Fine Arts

Authors: Miaja Coombs, Greg Carling. Mentors: Greg Carling. Insitution: Brigham Young University. Our research delves into the intricate relationship between glaciers and Alaskan rivers. We embarked on an extensive study across Southcentral and Interior Alaska, spanning various mountain ranges, to examine how glaciers affect the water chemistry in these regions. From small cirque glaciers to expansive valley glaciers and sediment-covered glaciers, we collected data from river sites extending from glacier termini to the ocean or larger river systems. Over a span of two years, our weekly and monthly samples shed light on the complex interplay of elements, isotopes, and seasonal variations in water sources within these proglacial rivers and streams. Our findings reveal the dynamic nature of glacier-influenced watersheds, especially in the context of a changing climate.

Authors: Carolina Corrales. Mentors: James R. Allison. Insitution: Brigham Young University. This research analyzes ceramics found at the Alkali Ridge Site 13 in southeast Utah. The information generated with this research will allow us to know more about the technological choices of the Early Pueblo I people who lived at this location in the late A.D. 700s. The methodology will examine rim sherds through refiring and porosity tests. Refiring small sections of the sherds will provide initial information about the chemical composition of the clay used to create the vessels. The porosity tests should help determine the pieces' physical properties linked to different technologies. The combination of all these data will show differences in raw materials and their impact on the constitution of the vessels. The database obtained will allow us to statistically compare information from red, grey, and white wares, identifying patterns in size, shape, kind of material, and the technology used for each type.

Authors: Eli F Smith, Christopher Dillon, Matthew S Allen. Mentors: Matt Allen. Insitution: Brigham Young University. Background: Shear wave tensiometry offers a method to measure in vivo tendon tension, crucial for inferring applied loads on tendons. However, existing equipment for this purpose is costly and lacks mobility, limiting the ability to study a larger cohort of subjects engaged in various physical activities. Goal: This research aimed to assess the viability of utilizing low-cost digital accelerometers in conjunction with an Arduino-based microcontroller for shear wave tensiometry. Approach: This work employs surface-mounted accelerometers on a custom flexible printed circuit board (PCB), so that even spacing can be maintained between the accelerometers without interfering in data collection. To test the system and verify its ability to acquire measurements at a high enough rate, the PCB was connected to a shaker driven with a known sinusoidal signal. The flexible PCB was held in place on the Achilles tendon using athletic tape with a tapper placed on the tendon to send a shear wave through the tendon. Results: The results obtained to date compare the accuracy of the proposes system relative to the current system, which uses instrument grade accelerometers. Results obtained to date on the tendon reveal the degree to which the PCB interferes with the measurements, and suggest possible modifications to improve future designs. Conclusion: To attain valid shear wave tensiometry data, further iterations of the flexible PCB design are needed. Moreover, employing more powerful microcontrollers capable of accommodating the requisite sample rates is necessary for an improved system.

Authors: Shauri Thacker. Mentors: Nicole Dib. Insitution: Southern Utah University. The representation of Black narratives within the medium of comics and graphic novels has been and continues to be sparse compared to the focus on white characters and stories. In recent years, however, a new paradigm of Black representation has been appearing in comics and comics studies. Emerging from Black Lives Matter movement discourse about police brutality and taking a new angle on the “organic black protest tradition” is Victor LaValle and Dietrich Smith’s 2017 graphic novel Destroyer. Their visual narrative follows the last descendant of Frankenstein—Dr. Josephine Baker—and her endeavors for justice after the murder of her son Akai as her plotline weaves with the original Frankenstein creature’s quest to subdue humanity (Rickford, 35). In this paper, I will perform a close reading of this work using the theoretical lens of critical race theory and its intersection with feminist theory. My reading will prove that LaValle and Smith’s comic—though it does not have the intent of treating Black women as a “unitary and monolithic entity”—increases a reader’s focus on mother and doctor Josephine Baker in order to portray her rage and grief over Akai’s death at the hands of a police offer (Nash, 8). This analysis of Dr. Baker’s character, combined with LaValle’s usage of allusions and intertextuality, subverts the stereotypically white comic narrative by portraying the lived reality and precarity of many Black individuals within the United States. Through this reading, I will demonstrate that the medium of comics allows for a multifaceted depiction of Black narratives and a new form of literary activism.

Authors: Natalya Misener, John Wolfe. Mentors: John Wolfe. Insitution: Utah Tech University. In our effort to improve education and create a more inclusive learning environment, Natalya Misener and Professor John Wolfe from Utah Tech University are exploring the experiences of neurodivergent students in classrooms. Our goal is to better understand, support, and empower these students, challenging the way things are typically done. We believe it's important to understand that these conditions come in a variety of forms and affect both students and professors in the classrooms in ways that are not currently being discussed, especially as many minorities, especially women and people of color, go undiagnosed and unaccommodated for a variety of reasons. We believe that by educating professors and students alike on how classroom environments can be more supportive of neurodivergent students, we can benefit the entire classroom, including ‘typical’ students. To make this happen, we believe it's important to rethink how we organize our classes, assignments, and interactions, so that we don't have to rely too much on services like the Disability Resource Center (DRC). We have practical suggestions, like adjusting assignments and deadlines and creating a comfortable classroom environment. It's also crucial to be clear in our expectations and listen to what the students need. We ask some important questions, like whether students should consider their instructors' limitations and how students see disabled instructors in their journey to graduation as well. We call for a shift beyond just accommodating neurodivergent students. We want to encourage educators to think about how they can better support all students in their classrooms. It's urgent that we change how we approach neurodivergent students- in order to create a more inclusive, supportive, and successful environment for us all.

Authors: Alexis West Salinas. Mentors: Johnathan Chidester. Insitution: Southern Utah University. There is a growing need to further understand the psychological and physical effects of religiosity among female-identifying members within the LDS church. According to recent studies, as of June 2023, Utah has a Mormon population of 68.55%. Within these statistics, about a fifth of LDS members reported that they have or are currently taking medication for depression. The article also states that 27% of LDS women have depression compared to the 14.5% of LDS men. The church has an infamous reputation with the demonization of mental illness, especially with women. Given the history of society’s treatment of women, women are at an increased risk of suffering within the LDS church. It is important to have the best interests of LDS women in discussing the effects religiosity has on female members within Utah. This paper will analyze the well-being among women of the LDS church as well as assess the specific effects religiosity within Utah may produce surrounding the topics of purity culture, societal expectations, job opportunities, and relationships. This paper will also touch on topics relating to Utah education, LGBTQ+ women within the church, as well as compare and contrast gender roles and sociology. Composing a formulated understanding of these relationships paves the pathway forward in implementing accommodating tools for women within the LDS church in mental health and spirituality.

Authors: Parker Johns, Chandler Warr, Gregory P Nordin, William G Pitt. Mentors: William G Pitt. Insitution: Brigham Young University. Polyethylene glycol diacrylate (PEGDA) microfluidic devices have gained prominence in various biomedical and analytical applications due to their exceptional material properties and compatibility with cell culture systems. However, the presence of residual uncrosslinked PEGDA monomers and photoinitiators within these devices can lead to cytotoxicity concerns, potentially compromising cell viability and experimental results. In this study, we present an innovative approach to reduce cytotoxicity associated with PEGDA microfluidic devices by implementing an isopropanol (IPA) washing method.Our investigation involves thoroughly characterizing the cytotoxicity of untreated PEGDA microfluidic devices and comparing it with devices subjected to the IPA washing procedure. We systematically assess cytotoxicity using cell viability assays and cell proliferation studies to quantify the impact of residual cytotoxic compounds on cells cultured within the microfluidic channels. Our results demonstrate that IPA washing significantly reduces the cytotoxic effects of PEGDA microfluidic devices, leading to improved cell viability and overall biocompatibility.Furthermore, we elucidate the mechanisms behind the reduction in cytotoxicity, shedding light on the role of IPA in effectively removing unreacted PEGDA and photoinitiators. This study provides valuable insights into the optimization of PEGDA microfluidic device fabrication processes, enhancing their biocompatibility and usability for various biological and biomedical applications.In summary, our research highlights the importance of addressing cytotoxicity concerns associated with PEGDA microfluidic devices and offers a practical solution through the implementation of an IPA washing method, ultimately expanding the potential of these devices in diverse scientific and clinical applications.

Authors: Tanner Van Orden, Dennis Shiozawa, Peter Searle, Ana Kokkonen, Paul Evans. Mentors: Paul Evans. Insitution: Brigham Young University. The Bonneville cutthroat trout (Onchorynchus clarki utah) is the only trout species native to the Northern and Southern Snake ranges in Eastern Nevada. Streams on the east side of both ranges flowed into Lake Bonneville 12,000 – 15,000 years ago when Lake Bonneville was at its maximum. As Lake Bonneville retreated, Bonneville cutthroat trout in these streams were left isolated. To better understand how Bonneville cutthroat trout in the study area are coping with a changing climate, we Investigated the genetic diversity of Bonneville cutthroat in the Northern and Southern Snake ranges and compared them to historic samples. We found highly differentiated cutthroat trout populations in close proximity to each other and a genetic diversity loss of up to 86.3% in the last 12 years.

Authors: Jacob Prescott. Mentors: Zoe Thompson. Insitution: Utah Valley University. The pro-opiomelanocortin (Pomc) gene encodes POMC, which is differentially processed to produce adrenocorticotropic hormone (ACTH), beta-endorphin, and three melanocyte-stimulating hormones, among other peptides. POMC neurons are principally located in the arcuate nucleus (Arc) of the hypothalamus, where they are essential in the control of food intake, energy expenditure and body weight. Several different mutations in the POMC gene have been shown to cause early-onset obesity and adrenal cortical insufficiency in humans. We are working with a mouse model with a hypothalamic-specific POMC deficiency. These mice exhibit hyperphagia, early-onset obesity, and also seem to be infertile. We are interested in examining potential differences in pubertal development, as well as reproductive function. Specifically, we will examine day of vaginal opening, day of first estrus, and estrus cycling in juvenile female POMC-deficient mice. The estrus cycle has four stages: proestrus, estrus, metestrus and diestrus. Although hormone levels in the blood differ during the four stages, these are difficult and expensive to measure. A less invasive measurement is to take vaginal cell samples each day and examine them under the microscope. Three different types of cells are present in different ratios depending on the stage of the cycle: nucleated epithelial cells, leukocytes, and cornified epithelial cells. We will track estrus cycle changes during pubertal development and after to see if there are differences between wildtype, heterozygous, and homozygous POMC-deficient mice.Learning more about how POMC-deficiency affects reproductive function may help us understand more about the link between obesity and infertility.

Authors: Heidi Kipp, Annika Jones, . T. Heath Ogden. Mentors: T. Heath Ogden. Insitution: Utah Valley University. The purpose of this research is to identify and document mayfly instars from a parthenogenetic population of individuals being raised in the lab. Instars are the developmental stages of an arthropod between molts. Mayflies (and other non holometabolous insects) go through incomplete metamorphosis, moving from egg to nymph stages, and then to subimago (unique to mayflies), and imago (or adult). Previous research indicates the number of instars to be between 12-45 depending on the species, and the species we studied is estimated to have around 15. During each instar, mayflies shed their exoskeleton. The difference between each instar is vital to understanding the changes in gene expression and overall life cycle of a species. Instars have subtle differences, and identifying them will help further research into which genes are involved in producing specific morphological characteristics. Defining these structures, such as the forming of eyes or wings, are of particular interest in evolutionary phylogenetics. We raised Centroptilum trianguilfer (Ephemeroptera: Baetidae) in a controlled water tank, collecting and dating egg samples from mature imagos. Water is maintained with standard ion composition with 130-400 conductivity. Once the eggs hatched, we performed daily inspections and measurements using a 40x stereomicroscope microscope and Lumenera Infinity Analyze. We are using basic appearance, size and morphology) to separate instars. We will identify and photograph each instar. Samples from the different instars, subimagos, and adults will be acquired and used to generate transcriptome data. We propose that our research will aid in the investigation of mayfly evolution and their genetic mechanisms of control.

Authors: Benjamin Holt. Mentors: York Young. Insitution: Utah Valley University. Our research group aims to create an optical system which generates tunable longwave infrared (LWIR) light as a tool for early detection of disease-indicating molecules in human tissue. This system begins with our newly constructed Nd:YVO4-type laser which generates between five and seven watts of continuous wave optical power in the near IR spectrum. This laser light will be used to drive the subsystem responsible for generating LWIR light: an optical parametric oscillator. In order for wavelength conversion to occur via a non-linear process, the near IR laser power serving as an optical drive must have an intensity on the order of tens of MW/cm2. To achieve such intensities the laser power must be concentrated into high intensity nanosecond length pulses by Q-switching the laser. Our method of Q-switching the Nd:YVO4 laser will be via an acousto-optic modulator in the laser cavity. My work to design the modulator’s kinematic mount, cooling system, and RF driver (as well as characterizing the performance of the modulator for use as a laser Q-switch) is described in this presentation.

Authors: Melissa Rangel, Avery Larsen, Heath Ogden. Mentors: Heath Ogden. Insitution: Utah Valley University. Mayflies, also known as ephemeroptera, are members of the first group of insects that evolved the ability to fly(Gillott, 2005). Distinct developmental characteristics of the life stages of the mayfly are the reason that Ephemeroptera are of particular interest.The aquatic nymph stages do not have wings, but they do possess abdominal leaf-shaped gills, and in some cases gills associated to the legs. The abdominal gills can sometimes be used to help propel the insect through its environment (Eastham, 1936) in addition to performing gas exchange. Centroptilum triangulifer (family Baetidae), will be used for RNA extractions to study the developmental genetic profiles for characteristics such as wings and gills. Objectives for this research are 1). Acquire samples from different instars, subimago, and imago. 2) Perform 10 RNA extractions. 3) Use Qubit technology to ensure ≥ 20 ng/μL RNA concentration per ≥ 10 μL. 4) samples will be packaged in thermo-stable shipping boxes and sent to Novogene where samples are tested once more for quality control. 5) Once quality is confirmed, samples will be sent and processed by Novogene. 6). Using an in-house bioinformatics workflow, RNA data will be checked for quality, trimmed, aligned, and assembled. The assembled contains will be used to search for genes of interest. 7) the resulting RNA expression profiles will be compared across the installs, sub imago, and imago and to other expression profiles from other related insects.

Authors: Samantha Curnow, Carl Hjelmen. Mentors: Carl Hjelmen. Insitution: Utah Valley University. The genome sizes of insects vary immensely; some insects have only 100 million base pairs, while others reach nearly 18 billion base pairs. Many selective pressures can have an influence on genomes, but we still lack a clear understanding of which selective pressures cause such variation in genome size even within well-studied groups. To determine the influence of environmental factors on this variation, we investigate the relationship between genome size and the average natural environment of 152 Drosophila species. The nature of the relationship between genome size and environmental factors is investigated using phylogenetic models and linear analyses such as phylogenetic generalized least squares analysis. We collected data from peer-reviewed papers and publicly available datasets, such as karyotype.org and WorldClim, to compare the genome size of each species to the temperature, altitude, humidity, etc. of their natural environments using linear phylogenetic models. The distribution of these species was also visualized using geographic and biological analysis packages in R, such as geodata, to extract environmental data of specified regions, and phytools in combination with caper to run phylogenetic comparative analyses.

Authors: Stephen Chamberland, Craig D. Thulin, Katherine Solorzano, Cassandra Beddes, Nathan Twitchell, Abram Caruso. Mentors: Steve Chamberland, Craig D. Thulin. Insitution: Utah Valley University. This investigative procedure is a continuation of an experiment done by UVU undergraduate student Kyra Banks and her mentor, UVU Professor of Chemistry Craig Thulin, to determine the structure of xanthommatin. Xanthommatin is one of the primary pigments found in monarch butterflies, and many other insects. Data obtained during the mass spectrometric analysis was observed to indicate a possible deamination of xanthommatin, however the quantity of deaminated xanthommatin observed was too small and so the structure could not be determined. The research investigates the precedented deamination of kynurenine as a model to develop a procedure for the deamination of 3-hydroxykynurenine, primarily due to the fact that it is cheaper in price to xanthommatin, as well as a chemical precursor that can be used for the synthesis of xanthommatin. The implications of this suggest that the deamination procedure developed for 3-hydroxykynurenine could be successfully replicated with xanthommatin. After the deamination procedure has been successfully repeated, xanthommatin will be synthesized using one of a few procedures developed by Kumar, A., et al1. Once a sufficient sample of xanthommatin has been successfully synthesized, the deamination procedure will be repeated on samples of xanthommatin to determine the structure of deaminated xanthommatin using NMR spectroscopy. The research conducted here is beneficial not only because it is a continuation of other UVU student’s and staff’s work, but also to those whose work is in the animal biology realm of science. The information that will be extracted from this research will spearhead new research pathways and questions to be explored.Xanthommatin-Based Electrochromic Displays Inspired by Nature (acs.org)Biomimetic Colorants and Coatings Designed with Cephalopod-Inspired Nanocomposites (acs.org)

Authors: Jacob Sampson, Joshua Goates, Brian Patchett, Abolfazl Amin, Bonnie Andersen. Mentors: Bonnie Andersen. Insitution: Utah Valley University. Noise from an interstate can reach extreme levels. The OSHA limit for when sound becomes dangerous for the health of individuals is 85 dB. At UVU there is a pedestrian bridge that goes over I-15 and the students and other pedestrians that use this bridge are exposed to sound levels that could be potentially dangerous for their hearing, along with other adverse health effects due to sound on a regular basis. Sound levels have been measured on the bridge using two different measuring devices. The first being an Extech noise dosimeter, that was worn on the shoulder of the measurer as they walked across the bridge. The second instrument used was a Larson David sound level meter. That was placed on several places along the length of the bridge at set to record for several minutes to get the sound levels at those places. Sound levels that have been recorded have ranged form 79 dB to 102 dB. The OSHA limit for occupational exposure at 100 dB is two hours while for non-occupational exposure it is only 15 minutes. This research seeks to better understand and quantify the noise exposure pedestrians experience on the bridge. Also this research hopes to find out what facts influence the sound levels on the bridge and we hope to compare our experimental results to an ANSYS model of the bridge to confirm our findings.

Authors: Spencer Brown, Shawn Pepper, Carson Draughon, Ulises Thornock, Dustin Shipp. Mentors: Dustin Shipp. Insitution: Utah Valley University. In the shadow of the 2021-2023 global energy crisis, the need for alternative sources of energy has reached an all time high. To combat this, we have developed a prototype method of harvesting kinetic energy from a door swing, converting that energy into electricity, and storing it inside a battery for future use. Our experiments have demonstrated the capability to use the energy from one door to charge a cellular phone, but we believe this method could be applied on a much larger scale. In this poster we will discuss the method, design, and measurements from our device, as well as possible future applications.

Authors: Miranda Rose, Daniel James. Mentors: Daniel James. Insitution: Utah Valley University. In this study, we investigated mechanical vibrations as a mechanism for creating uniform droplets in a free liquid jet. A stream of liquid naturally breaks into irregular droplets as it falls due to the Plateau-Rayleigh instability. In this work, droplet break-up was triggered by utilizing a motor with Arduino-based frequency control and stroboscopic visualization. The project achieved uniform droplet sizes for multiple liquids of different viscosities. Notably, this method demonstrated the creation of Dippin Dots-like confections at a STEM fair, engaging learners in the principles of physics and engineering. Future work will focus on the original goal of utilizing acoustics for droplet formation, aiming to refine the process and expand its industrial applicability.

Authors: Lauren Silvatti.. Mentors: Zoe Thompson. Insitution: Utah Valley University. Proopiomelanocortin (Pomc) deficiency, stemming from a mutation in the Pomc gene, presents a myriad of health challenges, including extreme hyperphagia, early-onset obesity, and infertility. This study leverages a mouse model exhibiting Pomc-deficiency to delve into the root causes of infertility. While the correlation between obesity and fertility is well-established, our primary focus is to discern whether the POMC mutation independently contributes to reproductive challenges. Our investigation extends into the interplay of genetics, endocrinology, and obesity through data analysis using R, with an emphasis on deploying advanced statistical models.Video recordings of sexual behavior interactions have been analyzed manually, with independent observers marking each behavior. The frequency and duration of each behavior will be compared among three groups of pairings: wildtype-wildtype, heterozygote-heterozygote, and homozygous POMC-deficient mice. Techniques will include data cleaning, timestamp manipulation, and behavior categorization in R, a programming language commonly used for data analysis. To discern patterns and variations, our analysis will also employ statistical models such as linear mixed-effects models. We can account for potential confounding variables and significant differences in durations of previously identified important reproductive behaviors. Visualization tools, including box plots and violin plots, will provide an initial glimpse into the distribution of behavior durations. Subsequently, we plan to conduct inferential statistics, employing techniques such as Analysis of Variance (ANOVA) to assess the significance of differences across multiple groups. Our investigation extends beyond descriptive statistics, with a focus on predictive modeling. Regression analyses will explore potential relationships between behavior durations and reproductive success. Machine learning algorithms will be applied to uncover complex interactions within the dataset.The anticipated results promise not only a nuanced understanding of the interplay between Pomc mutations and reproductive challenges but also the identification of potential biomarkers or predictors of successful reproduction. This comprehensive statistical approach contributes significantly to the fields of genetics, endocrinology, and obesity research, offering a robust framework for future investigations into the intricate relationship between genotype and behavior.

Authors: Kaycie A Melville, Ashley N Egan, Yu Ya Liang. Mentors: Ashley N. Egan. Insitution: Utah Valley University. Phaseolus vulgaris (common bean) and P. lunatus (lima bean) provide protein and nutrition for millions of people across the globe. Native to the New World, these cultivated species present unique histories of multiple and independent domestications in Mesoamerica and the Andes. Brazil is the leading producer globally of these beans. With both wild and cultivated landraces present, Brazil may act as a secondary center of domestication for these two economically significant leguminous crops. Brazil's indigenous populations’ cultivation efforts may include both wild and cultivated germplasm, potentially contributing to the continued domestication of these crops to create novel shapes, sizes, and colors that are grown and hand-selected by the natives in these regions. To investigate Brazil as a secondary domestication center of beans, this research addresses several key questions: Are signals of past and current domestication processes discernible in current Brazilian cultivars of these species? Can we unravel the relationships between these Brazilian crops and their primary centers of domestication? What genetic differences are underpinning domestication? How diverse are Brazilian cultivars? How do they relate to wild and related material and species? This work focuses on 48 accessions of P. lunatus and P. vulgaris from Brazil, including wild material and two accessions from two related species, P. polystachios and P. filiformis from North America. Whole genomes were resequenced using Illumina sequencing and compared against the published genome of Phaseolus vulgaris to identify SNPs in each accession. Whole chloroplast genomes were also assembled and compared. Phylogenetic analyses, network analyses, population structure, and tests for neutral and positively selected mutations were conducted, revealing distinct clades for both P. vulgaris and P. lunatus with clear links to their Andean and Mesoamerican origins. Genetic diversity was assessed both within (cultivated vs wild) and between P. vulgaris and P. lunatus, demonstrating significant variations, not only between species but also within each species, suggesting the influence of diverse selection pressures and local adaptation during the domestication process. McDonald-Kreitman tests analyze and locate possible domestication genes from the library of SNP’s between outgroups (Phaseolus filiformis and Phaseolus polystachios) and between species. Overall, this research advances our understanding of the intricate process of domestication in P. vulgaris and P. lunatus, highlighting potential ongoing domestication in Brazilian cultivars, unraveling their genetic relationships, and shedding light on the complex interplay of genes that underpin domestication and diversity. These findings contribute to the broader understanding of crop evolution and have practical implications for crop improvement and conservation.

Authors: Anna Wilkinson, Feyan Hoffman, Roshan Abraham. Mentors: Daren Nelson. Insitution: Utah Valley University. Remote sensing technologies, involving drone and satellite imagery, have recently begun to be used in hydrologic research with various applications. The technology is relatively easy to obtain, is noninvasive, and helps minimize cost, access, and safety concerns related to the study of wetlands. The thermal and multispectral imagery can provide unique datasets that expand understanding into groundwater and surface water interactions. As part of this project, we are exploring remote sensing applications within the hydrology of wetlands surrounding Utah Lake, a large freshwater lake within Utah Valley. The project has involved the collection of thermal and multispectral drone imagery from 2021 to 2023. Thermal imagery collected in these areas has assisted in the determining of hot and cold spring locations and how these springs have shifted due to changes in groundwater levels and lake levels. In addition, this imagery has shown how physical anthropogenic influences have also impacted the location and stream channels associated with these springs. Multispectral imagery is used to understand the health of phreatophytes near the lake during dry and wet years to be used as an indicator for groundwater level changes. Even though much of the data is still preliminary and part of a long-term study these remote sensing technologies are already showing how these groundwater systems adapt to seasonal and anthropogenic changes.

Authors: Cole Statham, Katelyn Thomas. Mentors: Michael C Rotter. Insitution: Utah Valley University. Datura (Solanaceae) is a potent hallucinogenic genus of plants that has varied uses across cultures. Tropane alkaloids in these plants are potent compounds that, depending on dosage, can offer the user a psychoactive experience or cause severe reactions including death. For some, Datura is little more than an ornamental flower or an ideal source to have a psychedelic experience. While for others it is a sacred plant, used on special occasions, and only permitted to be handled by those who have been prepared and trained to do so. An explanation for these cultural differences could be that cultures with taboos surrounding this plant are likely those that have species of Datura with variable levels of tropane alkaloids, while cultures without taboos are likely to have species with consistent levels of tropane alkaloids. Here we focus on six species of Datura using literature reports of tropane alkaloid contents and compare the variability in these phytochemicals to cultural uses of these plants. We predict that societies with cultural taboos will be more likely to be those with species that have higher variability in tropane alkaloids.

Authors: Vy Dao, Devin Taylor, Danielle Taylor. Mentors: Devin Taylor, Danielle Taylor. Insitution: Utah Valley University. Epilepsy is one of the most common neurologic disorders affecting about 60 million people worldwide (Chen et al., Poduri and Lowenstein, 2011). Currently in the field, there are various methods being used for mechanical seizure induction using Drosophila melanogaster. This variability makes it difficult to compare findings from different research studies. We employed various mechanical seizure induction techniques currently used in Drosophila epilepsy research. We focused on both group testing as well as individual testing using different anesthesia parameters. For individual testing, epileptiform activity and locomotor activity were recorded in adult male Drosophila through mechanical seizure induction using a vortex assay at either 24-hours post- or 1-hour post-CO2 anesthesia. We also evaluated the time for 50% of adult drosophila recovery as indicated by a group climbing assay (10 flies per group) following mechanical seizure induction using a vortex assay at either 24-hours post- or 1-hour post-CO2 anesthesia. Finally, for each of the above testing parameters, we not only tested wild-type (WT) flies, but also multiple positive control seizure phenotype flies commonly used in mechanical seizure induction studies using Drosophila melanogaster. We found significant effects in both CO2 induction methods as well as in different genetically induced seizure phenotypes.

Authors: Gregory Skinner. Mentors: Yi Yin. Insitution: Utah Valley University. Materialism and consumerism have been linked to higher levels of loneliness, an increased focus on extrinsic goals, various social challenges, and lower overall well-being of individuals (Fumagalli et al., 2022; Pieters, 2013). Previous research has linked people with higher levels of consumeristic/materialistic values to a lower frequency of intrinsic and pro-social pursuits (Nurhajayanti, 2019; Sheldon & Kasser, 2018). The area of discussion has primarily often looked at relationships and societal-level challenges separately and has a limited assessment of platonic personal relationships. This study adds to this discussion by addressing the gap in more friendship-oriented relationships, looking at how the same set of individuals are affected in both personal and societal connections, as well as seeing how various individual factors, such as religious affiliation and socio-economic class may impact these effects. This research will use mixed research methods, including surveys and in-depth interviews, to see how individual attitudes toward consumerism relate to their behavior and values toward their immediate social circle and larger communities. The samples were gathered from among the United States population and were collected at random through the use of online collection methods. The participants were contacted through the use of snowball sampling as well as the use of online platforms which include SurveySwap and SurveyCircle to acquire representative samples. The survey data will be examined through the use of multiple regression analysis. The interview data will be reviewed through thematic analysis. The addition of this study will increase our understanding of not only how consumerism and materialism affect the individual’s well-being but also their capacity to meaningfully connect with their various communities.

Authors: Sage Wettstein, Kaicee Postler, Rachel Arocho, Julie Nelson. Mentors: Kaicee Postler. Insitution: Utah Valley University. Research has shown the efficacy of improving and strengthening family relationships through family life education programs (FLE; Darling, et al., 2019). The Stronger Families Project (SFP) at Utah Valley University (UVU) is a FLE program offered to the community to provide skills regarding communication, problem solving, conflict resolution, and general family function (Stronger Families Project, 2023). The current study aims to identify qualitative themes of satisfaction among participants from SFP across three semesters, including Fall 2022, Spring 2023, and Fall 2023. Qualitative data has been taken from satisfaction surveys administered in the final session of the program to determine the elements of the SFP program that have the most positive effects on families. Thematic analysis will allow for comprehension of the data in an aggregate form, with specific quotes to support identified themes. Implications for future research and practice will be discussed based on identified themes.

Authors: Alexa Bailey, Sophie Daines, Joshua Bennett, Carlos Moreno, Scott Weber. Mentors: Scott Weber. Insitution: Brigham Young University. As the understanding of cancer pathophysiology continues to increase, there is an increased focus on the role of T cells in targeting cancerous cells and tumor sites. Recently, it was demonstrated that CD5, a transmembrane glycoprotein found on T cells, plays a key role in negatively regulating T cell activity. CD5 also significantly impacts T cell metabolic profiles by increasing oxygen consumption rates (OCR) and extracellular acidification rates (ECAR). We are now investigating the role of CD6, a related membrane protein found on T cells, and its effect on regulating T cell proliferation and metabolism by measuring the proliferation rates and metabolic profile of T cells from a CD5/CD6 double knockout murine model. Because tumor microenvironments are vitally important in determining the immune system’s response to cancer, differences in metabolism may yield new insights for developing immunotherapy techniques.

Authors: Benjamin VanDreew. Mentors: Kal Munis. Insitution: Utah Valley University. America as we know it today is politically very polarizing, divided, and full of misinformation. In this climate, buzzwords have become as prominent as ever either being spouted by politicians or news outlets or even trickling out to the public. In 2023 the word “woke” became a popular buzzword and is used in all sorts of contexts. So much so that in a lot of ways “woke” has lost any of its original meaning that was trying to be conveyed. In this study, I am out to discover what “woke” really means to Americans from all different walks of life. We have set up a conjoint list experiment that will be sent out in the form of a survey featuring randomized options. We will be able to get a better look at what aspects of American life people feel are the most “woke” and help define what the buzzword really means. This research will give us a deeper look into modern American culture and help provide clarity to this polarizing subject.

Authors: Travis Christensen, Geoff Zahn, Alma Laney. Mentors: Alma Laney. Insitution: Utah Valley University. In July 2022, green cabbage plants (Brassica oleracea) were observed with severe viral symptoms in a local community garden in Utah County. These plants were observed to be covered with cabbage aphids (Brevicoryne brassicae). Symptoms observed on the cabbage plants included yellowing, necrotic lesions, and brittle necrosis of the leaves. These symptoms have been found to be transmissible by the cabbage aphid to broccoli, cabbage, and kale, although symptoms are delayed in kale. Work is being done to find other transmissible plants within the brassica family. Sequencing of RNA yielded no results, however, amplification of viral DNA via rolling circle amplification (RCA) has yielded positive results. A sample obtained through maintenance of the virus and cabbage aphid is currently being subjected to RNAseq using the NovaSeq Illumina platform. Through several virological methods we are able to conclude the presence of a putative geminivirus transmissible through cabbage aphid in our affected plants. To our knowledge, this is the first report of an aphid-transmissible DNA virus of brassicas in Utah. Further work is being done to further identify, classify, and build the genome of this specific virus using Illumina sequencing.

Authors: Ezra Wylie, Merrill Halling. Mentors: Merrill Halling. Insitution: Utah Valley University. Various parts of Cercocarpus ledifolius, or curled leaf mountain mahogany, was used for medicinal purposes by Native Americans for a wide variety of uses including tuberculosis, syphilitic sores, and venereal diseases. Symbiotic microorganisms, called endophytes, often produce these compounds for defense of the tree. Novel compounds have been found in plants which have demonstrated antibiotic, antifungal, or other biological activities. Endophytes were grown from various parts of the tree, including roots, stems, branches, and leaves. The bioactive compounds were isolated and identified using chromatographic and spectroscopic methods.

Authors: Megan Ritter Martin, Alley Fausett, Kristin Davenport, Malisa Brooks, Kent Hinkson. Mentors: Malisa Brooks, Kent Hinkson. Insitution: Utah Valley University. AbstractBackground: Present-day college students confront record-high levels of anxiety. In 2022, 36.9% of college students reported that anxiety affected their academic performance compared to 21.9% in 2015. This surge in anxiety presents a pressing concern. Prolonged anxiety poses a significant risk, potentially triggering various mental health challenges, including substance abuse, depression, and suicidal ideation and behaviors. Moreover, the adverse impact of anxiety on concentration and learning can result in academic difficulties that can persist throughout one’s life. Despite ongoing research, the correlation between anxiety and its influence on students’ academic performance remains inconclusive, primarily due to conflicting findings in prior studies within this domain.Methods: This study was designed to investigate the connection between academic achievement and anxiety, specifically in college students. A total of 1,359 University students from various US universities participated in this study from 2021 to 2022. Anxiety was measured by the General Anxiety Disorder 7 (GAD-7) scale, and academic performance was measured by Grade Point Average (GPA) and other markers of academic performance. To investigate potential mediating pathways, zero-order correlations were used to analyze the relationship between variables of interest. Further, t-tests were used to examine differences in key variables among demographic groups (e.g., veteran status, gender, race, ethnicity, etc.).Results: There was no statistically significant relationship found between students' academic achievement and their degree of anxiety. However, several academic performance variables besides GPA had inverse associations with anxiety. Further, several deleterious academic activities (for instance, “turning in a paper or assignment late”) were shown to be moderately associated with anxiety. Considered together, these findings suggest that anxiety has a complicated relationship with the GPA of the student, but multiple pathways connect it to academic performance.Conclusion: The present study contributes to the current literature surrounding the relationship between anxiety and academic performance. While traditionally, research into academic performance often focuses solely on GPA, additional academic performance variables were explored, providing insight into other relationships of potential significance. This creates an opportunity wherein the field may be able to better understand and support students by recognizing the impacts that anxiety has on their academic performance. These results highlight how crucial it is to treat mental health issues to improve university students' academic performance.

Authors: Emily Cherrington, Sam S Ingram, Chloe E Loveland, Ryanne Welch. Mentors: Olga Kopp. Insitution: Utah Valley University. Ocimum basilicum, commonly known as Genovese basil, is a frequently grown herb in the Lamiaceae family. It is used in food cuisines around the globe and is easily grown as a fresh-market herb for restaurants, farmer’s markets, and grocery stores. Basil has many antioxidants and anti-bacterial properties, but it is most commonly used as a culinary ingredient to add flavor to various dishes. Basil is very sensitive to cold, requiring well-draining soil with temperatures of 18°C to 27°C for germination. Consistent soil moisture is also necessary for optimum growth, and it prefers to stay moist to keep from drying out. In the face of global climate change, it becomes imperative to determine the adaptability of crucial agricultural crops -like basil- to varying nutrient levels in different substrate types across diverse environmental conditions. A plant's capacity to thrive in distinct substrates is intrinsically linked to the unique requirements of its seeds. The choice of substrate serves as the foundational element for cultivating healthy plants. This study centers on examining three pivotal aspects related to substrates: moisture retention, nutrient accessibility, and fungal growth. This led us to question whether the germination success of Ocimum basilicum differs depending on the substrate type. To test this question, we will plant Genovese basil seeds in four distinct substrate types: standard germination mix, 80/20 peat-perlite blend, compost-enriched soil, and an agar medium. Following their placement in the respective substrates, all seeds will be grown in a controlled growth chamber, subject to identical lighting conditions and a consistent temperature of 22°C to ensure uniformity across all treatments. At intervals of 1-2 days, diligent observations will be made to detect signs of germination. Once germination becomes apparent, we will meticulously document the results. Subsequently, this collected data will undergo analysis using the R Language. We anticipate that substrates rich in nutrients (specifically agar and standard germination mix) will exhibit heightened germination success. Investigating how substrate type affects the germination success of Genovese basil offers valuable insights with broad applications in horticulture and agriculture. It can enhance agricultural practices by pinpointing optimal soil choices for specific crops, increasing substrate efficiency to minimize resource wastage, and promoting sustainable and economical cultivation methods. Furthermore, this research contributes to a deeper comprehension of the environmental ramifications of crops and the diversity of crops in both controlled laboratory settings and natural environments.

Authors: Noah Christensen, Matt Olson. Mentors: Matt Olson. Insitution: Utah Valley University. Geologic maps serve as a valuable tool with diverse applications, one of which is resource exploration. Understanding available resources in America is beneficial for enhancing energy security, environmental sustainability, and economic growth. As political discourse rises, it is crucial to address national security concerns and head towards short- and long-term goals of energy independence. Traditional geologic mapping is characterized by time-intensive and high-cost fieldwork, but through multispectral and hyperspectral remotely sensed imagery it is possible to instantly map extensive areas using unique absorption patterns of minerals in the reflected spectral signature of the electromagnetic spectrum. This study explores an intercomparison of mineral mapping using Hyperion (EO-1), ASTER, and AVIRIS imagery in the Marysvale Volcanic Field, Utah. The satellites and high-altitude aircraft were chosen due to their varying number of spectral channels, spectral ranges, and spatial resolutions, allowing for a cross-analysis of their strengths, weaknesses, and overall capabilities. While previous studies have utilized AVIRIS and ASTER imagery within the Marysvale Volcanic Field, no prior research has explored a comparison of mineralogical maps using these sensors at a specific location. All analysis will be conducted through open-source applications to promote accessibility in future research and reproducibility of image generation through the sharing of R code. This research will enhance our comprehension of the necessary spectral and spatial resolutions for generating accurate mineral identification. Published geologic maps and in-situ field samples were used to validate the generated maps. We expect to find one of two outcomes: a strong contrast in classified mineralogy depending on the image source used, pointing towards a need for higher spatial and spectral resolutions to achieve accurate mapping, or minimal variation in classification, indicative of an unnecessary number of spectral bands. Developing accurate and accessible mineral mapping tools may be the next step in strengthening our knowledge of resource availability, without the need for rigorous traditional mapping methods.

Authors: Austen Miller, Josh Leon, Geoffrey Zahn. Mentors: Geoffrey Zahn. Insitution: Utah Valley University. The Pando aspen grove in Central Utah is a remarkable organism comprising a clonal colony of Quaking Aspen (Populus tremuloides) in Fishlake National Forest. While Pando has garnered plenty of attention, the role of the fungal microbiome within this clonal system remains relatively uncharted. This research project delves into the endophytic and epiphytic fungal communities inhabiting the leaves of this giant single organism. The clonal nature of Pando means that plant genotype is consistent across a broad area, allowing us to test hypotheses about how plant-associated fungi disperse and associate with their hosts. In particular, we are testing whether proximity to a forest edge affects foliar fungal community structure. This research will enhance our understanding of how forest patch size and location contribute to plant-fungus community formation. These findings may also have implications with the potential to affect the health and resilience of this aspen clonal colony, which could in turn inform conservation strategies and forest management in the face of environmental challenges and the shifting ranges of aspens and fungal symbionts.

Authors: Emmaline M Saunders, Michael A Stearns, Ami Ward. Mentors: Michael Stearns. Insitution: Utah Valley University. The Tuolumne Intrusive Suite (TIS), Sierra Nevada, California, accumulated magmatic rock from 95 to 85 Ma. Ar-Ar biotite dates require that temperatures within the TIS remained above ~300°C until ~79 million years ago. The protracted thermal history resulted in five texturally and chemically distinct units that young towards the center and was recorded by chemical and isotopic re-equilibration of the minerals. Challener and Glazner (2017) demonstrated that amphibole phenocrysts from the Half Dome Granodiorite (Khd) experienced greenschist-facies metamorphism. Amphibole phenocrysts host abundant inclusions of biotite, chlorite, feldspar, titanite, epidote, and apatite, which are interpreted to have crystallized via breakdown of magnesiohornblende. Additionally, Al zoning suggests fracturing and subsequent healing of the amphibole crystals occurred at near- or subsolidus temperatures. New EPMA and LASS-ICP-MS analyses of texturally related amphibole, titanite, feldspar, and biotite from the equigranular Khd place limits on the timing of amphibole breakdown and contextualize the low-temperature re-equilibration of many of the major minerals in the rock. Most of the amphiboles analyzed contain 0.5–6 wt. % Al2O3 corresponding to actinolite compositions, while feldspar pairs record ~475 ºC apparent temperatures. Titanite grains (re)crystallized between 91–80 Ma and contain 25–825 ppm Zr, which correspond to apparent temperatures between 550–710 ºC (150 ± 50 MPa, aTiO2 = 0.5 ± 0.1). The distribution of Zr in titanites is bimodal with the majority having <200 ppm Zr. Titanites younger than 87 Ma have decreasing Zr content and titanites included within actinolite amphibole contain the lowest Zr content (25–50 ppm) and youngest dates (85–80 Ma). Melt-present crystallization of titanite began at ~91–90 Ma, followed by both near and subsolidus (re)crystallization from ~88–86, concluding with titanite growth via hornblende breakdown from 82–80 Ma. These data taken together with previous investigations provide a continuous record of the rock’s chemical evolution driven by incremental emplacement and subsequent episodic autometamorphism of the equigranular Khd, and critically, any inferences regarding magmatic processes in the TIS must first account for the metamorphic re-equilibration of the rock.

Authors: Arahi Perdomo, Brooklyn Moore, Erin Kerr, Hula Santiago, Kylie Kay, Sarahi Joyner. Mentors: Krista Ruggles. Insitution: Utah Valley University. This research initiative centers on the experiences and learning outcomes of preservice teachers (PSTs) from Utah Valley University who volunteer to teach in the San Juan School District (SJSD) and the Navajo Nation. Our primary aim is to understand how this cross-cultural teaching experience shapes their future teaching practices, perspectives on diversity, and inclusion in education.Preservice teachers play a critical role in the future of education This study examines how their participation in a unique cultural context can enhance their preparedness as educators. By engaging in volunteer teaching assignments within the Navajo Nation, these students gain exposure to diverse cultural backgrounds; fostering cultural awareness and sensitivity.We seek to show the transformative impact of this experience on their personal and professional growth. Through interviews and observations, we will explore the challenges and opportunities faced by preservice teachers and how this experience influences their teaching philosophies and aspirations.Our ultimate goal is to determine how such immersive experiences can contribute to the development of culturally responsive pedagogy. We believe that these preservice teachers, with their enriched perspectives, can become advocates for diversity and inclusion not only within their classrooms but also within the broader educational landscape and society.This research holds the potential to inform teacher education programs and policy discussions regarding the value of cross-cultural experiences in teacher preparation. By shedding light on the impact of volunteer teaching in the Navajo Nation, we hope to contribute to the ongoing dialogue on fostering more inclusive and culturally aware educators, ultimately benefiting students and society as a whole.

Authors: Chance Witt, Devan Hill. Mentors: Jianlong Han, Seth Armstrong, Sarah Duffin. Insitution: Southern Utah University. We study the steady state solutions of a Lotka-Volterra model with crowing effects when delta=2. A nonstandard numerical scheme is proposed, and numerical experiments predict the long term behavior of the numerical solution.

Authors: Webster Madison, Oldroyd Kristina, Shubert Jennifer. Mentors: Shubert Jennifer. Insitution: Utah Valley University. Recent societal events have become benchmarks for understanding how young people interpret and engage with broader social issues. For example, the 2016 election revealed a heightened awareness of systemic racism, inequity, and oppression among youth disapproving of Trump’s presidency, with Latinx groups in particular demonstrating awareness of racism and discrimination across marginalized groups.Furthermore, the Supreme Court’s historic decision to overturn Roe v. Wade ignited nationwide discourse on social issues such as women’s reproductive rights and bodily autonomy, with some interpreting the ruling as perpetuating systemic oppression, a form of cultural imperialism and power imbalance, disproportionately affecting marginalized groups’ access to safe and legal abortions. This study utilizes Young’s (1990) multifaceted oppression framework to investigate how emerging adults demonstrate awareness of oppression in interpreting and responding to societal events.Data came from 104 undergraduate students (Mage= 21.74; 72% Female; 91% White) identifying as conservative, moderate, or liberal. This study collected data from a longitudinal sample through a Qualtrics survey distributed within hours of the Supreme Court decision. Participants responded to open-ended questions regarding their feelings, views, and potential changes in attitudes and behaviors due to the overturn. By applying a coding scheme based on Young’s framework to the narrative responses, evidence of all five dimensions of oppression emerged. Intriguingly, marginalization (i.e., limiting full participation in society) constituted the most prevalent theme, appearing in 52 responses opposing the overturn and 10 supporting the overturn, followed by powerlessness (i.e., inability to make decisions regarding oneself), arising in 40 opposing and 22 supporting narratives. Next, 37 opposing and 33 supporting responses highlighted cultural imperialism (i.e., valuing and enforcing dominant cultural norms). Then, 38 opposing and 8 supporting responses expressed violence (i.e., intentional harm or threat). Finally, only 22 opposing and 8 supporting responses illustrated exploitation (i.e., systemic transfer of resources). These findings suggest that participants across the political spectrum expressed complex reactions to the decision’s ramifications. Evidence of all five facets of oppression in participants’ narratives may shed light on the potential for heightened critical consciousness among individuals navigating the complexities of a post-decision landscape. Further theory building is necessary to understand how young people develop a critical awareness of significant social events and their impact on critical consciousness. Moreover, these findings establish a foundation for advancing critical consciousness theory, particularly concerning period effects and the development of awareness regarding structural privilege, oppression, and inequity.

Authors: Ian Macapagal. Mentors: Joshua Price. Insitution: Southern Utah University. The issue of suicide in the United States constitutes an increasingly concerning economic and public health issue, given the observed rise in suicide rates in recent years and the societal costs incurred by suicides. This paper focuses on the incidence of suicides by firearm, given firearms’ comparatively high usage and lethality in suicides, and investigates the effects of mandatory waiting periods for firearm purchases on the incidence of suicide. Such purchase delays theoretically provide a “cooling off” period, temporarily denying impulsively suicidal individuals the means to commit suicide. This study employs multivariate regression analysis to isolate the effects of having state-level mandatory waiting periods for firearms purchases, as well as the length of such periods, on state-level suicide mortality rates. This analysis is conducted with the aim of investigating the effectiveness of these policies in reducing firearms-related and total suicides, in addition to the extent to which suicidal individuals respond by substituting firearms for other methods.

Authors: Cate Miller, Tyler Free, Brad Bundy. Mentors: Brad Bundy. Insitution: Brigham Young University. Diagnostics are an essential tool in the treatment path for many different types of cancer. They are used to determine the progression of cancer treatment and are critical to increase survival rates. The most common diagnostics are often too expensive or sophisticated to be used on a widespread scale. Using a cell-free protein synthesis system to create a biosensor as a diagnostic can drastically decrease costs, increase convenience, and increase survival rates. We previously engineered low-cost CFPS systems to detect glutamine which would be useful for low-cost biosensing of clinically relevant glutamine concentrations. This work reports our progress in optimizing the CFPS glutamine biosensor for improved performance.

Authors: Riley B. Jackson, Iris Cepeda. Mentors: Michael C Rotter, Kiara Whitley. Insitution: Utah Valley University. Roses (Rosa spp.) are beloved ornamental plants known for their flowers and for their formidable prickles, often referred to as thorns. These prickles are an important part of herbivore resistance in these plants. These mechanical defense structures can vary in shape and abundance and are found along the length of the stems and even the underside of leaves. Although the mere presence of these prickles can cause damage to potential herbivores they also may act as vectors for infectious microbes. Previous studies have shown that other piercing physical defense structures can harbor infectious bacteria, sometimes resulting in conditions such as gangrene, anthrax poisoning, or septic arthritis. This raises the question about their potential implications for human safety particularly when these plants grow in areas of high human use. While roses have similar sharp structures, it is currently unknown if they harbor any pathogenic or defensive bacteria. Our study explores and whether local roses (both native and non-native) have similar or distinct microbiomes and if they possess pathogenic microbes. Understanding these differences would enable us to shed light on ecological relationships between microbes and native versus non-native plants and health risks associated with rose prickle injuries.

Authors: Olivia Frary, Carl Hjelmen. Mentors: Carl Hjelmen. Insitution: Utah Valley University. Previous work has shown that there are significant differences in lifespan between sexes of the same species. Whether it is an XY or ZW system, the heterogametic sex dies earlier. There are thought to be many factors that contribute to the difference in lifespan between the sexes. This research aims to investigate this relationship further by digging deeper into the degree of differences between the heteromorphic sex chromosomes. We want to determine whether the degree of differentiation correlates with the lifespan differences in species. The comparison of total genome size between the sexes of multiple species are used to find the difference in the size of their sex chromosomes, which is then compared to longevity data on the species to determine a relationship. This genome size data comes from publicly available databases and literature. These comparisons are made using comparative phylogenetic methods in order to account for evolutionary relatedness utilizing a newly constructed phylogenetic tree. All analyses are completed in R and include PGLS (Phylogenetic Generalized Least Squares) and measures of phylogenetic signal (Pagel’s lambda, Blomberg’s K). We will discuss the results of the comparative phylogenetic analyses and any patterns seen regarding longevity.

Authors: Garrett Johnson, Tyler Free, Brad Bundy. Mentors: Brad Bundy. Insitution: Brigham Young University. Acute Lymphoblastic Leukemia is the most common form of childhood cancer. Asparaginase treatment has greatly improved survival rates to 80%. Survival rates increase by an additional 10% when diagnostic treatment monitoring is used to guide treatment administration. Cell-free protein synthesis is a technology capable of detecting Asparaginase in human serum. However, RNases from human samples destroy CFPS activity. RNase inhibitor can be produced at a low cost by the CFPS system to rescue in-vitro protein synthesis activity to enable biosensing. This work reports our work toward developing an at home Asparaginase diagnostic that would enable personalized dosing of Asparaginase and further improve survival rates of Acute Lymphoblastic Leukemia.

Authors: Kiersten Gardner, Hannah Duffy, Abbey Blair, Nicholas Ashton, Porter Stulce, Dustin Williams. Mentors: Dustin Williams. Insitution: University of Utah. Transdermal antiseptic products as a method to decrease skin bioburden prior to surgeryKiersten Gardner(1,2), Hannah Duffy(1,2), Abbey Blair(2), Nicholas Ashton(2), Porter Stulce1(2), Dustin Williams(1,2,3,4)1 Department of Biomedical Engineering, University of Utah, Salt Lake City, UT2 Department of Orthopaedics, University of Utah, Salt Lake City, UT3 Department of Pathology, University of Utah, Salt Lake City, UT4 Department of Physical Medicine and Rehabilitation, Uniformed Services University, Bethesda MDIntroduction: Preoperative skin preparation (PSP) kits are used before surgery to prevent surgical site infection (SSI). These kits consist of alternating scrubs of alcohol and Chlorohexidine Gluconate (CHG) or Povidone Iodine (PVP-I). Transdermal antiseptic products like Ioban, Tegaderm, and Surgiclear are also used clinically to eradicate skin bacteria by releasing antiseptic over time. Despite these precautions, infections often occur, usually stemming from a patient’s endogenous skin flora. The bacteria causing SSI reside deep in dermal sweat glands and hair follicles, untouched by traditional PSP. To eliminate these bacteria, antiseptics must diffuse deeper into the skin at concentrations above the minimum inhibitory concentration (MIC). We screened FDA-approved topical antiseptic products using a modified Kirby Bauer Assay to assess bacterial kill over time. We hypothesized that extended use of topical antiseptic products prior to surgery would kill deep-dwelling skin bacteria. We tested the extended use of these products on pig backs in conjunction with a CHG PSP to evaluate remaining bioburden. Methods:We determined the minimum inhibitory concentrations (MIC) for CHG and PVP-I against three common skin bacterial strains. We then took 6 mm biopsy punches of Tegaderm, Surgiclear, and Ioban and placed them on fresh bacterial lawns daily for 3 days. We measured the zones of inhibition (ZOI). Lastly, we applied the products to the backs of 4 Yorkshire pigs (n=4 products per test). After 48 h, we removed the products, performed a PSP- CHG scrub, and excised skin sections underneath the products. We homogenized the skin and quantified colony forming units (CFU)/g tissue. We analyzed the outcomes statistically using a mixed effects linear regression to determine significance.Results:The average MIC values for CHG and PVP-I were 2 and 2,000 ug/mL for Staphylococcus aureus, respectively. The average 24 h ZOIs for S. aureus were 7.9, 22.4, and 10.1 mm for Ioban, Tegaderm, and Surgiclear, respectively. The average log10 reduction for the CHG PSP, Ioban, Tegaderm, and Sugiclear were 1.87 ± 0.232, 1.65 ± 0.192, 1.69 ± 0.222, and 1.77 ± 0.316 CFU/cm2, respectively. The p values between the CHG PSP and Ioban, Tegarderm, and Surgiclear were 0.491, 0.572, and 0.746, respectively. Discussion:The benchtop data indicated adequate antiseptic diffusion and kill. In the porcine model, however; the presence of any of the products resulted in a statistically insignificant log reduction. Extended use of FDA-approved transdermal antiseptic products does not appear to decrease the skin’s bioburden. It appears that the products are not releasing high enough concentrations of the antiseptic to kill bacteria.

Authors: Jen Hansen. Mentors: Nicole Dib. Insitution: Southern Utah University. Toni Morrison’s contribution to Gothic horror with Beloved expands the tradition into the history of human enslavement, specifically in the context of American history. She reconceptualized ‘remembering’ as both the conscious awareness of the past and the literal reassembling of members of the body, and by extension the family and the home. Morrison coined the term “rememory” in reference to the intentional act of recollection performed by an entire community. The characters of the novel are haunted in several ways and each haunting is only exorcized or overcome through acts of communion, or rememory — many of which are symbolically religious even if not sanctioned as such. The main character is a woman named Sethe, who is haunted by the ghost of the daughter she murdered rather than allow to be taken as a slave. The ghost of Beloved represents the return of the repressed trauma of her death and the connection to Sethe’s previous life in captivity. In order to exorcize Beloved’s ghost and free themselves from her oppressive presence, Sethe and her living daughter, Denver, must re-member the broken family structure within their home, and rememory the traumatic past with the support of the community in order to heal. American Gothic traditions in literature have long been used to reflect on anxiety, discrimination, and disempowerment related to the Other. In this novel, Morrison uses that tradition to give shape to the culturally specific legacy of slavery in America. In this presentation I examine the novel’s Gothic elements and the ways the community plays the part of the exorcist as an essential advocate for the physical and emotional survival of Sethe and Denver.

Authors: Tate Thomas. Mentors: Alexander M Panin. Insitution: Utah Valley University. We wanted to see if accidentally creating mini black holes in high energy particle collisions posed a real threat to humanity. To do this, we calculated some properties of such a black hole, such as its life span, radius, density, and minimum energy required. We found that it is unlikely to exist, let alone destroy the planet. Furthermore, we calculated what would happen if it were to exist, finding that it would move through the Earth with little resistance and with a small amount of Earth matter absorbed. Depending on initial velocity, the black either quickly escapes Earth or would settle orbiting it with the orbit part of which passes via Earth. It is interesting that in a simplified model of Earth as of a sphere of uniform density, the inner part of the orbit of black hole is also elliptical (as the outer is) but not Keplerian - with Earth center not at the focus but at the center of another ellipse. In the case of small initial velocity when entire orbit is inside Earth, the period of such inner orbit is constant regardless of birth location and initial velocity of black hole. The goal of this presentation is to discuss the results of our calculations and to explore potential applications to our understanding of interaction of mini black holes with ordinary atomic matter.

Authors: Tage T Burnett, Jakob G Bates, Christopher R Dillon, Matthew R Jones. Mentors: Christopher R Dillon. Insitution: Brigham Young University. In recent years, modeling and simulation have become more prominent in solving heat transfer problems. The accuracy and predictive power of heat transfer simulations is limited by the quality of the thermal properties used within the model. Thus, one method for improving computational accuracy is measuring thermal properties more precisely. Additionally, increased precision of thermal properties benefits other aspects of engineering including design and analysis. This research focuses on quantifying approximation errors in the widely adopted flash method for measuring thermal diffusivity. The flash method leverages several approximations to make it simple and easy to use; however, these approximations do not reflect reality and introduce measurement errors. Understanding these errors is critical for developing high-precision thermal diffusivity measurement techniques.In the flash method, the top surface of a small, cylindrical disc of material is subjected to a short pulse from a laser or flash lamp and the time-dependent temperature at the opposite surface is recorded. The thermal diffusivity is calculated using those temperature measurements in combination with a mathematical model. The accuracy of the flash method depends upon the accuracy of the mathematical model. One common mathematical model is the Parker Model. This model assumes that all of the energy from the pulse is deposited in an infinitesimally thin layer at the surface of the material and negligible heat is lost to the environment. These assumptions simplify the model, making it easy to use, but introduce errors into the measured thermal diffusivity.Computational methods can quantify these inaccuracies. Factors including heat lost to the environment, the temporal profile of the laser pulse, and the spatial distribution of the deposited energy can be incorporated into heat transfer simulations. Higher fidelity mathematical models can also be developed to account for these complexities. This project includes these and other factors to make simulations as realistic as possible. Various mathematical models, such as the Parker Model and higher fidelity models, are then used to calculate the thermal diffusivity from the resulting time-dependent temperature profiles and their measurements are compared to the simulated material’s true thermal diffusivity. Repeating this process for several material types will allow the precision of the models to be analyzed for each case. This analysis will be summarized at the conclusion of this project, providing a framework for developing more precise thermal diffusivity measurement techniques.

Authors: Samuel Charles. Mentors: Marc Killpack. Insitution: Brigham Young University. Robots have an incredible potential to help humans in extreme or dangerous situations due to their significant and consistent durability, strength, endurance, replaceability, etc. However, humans and robots move very differently, leading to difficulties working intuitively with a robot partner when completing a task such as lifting a heavy object. We recently conducted studies in which human subjects moved a 60-lb table to several different positions in a room; we recorded force and torque data, along with many other aspects of the movement. In these studies of human-human co-manipulation, we noticed a trend during particularly difficult maneuvers; when lifting the table to high positions or acute angles, subjects switched their hand holds on the table’s handles. This was likely an easier method of holding the table, but it may have also communicated placement, stability, understanding, and strength to the other partner, leading to a smoother and more intuitive movement and experience overall. If this is the case, this data could be used to help a co-manipulation robot both effectively understand the subtle commands in human movement and intuitively communicate needed movement to the human partner. This is particularly useful in emergencies like natural disaster sites and war zones, in which immediate help is needed, but there is no time to troubleshoot an unclear or unintuitive robot.

Authors: Asmaa Alsharif. Mentors: Sayeed Sajal. Insitution: Utah Valley University. Ransomware is malicious software which restricts users from accessing their computer and personal data through encryption. Ransomware attacks target a variety of victims including individuals, organizations, businesses, and governments. Attackers take control of this sensitive data and hold it hostage until a ransom is paid. Whether or not ransom is paid, the attackers’ damage can be irreparable. It includes but is not limited to exposing personal information, identity theft, blackmail, permanent deletion or corruption of valuable data, and Distributed Denial-of-service (DDos). Moreover, the financial implications of ransomware attacks are substantial. Victims face not only the direct costs of ransom payments, but also the expenses associated with system restoration and the potential fines for data protection violations. Furthermore, an ethical dilemma emerges from the response to extortion, as victims must grapple with the moral implications of potentially supporting criminal activities by paying ransoms to recover their data. This raises questions about the broader responsibility of stakeholders in cybersecurity and their duty to protect data privacy. The first ransomware attack emerged in 1989 and since then, ransomware attackers have persisted as a cybersecurity threat, striking at the core of data privacy. This paper delves into the multifaceted impact of ransomware incidents on data security, current ransomware techniques and strategies, and the ethical dilemmas they raise.Because ransomware attackers are constantly evolving their methods, it is important to routinely review the current literature to fully understand the tactics and techniques used by these cybercriminals. This research paper will review, analyze, and synthesize the existing literature about ransomware. It is crucial for individuals and organizations to be proactive, understand the nature of the threat, and take precautions to protect themselves and their data. This study encourages further research and discourse on the multifaceted impact of ransomware attacks on data privacy and the pursuit for effective countermeasures.

Authors: Miranda Judson. Mentors: Mike Ashfield. Insitution: Utah State University. This research explores the relationship between Latter-Day Saint views and classical Christianity through the lens of the problem of evil. More specifically, this research looks at the implications both Augustine’s theory of evil and Latter-Day Saint theology have on each other and the impact that would occur should certain aspects be accepted by Latter-Day Saints. I argue that Latter-Day Saints should accept an interpretation of doctrine through the privation theory of evil in order to avoid potential threats to God’s goodness and the Plan of Happiness. Understanding Latter-Day Saint doctrine through this lens will better situate further research in the broader context of Christianity. Furthermore, accepting this theory will allow for a deeper understanding of the premortal existence and postmortal states. This deeper understanding is beneficial for both adherents to and researchers of Latter-Day Saint teachings. Finally, I argue this interpretation does not pose a threat to the doctrine of “opposition in all things.”

Authors: Matilda Gibb. Mentors: Ami Comeford. Insitution: Utah Tech University. Prior to 1930, cannabis was used frequently in therapeutic practices and was found in many over the counter health products. However, around this time what has been dubbed the “pot panic” began infecting American citizens. It was then the film Reefer Madness came onto the scene, exacerbating the public’s trepidation over the allegedly morally degrading effects cannabis inflicted. Putting melodrama at the forefront, the film exploits societal queasiness over sex, drugs, violent crime, and immigration to push its propagandist agenda. The fear mongering rhetoric and imagery used effectively poisoned the public and altered societal perceptions of medical and recreational cannabis use. The goal of this project is to analyze the rhetorical argument presented in the film and address its broader reach and effects. Lastly, I will argue that the message presented in Reefer Madness was not based on any logical argument; it was based on folklore.

Authors: Rainey Hughes, Avalon Marker, Elizabeth Bouwhuis, Yeshaswini Dudde, Bryan Dopp, Scot Carington, Jared Nelson. Mentors: Daniel Clark. Insitution: Weber State University. Antibiotic resistance is a pressing concern within the medical community as bacteria's resistance to antibiotics is escalating alongside the increased usage of antibiotics. According to the CDC, there are close to 2.8 million antibiotic resistant infections every year, with about 35,000 of them resulting in death. This issue has prompted antibiotic stewardship programs in clinics and hospitals to avoid adding to the list of resistant bacteria. Staphylococcus aureus, including the formidable methicillin-resistant S. aureus (MRSA) strain, poses a grave threat due to its antibiotic resistance. The challenges stemming from this resistance become even more formidable when these infecting bacteria assemble into biofilms. Biofilms are robust, adhesive layers composed of bacteria and their extracellular matrices of polysaccharides, proteins, and DNA. In clinical environments like hospitals, biofilms frequently develop on medical devices such as stents, catheters, and IV lines, as well as on metal and plastic surfaces of medical equipment. These biofilms exacerbate antibiotic treatments due to incomplete eradication; the most resilient bacteria persist after exposure. There is evidence indicating that bacteriophages, which are viruses that will a target particular species or strain of bacteria, have the ability to encode depolymerases. These depolymerases can identify biofilms, adhere to them, and subsequently break down extracellular polymeric substances. Furthermore, bacteriophages can produce lysins, which induce bacterial cell death through cellular lysis. These characteristics can potentially render the bacteria more susceptible to antibiotics. The use of bacteriophages can also be beneficial when it comes to the concern of opportunistic infections. Due to its selectivity to specific bacteria, it can attack the target hosts and leave the natural flora intact.In our research, we have induced biofilms in our bioreactor. With these biofilms we have been able to test different concentrations of multiple antibiotics, including Vancomycin, Oxacillin, and Carbenicillin in combination with phage K at different concentrations. Our research is aimed at showing a synergistic relationship between phage K and antibiotics, that will allow a subinhibitory concentration of both, in combination, to induce a complete kill and clearance. We have measured this by evaluating bacterial growth via absorbance measurements at 600nm in a Tecan plate reader. We have also measured biofilm clearance using the plate reader and measuring fluorescence at 630nm with a biofilm tablet assay. It was found that a subinhibitory concentration of antibiotic alone did not induce a complete kill and clearing, and that a subinhibitory concentration of phage alone did not induce a complete kill and clearing. However, once these concentrations were used in combination with each other, the complete clearing and killing of MRSA was achieved, and furthermore, was achieved with the antibiotic that the staphylococcus aureus is resistant to. Leading us to believe that we have found a renewed use for a currently ineffective defense mechanism.