2013 Abstracts

Kevin Boehme, Brigham Young University Biology Late Onset Alzheimer disease (LOAD) is caused by a complex combination of genetic and environmental factors. While multiple loci have been found associated with an increased risk of LOAD much of the heritability of the disease has yet to be accounted for. The prevailing thought now is that of rare variants playing an important role in LOAD. In this study we will use linkage analysis to identify novel regions of the genome that may harbor rare disease causing variants. Data for these analysis comes from 748 people (503 with LOAD) from the Cache County study on Memory and Aging. This unique population based sample provides great power for linkage as relatedness differs from siblings to distant relatives and complete pedigree information is available for all of the individuals. We will use LD-pruned SNP data from the Illumina Omniexpress BeadChip and pedigree data from the Cache County samples to perform linkage analysis. Quality control and LD-pruning will be con- ducted in PLINK while the Linkage analyses will be conducted using the MERLIN software. Our findings will be reported in the final poster presentation.

Bryce Anderson, Brigham Young University Microbiology and Molecular Biology Antigen presenting cells digest and display peptides from foreign and infected cells on the major histocompatibility complex (MHC) that are recognized by T-cells through their T cell receptor (TCR). The affinity of TCR:peptide-MHC interactions has been shown to be low however, and in order to effectively use a soluble TCR for therapeutics we need to engineer TCRs with increased affinity. To do this, we have designed a single chain TCR (ValphaVbeta) called LLO118 that is specific for a naturally occurring Listeria monocytogenes epitope. Using yeast display, stable mutants that expressed the LLO118 scTCR at higher levels than the wild type on the surface of yeast were isolated and sequenced. In order to improve affinity of LLO118 we are mutating amino acid residues in the complementarity determining regions, sites important for the TCR to bind with the peptide-MHC. We are generating unique libraries of yeast cells with TCRs that have potential affinity mutations and using fluorescently labeled peptide-MHC tetramers to select cells that have TCRs with higher affinity. By repeating this process with the cells that have higher affinity we are working to get a TCR that binds with much higher affinity than the wild type TCR. These high affinity TCRs are promising for further research in connecting them to a cytokine, greatly reducing systemic damage and other complications caused by administration of this cytokine throughout the body. Thus, our goal is to design a high affinity TCR fused to a cytokine that can be tested for therapeutic use in targeting specific cells in the immune response and improving T cell memory.

Spencer Bell, Brigham Young University Physiology and Developmental Biology The hippocampus functions as the memory formation center of the brain. As memories are formed, brain cells in this area undergo changes by which connections between them are either strengthened or weakened, processes known as long-term potentiation (LTP) and long-term depression (LTD), respectively. Receptors located on these cells modulate these processes as they are activated by chemical signals known as neurotransmitters. We sought to examine the effects of a receptor known as G protein-coupled receptor 55 (GPR55) on LTP and LTD in the rodent hippocampus by applying agonists of the receptor, or chemicals that artificially activate it, to brain slices preserved in artificial cerebrospinal fluid. O-1602 is a purported synthetic agonist of GPR55. When we applied O-1602 to rat hippocampal slices during electrical induction of LTP, the magnitude of LTP was decreased when compared to controls. When LTD was induced in the rat hippocampus in the presence of O-1602, no significant difference was observed when compared to controls. Further experimentation involved the application of lysophosphatidylinositol (LPI), a naturally occurring GPR55 agonist, to genetically-engineered knock-out mice which lacked expression of GPR55. LPI is generally considered a more reliable agonist of GPR55, but caused enhanced LTP in wild-type mice which expressed GPR55 when compared with knock-out mice. This inconsistency and other inconsistencies in our data while using O-1602, while perhaps due to other physiological differences between rats and mice, may suggest the possibility that O-1602 activates a receptor other than GPR55. Our further research will seek to investigate this possibility.

Brad Ackerson, Brigham Young University Neuroscience The highjacking by alcohol and drugs of abuse of the mesocortico-limbic system in the brain is responsible for addiction, specifically the ventral tegmental area (VTA) and its projecting dopaminergic neurons to the nucleus accumbens (NAc). Over the course of addiction, a hedonic response is developed from lower than normal levels of dopamine (DA) in which the individual pursues drug-seeking behavior. The current accepted treatment methods for addiction are replacement drug therapies, group therapy, or individual counseling – the prior being associated with additional side-effects and an inability to overcome the hedonic response of the addiction. The aim of this study was to evaluate alternative and natural therapeutics that produce long-term potentiation (LTP) of the neuronal systems involved in order to overcome addiction with minimal to no side-effects. Using fast-scan cyclic voltammetry (FSCV), the effects of baicalein, a flavonoid isolated from the root of Sculletaria Baicalensis, and low-level laser therapy (LLLT) on DA release in the NAc core were evaluated in vitro and in vivo in Wistar rats. Local stimulation evoked in vitro demonstrated that baicalein administration (10, 50, 100 uM) 30 minutes prior to 80 mM ethanol attenuated the DA inhibition of ethanol. DA signals were evoked in vivo in the core of the NAc by electrical stimulation of the medial forebrain bundle (MFB) at the level of the lateral hypothalamus (60 Hz, 60 pulses) in isoflurane anesthetized rats. Both the intraperitoneal (IP) administration of baicalein (1.0 mg/kg) and the administration of LLLT (25 Hz, 630 nm) 30 minutes prior to ethanol (2.0 g/kg) administration IP attenuated the DA inhibition of ethanol. These findings suggest that baicalein and LLLT may prove as effective clinical therapies for addiction.

Kayla Bevard, Brigham Young University Microbiology and Molecular Biology Metabolic diseases, such as obesity and diabetes, are endemic in American society. Mutations in PAS kinase, a recently discovered sensory protein kinase, have been shown to cause Maturity Onset Diabetes of the Young (MODY) in humans (Semplici et al., 2011). In addition, PAS kinase deficient mice, when placed on a high fat diet, display phenotypes related to diabetes including resistance to weight gain, insulin insensitivity and triglyceride accumulation (Hao et al., 2007). PAS kinase consists of a sensory PAS domain that binds to and inhibits the kinase domain (Amezcua et al., 2002). Our model for PAS kinase activation involves the generation of a small molecule ligand that binds to the PAS domain and relieves this inhibition. We are currently engaged in several yeast genetic screens which will identify regions in the full length PAS kinase protein that are essential for either PAS kinase activation or for binding of its substrates. The first screen is based on the ability of PAS kinase, when overexpressed, to rescue a temperature-sensitive mutation in Tor2, the tor2(ts). We have isolated both point mutations and truncations in PAS kinase which alleviate the tor2(ts). These mutations solidify our model for PAS domain inhibition and will identify novel regions involved in PAS kinase regulation. Our second screen uses the yeast 2-hybrid to select for both point mutations and truncations that increase the affinity of PAS kinase for its substrate, Pbp1. These mutations will help identify key regions of PAS kinase utilized in substrate recognition. Finally, we will compare the regions affected by our mutations with the regions of PAS kinase that we have found to be well-conserved throughout evolution. Analysis of these specific genetic regions will help elucidate the molecular mechanisms involved in the regulation and function of PAS kinase, a key player in the development of metabolic disease.

Joseph Moulton, Brigham Young University Physiology and Developmental Biology With the advent of recent mutations in the influenza A viral genome, drugs that previously blocked the proton flux responsible for disassembly of the viral envelope and exposure of viral RNA to the transcriptional machinery of the host cell have become ineffective. Our study of the M2 hydrogen ion channel responsible for this flux has led to a vastly-increased under- standing of the mechanisms behind the conductance activity and potential blockage of these transmembrane tetramers. By embedding M2 proton channel subunits of the S31N mutant strain into liposomal bilayers and suspending these bilayers in the buffers and ionic gradients characteristic of the intracellular environment, we have been able to simulate and observe nor- mal functioning of the influenza A virus. Using these liposomal bilayers, we have developed a series of experimental protocols to test a variety of amantadine- and rimantadine-related drugs for successful blockage of M2 S31N proton conductance. Our research presentation will be centered around the mechanisms of this channel and the favorable results that we have obtained from many of these drugs.

Jonathan Hilbert, Utah Valley University Academic Affairs The Jordan River in Utah has been highly regulated for many years through intense irrigation, channelization, and managed releases from Utah Lake. As the only outlet of Utah Lake flowing north into the Great Salt Lake, it is important to the riparian ecosystem and the surrounding human population as well. The river has a long history of mixed-uses, but it is emerging as a popular recreation site for the numerous adjacent communities. Human interaction on the individual and commercial scale influences the river through development and urbanization. The physical characteristics of the river and its riparian zone can be monitored to understand how the landscape is changing over time. In this study we focus on land cover changes in the riparian zone of the upper one-third of the river flowing out of Utah Lake to what is called “the point of the mountain”. This is the portion of the river that flows in Utah County. From aerial imagery and field observations, we noted alterations in the vegetation within the riparian zone from channelization, riprap, invasive species, or removal for a variety of reasons. We use GIS and aerial imagery to evaluate the land cover change on the Jordan River in Utah County between 1992-2011. Using Anderson’s classification system of land cover, specifically Urban or Built-Up Land, Agriculture, Vegetation, and Barren Earth, we quantified the changes in vegetation within a 100 meter buffer of the river’s wetted channel. While there are areas where little change is observed, areas of greatest change occurred downstream of the outlet, where a number of new communities have been developed in the last decade. As a subset of Vegetation we mapped changed in invasive species, tamarisk and reed canary grass, along the same section of the river within the riparian zone. Urban planning and invasive species removal along the river needs to be further considered as potential future recreation and restoration efforts are advanced on the river.

Licia Kim, Utah Valley University Academic Affairs Utah is a state that was largely settled by immigrants, and among those immigrants were hundreds of Chinese people. For over 70 years, Salt Lake City was home to one of the most prominent Chinatowns in the Intermountain West. Today, Utah is home to over 10,000 Chinese people, but there is no Chinatown in Utah. If the average Utahan is asked “Whatever happened to Salt Lake’s Chinatown?” the answer will invariably be a variation of “Salt Lake had/has a Chinatown?” Yes, Salt Lake City had a Chinatown and this research project answers the question of what happened to it. By exploring existing scholarly works, oral interviews and newspaper articles from the years that Plum Alley, Salt Lake City’s Chinatown, existed, I examined the creation, heyday, decline and eventual demise of Utah’s largest Chinatown. According to my research, the Plum Alley Chinatown disappeared because of a combination of cultural/religious differences, economic pressures, racial issues, and political/legal restrictions. As the significance of China, both to Utah and the United States as a whole, increases, an opportunity is created to increase public awareness of the Chinese experience in Utah’s history. Once this history is known, Plum Alley’s location, in a familiar, near-by location, will provide students in Chinese immersion classes (and their parents) with an opportunity to form a more immediate connection with these distant people. The goal of this research is therefore twofold: 1) to create a research article suitable for publication in a scholarly journal, and 2) to create a PowerPoint presentation and/or traveling historical exhibit on Plum Alley suitable for display at schools, public libraries and other community centers (such as the new South Salt Lake Chinatown shopping center). Simple entrance and exit surveys will allow me to track the effectiveness of the presentation/exhibit to increase visitor awareness of this little known chapter in Utah history.

Buchanan Kerswell, Utah Valley University Academic Affairs Increase in population and wealth in Utah will likely result in increased fossil fuel consumption. Consequently it will lead to more environmental problems, especially air quality and health issues. It is essential to further the research and assessment of renewable energy sources. The objective of this research is to compile, analyze, map and assess energy data from the Utah Geological Survey, Utah Office of Energy Development and Utah Department of Environmental Protection. Our project will give public a clear picture of air quality and energy use coupling with population and economic growth. ArcGIS maps and statistical analysis will be made using the available database. Furthermore, detailed assessments on the development potentials of different renewable energy sources (e.g. solar, wind, geothermal) in Utah will be conducted using ArcGIS. Our preliminary data analysis on fossil fuels indicates that consumption and expenditures have grown over time with population growth. A notable fact is that when expenditures have risen rapidly, consumption tends to decline. The most recent evident periods are during the early 1980s and in the early 2000s, when oil prices were rapidly increasing. Furthermore, the data show that air quality is closely correlated with the quantity of fossil fuel consumed, especially given Utah’s special topography (the valley effect). The data on renewable energy sources have revealed that all renewable energy sources together provide less than 1% of energy need in Utah. Although the growth and development have varied during the last half century, there is a steady growth in geothermal, solar and wind energy over the last decade. Results from ArcGIS mapping will provide useful insights on zoning and assessing potential renewable energy sources in Utah. Renewable energy is the key to our economic growth and clean air in Utah. It is essential that the transition from a primarily carbon-based energy portfolio be to one that includes a greater mix of renewable sources. Further results, analyses and maps will be presented during the meeting.

Andy Thompson, Utah Valley University Academic Affairs The effectiveness of relationship education, especially among predominately young college students, has been a topic of great interest. Given the diversity of family outcomes, more young individuals seek out help for their relationships. Past studies involving relationship education programs have showed that such programs are beneficial (e.g., Halford, et al., 2003). Improvement in couple communication skills was one effect of couples participating in these programs, and even increased relationship satisfaction in some instances (Halford, et al., 2003).

Janeese Stiles, Utah Valley University Academic Affairs Previous studies have shown that high-frequency (HF) ultrasound is sensitive to cell properties such as stiffness and adhesion factors which are a function of protein expression. The goal of this project is to see if HF ultrasound is sensitive enough to detect and differentiate between the five molecular subtypes of breast cancer which are based on protein expression. Since genetic changes precede histological changes in the development of breast cancer, the ability to detect genetic changes (i.e., molecular subtypes) in breast tissue in real time and at the microscopic level will allow surgeons to remove all of the malignant and premalignant tissue during lumpectomies. HF ultrasound personalizes the treatment plan and will be used as a diagnostic technique for precise, image-guided breast cancer surgery. Four breast cancer cell lines with different molecular subtypes and a non-malignant breast cell line will be grown as monolayer cultures. At monolayer confluence, cell and nuclei morphologies of the cell cultures will be determined by phase-contrast microscopy. After microscopy, the monolayers will be ultrasonically tested using a HF ultrasonic test system with a single-element (50 MHz, 6.35-mm) ultrasonic immersion transducer. The resulting ultrasonic waveforms will be analyzed using computational models that simulate the ultrasonic scattering from cells and nuclei as a function of morphology, internal properties, and external properties. The protein expressions associated with the different subtypes will be researched to determine what effects each subtype will have on cell and tissue properties. This method will add a new dimension to pathology and permit more efficient surgical treatment of breast cancer.

Tyson Jones, Utah Valley University Academic Affairs In 2008 the people of the United States and the world were awakened from a dream that huge financial gains can be made at the expense of huge public losses while everything will stay just and fair. Unfortunately, the 2008 economic crash wasn’t the result of just one idea in one sector, but rather a culture within economies; a culture that has not just investment bankers but everyday American and foreign citizens pursuing the same path. This path, that many American and foreign citizens have been enticed by, is a business structure that leaves an individual and their chances of success equal to the chances of failure of those that follow suit, namely Ponzi Schemes. The many people who follow Ponzi Schemes are looking for financial security along with promises of high earnings and early retirement, but are often met with greater debt than they had before simply due to the structure of these Ponzi schemes. For the most part Ponzi schemes have been made illegal in the United States; however, due to certain laws that have been established, Ponzi schemes have been operating under the guise of established businesses known as Multi-level Markets (MLMs). The laws in question are the DSHEA, which has aided MLMs on a national level, and Utah S.B. 0182, which created a loophole for MLMs to operate in large numbers on a State level. Thus a culture of legal positivist views allows the illegal and immoral business practices of MLMs to encourage a culture of harming many to reward a few. This conclusion about MLMs comes from contrasting the structure of MLMs with the moral theory of Immanuel Kant’s Categorical Imperative which requires that all moral actions be held as a universal maxim, and that people are not treated as merely means to an end. The purpose of this research is to assess whether the previous conclusion is in fact true of MLMs in regards to moral business practices through the Categorical Imperative. If after examination the conclusion is found to be true, the DSHEA and Utah S.B. 0182 both need to be revoked in order to begin a change in culture; else large amounts of U.S. dollars, as well as other currencies, will continue to fund illegal Ponzi schemes acting as legitimate businesses and an opportunity to take steps to change U.S. culture on the nature of wealth. In addition, a new culture that allowed for the 2008 financial crisis of large rewards for the few at huge public expenses will continue to grow.

Chase Hansen, Utah Valley University Academic Affairs Purpose

Laurel Thompson, Utah Valley University Academic Affairs Soldiers and non-combatants are at risk of exposure to dangerous aerosols (airborne particles or droplets) in the form of biological agents such as bacteria, toxins, or viruses. The current method for assessing health risk in the field is a moist swath which turns dark upon contact with a biological aerosol. Optical methods are more sensitive to the physical properties of aerosols, and many systems have been developed for optically measuring particle properties. However, they are generally limited to bio-aerosol detection at a single point in space where the system directly samples an aerosol from within the aerosol cloud. The desired solution is a system that can employ remote sensing to measure aerosol properties from a distance. Standoff detection methods allow a much larger area to be measured at once, providing a more general or big-picture view of the aerosols in a given area. There are several ways that standoff optical scattering data can be analyzed for determining aerosol properties. Light scattered by aerosols of known size and composition can be modeled exceptionally well with Mie scattering theory, but the reverse problem determining aerosol properties from the light signals using inverse Mie theory is difficult to solve because a unique set of aerosol properties must be found to correspond to the optical spectra. This is challenging since different combinations of aerosol properties can result in similar spectra. The size distribution, however, has a large effect on the optical signal and may therefore be used to differentiate aerosols. Specifically, biological aerosols have a more narrow size distribution than mineral-based dusts due to genetic limitations. Their refractive indices will also contribute to distinct optical spectra. The hypothesis for this project was that these factors would be sufficient to classify aerosols for risk assessment. Three analysis methods were used to test this hypothesis: Mie inversion with matrix solutions, empirical curve fitting with polynomial functions, and principal component analysis (PCA). Particles suspended in methanol were used as the model aerosol system. A range of particle sizes and compositions were illuminated by a balanced deuterium/halogen light source and spectral measurements from 200-1100 nm were taken. Optical data over a 200-1300 nm range were also collected from a variety of bio-aerosols using an open path remote sensing system at a 30-meter standoff distance.

Chelsea Newsome, Utah Valley University Academic Affairs In the emerging profession of health education there has been a lack of attention on the needs of health education specialists. Recently at Utah Valley University, Dr. Mary V. Brown, and undergraduate students in the Public and Community Health Education department, conducted research focusing on if the needs of health education specialists were being met. Qualitative data collection methods were used to help in needs assessment, planning, goal setting, and quality improvement for both professional organizations and academic institutions. Student Researchers held five focus groups throughout the state of Utah to gather insights from health educators on what they believe are emerging trends, most useful coursework in the academic setting, and professional development needs. The questions used in the focus groups were developed from the assistance of two state professional organizations. The students involved were trained to be moderators and note takers by using guidelines from Krueger and Casey (2000). The data was analyzed using the long table approach outlined by Krueger and Casey (2000). The results showed that the health educators perceived the top emerging trends were social marketing, followed by social media, and a greater focus on primary prevention. As researchers we found the most helpful information for academic institutions would be what the health educators felt were lacking in their educational experiences. The health educators wished that grant writing, computer programs/technical skills/ designing brochures, real life experience/opportunities to apply their knowledge in community settings/practical application classes had been offered in their program of study. With regard to professional development, we found the majority of health educators were supported from upper management to receive continuing education depending on funds. The classes they wanted more of at these continuing education conferences are knowledge in politics, technology, and developing partnerships in the community. This information will be a benefit to both the professional organizations and academic institutions in the state of Utah to improve training of professionals and students alike.

Hallmat Ipaye, Westminster College Marketing Marketers and advertisers allocate a compelling amount of resources to deciphering their target market, however, currently many women express that advertisements targeted towards and portraying women do not represent real women. An increasing disconnect exists between what an average woman actually looks like, thinks, acts and does and how a woman is marketed to in advertisements, specifically in women’s fashion and beauty magazines. Advertisers and marketers make important decisions regarding advertising and marketing without first consulting consumers about finished advertisements. Studies have shown that women do not relate, and often have lowered self esteem after looking at modern fashion and beauty magazines. This research and presentation focuses on categorizing what is important to women over the age of 18 to gain insight on how advertisers and marketers can better represent women in the advertisements of popular fashion and beauty magazines. July 2012 issues of fashion and beauty magazines Vogue, Glamour and Cosmopolitan will be discussed in terms of presence of factors that are important for women to relate to the advertisements in these magazines. The conclusion of these findings will further demonstrate the sales implications of representing real women in advertising from a survey of over 200 women.

Mimi Marstaller, University of Utah Economics During the Progressive Era that stretched roughly from 18771928, the United States faced the rising costs of industrialism. As corporate capitalism expanded and a national market replaced local economies, the role of the federal government changed to include mitigating collective costs by providing public goods. The Progressive Era represents the U.S.’ first national discussion on the role of the state in an industrialized nation. The nation, newly linked by economic ties, faced a collective action problem. I use this historical backdrop to examine economic theories on how societies manage the costs of capitalism. I look at scholarship on collective action, spontaneous order, self-regulation and enforcement within economic systems, and explore how the Progressive Era exemplify or refute the theories on social and economic behavior. I trace the emergence of a national market from pre-industrial, local economies, and examine how in the national context citizenship, the newly powerful nation state and standardized treatment of collective costs played an essential role in establishing the market as the central motivating factor of 20th century American culture. The institutions supporting citizenship and facilitating market participation bolstered capitalism but also required significant oversight by the regulatory bureaucracy established during the Progressive Era. While mainstream economic theory minimizes the role of class interests and power dynamics by assuming freedom of contract and costless enforcement of property rights, recent work in economics invokes sociology and history to understand the barriers to collective action. Today’s most illuminating theories revive the thought processes of the early, classical political economists, and I use the Progressive Era to explore the extent to which their theories on collective cost management describe the case of U.S. industrialization.

Megan Hansen, Utah State University Economics This research represents one chapter out of a larger book written with the help of fellow student researchers at Liberty Source under the direction of Dr. Randy Simmons. The book itself questions the notion common among environmentalists that a balance of nature exists and that governments should take steps to restore that balance when it is upset. This research in particular examines the effects of the Energy Policy Act of 2005, and the subsequent funding of alternative energy start-ups by the federal government in an effort to restore the balance of nature. It includes a detailed case study of Solyndra, a solar power manufacturing company that received a large federal loan from the Department of Energy under the Obama administration only to default a few years later. This case study questions the role of the government in “picking favorites” when it comes to alternative energy, and argues that failure is likely when this occurs due to imperfect information and the tendency for politics to play too large a role in decision-making.

Joshua Blume, Utah State University Economics and Finance Studies of expatriates in a number of industries have suggested that acculturation plays a role in how individuals re-adapt to their home country after working abroad. This study applies acculturation and repatriation frameworks to returned Mormon Missionaries (who have also spent significant time away from home and family). Qualitative and quantitative results suggest that re-adaptation to home, family and school are affected in part by cultural components of the mission experience. Recommendations are made to assist “expatriate missionaries” in the re-acclimation process.

Whitney Evans, Brigham Young University Communications The United States adopted a freedom of information law earlier than the United Kingdom, but the latter has surged ahead with its adoption of an Information Commissioner’s Office, well equipped to handle complaints and mediate in complex situations. This article delves into the attitudes of those who are intimately involved with freedom of information laws: journalists, lobbyists, campaigners, advocates and government officials. This qualitative research showed a similar attitude at a government level in both countries, namely, a hesitance of government officials to warm up to the law. The Information Commissioner in the United Kingdom and the Office of Government Information Services in the United States are essentially limited to recommendation and mediation services. The United States, initially progressive in its open government laws, has lagged behind many other nations in terms of disclosure. Because the law is nearly 50 years old, the Freedom of Information Act here is often taken for granted. Complacence, rather than outright defiance, obstructs successful implementation of this law. The United Kingdom has the lingering legacy of an Official Secrets Act obstructing what would otherwise be a clean slate on which to build their government disclosure laws. The key to successful utilization of freedom of information laws in both countries lies in a shift in each country’s culture, instigated by a marked change in the stories being told.

Michael Alexander, Utah Valley University Academic Affairs The Tintic Mining District is located in central Utah on the eastern edge of the Basin and Range Province. This area experienced significant hydrothermal alteration associated with volcanism in the early Cenozoic Era. This hydrothermal alteration was productive of sulfide ore deposition along fissure veins, including ores of copper, gold and silver. Previous aeromagnetic surveys showed that porphyry copper assemblages are associated with mappable anomalies in the Earth’s total magnetic field. The magnetic anomalies were interpreted as resulting from buried intrusive igneous rocks associated with the porphyry copper assemblages. The objective of this research is to map buried fissure veins on property owned by NorthStar Mine using a ground-based survey of anomalies in the Earth’s total magnetic field. This study will be the first geophysical mapping of fissure veins in this area. Previous work by the author and other Utah Valley University students showed that total magnetic field anomalies could be used to map halloysite clay deposits, the copper sulfide deposits associated with buried basaltic dikes, and a wide variety of igneous rock bodies including buried bodies of quartz monzonite, rhyolite and tuff. Because the igneous rocks are considered to be the source of hydrothermal fluids, further mapping of the distribution of igneous rocks could give some insight into the migration of fluids that deposited ore in fissure veins. The ground-based magnetic survey will be carried out using the Geometrics G-856 Proton Precession Magnetometer. Magnetic susceptibilities of outcrops will be measured using the handheld SM-10 Magnetic Susceptibility Meter. Rock samples will also be collected for crushing and more precise measurement of magnetic susceptibility in the lab using the Bartington MS3 Magnetic Susceptibility Meter. Mapped magnetic anomalies will be compared with possible subsurface rock bodies using the IX2D Magnetic Interpretation Software. All necessary equipment is currently owned by the Department of Earth Science. This research is being carried out in cooperation with NorthStar Mine. Results will be reported at the meeting.

Alex Dutson, Utah Valley University Academic Affairs Introduction:

John Maynes, Utah State University Elementary Education Research on gifted education has shown that expertise development requires learning very basic skills to a high level (Bloom 1986). As a university education is meant to provide students with opportunities to develop expertise in a given field, it is imperative that universities provide learners with opportunities to learn very basic skills to a high level. However, do students receive adequate opportunities to learn the skills necessary to develop expertise? Do some students receive more opportunities than others? This study seeks to answer these questions by surveying honors and non-honors students to determine their perceptions respectively of opportunities to develop expertise in their chosen field of study. By matching each honors student with a non-honors student in the same class, the survey aims to evaluate the difference between the perceptions of honors students and non-honors students in the same class. Scager, et al indicate that honors students are more likely to develop expertise than non-honors students at a university (2011). Thus the hypothesis of this study is honors students receive more opportunities for expertise development than non-honors students.

Andres Chavez, Brigham Young University Education The purpose of this research is to explore the current status and condition of the public and private education k-12 in Ecuador and analyze the implications that recent policy changes made by the Ecuadorian Ministry of Education hold for the future role of K-12 schools in the country. In order to do this, I first met with the Minister of Education and received information regarding national test scores of schools in six provinces, the provinces being Guayas, Santa Elena, El Oro, Manabí, Azuay, and Pichincha. I then visited four different types of schools in each of those provinces, the types being public, municipal, fiscomisional, and private. In each of these schools, I held an interview with the principal as well as a few selected teachers, and observed the general condition of the school grounds and facilities. I found that the majority of the public schools are overpopulated, while the private schools for the poor are disappearing due to the diminishing number of students who are enrolling in their programs. I propose that the reforms that the Ministry of Education has put in place will be more effective in improving education if the number of students in each public classroom is reduced to a manageable amount. This can be achieved by the government providing subsidies and financial aid for more students to attend private schools.

Brandon Dollar, Utah Valley University College Success Studies Student retention and persistence to graduation are two issues that receive significant attention and allocation of financial and human resources in higher education. A recent study (Creighton, Creighton, & Parks, 2010) stated that 26% of new freshmen do not matriculate their sophomore year. Consequently, many institutions within higher education have placed emphasis on the first-year experience (FYE). In response to the issues that lead freshmen to dropout, FYE program outcomes generally include student self-awareness (Krause & Coates, 2008), learning academic skills and strategies (Crisp & Cruz, 2010; Schrader & Brown, 2008), connecting students to campus (Zhao & Kuh, 2004; Bell, 2012) and social support (Tinto, 2009; Wilcox, Winn & Fyvie-Gauld, 2005). However, research shows that most institutions approach FYE programming with a “piecemeal approach” (Krause, Hartly, James, & McInnis, 2005) and do not take a “whole-of-institution” approach (Kift, Nelson, & Clark, 2010) where student retention and persistence are part of the fabric of the entire institution. One of the aspects of FYE programming is peer mentoring. Peer mentoring emerged within the FYE programs to facilitate these program outcomes and ultimately, student retention. In fact, an early literature review (Jacobi, 1991) on mentoring revealed four identifiable outcomes of mentoring, three of which claimed to be applicable to peer mentoring and successful fulfillment of FYE outcomes. Some peer mentoring programs emerge from student affairs (Lopez, Johnson & Black, 2010) while other programs originate from academic affairs (Colvin & Ashman, 2010). Aside from the differing origins of peer mentoring programs, research identifies six types of mentoring programs, five of which claim to be applicable to peer mentoring (Karcher, Kuperminc, Portwood, Sipe, & Taylor, 2006). However, there still appears to be no universal approach to peer mentoring in higher education. Specifically, research has yet to reveal a peer mentoring program that comprehensively synthesizes the great foundational work of Jacobi (1991) and Karcher and his colleagues (2006) and maintains the necessary theoretical alignment proposed in recent literature (Hall & Jaugietis, 2011; Crisp & Cruz, 2010) within a holistic and integrated institutional approach to student success and retention.

Jared Crossley, Brigham Young University Education This research project was to make a film about Lloyd Alexander, one of America’s most influential authors of fantasy for young readers. Best known for his Chronicles of Prydain, including the 1969 Newbery Award winning “The High King”, Alexander won numerous awards and was translated into over 20 languages. This study includes interviews with his editors, close friends, and professionals in the children’s literature community as well as archival photographs from his life. The research actually culminated in two documentary films exploring the life and writings of Lloyd Alexander, one ten minutes long and the other an hour in length. These films already have created much interest in Alexander and his works, reaching long-time Alexander fans, as well as helping to establish some new readers of his work.

Megan Curtis, Utah Valley University Academic Affairs Capitol Reef Field Station (CRFS) is located in south-central Utah within Capitol Reef National Park (CARE). Due to its arid climate and diverse geology, many plant species found within CARE have unique adaptations that are sensitive to disturbance. Cryptobiotic crusts, which play a vital role to the health of vegetation by stabilizing soils, cycling nutrients, and reducing erosion, are extremely sensitive to disturbance and can take many years to recover after being damaged by footprints. In addition, the spread of invasive species can harm native vegetation by competition for resources. Since CRFS’s founding in 2008, it has been frequented by visitors who come to learn about CARE’s natural and cultural history. Consequently, various trails and dirt roads surrounding CRFS may be a source of human disturbance and spread invasive species. Another source of disturbance is cattle that graze in this area on their route through CARE twice each summer. The objective of this study is to characterize the vegetation surrounding CRFS and determine the present level of human and domestic impact on this vegetation. Our specific questions were; (1) Is the level of human disturbance associated with plant community structure and proximity to CRFS, (2) Which communities have the highest levels of cattle/human disturbance?, (3) How does community structure vary by vegetation type? To address these questions, two 100-m transects with differing proximities to CRFS were established in each of four vegetative communities’ Pinyon-Juniper, Big Sagebrush, Riparian, and Grassland. Species frequency, cover, and disturbance (density of tracks within a quadrat) were recorded within each transect using a nested plot frequency design -four nested subplots ranging from 0.25 4m2. To account for seasonal variance, data were collected in four sampling periods throughout growing season. To characterize community abiotic factors, slope, aspect, and soil attributes were measured for each transect. To analyze the data, we ran multivariate analysis, including Non-metric Multidimensional Scaling (NMS), and Multi-response Permutation Procedure (MRPP). The two-dimensional NMS solution explained 80.1% of variability in community structure.

John Maynes, Utah State University The Center for the School of the Future In the early history of the United States, the Founders of our nation set aside vast amounts of land which were to be used to support public schools. Starting in 1785, lands were dedicated to support schools and thereby provide public education to new settlers in the “Northwest Territory.” Further legislation in 1787 reinforced this granting process with the language, “Religion, morality, and knowledge being necessary to good government and the happiness of mankind, schools and the means of education shall forever be encouraged.” These actions were championed by many of the same men who would be influential in writing the Constitution, most notably Nathan Dane of Massachusetts. However, after the first lands were granted, many new states were admitted to the United States without granting lands for schools. It seemed that the idea for granting school lands had been forgotten. However, in 1803 Ohio was admitted as a state, and the land grants for public schools were renewed. Since that time, every state admitted to the Union was granted school trust lands. The purpose of this study is to address the following questions: What resources were used to support public education? How did attitudes toward these resources evolve from the beginning of our country to now? Based on preliminary findings, we can see that attitudes towards school trust lands have varied throughout history and the policies and resources used to support them have been equally variable. By looking at school trust lands and school permanent fund values, I hope to evaluate the attitudes of decision makers toward education over the course of American history. Using historical records such as legislation, Congressional annuls, and personal correspondences to evaluate personal attitudes of policymakers, this study will identify determinants that supported the unique attitudes and policies surrounding school trust lands.

Keely Glade, Utah Valley University Academic Affairs Cytozyme Laboratories, Inc., Salt Lake City, UT is an agricultural company that provides a range of products for large food crop farming and animal production. In order to provide data to prospective buyers on their products’ effectiveness in improving crop yields and health, they chose to study the expression levels of several different genes using Arabidopsis thaliana as their model organism. These genes include: 1) At2g14610 encoding Pathogenesis Related gene 1 (PR1), which assists in plant pathogen defense, 2) At2g29350, Senescence-Associated Gene 13 (SAG13), and 3) At2g30770, Cytochrome p450, Family 71, Subfamily A, Polypeptide 13 (CYP71A13). A. thaliana leaves were treated with a proprietary substance implicated in plant health and potential crop yield. Treated and untreated leaf homogenates were used to create cDNA from purified RNA for the quantitative real-time PCR (qRT-PCR) assays. The qRT-PCR assays were performed on the cDNA generated from PR1, SAG13, CYP71A13, with the 40S ribosomal subunit as the internal control, on an ABI 7500 Fast Real Time System using gene-specific primers and SYBR green as our reporter molecule. The fold change, a value that is a relative comparison between the non-treated and treated samples, for each gene was calculated. The results showed clear up regulation of PR1, SAG13, and CYP71A13 compared to the 40S ribosomal subunit internal control. Future experiments include qRT-PCR and microarray analyses for 11 other proprietary treatments provided by Cytozyme.

Jacob Robinson, Brigham Young University Mechanical Engineering Figure skating is a competitive sport that requires athletes to practice up to 5 days a week year round performing 50 to 100 jumps per day. This results in high, repetitive impact forces on the skater’s body which may lead to overuse injuries. While the negative effects of figure skating are well documented, the cause of these injuries is still unclear because the complexity of artistic figure skating limits current instrumentation from accurately measuring impact forces. This project has sought to fill this void by developing a force measurement system that will allow the figure skater to perform their jumps without any hindrance while accurately measuring the magnitude of the impact forces in the vertical and horizontal directions. Using strain gauges attached to the stanchions of the ice skate combined with a data collection system that attaches to the bottom of the boot, we have developed a prototype that accurately measures the forces produced in the ice skate. This will lead to a fully developed ice skate measurement system which will be used by researchers to investigate the impact forces generated in figure skating jumps and landings.

Connor George, Utah State University Electrical and Computer Engineering The SABER instrument, aboard the TIMED satellite, measures optical data regarding parameters of the Earth’s atmosphere with respect to altitude. Approximately once per minute, SABER performs a limb-scan measurement on the Earth’s atmosphere from which altitude emission profiles of key atmospheric gasses, including hydroxyl at wavelengths of 1.6 μm and 2.0 μm, are derived. Most hydroxyl profiles within the SABER dataset contain a single peak in the airglow altitude profile centered near an altitude of 87 km, but a significant portion of the profiles display two or more local maxima. MATLAB code was written to analyze the geophysical and temporal global distribution of the multiple-peak profiles. Graphs have been created which display relationships between the percentage of multiple-peak profiles and the local time, the cardinal orientation of the SABER device, and the latitude and longitude at which the atmospheric profile was measured. Patterns have been observed in multiple-peak profile distribution with respect to these variables. Possible causes of the multiple-peak occurrences in the hydroxyl altitude profiles include waves, geometrical effects of the SABER instrument, and/or chemistry of the atmosphere. In addition to graphing software, analysis software was written which counts the number of peaks present in any given altitude profile, and which ascertained the percentage of profiles displaying multiple-peak characteristics. A small (<1%) portion of hydroxyl altitude profiles were found to have abnormal distributions due to erroneous or noisy data collected by SABER. Software has also been written to remove such exceptions from the dataset. Additional investigation into the relationship between multiple-peak occurrences and cardinal direction orientation of the SABER device is required in order to further identify the causes for multiple peak profiles. An investigation into seasonal patterns for multiple-peak profiles is to be conducted. As the dataset grows, exception software will be updated to identify invalid altitude profiles. Also, ozone has been found to have multiple-peak altitude profiles similar to those of hydroxyl, and studies complementary to those performed on hydroxyl altitude profiles will be performed on ozone.

Derek Chang, University of Utah Bioengineering Atrial fibrillation (AF), the most common cardiac arrhythmia, is a rapid, irregular heart beat arising from uncontrolled and asynchronized electrical activation in the atria. This disruption of the normal electrical signaling hinders the contraction of the heart, leading to decreased blood flow, possible clot (thrombus) formation, and an increased risk of stroke. The left atrial appendage (LAA) is a small muscular pouch of highly variable anatomy within the left atrium. The LAA plays a prominent role in thrombus formation in patients with AF because of decreased blood flow within this structure. Thus, we hypothesized that the shape of the left atrial appendage is different in AF patients with a documented history of stroke. We used statistical shape analysis to determine which LAA shape variations contribute to stroke based on a cohort of AF patients who had both MRI and CT scans and a documented history of stroke. We manually delineated the boundaries of the LAA from each patient’s CT and MRI scans to analyze the resulting LAA segmentations for shape variations across imaging modalities and history of stroke. The results showed that patients who have AF and a history of stroke have an LAA with a narrower insertion site into the left atrium and are larger in size. In contrast, patients who have AF, but no history of stroke, have an LAA with a wider insertion site, which are smaller in size. By isolating specific LAA shape variants indicative of an underlying risk of stroke, we can use this shape classification scheme to better tailor AF therapies to each individual patient.

Autumn Pando, Brigham Young University Mechanical Engineering The wrist is one of the most common sites for joint injury. Over two-thirds of 75,000 annual repetitive joint injuries occur at the wrist. Excessive or abnormal wrist forces are thought to be one of the main contributing factors, yet no characterization of normal wrist forces exists. The purpose of this research is to fill this lack by creating a systematic, quantitative characterization of wrist forces and torques experienced in daily life. This database will aid further research in developing better and more personalized treatments as well as improving design considerations for human-machine interfaces. Ten healthy subjects participated in the experiment. Subjects performed 25 activities representative of daily life (e.g. hygiene maintenance, food preparation, using technology). Electromyographic (EMG) sensors recorded wrist muscle activity and electromagnetic motion sensors recorded wrist kinematics. Each subject performed a calibration task prior to the experimental protocol to determine the proportionality constant between EMG activity and torque. Wrist force and torque were determined from EMG activity using a constant of proportionality (identified by calibration), muscle length, and muscle velocity. Co-contraction was computed from torque. Wrist muscle usage, forces, torque magnitudes, torque angles, and percentage of co-contraction at varying levels of contraction were characterized. The results indicate muscle use, forces, and torques are unevenly distributed.

Mitchell Dabling, Utah State University Civil and Environmental Engineering Water management and flood control are essential elements of civilization. Linear weirs (e.g. ogee crest, sharp crested, and broad crested weirs) are often used in irrigation channels or reservoir spillways to regulate the discharge and upstream water level during flood flows. As hydrologic data sets increase in size and accuracy, the highest probable maximum flood (PMF) discharge is becoming increasingly more accurate, and in many cases much larger than previous estimates. Because of this, an older weir may need to be rehabilitated to ensure it can pass the updated PMF discharge safely without upstream flooding. A nonlinear weir (e.g. labyrinth or piano key weir) can replace a linear weir in a channel or spillway to pass significantly more discharge without requiring increased channel width. The Utah Water Research Laboratory at Utah State University, with the help of Utah Mineral Lease Funds, has developed and published design data for multiple configurations of nonlinear weirs. In 2012, the Utah Division of Water Resources used this data to design a labyrinth-style nonlinear weir that will replace the spillway currently in use at Millsite Reservoir in Emery County. This rehabilitation project will significantly decrease the flooding potential of the surrounding area.

Kay (Beau) Freckleton, University of Utah Mechanical Engineering Current quad-rotors provide excellent maneuverability and opportunity for data collection in large scale areas such as agriculture, but lack the capability to maintain flight for an extended period of time. This is due primarily to a lack of energy supply, requiring operators to replace the battery source before the quad-rotor completes its designated purpose [1]. In this paper, we introduce a mechanism to enable flying robotic rotorcraft, such as quadrotors and helicopters which utilize vertical takeoff and landing, to perch similar to a bird. The mechanism is passive, using only the weight of the rotorcraft for actuation. Such a mechanism will dispel the need for multiple batteries by allowing the quadrotor to perch amid its designated flight course, recharge using solar energy, and complete data collection over large scale areas in less time. In previous research to this same end, biomimetic approaches were pursued, resulting in designs that looked similar to the legs and feet of birds. The design in this paper utilizes a Sarrus mechanism to convert rotorcraft weight into perch grip. We began by designing the mechanism for a range of cylindrical perch sizes. Using MATLAB, we developed a program to optimize the various mechanism dimensions needed to perch within this range while also maximizing the mechanical advantage of grip force. Using SolidWorks, a 3-dimensional model was created and manufactured with these dimensions. In testing, the mechanism successfully allowed a small RC helicopter to perch on a 4cm diameter rod with some resistance to external forces. However, in crash tests, the mechanism was unable to withstand certain moment forces and developed large fractures. Further research will focus on decreasing these moment forces’ ability to weaken the mechanism while optimizing perching capability.

Kimberly Uchida, University of Utah Bioengineering and Oncological Sciences Programmed cell death 4 (PDCD4) loses its function as a tumor suppressor when co-expressed with a specific binding partner, protein arginine methyltransferase-5 (PRMT5). A better understanding of the regulation of PDCD4-PRMT5 interaction may lead to cancer therapies targeted at restoring the tumor suppressive function of PDCD4. Using Xenopus laevis (frog) eggs to generate extract trapped in either interphase or mitosis, we found that PDCD4-PRMT5 interaction is regulated by the cell cycle. Full-length PDCD4 bound PRMT5 more robustly in interphase than in mitosis. However, a truncated version of PDCD4, that retained the PRMT5 binding site, bound PRMT5 equally in interphase and mitosis. These results indicate that there may be a component of full-length PDCD4 that occludes the PRMT5 binding site in mitosis. Furthermore, we found that both full-length and the truncated PDCD4 are preferentially phosphorylated in mitosis, but preferentially methylated in interphase. From these results we speculate that phosphorylation of PDCD4 in mitosis allows PDCD4 to fold upon itself and effectively block the PRMT5 binding site. Additionally, phosphorylation may prevent methylation even when PRMT5 can bind PDCD4, explaining the lack of PDCD4 methylation in mitosis. Such an inhibitory mechanism may be useful in therapeutically restoring the tumor suppressive function of PDCD4. Future research will be aimed towards completing our understanding of PDCD4-PRMT5 interaction in the cell cycle, such as proving our model in human cells.

Colin Cox, Weber State University Economics Acceptance into the Organization for Economic Co-Operation and Development (OECD) can be interpreted as a sign that a country has achieved a level of high economic development. The pathways leading to becoming an OECD country are as diverse as the countries within this organization. The most recent country to join this elite organization is the small eastern European country, Estonia. Besides being the most recent country to be inducted into the OECD Estonia has another unique characteristic, it is the only OECD country to have belonged to the Soviet Union. Estonia’s relatively new independence gives researchers an extraordinary opportunity. We are able to track this country’s economic progress after its policies and institutions were essentially wiped clean upon gaining independence in 1991. In this study I will investigate what macroeconomic devices Estonia has used to progress further than other former Soviet States. In order to do this I will compare key economic indicators and policies for three former Soviet countries with similar economies; Estonia, Latvia, and Lithuania. I will draw connections between economic policies implemented and correlating empirical indicators. After analyzing the above mentioned parameters I will provide a summary of the successes and shortcomings experienced by Estonia’s economy and make relevant suggestions.

Johonna Sheldon, Southern Utah University Agriculture Science Scotch Thistle (Onopordum acanthium), Musk Thistle (Carduuas nutans) and Bull Thistle (Cirsium vulgare) are invasive species that produce large quantities of seeds that remain viable for long periods of time. Collections were made of the species from various locations. Five distinct stages of growth were determined. Samples were collected and labeled with the maturity stage of each seed pod recorded. Tetrazolium, cut, and pop tests will be used to help indicate seed viability. I hypothesize that different stages of maturity will have varying degrees of viability as determined by tests. Furthermore I predict later stages will have the most overall viability and the pop test will positively correlate with the tetrazolium and cut tests. The results are in progress.

Scott Hoopes, Dixie State University Business Hybrid Social Enterprise Businesses are companies that sell products and donate a portion of their proceeds to a social cause. I submit that these types of businesses will become the patterns of marketing and business organization of the future because they are able to fund their social undertakings from the revenue of the products they sell, and be sustained by sales rather than depending on donations to fund their endeavors. The reason this model is successful is because many people throughout the world want to make a difference but rarely take action to put that change into effect. Hybrid Social Enterprise Businesses are able to make a difference in the world through their donations yet they have their revenue from product sales to run the day-to-day business. These items such as TOMs shoes, People Water, and comparable companies are becoming status symbols for socially conscious people worldwide. Not only are these items “fashionable” or “stylish” they are giving consumers the feeling that they have made a difference in somebody else’s life by making a purchase. By comparing and analyzing data from a variety sources and primary research I will be able to support my hypothesis that Hybrid Social Enterprise Businesses are a growing trend of business organization and marketing and will continue to grow into the future.

Kelsey White, Utah State University Economics and Finance California is endowed with some of the United States’ most beautiful natural landscapes. It also lies atop significant energy resources. While preserving natural amenities and developing energy are sometimes considered mutually exclusive endeavors, the reality is that most counties throughout California have developed both of these rich resources. While the ratios between amenities and energy differ, almost all counties with available opportunities have developed both to some extent. This paper compares and contrasts the balance between energy and amenities in three California counties. Monterey County is economically focused on agriculture and amenities, but has a strong potential for developing its shale resources, and some extraction has already begun. Ventura County also boasts plentiful natural amenities, but engages in significant oil production, particularly offshore production. Kern County is economically dependent upon oil extraction, but still maintains an active amenity sector. The fact that all of these counties have opted for a mixed economic portfolio balancing energy and recreation demonstrates that the two activities are not mutually exclusive, but rather that counties already opt for some mixture of the two. The three counties are compared on several key economic indicators such as per capita income and unemployment by using compiled US Census Bureau data. Counties with a mixed economic portfolio enjoy higher economic outcomes than those counties that focus more exclusively on either natural amenities or energy extraction.