah University. Epilepsy is the most common chronic neurological illness, yet very little is known about it. Studies have found that stigma has created challenges for people with epilepsy in economic and social capacities (Walker, 2018). It is suggested that stigma surrounding epilepsy is due to a lack of awareness (Al-Dossari, 2018). A Qualtrics survey will be administered to a sample of Southern Utah University students to solicit their awareness of epilepsy and their perceptions of stigma regarding people with epilepsy. Additionally, interviews will be conducted with a second sample of people who identify as having epilepsy to discover their perceptions regarding awareness and stigma. The results of the two samples will be compared. It is hypothesized that the stigmas identified in university students will be consistent with experiences described in interviews of people with epilepsy. The findings from this study could aid in the normalization and destigmatization of epilepsy and other chronic illnesses in society.

Authors: Annabelle Crawford. Mentors: Celeste Beesley. Insitution: Brigham Young University. Women who run for office do not fit societal leadership expectations, which hurts their chances of being elected (Bauer 2020; Eagly and Karau 2002). Women who serve in male-coded positions face backlash for confronting issues that are incongruent with stereotypically feminine attributes (Davidson-Schmich, Jalalzai, and Och 2023). I theorize that social role incongruence is exacerbated for women who serve on male-coded legislative committees. Therefore, I predict that women who serve on male-coded committees are reelected less frequently than women who do not serve on male-coded committees. However, I propose that women with leadership roles on male-coded committees are members of the political elite and therefore will be reelected at rates similar to other legislators. This research will employ a census of female legislators from both houses of the U.S. Congress who began their tenure between 1993 and 2022, using data compiled by the Congressional Research Service. Whether a committee is male-coded or female-coded (or gender-neutral) will be determined based on whether men or women dominate the industry associated with the committee. Social role incongruence will be measured by analyzing public perceptions of female legislators during the time they served on a male-coded committee. I will use regression analysis to determine the effect of serving on a male-coded committee on a woman’s gender role incongruence. I will then compare the proportion of reelection races won by women who served on a male-coded committee to the proportion of races won by women who served on a female-coded or gender-neutral committee using difference in proportions tests. I will also compare the electoral success of women who held leadership roles on male-coded committees to the electoral success of other legislators.

Authors: Kirsten Graham, Julie Pynn. Mentors: Kirsten Graham. Insitution: Southern Utah University. This study looks at how the LGBT+ population deals with concerns of identity, societal acceptance, and discrimination. The research identifies three primary coping mechanisms that affect resiliency: problem-focused coping, emotional coping, and avoidant coping. The purpose of the study is to determine how coping strategies and resilience relate to obstacles faced by Southern Utah University students. It makes use of qualitative data analysis, the Brief-Scale COPE, and the Brief-Resilience scales. I hypothesize with the quantitative data LGBT individuals who employ strong problem-focused skills are expected to demonstrate higher levels of resilience scoping, LGBT individuals who employ high levels of emotion focused-coping skills are expected to demonstrate low levels of resiliency, and those that demonstrate high levels of avoidant focused-coping are expected to demonstrate low levels of resiliency. Qualitative data analysis will reveal common thematic patterns in the use of problem-focused, emotion-focused, and avoidant coping skills among LGBT+ individuals, providing insights into their coping strategies related to discrimination, social acceptance, and identity. Understanding how the LGBT+ community at Southern Utah University manages to cope with challenges is crucial because it can result in better support and wellbeing. Results are forthcoming

Authors: Jared Hanks, Kevan LaFrance, Julie Pynn. Mentors: Kevan LaFrance. Insitution: Southern Utah University. Implicit Bias is a form of bias that occurs subconsciously but influences conscious actions. It often occurs as racial bias and in apolitical environments (Gassner, 2014). Research shows those who are more conservative leaning are prone to racial bias (Brown, 2019). This research will broaden our understanding of implicit biases with political preferences taken into account. Using an Implicit Association Test, participants will sort "good" and "bad" words as they sort African-American or European-American faces. Research shows there is a correlation between thought compatibility and speed as connections we subconsciously hold are made faster (West, 2021). We predict those with conservative views will have a higher rate of association between black and bad words than those with progressive views, and those who lean progressive will feel they have more implicit bias when asked. this research will enhance our understanding of political bias and more importantly those who take the test will be given a chance to assess their own biases and be provided some tools to live with bias or seek to combat it. Results are forthcoming.

Authors: Willow Norton, Kaleb Cox, Jaycen Sunderman, Jessalyn Warhurt. Mentors: Kirsten L. Graham. Insitution: Southern Utah University. Positive awe is a feeling of wonder, insignificance, reverence, etc., that is stimulated by man-made or natural events, objects, or circumstances. Monroy & Keltner list the five primary domains of awe as nature, spiritual engagement, music, dance, and psychedelics, but a scale determining the exact origin points of awe has not yet been developed. Upon researching awe more and determining that it is a universally felt emotion, we started looking at where awe may stem from, or what causes it. We have found that there are different types of awe, or that different populations may be able to feel it differently, but we could not find a measure of where it originates. In our study, we attempted to determine the sources from which people experience positive awe by developing the Positive Awe Origin Scale (PA-OS). While developing the PA-OS, we delivered our scale to five peers who tested the face value of our scale about readability and subject matter, and we then edited our scale based on the feedback we received. In the present study, participants will be recruited through social media and MTurk to complete an online survey, via Qualtrics. This survey will include likert scale items rated 1 to 5, with 1 being “strongly disagree” and 5 being “strongly agree.” Psychometric evaluation of results will include a confirmatory factor analysis and an internal consistency measure using Cronbach’s alpha. Discriminant validity will be measured as we correlate our scores with other, unrelated, scales included in the Qualtrics survey, which measure different constructs. Convergent validity will be measured as participants complete an awe subscale of the Dispositional Positive Emotion Scale (DPES). We anticipate that the PA-OS will help further identify the various sources of awe and lead to improvements in the research.

Authors: Alexa Smith. Mentors: Iliana Portaro. Insitution: Southern Utah University. Every day, more and more political ads are popping up in Spanglish or even full-out Spanish on screens across the United States. Whether or not these ads are effective is another story. The research conducted here was based on the hypothesis that in America, after its most recent, tumultuous presidential election cycle, given also that Spanish speakers are on the rise, a candidate’s bilingualism could mean the difference between winning a seat or walking home empty-handed. According to an anonymous online research survey conducted in Salem of Marion County, Oregon, this is only the case when a constituent places importance on a candidate’s language ability. Otherwise, the majority of respondents remained largely indifferent. Additionally, this study determines that more can be done to encourage Latinx individuals to participate in the political system, and it all starts with community outreach. The results of this survey are based on a small, mostly Caucasian sample size, but there is still much to be examined.

Authors: Alexis Downey, Kylee Navin, Brice Page, Alyssa Franklin, Hannah Cluff, Julie Johnson Pynn. Mentors: Julie Johnson Pynn. Insitution: Southern Utah University. “Gender expression refers to the way a person expresses their gender identity through appearance, behavior, and interests” (Helgenson, 2020). Previous research has shown that clothing has been used as a form of self-expression and that this expression of self-perception is more important for cisgender women (Strubel and Goswami, 2022). Additionally, previous research has found that conservative beliefs predict generalized prejudice toward gender-nonconforming individuals (Prusaczyk and Hodson, 2020). Felt pressure from peers and the self has been found to relate with greater gender typicality (Jackson et al. 2021), which leads us to believe that images of others may influence comfort and conformity with one’s own gender expression. The purpose of our study is to better understand the effects of appearance and political affiliation on comfort and conformity with gender expression. Participants were exposed to one of two visual manipulations: images of gender-conforming individuals, and images of gender-nonconforming individuals. Participants were asked to complete the Comfort and Conformity with Gender Expression Survey before and after being exposed to the images. We predicted that viewing images of gender non-conforming individuals would decrease participants' comfort and conformity with their gender expression, while viewing images of gender-conforming individuals would increase participants' comfort and conformity with their gender expression. Results will be forthcoming. Gender identity and expression are evolving rapidly, and it is important to examine masculinity and femininity in relation to gender non-conforming individuals rather than just gender-conforming individuals.

Authors: Reagan Wexels, Lauren Davis, Mason Peterson, Oliver Swanson, Rebekah Story, Julie Johnson Pynn, . . Mentors: Julie Johnson Pynn. Insitution: Southern Utah University. Environmental identity may affect an individual's pro-environmental behaviors, along with their association with the world around them (Clayton et al., 2021.) This concept demonstrates how people act according to their personality and values in relation to the natural world (Wesolek, 2020.)The degree of connection that an individual feels can be measured by the Connectedness to Nature Scale (Mayer et al., 2004.) The purpose of this study is to better understand the effect of Peter Kahn’s technological nature (2011) on people's connection to nature. We hypothesize that mindfulness meditation, which utilizes technological nature, will increase the connection to nature experienced by the participants in comparison to wilderness survival instruction utilizing technological nature. Research has established a link between mindfulness and an individual's connection to nature (Adventure-Heart et al., 2017.) Results will be forthcoming. The proposed study is important, because many people feel less connected to nature than ever. Understanding how to reconnect with the environment will allow greater access to the benefits of doing so.

Authors: Jacob Hutchings, Harrison Li. Mentors: Joe Price. Insitution: Brigham Young University. We examine the effectiveness of federal school nutrition policies and regulations; specifically, the recent transitional targets for sodium reduction announced in 2021. We performed web-scraping to gather over 5 million observations representing every U.S. state and over 2000 school districts and then constructed a weekly average of sodium served in school lunches by district. Using this data, we apply OLS regression with district fixed effects and find that the policy caused a significant, one-time reduction in weekly average sodium of approximately 220 mg. We further explore this result by looking at heterogeneous responses to the policy by political partisanship. We find that there is a significant, partisan response to the transitional targets. Lastly, we consider an adverse effect of sodium reduction by looking at potential sodium substitutes in school lunches. Contrary to expectations, our data shows a statistically significant correlation between decreased sodium levels and decreased sugar levels. To conclude, sodium reduction policies reduce sodium and other harmful nutrients but may be less effective across party lines.

Authors: James Hall. Mentors: Paul Stavast. Insitution: Brigham Young University. As of November 2023 the Utah Statewide Archaeological Society's social media pages have close to 4 thousand followers, which shows that interest in Archaeology. From 1955 to around the mid-90s USAS members contributed greatly to the archaeological research and the protection of archaeological sites and the materials created by those people that had called what is now Utah home. Through the partnership of Universities and Museums they had great success and this poster aims to highlight some of those successes and push for Museums to continue facilitating these opportunities.

Authors: Samantha Denbow, Katie Finlinson, Carley Grube, Joseph Johnson, Tanner Dougherty. Mentors: Kirsten L Graham. Insitution: Southern Utah University. Religious affiliation is rapidly declining (Engelman, 2019). Given that religions often perpetuate an in-group out-group dynamic, bidirectional prejudices can be seen between both people who are a part of and people who are not a part of religion (Jackson & Hunsberger, 1999). One explanation for this phenomena of leaving religion and increased prejudice is that there is a shift in attitudes towards religion. Attitudes affect behavior and may explain why people are leaving religion and becoming more prejudiced towards religious and non-religious groups. Our scale Attitudes Towards Religion (ATR) aims to measure attitudes towards religion to better understand why these cultural shifts are happening. We have defined attitudes as “a mostly enduring organization of thoughts, feelings, and behavioral tendencies directed towards objects, groups, events, or symbols” (Breckler, 1984; Hogg & Vaughan, 2005). Little research has been done to determine attitudes as a three part model (affect, cognition, and behavior) when examining religion. The current measures used to examine attitudes towards religion are less defined and fail to address the tripartite model of attitudes by relying more on affective and cognitive components of attitudes (Breckler, 1984). One such scale is called the Astley–Francis Scale of Attitude Towards Theistic Faith, which measures attitudes through affective items on a Likert scale. As demonstrated through this scale and others, many measures are also limited to attitudes of theistic, western religions, rather than encompassing nontheistic religions (Astley et al., 2012; Szydłowski et al., 2021). Attitudes are important to research because they impact daily choices in every individual’s life. Our study sample will be recruited through the Amazon Mechanical Turk survey platform and researchers’ social media pages. We predict our scale will measure attitudes towards religion to further inform current literature concerning religion and religious exit. We will examine reliability in our scale by testing Cronbach's alpha to ensure internal consistency. A small pilot group of 5 undergraduate peers reviewed the items for clarity, readability, and face validity. We then made changes to the items based on the feedback. Because our measure was developed according to a well-established tripart theory of attitude, a confirmatory factor analysis will be used to assess initial factor structure and how well our model fits the data. In addition, we will examine convergent validity by comparing the Astley–Francis Scale of Attitude Towards Theistic Faith with our scale. Discriminant validity will be examined by comparing other non-related scales that measure different constructs with our scale. With this information, further research can be done to understand the correlation between attitudes towards religion and religious participation/exit. The authors for this project are Samantha Denbow, Katie Finlinson, Joseph Johnson, Tanner Dougherty, and Carley Grube. This information will be presented in a poster format.

Authors: Michelle Stanley. Mentors: Baktybek Abdrisaev. Insitution: Utah Valley University. Due to the Russian invasion of Ukraine in 2022, much of Europe has been striving to reduce their dependence on Russian energy. Lithuania, however, began this process 11 years ago when Russia raised the price of Russian gas transported through Gazprom. Lithuanian leadership recognized the potential danger of being dependent on Russia and with the Russian invasion of Ukraine, those concerns proved to be well-founded. Through its history, Lithuania has experienced Russian oppression and has fought for its sovereignty. The history of Lithuania’s energy relationship with Russia from its declared independence from the Soviet Union in March 1990, its complete dependence on Russia for gas, and the process of becoming the first European Union country to become independent from Russian gas in May 2022. This is a case study which shows that: independence from Russian energy removes Russia’s coercive power over that country, the current European energy crisis is the culmination of long-standing European dependence on Russian energy, and that eventually European countries will have to reconcile with Russia. The article will outline three significant periods of time in Lithuania’s energy relationship with Russia: the Lithuania-Soviet Union energy relationship immediately before the fall of the Soviet Union, the process whereby Lithuania has pursued its energy independence from Russia since 1991, and Lithuania’s efforts to achieve full energy independence from Russia following the Russian invasion of Ukraine.

Authors: Cassandra Nelson, Braden Richards, Grace Van Buren, Fernando Gonzalez, Ian Kirkpatrick, Paul Dunn. Mentors: Paul Dunn. Insitution: Utah Valley University. Many organisms experience a life history pattern called ontogenescence, a high but declining mortality risk during early life. Ontogenescence can have a large effect on a population’s growth by limiting the number of new recruits to the population. Clearly, and yet paradoxically, death before reproductive maturity should be selected against, yet ontogenescence persists across many otherwise dissimilar organisms. Some intriguing hypotheses to explain this pattern have been proposed but have not been thoroughly tested. One of these hypotheses, acquisition of robustness as a function of age, is perhaps the most intuitive. The goal of our current research is to examine the validity of this hypothesis by using brine shrimp (Artemia franciscana) as a model organism.Tracking life-history traits like ontogenescence often requires the researcher to be able to follow an individual throughout its lifespan. In aquatic invertebrates, this means culturing animals individually, which can be quite difficult. Here we report on progress we are making with these culturing methods by testing how food availability and variety affect the early life mortality and development rate of brine shrimp in small-volume culture. Our null hypotheses are that neither of these variables will affect mortality or age to maturity in the animals. Our alternative hypotheses are that increased food availability and variety should lower mortality risk and age to maturity. To test our hypotheses, we hatched brine shrimp cysts in artificial seawater and placed individual artemia into wells of 6-well cell-culture plates filled with artificial seawater. We fed the shrimp one of several food treatments to see how diet affects development and mortality. In our first round of trials, we provided our animals with two different food concentrations (high food vs. low food) of the three food types we evaluated: a unicellular alga (Nannochloropsis), a cyanobacterium (Spirulina), and brewer’s yeast (Saccharomyces cerevisiae). In our second set of trials, we provided the shrimp with less variety in their diet (only two of the three food types). As the artemia developed, we conducted regular water changes and monitored development and mortality. We tracked the fate of the artemia until all individuals had either died during development or reached adulthood. Our food availability trials resulted in no significant difference in either mortality risk during development or age at maturity based on food concentrations. Trials examining the effects of limiting the variety of food types are ongoing.

Authors: Noah James, Rebekah Hakala, Todd Spencer. Mentors: Todd Spencer. Insitution: Utah Valley University. The Relationship Among Attachment Styles, Couple Satisfaction, and Perceived StressNoah James, Rebekah Hakala, Todd SpencerIntroductionAttachment styles play a pivotal role in romantic relationships. According to existing research, individuals with fearful, dismissive, or preoccupied attachment styles tend to experience elevated stress levels (Candel & Turliuc, 2021; Waring et al., 2019). Conversely, those with secure or preoccupied attachment styles report greater relationship satisfaction (Candel & Turliuc, 2021). By exploring the relationship between attachment styles, stress, and relationship satisfaction we hope to foster healthier relationships and deepen our understanding of the interaction between attachment orientations and emotional well-being (Candel & Turliuc, 2021; Waring et al., 2019).AnalysisThe purpose of the present study is to examine the relationship among attachment styles and couple satisfaction and stress. Our sample consists of 411 married individuals. Participants completed the Perceived Stress Scale - short form (PSS-4; Cohen, Kamarck, & Mermelstein, 1983), The Relationship Questionnaire (RQ; Bartholomew & Horowitz, 1991), and Couple Satisfaction Index (CSI-4; Funk & Rogge, 2000). Results of the one way Anova were significant F (3,407) = 10.48, p=<.001. There was a significant difference in levels of relationship satisfaction among attachment styles. Secure attachment (M=15.66, SD = 2.44), fearful attachment (M=14.09, SD = 3.30), preoccupied (M=15.75, SD = 2.35), and dismissing (M=14.05, SD = 3.54). Results of the Bonferroni Post-hoc analysis indicated a significantly higher levels of couple satisfaction than fearful and dismissing attachment styles (p.<.001). There was no significant difference in level of relationship satisfaction between Secure and preoccupied attachment styles. Additionally, there was a significant difference in levels of perceived stress among attachment styles. Secure attachment (M=11.79, SD = 2.47), fearful attachment (M=13.91, SD = 2.55), preoccupied (M=13.20, SD = 3.35), and dismissing (M=11.81, SD = 3.54). Results of the Bonferroni Post-hoc analysis indicated a significantly lower levels of stress among securely attached compared to fearful and pre-occupied attachment styles (p.<.001). There was no significant difference in level of stress between Secure and dismissing attachment styles. Results provide empirical support that secure attachment styles tend to be beficial for both relationship satisfaction and perceptions of stress. Further, dismissive attachment styles reported similar levels of stress as securely attached participants but had the lowest level of relationship satisfaction.

Authors: Alley Fausett, Megan Ritter Martin, Kristin Davenport, Malisa Brooks, Kent Hinkson. Mentors: Kent Hinkson, Malisa Brooks. Insitution: Utah Valley University. Background: University students oftentimes face challenges with well-being and mental health, including depression, anxiety, sleep problems, PTSD, and suicide ideation/behaviors. However, previous research in some areas such as depression and its impact on student’s academic performance has remained generally inconclusive because of the contradictory findings that have often been reported. For example, one study will find a moderate association between grade point average (GPA) and depression, while another will in turn fail to find a significant relationship. Thus, more research is needed beyond simple correlations between GPA and depression to understand possible mechanisms and pathways. The current research hypothesizes that depression symptoms will either not be related or be weakly related to GPA but will be significantly associated with several possible mediating variables such as “turning in assignments late”, “having withdrawn from a class”, and “being placed on academic probation.”Methods: University students (n = 1,359) were recruited to participate in this study from dozens of universities across the United States in 2021. Data was collected anonymously and confidentially through a targeted online survey. Students were compensated with a $10 Amazon gift card for their participation. Zero order correlations were conducted to examine the relationship between variables of interest, which may lead to possible mediating pathways.Results: No statistically significant correlation was observed between depression symptoms and academic performance among students. Yet, several other measures of academic performance beyond GPA were found to have negative relationships with depression including five questions of particular academic activity and items such as withdrawing from class, being placed on academic probation, etc. Further, the strength and significance of the relationship between depression symptoms and these measures of academic performance were stronger and more pronounced in those in their Freshman and Sophomore years. Additionally, the relationships were weaker during their Junior and Senior years, and practically non-existent in graduate programs.Conclusion: In summary, our study contributes to the growing number of often-contradictory studies demonstrating a sometimes-yes, sometimes-no relationship between depression and GPA. However, our study goes beyond this binary comparison to explore other variables of academic performance and found several significant relationships that can help the field better understand the impacts of depression on student’s performance. These findings emphasize the importance of addressing mental health for better academic outcomes for university students. Implementing targeted support systems and interventions within educational institutions could benefit students’ overall well-being and improve academic performance.

Authors: Audrey French, Carl E Hjelmen. Mentors: Carl E Hjelmen. Insitution: Utah Valley University. Chromosome numbers are often one of the first pieces of genetic information we collect about the genome of an organism. These chromosome numbers vary widely across the tree of life and will change due to fission and fusion events, where the number increases or decreases, respectively (Blackmon and Demuth 2015, Perkins et al. 2019, Sylvester et al. 2020, Morelli et al. 2022). As the Drosophila species group has been a model for more than 100 years, there is a plethora of information on their karyotypes, including number, chromosome shapes, and sex chromosome systems. The shapes of chromosomes vary and can be described as metacentric (v), submetacentric (j), telocentric (rod), and small and heterochromatic (dot). In the Drosophila genus, sex chromosome systems can be neo-sex, XY, and X0. The numerous species of Drosophila can be compiled into the major subgenera of Drosophila and Sophophora, which have diverged for around 40-65 million years. The karyotype data of the Drosophila genus has been compiled into an open-source database. I am using this database to find the rates of chromosome number change in the Drosophila genus. This analysis is done through the chromePlus package in R (Blackmon et al., 2019) which will perform a comparative phylogenetic analysis, and a phylogeny of 152 species in the Drosophila genus (Hjelmen et al., 2019). Using these available tools, I can compare rates of fusion and fission between sex chromosome systems and subgenera. This could expand the knowledge on evolution of chromosomes and genomes.

Authors: Nathan Klundt, Violeta Vasilevska. Mentors: Violeta Vasilevska. Insitution: Utah Valley University. In electrical power networks, phase measurement units (PMUs) are sensors used to monitor the network. However, these PMUs are very costly, hence the electric company are interested in using the minimum number of PMUs that will ensure that they can observe the whole network. This real-life problem is modeled in graph theory as a graph coloring game. Namely, the power domination problem [2, 3] in graph theory is concerned with finding a minimum number of these sensors needed to color (observe) the entire graph (network) according to a set of rules. We consider two variants of this coloring problem. The k-fault-tolerant power domination [3] is asking to find minimum number of PMUs needed to observe (color) the whole network (graph) even when k number of the PMUs are faulty but allows only one PMU to be placed on an electric node (vertex). The other variant, called robust power domination [1], asks the same as fault tolerant power domination, but allows for multiple PMUs to be placed on the same electric node (vertex). In this presentation, we introduce these coloring problems through examples, and provide some theoretical bounds on the minimum number of PMUs needed for various families of graphs for both k-fault-tolerant and robust power domination problems. References: [1] Beth Bjorkman and Esther Conrad. (2023). Introduction to Robust Power Domination. arXiv:2305.13430. [2] Dennise J. Brueni and Lenwood S. Heath. The PMU placement problem. SIAM Journal on Discrete Mathematics, 19(3): 744-761, 2005. [2] Teresa W. Haynes, Sandra M. Hedetniemi, Stephen T. Hedetniemi, and Michael A. Henning. Domination in graphs applied to electric power networks. SIAM Journal on Discrete Mathematics, 15(4): 519-529, 2002. [3] Kung-Jui Pai, Jou-Ming Chang, and Yue-Li Wang. Restricted power domination and fault-tolerant power domination on grids, Discrete Applied Mathematics, 158(10):1079–1089, 2010.

Authors: Mikaela Cowles, Joseph Jensen. Mentors: Joseph Jensen. Insitution: Utah Valley University. We are developing a newly calibrated distance ladder based on surface brightness fluctuations (SBF) to decrease systematic uncertainties in the current measurement of the Hubble Constant. James Webb Space Telescope (JWST) observations of 14 nearby elliptical galaxies are now being observed to measure a new zero point for SBF distances independent of Cepheids. We have recently acquired 69 images of massive early-type galaxies using the Hubble Space Telescope (HST). These HST distances have doubled the number of galaxy distances measured using SBF and will be combined with past SBF surveys to calculate the Hubble Constant to help resolve the Hubble tension. These distances will be added to the Cosmicflows-4 database to help map the mass distribution in the local universe. This project will continue with the allocation of an additional 123 HST orbits, from which we expect to add ~40 galaxies in 2024.

Authors: Asher Mitchell, Neil Chilson. Mentors: Neil Chilson. Insitution: Utah State University. With the rapid adoption of Artificial Intelligence marked by the release of OpenAI’s GPT model and a number of similar models, concerns are being raised about the potential for centralization of control over the technology, which could have implications like control of user data, increased political influence, lack of user choice, and several other potential issues.This paper focuses on an alternative to the currently proposed solutions to this threat; creating a separate regulatory agency for the technology, or legislating conformity to specific standards. We focus instead on different interoperability-based solutions that allow end users to tap into the source code, giving them the ability to ensure control of their data and allowing for competition in the AI market.

Authors: Kacey Rowe, Rachel Arocho, Allison Ensign. Mentors: Rachel Arocho, Allison Ensign. Insitution: Utah Valley University. Mental health amongst IBD patients is often overlooked and forgotten when they are dealing with their personal physical symptoms. There is little research on the benefits of social support for IBD patients. In online forums, it appears some IBD patients report feeling depressed and having negative thoughts about living life on a day-to-day basis. Indeed, prior research has found associations between IBD and mental health; for example, one study found that 17.3% of IBD patients had lifetime suicidal ideation, which is much higher than the general population at a 4.0% rate (Xiong et al., 2022). Another study did physical and mental exams and found on average, people with higher depression symptoms were six times more likely to have their disease be more active (Marrie et al., 2021, para. 16). Due to the high rate of depression, it would be beneficial to design a website to track symptoms and create online forums giving people the opportunity to connect with peers who have IBD. IBD can drastically affect a person’s life, even in a mild case. According to the CDC, IBD is estimated to affect 3 million US adults, a little over 1% of all Americans (Xu et al, 2018). Few people in the 1% category who struggle with IBD have connected online with others who are experiencing the same autoimmune disease. Although prior research has identified the association between physical IBD symptoms and mental health, little has been proposed to help these patients. Our goal is to create a form of social support for people who have been diagnosed with IBD. For 30 days, we will take 20 participants and have them record their symptoms and thoughts through quantitative and qualitative data. To do this, the participants will be asked to use a website which we have created from scratch. They will be using the Patient Health Questionnaire-9 (PHQ-9) and the Short Inflammatory Bowel Disease Questionnaire (SIBDQ). The PHQ-9 will be used to check in on mental health, while the SIBDQ will focus on the physical symptoms of IBD. Each week, they will participate in forums on the website, which will allow them to connect online and anonymously with others who share their experiences. At the start of the month, daily throughout the study, and at the end of the month, participants will report on their health symptoms through a combination of the measures named above and short tracker questions. (Note: Project is still under IRB approval, we aim to start participants by the end of the year.)

Authors: Aubrilin Johnson. Mentors: Yu Ya Liang. Insitution: Utah Valley University. Drought stress negatively affects the growth, survival, and production of crops. Developing drought-tolerant cultivars is an important strategy for maintaining crop yields under undesirable water conditions. Tomatoes are an important crop both grown worldwide and here in Utah. Improving drought tolerance in tomato plants can increase yearly yields and reduce the amount of crops lost during the periodic droughts that Utah has. A way to develop drought-tolerant tomatoes may be through identifying and utilizing genes that enhance survival and growth rates under stressful water conditions. In this study, we will use two varieties of tomato, including drought-tolerant wild species, and susceptible commercial varieties. According to previous studies, drought during late the vegetative stage will significantly reduce the yield, therefore this study will focus on that. Using RNA-seq to find the difference in gene expression between the control and drought groups. Identifying differences will facilitate in finding candidate genes that may have a potential role in drought resistance. Then take the top cultivar and find the specific drought-resistant gene, which can then be used by Utah tomato growers to yield more resistant crops.

Authors: Erica Webb, Joseph Price. Mentors: Joseph Price. Insitution: Brigham Young University. Blocking is a strategy used in machine learning to reduce the number of comparisons that need to be considered. In this paper, we develop a blocking strategy based on the characteristics of two people in the same household. We apply this pair blocking approach to link US census records and show that it dramatically reduces the number of possible matches to consider and can directly identify millions of unique matches at the blocking step. We apply our method to linking records for a few groups that have been harder to link using previous methods, including inter-racial couples and German-born Americans. Both of these are groups that have changed how they report aspects of their identity (race of birthplace) over time. Our approach allows us to dramatically increase the match rates for these couples across adjacent census years.

Authors: Grace McFarlane. Mentors: Michael Rotter. Insitution: Utah Valley University. Thimbleberry (Rubus parviflorus) is a native shrub to North America, and can be an important component in restoring native plant communities. Members of this genus tend to have physically hard seeds and low germination rates, resulting in a lack of ability to grow this plant by seeds and increasing genetic diversity in restoration sites. We investigated six different methods in order to produce higher germination rates, tracking them over time. Using seeds from three different populations we planted these thimbleberry seeds in groups of 50 for each germination method, monitoring the rates of growth and the success rate percent. These methods included standard planting as our control, cold stratification using a fridge, scarification with sandpaper, hot water bath by boiling the seeds, acid bath with sulfuric acid, and a room temperature soak in water overnight. Our goal is to identify a standard procedure for high germination rates and success.