2020 Abstracts
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Effects of Indigenous Diet and Location on Hemoglobin Levels of Ghanaians
Gaona-Partida, Paul; Chan, Julian; Aguilar-Alvarez, David (Weber State University)
Faculty Advisor: Chan, Julian (Weber State University, Mathematics); Aguilar-Alvarez, David (Weber State University, Exercise and Nutrition Sciences)
PURPOSE/HYPOTHESIS:
Low hemoglobin (HB) levels are used to indicate anemia, which increases your risk for contracting infectious diseases and overall mortality. The rate of iron deficiency anemia in Ghana is more than triple the world average, making this condition a main health concern for the country. In this study, we sought to identify the influence of location and iron consumption on HB levels of Ghanaians.
METHODOLOGY:
Food frequency questionnaire was given to 140 participants in 5 different locations of Ghana (Jamestown, King Tower, Mole, Larabanga, University of Ghana). All food was classified as low, medium, or high iron content according to the USDA food database. Participants were categorized as adequate or inadequate iron consumers according to this classification. ANOVA and t-test analysis was conducted to determine the differences in hemoglobin level means. P-value was set at µ0.05 and HSD was used as the post-hoc test.
RESULTS/PREDICTED RESULTS:
Mole National Park population had higher HB (µ=13.3 ± 2.51) compared to Jamestown (µ=12.1 ± 1.97) (p=0.034) and Larabanga (µ=12.0 ± 1.97) (p =.032). Individuals classified as high iron consumers had significantly higher HB that their low iron consumers counterparts (µ=13.8 ± 2.42 vs µ=12.1 ± 1.97, p=0.001).
CONCLUSION:
We were able to identify foods associated with increased Ghanaians HB. Mole had higher access to iron-rich foods such as game meat, which was reflected in their HB levels. This study illustrates the importance of promoting consumption of indigenous iron-rich foods in the current Ghanaian diet to prevent iron deficiency anemia in this population.
Faculty Advisor: Chan, Julian (Weber State University, Mathematics); Aguilar-Alvarez, David (Weber State University, Exercise and Nutrition Sciences)
PURPOSE/HYPOTHESIS:
Low hemoglobin (HB) levels are used to indicate anemia, which increases your risk for contracting infectious diseases and overall mortality. The rate of iron deficiency anemia in Ghana is more than triple the world average, making this condition a main health concern for the country. In this study, we sought to identify the influence of location and iron consumption on HB levels of Ghanaians.
METHODOLOGY:
Food frequency questionnaire was given to 140 participants in 5 different locations of Ghana (Jamestown, King Tower, Mole, Larabanga, University of Ghana). All food was classified as low, medium, or high iron content according to the USDA food database. Participants were categorized as adequate or inadequate iron consumers according to this classification. ANOVA and t-test analysis was conducted to determine the differences in hemoglobin level means. P-value was set at µ0.05 and HSD was used as the post-hoc test.
RESULTS/PREDICTED RESULTS:
Mole National Park population had higher HB (µ=13.3 ± 2.51) compared to Jamestown (µ=12.1 ± 1.97) (p=0.034) and Larabanga (µ=12.0 ± 1.97) (p =.032). Individuals classified as high iron consumers had significantly higher HB that their low iron consumers counterparts (µ=13.8 ± 2.42 vs µ=12.1 ± 1.97, p=0.001).
CONCLUSION:
We were able to identify foods associated with increased Ghanaians HB. Mole had higher access to iron-rich foods such as game meat, which was reflected in their HB levels. This study illustrates the importance of promoting consumption of indigenous iron-rich foods in the current Ghanaian diet to prevent iron deficiency anemia in this population.
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Inducible disruption of endothelial cell ceramide biosynthesis: Vascular implications
Thompson, Lauren; Ramous, Caroline; Ly, Kellsey; Luu, Kiana; Margetts, Alex; Warren, Tahno; Tippetts, Trevor; Choi, Ran Hee; Symons, JD (University of Utah)
Faculty Advisor: Symons, J. David (University of Utah, Nutrition and Integrative Physiology)
Type II diabetes mellitus (T2DM) is an epidemic worldwide. Cardiovascular complications (e.g. endothelial dysfunction and hypertension) are associated with T2DM. T2DM affects the quality of life for the patient and their caregivers, and the costs for treating cardiovascular complications are unsustainable. An urgent need exists to elucidate new therapeutic targets for intervention. Our laboratory is interested in defining the contribution from the sphingolipid ceramide. We reported earlier that arterial dysfunction and hypertension that otherwise develop in mice that consume an obesogenic diet is attenuated by pharmacological inhibition of ceramide using myriocin and by germline haploinsufficiency for dihydroceramide desaturase (DES1), an enzyme required for ceramide biosynthesis. However, each study had limitations. Myriocin improved systemic glucose homeostasis, and DES1 inhibition elevated dihydroceramides, both of which could impact arterial function. In the present study, we used a novel murine model to inhibit the rate-limiting enzyme responsible for ceramide biosynthesis (serine palmitoyl transferase light chain 2; Sptlc2) specifically in endothelial cells (ECs). We hypothesized that EC specific inhibition of ceramide biosynthesis would preserve arterial function in obese mice. Six-week-old male mice with intact Sptlc2 (wild-type; WT) and EC specific deletion of Sptlc2 (iecSptlc2KO mice) consumed either standard (CON) or high fat diet (HFD) for 14 weeks. qPCR results indicated Sptlc2 was knocked down > 80% in ECs but not media and adventitia from iecSptlc2KO vs. WT mice. In general, results were similar between WT and iecSptlc2KO mice concerning glucose, insulin, and pyruvate tolerance tests (indicating intact glucose homeostasis) and lean mass, fat mass, and fluid mass (indicating body composition was unaltered). Of note, intraluminal flow-mediated vasodilation was greater in femoral arteries from iecSptlc2KO vs. WT mice that consumed high-fat chow. Preventing ceramide biosynthesis specifically in ECs from mice that consume an obesogenic diet might be vasculoprotective.
Faculty Advisor: Symons, J. David (University of Utah, Nutrition and Integrative Physiology)
Type II diabetes mellitus (T2DM) is an epidemic worldwide. Cardiovascular complications (e.g. endothelial dysfunction and hypertension) are associated with T2DM. T2DM affects the quality of life for the patient and their caregivers, and the costs for treating cardiovascular complications are unsustainable. An urgent need exists to elucidate new therapeutic targets for intervention. Our laboratory is interested in defining the contribution from the sphingolipid ceramide. We reported earlier that arterial dysfunction and hypertension that otherwise develop in mice that consume an obesogenic diet is attenuated by pharmacological inhibition of ceramide using myriocin and by germline haploinsufficiency for dihydroceramide desaturase (DES1), an enzyme required for ceramide biosynthesis. However, each study had limitations. Myriocin improved systemic glucose homeostasis, and DES1 inhibition elevated dihydroceramides, both of which could impact arterial function. In the present study, we used a novel murine model to inhibit the rate-limiting enzyme responsible for ceramide biosynthesis (serine palmitoyl transferase light chain 2; Sptlc2) specifically in endothelial cells (ECs). We hypothesized that EC specific inhibition of ceramide biosynthesis would preserve arterial function in obese mice. Six-week-old male mice with intact Sptlc2 (wild-type; WT) and EC specific deletion of Sptlc2 (iecSptlc2KO mice) consumed either standard (CON) or high fat diet (HFD) for 14 weeks. qPCR results indicated Sptlc2 was knocked down > 80% in ECs but not media and adventitia from iecSptlc2KO vs. WT mice. In general, results were similar between WT and iecSptlc2KO mice concerning glucose, insulin, and pyruvate tolerance tests (indicating intact glucose homeostasis) and lean mass, fat mass, and fluid mass (indicating body composition was unaltered). Of note, intraluminal flow-mediated vasodilation was greater in femoral arteries from iecSptlc2KO vs. WT mice that consumed high-fat chow. Preventing ceramide biosynthesis specifically in ECs from mice that consume an obesogenic diet might be vasculoprotective.
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Giving the VIP Treatment to Prevent Missed Injuries After a Fall
Winters, Blaine; Dustin, Tracy; Escobar, Jeana; Ostlund, Megan (Brigham Young University)
Faculty Advisor: Blaine, Winters (Brigham Young University, Biology)
Background:
Evaluation of patients who have fallen varies significantly between nurses as well as health care facilities. In many cases, injuries go unrecognized or their identification is delayed due to poor or incomplete assessments and follow-up.
Purpose:
The purpose of this project was to design a standardized post-fall assessment for geriatric patients residing in long-term care and community settings.
Methods:
A literature review revealed that in the past 10 years, very few studies were conducted on post-fall assessments, and the majority of these studies were conducted outside of the United States. Due to the lack of current literature on the subject, the Advanced Trauma Life Support algorithm was used as a framework for the development of the post-fall assessment.
Outcomes:
A post-fall assessment evaluation was developed which includes the production of a standardized post-fall assessment flowchart, accompanied by a documentation guide. A training video was also produced to illustrate the use of the assessment tools and to allow nurses to practice their new skills.
Implications for Practice:
The standardized post-fall assessment tools will lead to more thorough evaluation and follow-up of patients who have fallen in long-term care or the community setting. This will lead to more rapid treatment of identified injuries as well as fewer missed injuries.
Teaching Methods:
Participants will receive training on the post-fall evaluation method, how it was developed and how it will be implemented.
Faculty Advisor: Blaine, Winters (Brigham Young University, Biology)
Background:
Evaluation of patients who have fallen varies significantly between nurses as well as health care facilities. In many cases, injuries go unrecognized or their identification is delayed due to poor or incomplete assessments and follow-up.
Purpose:
The purpose of this project was to design a standardized post-fall assessment for geriatric patients residing in long-term care and community settings.
Methods:
A literature review revealed that in the past 10 years, very few studies were conducted on post-fall assessments, and the majority of these studies were conducted outside of the United States. Due to the lack of current literature on the subject, the Advanced Trauma Life Support algorithm was used as a framework for the development of the post-fall assessment.
Outcomes:
A post-fall assessment evaluation was developed which includes the production of a standardized post-fall assessment flowchart, accompanied by a documentation guide. A training video was also produced to illustrate the use of the assessment tools and to allow nurses to practice their new skills.
Implications for Practice:
The standardized post-fall assessment tools will lead to more thorough evaluation and follow-up of patients who have fallen in long-term care or the community setting. This will lead to more rapid treatment of identified injuries as well as fewer missed injuries.
Teaching Methods:
Participants will receive training on the post-fall evaluation method, how it was developed and how it will be implemented.
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Developing Antibodies for Studying Structures and Functions of Polycystic Kidney Disease Proteins
DeNiro, Adara; Cao, Erhu; Wang, Qinzhe; Wang, Jinliang (University of Utah)
Faculty Advisor: Cao, Erhu (University of Utah, School of Medicine)
The kidneys are responsible for several essential bodily functions critical to our survival. These include filtering blood and excreting metabolic waste into urine. Two proteins, polycystin-1 and polycystin-2, interact in renal tubules and promote the normal development and function of the kidneys. However, the proteins' actions are not well understood. Polycystin-1 and Polycystin-2 are encoded by the PKD1 gene and the PKD2 gene respectively. A mutation in either of these genes can lead to Autosomal Dominant Polycystic Kidney Disease (ADPKD), a common inherited disease leading to progressive renal failure. Several extrarenal manifestations occur as a result of ADPKD including hepatic cysts and intracranial aneurysms. Ultimately, ADPKD often leads to end-stage renal disease that requires dialysis or transplantation. Currently, there is no cure for ADPKD due to setbacks regarding structural determination of the Polycystic Kidney Disease Proteins. Some setbacks are the inability to view the regulatory cytosolic domains of the PKD1/PKD2 channel in atomic detail and understand the function(s) of the polycystic kidney disease proteins. My project examines the ability of Fabs and nanobodies to bind to the PKD2 channel and the PKD1/2 complex as this potentially facilitates structural determination. This is done by stabilizing cytosolic domains and/or promoting a more uniform orientation distribution of these proteins essential for imaging by cryo-electron microscopy.
Faculty Advisor: Cao, Erhu (University of Utah, School of Medicine)
The kidneys are responsible for several essential bodily functions critical to our survival. These include filtering blood and excreting metabolic waste into urine. Two proteins, polycystin-1 and polycystin-2, interact in renal tubules and promote the normal development and function of the kidneys. However, the proteins' actions are not well understood. Polycystin-1 and Polycystin-2 are encoded by the PKD1 gene and the PKD2 gene respectively. A mutation in either of these genes can lead to Autosomal Dominant Polycystic Kidney Disease (ADPKD), a common inherited disease leading to progressive renal failure. Several extrarenal manifestations occur as a result of ADPKD including hepatic cysts and intracranial aneurysms. Ultimately, ADPKD often leads to end-stage renal disease that requires dialysis or transplantation. Currently, there is no cure for ADPKD due to setbacks regarding structural determination of the Polycystic Kidney Disease Proteins. Some setbacks are the inability to view the regulatory cytosolic domains of the PKD1/PKD2 channel in atomic detail and understand the function(s) of the polycystic kidney disease proteins. My project examines the ability of Fabs and nanobodies to bind to the PKD2 channel and the PKD1/2 complex as this potentially facilitates structural determination. This is done by stabilizing cytosolic domains and/or promoting a more uniform orientation distribution of these proteins essential for imaging by cryo-electron microscopy.
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New Graduate Nurses Perceptions of their Preparedness to Practice after Completion of Nurse Residency Programs
Perriton, Kiersten; Eppley, Sydnie; Young, Colleen (Utah Valley University)
Faculty Advisor: Jensen, Francine (Utah Valley University, Nursing)
Purpose: To determine the preparedness of new graduate nurses to practice after completion of nurse residency programs.
Background: New graduate nurses often feel anxious, concerned or ill prepared to practice as nurses on their own. New graduate nurses worry if the residency program has prepared them for their first nursing job sufficiently for them to gain enough confidence and skill to be on their own. Studies on nurse residency programs show that nurses who complete one-year nurse residency programs had remarkable increases in communicating with family, patients and team members, confidence in skills, and ability to prioritize and organize work. There is a need for continued education, such as nurse residency programs and an active interest in new graduate nurses, such as involved mentors or preceptors to help strengthen clinical reasoning and preparedness of new graduate nurses. Stress in new graduate nurses can impede patient safety and can result in the new nurse quitting the position. When new graduates have designated mentors, fit well with unit socialization, and are oriented to multiple areas, it has been identified that it can build their confidence levels and improve retention rates of new graduate nurses. Nurse residency programs need to provide high quality orientation to help them master their careers.
Significance: This research can give insight into whether the implementation of nurse residency programs helps new nurses feel ready to practice on their own. This information may help provide increased safety and quality of care to patients due to new graduate nurses feeling competent and confident to carry out the patient's health care plan. This can help healthcare companies determine if current programs are effective and what needs to be changed. New nurse graduates may gain confidence, practice with increased patient safety, and corporations may retain the new nurses they have just trained.
Faculty Advisor: Jensen, Francine (Utah Valley University, Nursing)
Purpose: To determine the preparedness of new graduate nurses to practice after completion of nurse residency programs.
Background: New graduate nurses often feel anxious, concerned or ill prepared to practice as nurses on their own. New graduate nurses worry if the residency program has prepared them for their first nursing job sufficiently for them to gain enough confidence and skill to be on their own. Studies on nurse residency programs show that nurses who complete one-year nurse residency programs had remarkable increases in communicating with family, patients and team members, confidence in skills, and ability to prioritize and organize work. There is a need for continued education, such as nurse residency programs and an active interest in new graduate nurses, such as involved mentors or preceptors to help strengthen clinical reasoning and preparedness of new graduate nurses. Stress in new graduate nurses can impede patient safety and can result in the new nurse quitting the position. When new graduates have designated mentors, fit well with unit socialization, and are oriented to multiple areas, it has been identified that it can build their confidence levels and improve retention rates of new graduate nurses. Nurse residency programs need to provide high quality orientation to help them master their careers.
Significance: This research can give insight into whether the implementation of nurse residency programs helps new nurses feel ready to practice on their own. This information may help provide increased safety and quality of care to patients due to new graduate nurses feeling competent and confident to carry out the patient's health care plan. This can help healthcare companies determine if current programs are effective and what needs to be changed. New nurse graduates may gain confidence, practice with increased patient safety, and corporations may retain the new nurses they have just trained.
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The Multidimensionality of Infant Prosocial Behavior: An Investigation of Type, Target, and Emergence
Peter J. Reschke, Laura M. Padilla-Walker, Laura A. Stockdale, Chicago Kylin Cox, Hailey Holmgren, Jeffrey L. Hurst, Kjersti Summers, Sarah M. Coyne, Gyuyi Kang (Brigham Young University)
Faculty Advisor: Reschke, Peter (Family, Home, and Social Science; Family Life)
After the first birthday, infants begin to help and share (Dunfield, 2014). However, there is little known about infants' selectivity in helping and sharing and whether these behaviors emerge due to socialization influence or natural tendencies. In this study, 230 infants (109 female, Mage= 1.47 years, SD =.27. Range = .95 years to 2.19 years) were randomly assigned to one of two conditions: (1) Instrumental helping (caregiver) and sharing (experimenter) or (2) instrumental helping (experimenter) and sharing (caregiver). Infants observed a target person (caregiver or experimenter) demonstrate a need (dropped pen = instrumental need; lack of sticker = material desire). Infants were given 60 seconds to respond and their prosocial behaviors (e.g. returning the pen, sharing stickers) were coded using a 5-point scale (see Vaish et al., 2009). Infants engaged in significantly more instrumental helping behaviors (M = 3.37) than sharing behaviors (M = 2.23) t(144) = 7.85, p < .001, 95% CI [0.85, 1.42], d = .87. Infants were also significantly more prosocial toward caregivers (M = 3 .22) than strangers (M = 2 .38). Infants helped the caregiver (M = 4.09) significantly more than the stranger (M = 2.65), t(310) = 7.49, p <.001, 95% CI [1.06, 1.81], d = 1.17. However, infants' sharing towards the caregiver (M = 2.35) and stranger (M = 2.11) did not differ, p =.32, 95% CI [-0.23, 0.71], d = .16. These results suggest that infants are selective in their helping behaviors but not their sharing behaviors in the second year of life. A multidimensional framework of prosocial development will be discussed.
Faculty Advisor: Reschke, Peter (Family, Home, and Social Science; Family Life)
After the first birthday, infants begin to help and share (Dunfield, 2014). However, there is little known about infants' selectivity in helping and sharing and whether these behaviors emerge due to socialization influence or natural tendencies. In this study, 230 infants (109 female, Mage= 1.47 years, SD =.27. Range = .95 years to 2.19 years) were randomly assigned to one of two conditions: (1) Instrumental helping (caregiver) and sharing (experimenter) or (2) instrumental helping (experimenter) and sharing (caregiver). Infants observed a target person (caregiver or experimenter) demonstrate a need (dropped pen = instrumental need; lack of sticker = material desire). Infants were given 60 seconds to respond and their prosocial behaviors (e.g. returning the pen, sharing stickers) were coded using a 5-point scale (see Vaish et al., 2009). Infants engaged in significantly more instrumental helping behaviors (M = 3.37) than sharing behaviors (M = 2.23) t(144) = 7.85, p < .001, 95% CI [0.85, 1.42], d = .87. Infants were also significantly more prosocial toward caregivers (M = 3 .22) than strangers (M = 2 .38). Infants helped the caregiver (M = 4.09) significantly more than the stranger (M = 2.65), t(310) = 7.49, p <.001, 95% CI [1.06, 1.81], d = 1.17. However, infants' sharing towards the caregiver (M = 2.35) and stranger (M = 2.11) did not differ, p =.32, 95% CI [-0.23, 0.71], d = .16. These results suggest that infants are selective in their helping behaviors but not their sharing behaviors in the second year of life. A multidimensional framework of prosocial development will be discussed.
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Addressing Refugee Health Disparities and Outcomes through Community-Based Participatory Research: Toward the Development of a Refugee-Led Community Health Board
Hyman, Rachel; Light, Tim; Montague, Angela; Lucero, Jessica (Utah State University)
Faculty Advisor: Lucero, Jessica (College of Humanities and Social Sciences; Sociology, Social Work and Anthropology Department)
Refugees are recognized as having unique and complex health needs which demand attention upon arrival and throughout the resettlement process (Agrawal & Venkatesh, 2016). Refugee populations are particularly vulnerable to health disparities due to push factors influencing forced migration (Tempany, 2009). These factors include exposure to political violence, natural disasters, and other forms of anthropogenic conflict (UNHCR, 2014). Refugees may arrive in the host country with undiagnosed and untreated health issues, such as infectious diseases, mental distress due to prior traumas, undiagnosed chronic illness, and nutritional deficiencies (Deen & Bridges, 2011). Refugee populations represent high rates of mental and physical health problems compared with the host population (Kirmayer, Gomez-Carrillo, & Veissi�re, 2017). Additional dynamics compound health disparities facing refugees. These include: language barriers, unfamiliarity with a complex health care system, limited health literacy, and inadequate alignment of medical treatments with religious and cultural beliefs (Bowen, 2001; Brown, Carroll, Fogarty, & Holt, 2010). Though there is robust scholarship in the literature and analysis of prevalent health disparities and needs of refugees post-resettlement, few studies address the specific health care concerns of refugees resettled in northern Utah. This study seeks to expand previous findings related to the most salient health care issues facing the refugee community and develop community response to address health disparity. A secondary aim of the research is to determine best practices for the provision of appropriate and effective health services.
Faculty Advisor: Lucero, Jessica (College of Humanities and Social Sciences; Sociology, Social Work and Anthropology Department)
Refugees are recognized as having unique and complex health needs which demand attention upon arrival and throughout the resettlement process (Agrawal & Venkatesh, 2016). Refugee populations are particularly vulnerable to health disparities due to push factors influencing forced migration (Tempany, 2009). These factors include exposure to political violence, natural disasters, and other forms of anthropogenic conflict (UNHCR, 2014). Refugees may arrive in the host country with undiagnosed and untreated health issues, such as infectious diseases, mental distress due to prior traumas, undiagnosed chronic illness, and nutritional deficiencies (Deen & Bridges, 2011). Refugee populations represent high rates of mental and physical health problems compared with the host population (Kirmayer, Gomez-Carrillo, & Veissi�re, 2017). Additional dynamics compound health disparities facing refugees. These include: language barriers, unfamiliarity with a complex health care system, limited health literacy, and inadequate alignment of medical treatments with religious and cultural beliefs (Bowen, 2001; Brown, Carroll, Fogarty, & Holt, 2010). Though there is robust scholarship in the literature and analysis of prevalent health disparities and needs of refugees post-resettlement, few studies address the specific health care concerns of refugees resettled in northern Utah. This study seeks to expand previous findings related to the most salient health care issues facing the refugee community and develop community response to address health disparity. A secondary aim of the research is to determine best practices for the provision of appropriate and effective health services.
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Adolescent Patients seen for Sexual Assault Forensic Examination: Using Data to inform practice
Miles, Leslie; Valentine, Julie (Brigham Young University)
Faculty Advisor: Miles, Leslie (Brigham Young University, College of Nursing); Valentine, Julie (Brigham Young University, College of Nursing)
1 in 10 adolescents (13-18 years old) reported sexual violence in the dating environment with a prevalence rate of 14% among girls and 8% among boys (Wincentak et al., 2017). Additionally, Arliksson-Schmidt et al. (2010) found that adolescent girls with a physical disability or long-term health problem were more likely to experience sexual violence (p=.003). The current literature is limited on describing the characteristics and vulnerabilities of adolescent sexual assault patients. Researchers have found multiple negative sequelae in adolescents who have been sexually assaulted, which includes the following; major depressive disorder, suicide risk, agoraphobia, alcohol abuse & dependence, and substance abuse & dependence (Walt et al., 2014).
To better understand adolescent patients and to guide nursing care, a large (n=5,600) retrospective chart review of SAFEs documentation (2010-2018) examines adolescent descriptors (age 14-18) in a Western state in the United States. Variables include gender, race, age, relationship to suspect, online meeting, pre-existing medical conditions, pre-existing mental illness, previous history of sexual assault, number of non-anogenital injuries, number of anogenital injuries, alcohol and drug use, multiple suspects, and suspect actions (violent physical acts). Comparisons to patients over the age of 18 years will be provided.
The purpose of this podium presentation is to review research findings concerning the demographics and characteristics of adolescents seen for sexual assault forensic examinations to better inform health care professionals. Discussion will include possible medical and nursing interventions to mitigate the potential harmful effects of adolescent sexual assault.
Faculty Advisor: Miles, Leslie (Brigham Young University, College of Nursing); Valentine, Julie (Brigham Young University, College of Nursing)
1 in 10 adolescents (13-18 years old) reported sexual violence in the dating environment with a prevalence rate of 14% among girls and 8% among boys (Wincentak et al., 2017). Additionally, Arliksson-Schmidt et al. (2010) found that adolescent girls with a physical disability or long-term health problem were more likely to experience sexual violence (p=.003). The current literature is limited on describing the characteristics and vulnerabilities of adolescent sexual assault patients. Researchers have found multiple negative sequelae in adolescents who have been sexually assaulted, which includes the following; major depressive disorder, suicide risk, agoraphobia, alcohol abuse & dependence, and substance abuse & dependence (Walt et al., 2014).
To better understand adolescent patients and to guide nursing care, a large (n=5,600) retrospective chart review of SAFEs documentation (2010-2018) examines adolescent descriptors (age 14-18) in a Western state in the United States. Variables include gender, race, age, relationship to suspect, online meeting, pre-existing medical conditions, pre-existing mental illness, previous history of sexual assault, number of non-anogenital injuries, number of anogenital injuries, alcohol and drug use, multiple suspects, and suspect actions (violent physical acts). Comparisons to patients over the age of 18 years will be provided.
The purpose of this podium presentation is to review research findings concerning the demographics and characteristics of adolescents seen for sexual assault forensic examinations to better inform health care professionals. Discussion will include possible medical and nursing interventions to mitigate the potential harmful effects of adolescent sexual assault.
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Variations in Paint on San Juan Painted Red Ware
Greaves, Aspen ; Allison, Jim (Brigham Young University)
Faculty Advisor: Allison, Jim (Family, Home, and Social Sciences; Anthropology)
Portable x-ray fluorescence (PXRF) analysis is a quantitative measure of the presence of an element. Elements from painted red ware sherds from the San Juan region were measured on painted and non-painted portions of the sherds, demonstrating the presence of elements in the paint as opposed to the paste. In particular, manganese, lead, and copper, along with a more ubiquitous iron, were found in the paint. The presences of manganese indicates the intention for the paint to be black when fired, a useful tool in identifying sherds. At Site 13 (42sa13) for example, which was burned, the sherds can appear to be Abajo red-on-orange when they may better be described as Bluff black-on-red. Lead and copper are a bit less straight-forward. Lead appears rarely, and may have no purpose, or could be an intentional sourcing choice. Another question comes from the presence of copper, which may have created a turquoise paint pre- firing. Turquoise is an important color in Pueblo color theory, and so if copper does create a turquoise paint, the presence of copper may be deliberate. Variation in paint, particularly crossed with neutron activation data, leads to a firmer understanding of decisions inherent in the ceramic creation process.
Faculty Advisor: Allison, Jim (Family, Home, and Social Sciences; Anthropology)
Portable x-ray fluorescence (PXRF) analysis is a quantitative measure of the presence of an element. Elements from painted red ware sherds from the San Juan region were measured on painted and non-painted portions of the sherds, demonstrating the presence of elements in the paint as opposed to the paste. In particular, manganese, lead, and copper, along with a more ubiquitous iron, were found in the paint. The presences of manganese indicates the intention for the paint to be black when fired, a useful tool in identifying sherds. At Site 13 (42sa13) for example, which was burned, the sherds can appear to be Abajo red-on-orange when they may better be described as Bluff black-on-red. Lead and copper are a bit less straight-forward. Lead appears rarely, and may have no purpose, or could be an intentional sourcing choice. Another question comes from the presence of copper, which may have created a turquoise paint pre- firing. Turquoise is an important color in Pueblo color theory, and so if copper does create a turquoise paint, the presence of copper may be deliberate. Variation in paint, particularly crossed with neutron activation data, leads to a firmer understanding of decisions inherent in the ceramic creation process.
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Younger Service Members and Veterans at Higher Risk of Coercive Sexual Assault
Christensen, Kate L.; Hinkson Jr, Kent D.; Brooks Malisa M.; Bryan, Craig J.� (Utah Valley University)
Faculty Advisor: Hinkson Jr, Kent (Utah Valley University and University of Utah, Psychology); Brooks, Malisa (University of Utah, Psychology)
Among the staggering rates of sexual assault, little attention has been directed towards the specific risk factors involved with coercive sexual assault. The few studies that have been conducted focus solely on college campuses. Studies have found that the potential risk factors between forced sexual assault and coercive sexual assault are fundamentally different. While forced sexual assault is associated with environmental risk factors such as alcohol, coercive assault risk factors have a stronger relationship with the victim's level of depression and self-esteem. Though depression and low self-esteem can affect people for a variety of different reasons, age tends to be a reliable predictor of both of these risk factors. Depression and low self-esteem have some of the highest rates among teens and young adults. When focusing on the Military, we see depression rates higher than that of the general public, with similar patterns of teenagers and young adults (18 to 25) being the most affected. With the knowledge that depression and low self-esteem are risk factors in coercive sexual assault and knowing an age group that is more likely to be depressed and struggle with esteem, we should expect to see a relationship between age and being a victim of coercive sexual assault. In a survey consisting of veterans, age had a mild relationship with coercive rape, with younger people being more susceptible and their older counterparts holding less risk. When focusing on other distinctions of sexual crimes such as harassment, assault, and rape, age was not found to be a risk factor. Knowledge of the relationship between coercive sexual assault and age carries important implications, particularly in the form of education and support. Leaders armed with this data can inform young people of this potential risk, provide preventative strategies, and recommend therapy or support groups when necessary.
Faculty Advisor: Hinkson Jr, Kent (Utah Valley University and University of Utah, Psychology); Brooks, Malisa (University of Utah, Psychology)
Among the staggering rates of sexual assault, little attention has been directed towards the specific risk factors involved with coercive sexual assault. The few studies that have been conducted focus solely on college campuses. Studies have found that the potential risk factors between forced sexual assault and coercive sexual assault are fundamentally different. While forced sexual assault is associated with environmental risk factors such as alcohol, coercive assault risk factors have a stronger relationship with the victim's level of depression and self-esteem. Though depression and low self-esteem can affect people for a variety of different reasons, age tends to be a reliable predictor of both of these risk factors. Depression and low self-esteem have some of the highest rates among teens and young adults. When focusing on the Military, we see depression rates higher than that of the general public, with similar patterns of teenagers and young adults (18 to 25) being the most affected. With the knowledge that depression and low self-esteem are risk factors in coercive sexual assault and knowing an age group that is more likely to be depressed and struggle with esteem, we should expect to see a relationship between age and being a victim of coercive sexual assault. In a survey consisting of veterans, age had a mild relationship with coercive rape, with younger people being more susceptible and their older counterparts holding less risk. When focusing on other distinctions of sexual crimes such as harassment, assault, and rape, age was not found to be a risk factor. Knowledge of the relationship between coercive sexual assault and age carries important implications, particularly in the form of education and support. Leaders armed with this data can inform young people of this potential risk, provide preventative strategies, and recommend therapy or support groups when necessary.
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The Relationships Between Emotional Regulation and PTSD Criterion D
Davis, Justin; Hinkson, Kent; Brooks, Malisa; Bryan, Craig (University of Utah)
Faculty Advisor: Hinkson, Kent (University of Utah, College of Social and Behavioral Sciences)
Emotion Regulation is broadly defined as a person's ability to modulate or maintain emotional states in order to achieve a goal. Evidence is mounting that among veterans, emotional regulation is a critical and core component directly related to veterans' abilities to work through clinical protocols for PTSD and suicidality, transition to civilian populations, reintegrate with families, and to experience overall well-being. Several academic, research, and governmental organizations have undertaken the tasks associated with understanding causal and correlative factors associated veteran suicide, and in the milieu this endeavor has shed light on suicidal phenomena more broadly applicable to general populations. As such, clinicians, researchers, and the general public have a stake in understanding emotion regulation in ways that inform development of normative mental health and various etiologies and courses of psychopathology. More specifically, among student veterans with PTSD, emotional dysregulation has been associated with greater psychological distress and higher rates of health-risk behaviors such as binge-drinking, drinking and driving, and physical aggression. Current research shows a moderate inverse relationship between the experience and expression of joy and Criterion D (negative alterations in cognitions and mood) of PTSD such that positive affective experiences may be suppressed or attenuated in those student veterans who endorse moderate to severe symptoms. This emotional reticence, whether personal or public, is likely to reinforce avoidant behavioral schemas, contributing to and maintaining the emotional dysregulation sequelae of PTSD well after military service and into the future across many contexts. The main aim of this study was to better understand and conceptualize the relationship between negative alterations in cognition and mood and emotion regulation among trauma-exposed veterans. This understanding will help support future research, screening, and prevention programs for PTSD and suicide along with conceptualization and application of emotion regulation intervention protocols in clinical veteran populations.
Faculty Advisor: Hinkson, Kent (University of Utah, College of Social and Behavioral Sciences)
Emotion Regulation is broadly defined as a person's ability to modulate or maintain emotional states in order to achieve a goal. Evidence is mounting that among veterans, emotional regulation is a critical and core component directly related to veterans' abilities to work through clinical protocols for PTSD and suicidality, transition to civilian populations, reintegrate with families, and to experience overall well-being. Several academic, research, and governmental organizations have undertaken the tasks associated with understanding causal and correlative factors associated veteran suicide, and in the milieu this endeavor has shed light on suicidal phenomena more broadly applicable to general populations. As such, clinicians, researchers, and the general public have a stake in understanding emotion regulation in ways that inform development of normative mental health and various etiologies and courses of psychopathology. More specifically, among student veterans with PTSD, emotional dysregulation has been associated with greater psychological distress and higher rates of health-risk behaviors such as binge-drinking, drinking and driving, and physical aggression. Current research shows a moderate inverse relationship between the experience and expression of joy and Criterion D (negative alterations in cognitions and mood) of PTSD such that positive affective experiences may be suppressed or attenuated in those student veterans who endorse moderate to severe symptoms. This emotional reticence, whether personal or public, is likely to reinforce avoidant behavioral schemas, contributing to and maintaining the emotional dysregulation sequelae of PTSD well after military service and into the future across many contexts. The main aim of this study was to better understand and conceptualize the relationship between negative alterations in cognition and mood and emotion regulation among trauma-exposed veterans. This understanding will help support future research, screening, and prevention programs for PTSD and suicide along with conceptualization and application of emotion regulation intervention protocols in clinical veteran populations.
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Voluntary or Not, Still No Equilibrium Play in the Ultimatum Game: A Failed Replication
Brooksby, Austin; Meyer, Jake; Rentschler, Lucas; Spofford, Robbie (Utah State University)
Faculty Advisor: Rentschler, Lucas (Jon M. Huntsman School of Business, Economics and Finance Department)
The ultimatum game is a common experimental economics game done in pairs in which one person chooses a way of dividing a sum of money, and then proposes that split as an ultimatum to the other: Either accept it, or we both walk away with nothing. In theory, equilibrium play would indicate everyone should accept any split they're offered-regardless of the equity-but the experimental economics literature robustly rejects that theory. Smith and Wilson's 2017 paper "Equilibrium Play in Voluntary Ultimatum Games: Beneficence Cannot Be Extorted" produced results different from the vast literature, by making game participation voluntary within the lab. We attempted to replicate Smith and Wilson's results, but failed to do so. The most notable difference between our experiments was our subject pool, so we ran additional trials of the standard ultimatum game and confirmed our subject pool was not significantly different than the general literature. Our paper provides a great example of the importance of replicating results in the social sciences, in addition to a specific contribution to the ultimatum game literature.
Faculty Advisor: Rentschler, Lucas (Jon M. Huntsman School of Business, Economics and Finance Department)
The ultimatum game is a common experimental economics game done in pairs in which one person chooses a way of dividing a sum of money, and then proposes that split as an ultimatum to the other: Either accept it, or we both walk away with nothing. In theory, equilibrium play would indicate everyone should accept any split they're offered-regardless of the equity-but the experimental economics literature robustly rejects that theory. Smith and Wilson's 2017 paper "Equilibrium Play in Voluntary Ultimatum Games: Beneficence Cannot Be Extorted" produced results different from the vast literature, by making game participation voluntary within the lab. We attempted to replicate Smith and Wilson's results, but failed to do so. The most notable difference between our experiments was our subject pool, so we ran additional trials of the standard ultimatum game and confirmed our subject pool was not significantly different than the general literature. Our paper provides a great example of the importance of replicating results in the social sciences, in addition to a specific contribution to the ultimatum game literature.
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Wituk and Manduru: The Transformative and Redemptive Power of Quichua Women in Ecuador
Maw, Madison (Brigham Young University)
Faculty Advisor: Nuckols, Janis (Brigham Young University, Linguistics); Thompson, Gregory (Brigham Young University, Anthropology)
In Ecuadorian Quichua culture people do what they can do to avoid being described as quilla—a behavior encapsulating both laziness and sexual promiscuity. Many of their myths revolve an individual who encapsulates one or both parts of quilla, the tale of Wituk and Manduru included. These behaviors are ones that estrange an individual from their family ties, which is a keystone motor of Quichua society. These myths, being origin stories, always end up with the person transforming into a part of nature, usually an animal or plant.
Wituk and Manduru's tale is one of the longer myths as well as one of the only that demonstrates both aspects of quilla so clearly. However, while it depicts what is considered the worst traits, it also demonstrates how to redeem oneself. At the end of the story the sisters transform themselves into trees that produce pods that when mashed create red or black paint. The girls use this to paint the men who they interacted with in their journey into more productive animals.
This paper will explore the implications this story has in modern life for the Quichua people, women in particular. The paint of these trees is highly important in all realms over which women preside, including pottery, beauty, and maintaining the chagra (in simplistic terms, a garden). The paint is used in a transformative and representative way, making the ritual plant grow stronger and allowing women to harness the power of animals around them, just to name a few. Women are able to use this plant to transform themselves and those around them in order to make a better society overall.
Faculty Advisor: Nuckols, Janis (Brigham Young University, Linguistics); Thompson, Gregory (Brigham Young University, Anthropology)
In Ecuadorian Quichua culture people do what they can do to avoid being described as quilla—a behavior encapsulating both laziness and sexual promiscuity. Many of their myths revolve an individual who encapsulates one or both parts of quilla, the tale of Wituk and Manduru included. These behaviors are ones that estrange an individual from their family ties, which is a keystone motor of Quichua society. These myths, being origin stories, always end up with the person transforming into a part of nature, usually an animal or plant.
Wituk and Manduru's tale is one of the longer myths as well as one of the only that demonstrates both aspects of quilla so clearly. However, while it depicts what is considered the worst traits, it also demonstrates how to redeem oneself. At the end of the story the sisters transform themselves into trees that produce pods that when mashed create red or black paint. The girls use this to paint the men who they interacted with in their journey into more productive animals.
This paper will explore the implications this story has in modern life for the Quichua people, women in particular. The paint of these trees is highly important in all realms over which women preside, including pottery, beauty, and maintaining the chagra (in simplistic terms, a garden). The paint is used in a transformative and representative way, making the ritual plant grow stronger and allowing women to harness the power of animals around them, just to name a few. Women are able to use this plant to transform themselves and those around them in order to make a better society overall.
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True Prophylactic Treatment effect in a Rat PTSD Model on Synaptic Plasticity in Ventral Hippocampal and Lateral Amygdala
Miller, Roxanne; Winzenried, Eric; Everett, Anna; Edwards, Jeffrey (Brigham Young University)
Faculty Advisor: Edwards, Jeffrey (Life Sciences, Physiology and Developmental Biology)
Post-traumatic stress disorder (PTSD) is a complex anxiety/depression disorder that affects about 1 out of 4 individuals after a stressful/traumatic experience. One common model to induce PTSD is social defeat (SD) combined with chronic light exposure in rats. First, more naturally anxious rats were selected based on results of an open field test where cat fur and fox urine were placed in one quadrant. Rats were classified as anxious if they avoided that quadrant, froze for long periods of time, did not rear, and frequently urinated or defecated. The naturally anxious rats were used in the SD protocol. Next, the elevated plus maze (EPM) and light-dark transition (LDT) tests were used to detect anxious behavior at the conclusion of SD. The SD protocol caused significant anxious behavior when compared to controls. Next, we performed LTP field electrophysiology experiments in brain slices of ventral hippocampus and basolateral amygdala, regions known to have altered plasticity in PTSD. SD caused a significant increase in long-term potentiation (LTP) in the ventral hippocampus and basolateral amygdala. To determine whether a prophylactic treatment could prevent the physiological changes of PTSD, propranolol and mifepristone were simultaneously administered at 10 mg/kg doses by intraperitoneal (IP) injection one week prior and during the entire duration of SD. These drugs significantly decreased LTP in the VH and BLA back to near-control levels while SD rats with vehicle injections still had elevated LTP.
Faculty Advisor: Edwards, Jeffrey (Life Sciences, Physiology and Developmental Biology)
Post-traumatic stress disorder (PTSD) is a complex anxiety/depression disorder that affects about 1 out of 4 individuals after a stressful/traumatic experience. One common model to induce PTSD is social defeat (SD) combined with chronic light exposure in rats. First, more naturally anxious rats were selected based on results of an open field test where cat fur and fox urine were placed in one quadrant. Rats were classified as anxious if they avoided that quadrant, froze for long periods of time, did not rear, and frequently urinated or defecated. The naturally anxious rats were used in the SD protocol. Next, the elevated plus maze (EPM) and light-dark transition (LDT) tests were used to detect anxious behavior at the conclusion of SD. The SD protocol caused significant anxious behavior when compared to controls. Next, we performed LTP field electrophysiology experiments in brain slices of ventral hippocampus and basolateral amygdala, regions known to have altered plasticity in PTSD. SD caused a significant increase in long-term potentiation (LTP) in the ventral hippocampus and basolateral amygdala. To determine whether a prophylactic treatment could prevent the physiological changes of PTSD, propranolol and mifepristone were simultaneously administered at 10 mg/kg doses by intraperitoneal (IP) injection one week prior and during the entire duration of SD. These drugs significantly decreased LTP in the VH and BLA back to near-control levels while SD rats with vehicle injections still had elevated LTP.
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A Comparative Study of Women's Satisfaction During their Labor and Delivery Experience Between a Midwife and an Obstetrician/Gynecologists
Salas, Norma; Condie, Kali; Cook, Lauralee (Utah Valley University)
Faculty Advisor: Jensen, Francine (Utah Valley University, Nursing)
Problem Statement:
Depending on the provider a woman has during her delivery, the education, interventions, and care she receives will differ. Variations of care under an obstetrician and gynecologist (OB/GYN) compared to a midwife may produce differing satisfactory results for women experiencing labor and delivery.
Purpose:
The purpose of this research study is to discover if women who have delivered with both an obstetrician/gynecologist and a midwife are more satisfied with their birthing experience under the care of one provider compared to the other.
Research Question:
Are women who have experienced labor and delivery with an OB/GYN and a midwife more satisfied with their birthing experiences from one provider compared to the other?
Background:
In a patient-centered world, it should be up to the provider and expecting mother to choose the modality of delivery they would like, including the place, medical interventions, positioning, and methods of delivery. OB/GYNs and Midwives vary in practices, and implementations during gestation and delivery. Dissatisfaction with labor and delivery is an aspect of the current healthcare industry that needs to be addressed in order to improve patient care. Coxon, Sandall, and Fulop highlight this issue by pointing out that many women feel constrained with their decisions regarding labor and delivery and that delivery opportunities may be limited due to influences from cultural and historical associations as practiced by the provider (2014). Patient satisfaction is also influenced by pressures women in labor and delivery experience in order to accommodate their providers wishes.
Hope to accomplish:
We hope to determine if women's satisfaction during their labor and delivery experiences are higher with either a midwife or an obstetrician/gynecologist, as well as to promote better education and patient autonomy to increase patient experience satisfaction.
Faculty Advisor: Jensen, Francine (Utah Valley University, Nursing)
Problem Statement:
Depending on the provider a woman has during her delivery, the education, interventions, and care she receives will differ. Variations of care under an obstetrician and gynecologist (OB/GYN) compared to a midwife may produce differing satisfactory results for women experiencing labor and delivery.
Purpose:
The purpose of this research study is to discover if women who have delivered with both an obstetrician/gynecologist and a midwife are more satisfied with their birthing experience under the care of one provider compared to the other.
Research Question:
Are women who have experienced labor and delivery with an OB/GYN and a midwife more satisfied with their birthing experiences from one provider compared to the other?
Background:
In a patient-centered world, it should be up to the provider and expecting mother to choose the modality of delivery they would like, including the place, medical interventions, positioning, and methods of delivery. OB/GYNs and Midwives vary in practices, and implementations during gestation and delivery. Dissatisfaction with labor and delivery is an aspect of the current healthcare industry that needs to be addressed in order to improve patient care. Coxon, Sandall, and Fulop highlight this issue by pointing out that many women feel constrained with their decisions regarding labor and delivery and that delivery opportunities may be limited due to influences from cultural and historical associations as practiced by the provider (2014). Patient satisfaction is also influenced by pressures women in labor and delivery experience in order to accommodate their providers wishes.
Hope to accomplish:
We hope to determine if women's satisfaction during their labor and delivery experiences are higher with either a midwife or an obstetrician/gynecologist, as well as to promote better education and patient autonomy to increase patient experience satisfaction.
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Aging-associated accumulation of myocardial protein aggregates in mice is attenuated by late-in-life exercise training.
Symons, J. David; Thompson, Lauren; Ramous, Caroline; Cho, JaeMin; Boudina, Sihem; Margetts, Alex; Buzianis, Skye; Park, Seul Ki; Luu, Kiana; Hansen, Michele; Pires, Karla; Whitehead, Kevin; Carter, Kandis; Buffolo, Marcio (University of Utah)
Faculty Advisor: Symones, J. David (University of Utah, Nutrition and Integrative Physiology)
Protein aggregates accumulate and organelles become damaged and / or dysfunctional during the process of healthy aging. A progressive loss of the cellular quality control mechanism autophagy (i.e., "self-eating") contributes to this age-associated decline in cellular function in many organs. Evidence for an age-associated repression in cardiac autophagy is not consistent. We hypothesized that 24-month old (old) male C57Bl6/J mice exhibit repressed autophagosome formation in the heart, an accumulation of cardiac protein aggregates, myocardial dysfunction, and reduced exercise capacity vs. 6-month old (adult) mice. First, cardiac lysates from old mice displayed reduced (p<0.05) accumulation of LC3II / GAPDH and degradation of p62 vs. adult animals (assessed via immunoblotting; n=12 per group). Second, the lysosomal acidification inhibitor chloroquine (CQ) induced accrual (p<0.05) of LC3II / GAPDH and p62 in hearts from adult but not old mice (quantified by immunoblotting; n=7 per group). Third, the number and size of protein aggregates was higher (p<0.05) in hearts from old vs. adult mice (measured via scanning electron microscopy; n=5 per group). Fourth, left ventricular mass / tibial length was greater (p<0.05), and indices of systolic, diastolic, and global left ventricular function (measured via transthoracic echocardiography) were impaired (p<0.05), in old vs. adult animals (n=12 per group). Finally, maximal workload performed during a treadmill-test, and soleus muscle oxidative enzyme capacity (citrate synthase activity assessed via ELISA), were less (p<0.05) in aged (n=11) vs. adult (n=12) mice. To determine whether late-in-life exercise training improves cardiac autophagy to an extent that demonstrates functional relevance, separate cohorts of older male mice completed a progressive-resistance treadmill-running program (old-ETR) or remained sedentary (old-SED) from 21-24 months. Body composition (estimated via nuclear magnetic resonance), exercise performance during a maximal workload test, soleus muscle citrate synthase activity, indices of cardiac antioxidant enzyme activity (quantified via immunoblotting), markers of cardiac autophagy, accumulation of cardiac protein aggregates, and indices of myocardial function, all improved (p<0.05) in old-ETR (n=11) vs. old-SED (n=12) mice. These data are the first to demonstrate that markers of cardiac autophagy are elevated, and indicators of protein aggregate removal and myocardial function are improved, in older mice that complete a treadmill-training regimen that is sufficient to increase skeletal muscle CS activity and maximal exercise capacity. Our results provide strong proof of concept to evaluate cause and effect relationships among exercise-training, myocardial autophagy, and cardiac function using genetic approaches in pre-clinical models and these studies are ongoing in our laboratory.
Faculty Advisor: Symones, J. David (University of Utah, Nutrition and Integrative Physiology)
Protein aggregates accumulate and organelles become damaged and / or dysfunctional during the process of healthy aging. A progressive loss of the cellular quality control mechanism autophagy (i.e., "self-eating") contributes to this age-associated decline in cellular function in many organs. Evidence for an age-associated repression in cardiac autophagy is not consistent. We hypothesized that 24-month old (old) male C57Bl6/J mice exhibit repressed autophagosome formation in the heart, an accumulation of cardiac protein aggregates, myocardial dysfunction, and reduced exercise capacity vs. 6-month old (adult) mice. First, cardiac lysates from old mice displayed reduced (p<0.05) accumulation of LC3II / GAPDH and degradation of p62 vs. adult animals (assessed via immunoblotting; n=12 per group). Second, the lysosomal acidification inhibitor chloroquine (CQ) induced accrual (p<0.05) of LC3II / GAPDH and p62 in hearts from adult but not old mice (quantified by immunoblotting; n=7 per group). Third, the number and size of protein aggregates was higher (p<0.05) in hearts from old vs. adult mice (measured via scanning electron microscopy; n=5 per group). Fourth, left ventricular mass / tibial length was greater (p<0.05), and indices of systolic, diastolic, and global left ventricular function (measured via transthoracic echocardiography) were impaired (p<0.05), in old vs. adult animals (n=12 per group). Finally, maximal workload performed during a treadmill-test, and soleus muscle oxidative enzyme capacity (citrate synthase activity assessed via ELISA), were less (p<0.05) in aged (n=11) vs. adult (n=12) mice. To determine whether late-in-life exercise training improves cardiac autophagy to an extent that demonstrates functional relevance, separate cohorts of older male mice completed a progressive-resistance treadmill-running program (old-ETR) or remained sedentary (old-SED) from 21-24 months. Body composition (estimated via nuclear magnetic resonance), exercise performance during a maximal workload test, soleus muscle citrate synthase activity, indices of cardiac antioxidant enzyme activity (quantified via immunoblotting), markers of cardiac autophagy, accumulation of cardiac protein aggregates, and indices of myocardial function, all improved (p<0.05) in old-ETR (n=11) vs. old-SED (n=12) mice. These data are the first to demonstrate that markers of cardiac autophagy are elevated, and indicators of protein aggregate removal and myocardial function are improved, in older mice that complete a treadmill-training regimen that is sufficient to increase skeletal muscle CS activity and maximal exercise capacity. Our results provide strong proof of concept to evaluate cause and effect relationships among exercise-training, myocardial autophagy, and cardiac function using genetic approaches in pre-clinical models and these studies are ongoing in our laboratory.
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The Influence of Social Media on Impulsive Emotional Responses
Bergman, Kyle (Utah Valley University)
Faculty Advisor: Smith-Johnson, Amber (Utah Valley University, English)
The number of social media users has risen dramatically over the past few years; since 2008, the number of monthly users of social media has risen from 222 million to 2.24 billion. Studies have recently suggested that a correlation exists between this dramatic increase in electronic social behavior and impulsivity. Research suggests that the concept of "Fear of Missing Out" and the desensitizing of exciting behaviors are both possible causes (Baumgartner et al). In addition to the rise in impulsive behaviors, there have been a host of other studies that have shown how social media exposure is affecting the cognitive capacities of developing minds. Among their findings assert that behaviors such as Increased anxiety, depression, narcolepsy, anger, agitation, and internet addiction are increasing at an alarming rate (Bilgin, Tas). I want to take this research further and study how social media usage can cause impulsive views of self-value and worth. To conduct this experiment, I will create a survey designed to measure the impulsive, instinctive responses of college aged students to certain situations that would be commonly found online or actuality. I predict that because social media platforms often contain incomplete information about a post, the questions from the survey that will contribute to either jealousy or lower self-worth will be ones similar to what they would find on these platforms. I hope that these findings will help parents understand the impulsive influences that social media can have on their children.
Faculty Advisor: Smith-Johnson, Amber (Utah Valley University, English)
The number of social media users has risen dramatically over the past few years; since 2008, the number of monthly users of social media has risen from 222 million to 2.24 billion. Studies have recently suggested that a correlation exists between this dramatic increase in electronic social behavior and impulsivity. Research suggests that the concept of "Fear of Missing Out" and the desensitizing of exciting behaviors are both possible causes (Baumgartner et al). In addition to the rise in impulsive behaviors, there have been a host of other studies that have shown how social media exposure is affecting the cognitive capacities of developing minds. Among their findings assert that behaviors such as Increased anxiety, depression, narcolepsy, anger, agitation, and internet addiction are increasing at an alarming rate (Bilgin, Tas). I want to take this research further and study how social media usage can cause impulsive views of self-value and worth. To conduct this experiment, I will create a survey designed to measure the impulsive, instinctive responses of college aged students to certain situations that would be commonly found online or actuality. I predict that because social media platforms often contain incomplete information about a post, the questions from the survey that will contribute to either jealousy or lower self-worth will be ones similar to what they would find on these platforms. I hope that these findings will help parents understand the impulsive influences that social media can have on their children.
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Why Say No, When You Could Say Yes? A survey of the why, the how, and the emotions of sexually abstinent adults.
Hale, Kaysi; Anderson, Chris (Utah Valley University)
Faculty Advisor: Anderson, Chris (Utah Valley University, Psychology)
While there is significant data on adolescent sexual activity, education, and attitudes, there is little research done on adults who choose to stay abstinent, especially in the United States. Religiosity plays a significant role in reducing sexual behaviors before marriage. Many Christian faiths teach that sex should only be engaged in after marriage, so many followers choose to stay abstinent until marriage. Education about sex contributes to individuals choosing to stay abstinent and/or choosing to use safe-sex practices. Gender is not a large factor when considering reasons why individuals choose to stay abstinent; women have slightly lower rates of pre-marital sex at 94%; men at 96%. Sexual health and sexual well-being are difficult to define, but especially challenging when trying to define it for those choosing to stay abstinent into adulthood. The proposed study will sample an anticipated 200 self-reported abstinent undergraduates at Utah Valley University. This university has a high proportion of Christian students who are predominantly members of the Church of Jesus Christ of Latter-Day Saints. Data will be collected about why the students report they are remaining sexually abstinent as well as their sexual attitudes, beliefs, behaviors, and feelings about their own sexuality. Correlations can be drawn between religiosity, gender, age, perceived healthy attitudes towards individual sexuality, feelings about sexual stimulating behavior, among other factors. This paper will contribute to the standing data about religiosity and sexuality. It will enhance the literature about how abstinent adults feel about their own sexuality.
Faculty Advisor: Anderson, Chris (Utah Valley University, Psychology)
While there is significant data on adolescent sexual activity, education, and attitudes, there is little research done on adults who choose to stay abstinent, especially in the United States. Religiosity plays a significant role in reducing sexual behaviors before marriage. Many Christian faiths teach that sex should only be engaged in after marriage, so many followers choose to stay abstinent until marriage. Education about sex contributes to individuals choosing to stay abstinent and/or choosing to use safe-sex practices. Gender is not a large factor when considering reasons why individuals choose to stay abstinent; women have slightly lower rates of pre-marital sex at 94%; men at 96%. Sexual health and sexual well-being are difficult to define, but especially challenging when trying to define it for those choosing to stay abstinent into adulthood. The proposed study will sample an anticipated 200 self-reported abstinent undergraduates at Utah Valley University. This university has a high proportion of Christian students who are predominantly members of the Church of Jesus Christ of Latter-Day Saints. Data will be collected about why the students report they are remaining sexually abstinent as well as their sexual attitudes, beliefs, behaviors, and feelings about their own sexuality. Correlations can be drawn between religiosity, gender, age, perceived healthy attitudes towards individual sexuality, feelings about sexual stimulating behavior, among other factors. This paper will contribute to the standing data about religiosity and sexuality. It will enhance the literature about how abstinent adults feel about their own sexuality.
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