Architecture

Authors: Dua Azhar, Alexander MacKenzie, Sophie Caron. Mentors: Sophie Caron. Insitution: University of Utah. The mushroom body of the Drosophila melanogaster is a structure in the brain that is necessary for learning, but much of how it functions remains unknown. In this model organism, D. melanogaster’s mushroom body neurons, known as Kenyon cells, and input projection neurons have connections that are random and biased—in which some projection neurons connect with Kenyon cells more than others—allowing the fly to potentially prioritize the learning of particular odors. I investigated the functional consequences and characterizations of these biases in order to understand the biological role they play for the fly using a theoretical and experimental approach. With a computational model of the D. melanogaster olfactory system, how biased connectivity to the mushroom body influences its ability to form associations with various odors and distinguish between similar odors was explored. Experimentally, the morphological features of olfactory circuits were characterized by low to high connectivity rates to the mushroom body, allowing us to see the unique features in these circuits that are beyond the different connectivity rates. Through a combination of immunohistochemistry and confocal microscopy, high-quality images were generated of these different neuronal olfactory circuits and their morphological qualities, such as the number and volume of boutons they project to the mushroom body. Altogether, these findings demonstrate how neural connectivities behind learning shape the representation space in D. melanogaster and impact its learning outcomes.

Authors: Alexa N Gormick, Adam M Zahm, Justin G English. Mentors: Justin G English. Insitution: University of Utah. Recent advancements in gene therapy have pushed towards the prevention and treatment of a diverse spectrum of disorders and diseases that are caused by misregulation of gene expression programs and their transcriptional regulators. However, the profoundness of the field means that much of the mechanisms and effects of regulation are unknown and understudied. Here, we explore the limits of flexible exogenous gene expression and its potential use in optimizing efficacy and specificity in gene therapy interventions while minimizing the possible associated risks. This is made possible by exploiting the Tet-On system of inducible transcriptional regulation, which allows the expression of any target gene to be reversibly, specifically, and differentially controlled. In this system, the tetracycline repressor (TetR) binds the tetracycline operator (TetO), impeding transcription of any downstream gene embedded by the researcher; tetracycline dosing causes TetR to adopt a new conformation that removes it from TetO, inducing gene expression on command (Das et al., 2016). Because of the diverse utility of this system, we are in pursuit of developing novel TetR-TetO orthologous pairs that do not interfere with this wild-type circuit and can be used to regulate gene expression in parallel. As a first step to generating TetR-TetO orthologs, we mapped the usage of TetO by TetR in a massively parallel reporter assay (MPRA) by engineering an extensive library of mutant TetOs and quantified the resulting range of TetR regulation through reporter gene expression. From this screen, we identified candidate TetO mutants to direct the evolution of the wild-type TetR towards complementary states to those TetO mutant sequences. Our preliminary findings indicate that the engineering of distinct synthetic expression cassettes based on the TetR-TetO operon is feasible. These novel tools may ultimately allow us to build a synthetic genetic circuit to model regulatory feedback loops that can help discover malfunctions in cell growth, reproduction, and cycling that can arise from genetic disorders and can lead to disease.1. Das, A. T., Tenenbaum, L., & Berkhout, B. (2016). Tet-On Systems For Doxycycline-inducible Gene Expression. Current Gene Therapy, 16(3), 156–167. https://doi.org/10.2174/1566523216666160524144041

Authors: Ives Hong, Grace Carsey, Tara Caplin, Hunter Mitchell, Peg Bird, Bridger Lisonbee, Maria Balaceanu, Dannelle Larsen-Rife. Mentors: Dannelle Larsen-Rife. Insitution: Utah Tech University. Attachment is fundamental to human development. The parent-child relationship impacts the physical and mental health of the child, particularly social development. The two attachment dimensions — attachment anxiety and attachment avoidance underlie the caregiver-child relationship in early childhood (Bowlby et al., 1973). Attachment anxiety and avoidance may change or persist throughout the life span. Major life transitions may influence attachment, however, people tend to revert to previous attachment trajectories after experiencing life transition (Fraley et al., 2021). Adverse childhood experiences (ACEs) are linked to attachment insecurity which may have notable outcomes in adult relationships (Ross et al., 2022; Synder et al., 2023). Individuals with attachment avoidance and anxiety may have difficulty maintaining existing connections. People with high attachment anxiety and inadequate social support experience poor health outcomes (Stanton & Campbell. 2014). Lack of social support predict post-traumatic stress and thoughts of suicide (Scoglio et al., 2023). Loneliness and social isolation are associated with insecure attachment (Spence et al., 2020). Loneliness is correlated with poor mental health ratings and symptoms, and even mortality (Holt-Lunstad et al., 2015; Jenkins et al., 2023). This study evaluates early attachment, health, and relationships. Approximately 200 adults will be recruited to complete the Experiences in Close Relationships-Revised questionnaire (Fraley et al., 2011), Adverse Childhood Experience Questionnaire (Felitti et al.,1998), the Social Support Questionnaire-Short Form (SSQ6; Sarason et al. 1987), and the three-Item Loneliness Scale (Russell et al., 1980 ).We expect attachment anxiety and avoidance will be positively correlated with loneliness and negatively correlated with social support, while ACEs moderate these associations. Examining how ACEs may interact with attachment avoidance and anxiety may prompt early intervention to improve the caregiver-child relationship.

Authors: Frankie Medina. Mentors: Joy McMurrin. Insitution: Utah Tech University. My research looks at the multifaceted extent of the lived experiences of Mexican-American women through the eyes of Chicana feminist's scholarships and social media content. The first research question considers the insights presented by Chicana feminists’ scholarship to delve into complex experiences. This will highlight their struggles, identities, and achievements. I aim to root around the fundamental theories and narratives that support the study of Mexican-American women.Second, I will examine the everyday experiences of Mexican-American women, and how it aligns with and/or deviates from the scholarship mentioned above. Through secondary research, I will examine common themes in the scholarship and compare them with the everyday experiences that I previously identified.Thirdly, I will research how contemporary Chicanas interact in formal and informal actions of protest that go against traditional norms and patriarchal systems. My research will focus on the gap between scholarly discourse and activism in real-life norms. I seek to present the different ways in which Mexican-American women delve into their own resilience and resistance in challenging existing obstacles. This qualitative research has three phases: first I will identify and synthesize common themes in Chicana feminist scholarship; second, I will code social media content, using both a priori and in vivo coding methods; third, I will write a thematic analysis of the contemporary Chicana experience. By reviewing these sources and data, I will provide an understanding of the experiences of Mexican-American women, their morale with scholarly discourse, and their roles in continued socio-cultural and political activities. The outcomes of this research hope to have regard for the complications around the Mexican-American female experience and their continuing efforts to challenge and change traditional norms and patriarchy

Authors: Lilliana Rogers. Mentors: Dannelle Larson-Rife. Insitution: Utah Tech University. One in five girls and one in twenty boys are victims of childhood sexual assault in the United States (Crimes, 2012). There is ample research on the effects and treatment of CSA on victims, however, a paucity of research on pedophiles and sexual offenders. In this social policy paper, the effects of childhood sexual abuse (CSA) on victims should use neuroscience research to prevent CSA. Furthermore, attachment in childhood is pertinent in developing healthy adult relationships, however, despite having a secure attachment to parents, children still face adverse effects of CSA in intimacy in adulthood (Barnum & Perrone-McGovern, 2017). Furthermore, adults exposed to CSA face a higher risk for mental health disorders, physical health problems, and substance abuse disorders, compared with adults who have not been exposed to CSA (Herder & Redner, 1991). Four main effects of concern are addressed in CSA victims: intimacy in adulthood, mental health risks, physical health risks, and substance abuse. These main points of concern illustrate the detrimental effects of CSA, and justify the need for change. Survivors are not the root cause of childhood sex abuse; perpetrators of sexual abuse against children are, leaving perpetrators who commit CSA at risk for reoffending. Incarceration is ineffective due to short sentencing and the child has already been sexually abused (Grady et al., 2015). In addition to ineffective reprimands, little research has been conducted on why and how pedophilia occurs. However, the limited research that has been conducted, is promising, but needs further funding and research to investigate the origins of pedophilia, how to treat it and how to prevent it. In addition, current pedophilia prevention efforts are noninclusive, inaccurate, and not targeted toward caregivers (Kenny & Wurtele, 2010; Grady et al., 2015; Finkelhor, 2009). Pedophilia is not addressed and treated, only the aftermath of CSA is. By analyzing these main concerns, we examine three points of intervention by addressing sexual offenders and pedophiles through the ineffectiveness of incarceration, the lack of funded research, neuroscientific research, and inadequate prevention methods. These points of intervention can be implemented and may reduce the risk of CSA so no child ever has to experience childhood sexual assault.

Authors: Reagan Bartholomew. Mentors: Dylan Hansen. Insitution: Utah Valley University. Unveiling the Challenges Faced by Deaf and Disabled Undocumented ImmigrantsThis paper shows the overlooked challenges confronted by a particularly vulnerable group—deaf and disabled undocumented immigrants. The motivation behind this study comes from the need to address the unique hardships experienced by this marginalized population. Our research employs a mixed-methods approach, combining participant observation, policy analysis and comparative analysis. Comprehensively exploring their experiences and shed light on their daily struggles.Our finding show that access to language resources is not just a matter of practicality but a matter of preserving their cognitive abilities and preventing language loss, particularly among young immigrants. We advocate for programs and specific policy changes that can help these individuals and their families with the skills they need to communicate effectively and integrate into society.This research significantly contributes to the fields of immigration studies, disability studies, and language acquisition. It underscores the urgency of allocating resources to address the specific communication needs of deaf and disabled undocumented immigrants, preserving their linguistic development and cognitive abilities.In conclusion, this paper seeks to raise awareness and advocate for more inclusive policies and resources to facilitate language acquisition for this vulnerable population. We look forward to presenting our research at UCUR 2024 and engaging in productive discussions about this pressing issue.

Authors: Avary Fielding. Mentors: John Salmon. Insitution: Brigham Young University. Human-robot co-manipulation is a field of study that explores humans and robots collaboratively moving objects in various applications, including areas such as search and rescue or disaster response. The focus of this particular research is the coordination of a group of 2-3 human participants to maneuver a 55-lb table and execute specific tasks, in order to draw insights on effective strategies for humans-robots teams. Within each group, a leader was equipped with a virtual reality (VR) headset, providing them with a visual representation of the end goal. In contrast, one or multiple followers, who were unable to see the desired final position, had the responsibility of following the leader to complete the task. Data pertaining to forces, torques, and position was recorded for several iterations of 18 unique table movements to investigate group strategies and learning over time. One specific maneuver involving diagonal translation in the transverse plane (xy, with +y being to the left of the leader) became of special interest and led to the formation of two key hypotheses surrounding the evolution of human coordination strategies. First, it was hypothesized that participants would initially approach the task by translating forwards (in the x direction) and then sideways (in the y direction), before potentially optimizing their strategy in subsequent trials. Second, it was anticipated that, after successfully completing the task twice, participants would adapt to a more efficient method, involving direct diagonal translation. This research aims to answer whether the transition from sequential translations to diagonal movement is a learned behavior, developed over time as groups become more adept at the maneuver. Understanding how humans naturally tend to optimize large object manipulation can be invaluable in the realm of human-robot co-manipulation, as it provides a point of reference on which to base robot behavior, ultimately improving performance and efficiency in various co-manipulation scenarios.

Authors: Rachel Krupnek. Mentors: Jie Liu, Sazib Hasan, Vinodh Chellamuthu. Insitution: Utah Tech University. Many groups are interested in potential market indicators because more than 60% of adults in the United States have investments in the stock market. Extreme stock trading volumes can be an important indicator of unusual market events, including those that precede market crashes. Several studies utilized Extreme Value Theory (EVT) and the Generalized Pareto Distribution (GPD) to examine and model the behavior of these extreme volumes. In particular, various estimation techniques are explored within the GPD framework to best fit the stock trading volume data. The goal of this study is to utilize mathematical approaches in economics. Our results have implications in both mathematical and economic fields, providing benefits by enhancing our ability to analyze and prepare for extreme market occurrences.

Authors: Heather Smith. Mentors: Vinodh Chellamuthu, Jie Liu, MD Sazib Hasan. Insitution: Utah Tech University. The invasive species Japanese Beetle (Popillia Japonica) poses significant ecological and economic challenges in the United States, with an annual expenditure exceeding $300 million on damage repair and control efforts. The beetle's life cycle predominates as grubs in turf from late August to April, suggesting a strategic window for control interventions. We developed an individual based model of the Japanese Beetle life cycle, utilizing predator-prey models, to demonstrate the effectiveness of various control methods. Our findings would suggest that ideal timing of grub treatments within the diapause stage markedly reduces beetle populations and is a cost-effective control method. The results of this model can inform land management decisions in controlling Japanese Beetles.

Authors: Ben Martinez, Virginia Merrill. Mentors: Muhammed Yildiz. Insitution: Utah Tech University. This study investigates the multifaceted dimensions of food insecurity among students at Utah Tech University, drawing from the American College Health Association National College Health Assessment survey conducted in Spring 2021, comprising a sample size of 347 students. Shockingly, 46.7% experienced food insecurity in the past 30 days, with certain demographics disproportionately affected—specifically, male, nonwhite, non-heterosexual, disabled, athlete, and single students. We also found associations between food insecurity and deteriorating health and well-being. Those affected reported significantly lower overall health and well-being levels, alongside heightened instances of suicidality, stress, and psychological distress. This research underlines the urgency to address food insecurity, particularly among at-risk demographic groups, and emphasizes the critical need for targeted interventions and support mechanisms. It highlights the concerning link between food access and mental health and advocates for inclusive strategies to address disparities among students. Implementing support systems to mitigate food insecurity's adverse impacts is crucial in fostering an environment conducive to the academic success and overall well-being of all students at Utah Tech University.

Authors: Soren Pearce. Mentors: Jacob Hickman. Insitution: Brigham Young University. Conversations about conspiracy theories have become prevalent in contemporary Western society, reaching through all levels of private, academic, and governmental discourse. Part of this discourse revolves around the question of what exactly conspiracy theories are and how they occur within a population; much of the recent academic treatment of conspiracy theories identifies them as a kind of propaganda whose purpose is to promote particular political agendas, especially those with apocalyptic concerns (Cassam 2019). While conspiracy theories certainly have been and continue to be used to further certain political aims, this understanding of them as totally propaganda provides only a narrow insight that fails to capture the scope of how conspiracy theories occur in the real world and how they are experienced by the people who believe in them. Philosophy and political theory can only be so informative, and they lack an ethnographic perspective to instruct on the lived reality of conspiracy theories (Hickman & Webster 2018). During my fieldwork in Belfast, Northern Ireland, I conducted ethnographic research with a group of people who could easily and accurately be labeled conspiracy theorists; my experiences with them provide insight into how conspiracy theories actually operate in the lives of living people. Contrary to popular claims, conspiracy theories—especially those that deal with the end of the world as we know it—are not experienced as primarily political phenomena. Instead, they are experienced as religious truths, and the millenarian activism that often surrounds them is enacted because of a conviction of personal obligation to the truth. Framing conspiracy theories as mere propaganda or dismissing them as the effects of cognitive dissonance incorrectly discounts the empirical reality of these beliefs for the people who have them.

Authors: Danielle Black. Mentors: Chris Anderson. Insitution: Utah Valley University. Attention Deficit Hyperactivity Disorder (ADHD) is a common psychiatric disorder diagnosed in children, characterized by impulsivity, inattention, and hyperactivity. It is frequently co-morbid with eating disorders, primarily bulimia nervosa (BN) and binge-eating disorder (BED). Impulsivity is an important factor in increasing the risk of binge-eating and subsequent feelings of guilt, which may prompt purging behaviors. This often manifests early in childhood as loss of control while eating and can indicate future development of an eating disorder. The current project aimed to assess the link between ADHD symptoms and disordered eating in Utah Valley University alumni. After obtaining IRB approval, 265 alumni responded to an email survey containing nineteen questions regarding ADHD symptoms and three items related to disordered eating. Pearson correlations revealed a significant association between ADHD symptoms and binging (r=.22, p <.01) as well as guilt about eating (r=.17, p <.01). Limitations of the study include the absence of a clinical ADHD diagnoses, relying instead on self-report, and the homogeneous sample, restricting its generalizability. The study was bolstered by its comprehensive coverage of ADHD symptoms and an adequately large sample size to detect statistical significance. This study provides valuable information for those suffering from eating disorders and the clinicians that treat them. Future research could assess the interplay between treating ADHD and reducing the risk of eating disorders. Notably, purging and ADHD symptoms were not significantly correlated, and future research could further explore that relationship. In conclusion, the relationship between binge eating and ADHD symptoms should be acknowledged by clinicians.

Authors: Cari Monson, Julie Pynn. Mentors: Julie Pynn. Insitution: Southern Utah University. Background music refers to music that is played while the listener’s attention is focused on another task (Radocy & Boyle, 1988). Research suggests that the effect of background music on performance during a cognitive task showed improvements in episodic memory. Music activates the limbic system which is involved in controlling memory(e.g., Blood et al., 1999). The purpose of this study is to predict the relationship between music and performance on a cognitive task. It is hypothesized that students who listen to white noise while studying a text will recall more information, than those listening to classical music or pop music. In particular, the lyrics in pop music will be especially distracting(Cheah, 2022). Studying the relationship between music and performance on a cognitive task has implications for understanding memory. Results are forth coming

Authors: Ivelynn Noel. Mentors: Julie Johnson Pynn. Insitution: Southern Utah University. High levels of sexual satisfaction have been correlated with higher levels of marriage satisfaction (Litzinger & Gordon, 2005), relationship satisfaction (Santilla et al., 2008), and mental health and general well-being (Brody & Costa, 2009). While we know that sex frequency and frequency of orgasm affect sexual satisfaction (Barrientos & Paez, 2006), we also need to explore nonsexual factors that affect sexual satisfaction. The existing literature of the effects of religiosity on sexual satisfaction is contradictory, and may have mediating factors such as sex guilt or marital status (Hackathorn et al., 2016). The proposed study aims to examine the effects of religious identity and marital status on sexual satisfaction by measuring sexual-spiritual integration. We predict that unmarried individuals will score higher than married individuals, which indicates a lower sexual-spiritual integration. The findings of this study will add clarity to the convoluted findings in the existing literature , and will help identify nonsexual factors that affect sexual satisfaction. The findings of the study will also provide insight that may help healthcare workers, pastoral counselors , and therapists to better service their clients. Results are forthcoming.

Authors: Vanessa Lozano. Mentors: April Reber. Insitution: Brigham Young University. According to the Center for Immigration Studies, “the total foreign-born or immigrant population in the U.S. hit 47.9 million in September 2022- a record high in American history. When non-English immigrant families arrive in the United States they face the challenges of new customs, rights, and practices in their new home. In the United States various NGOs, government aids, and non-profit organizations are available to immigrants to help them navigate these challenges. Evaluations about the efficacy of these resources should be considered with the increasing number of immigrants in the United States. In this research, we focus on one of these resources, a mental well-being support group geared to immigrants but attended mostly by Latina women. The support group is currently held at a non-profit community center the South Franklin Community Center (SFCC) in Provo, UT, and sponsored by the organization Inciativa Latina para el Bienestar Emocional [Latino Initiative for Emotional Well-being]. To consider the efficacy of this support group in this research we explore the following questions 1) How does support get produced in the context of this support group at the SFCC? 2) Does (and if so, how does) participating in these support groups expand the agency of participants? (By agency, I refer to the capacity or condition of someone to have control or power to act).

Authors: Cole Murphy, Andrew Blazzard, Austin Barney. Mentors: Patrick Steffen. Insitution: Brigham Young University. BackgroundHigher levels of social media use (SMU) have demonstrated associations with higher levels of self-reported stress. However, the association between SMU and physiological markers of stress, such as heart rate variability (HRV), is less understood. We hypothesize that increased time spent each day on social media will be associated with decreased baseline HRV, but only for individuals who report high rates of stress. We also hypothesize that time spent on social media will be associated with decreased baseline HRV for individuals with higher levels of neuroticism. When considered together, we hypothesize the largest association between SMU and baseline HRV for individuals with higher levels of both stress and neuroticism.MethodsUsing a sample of 165 undergraduate students, we measured baseline heart rate variability with a 3-lead ECG. We determined the average SMU using the Social Media Use Questionnaire (SMUQ). We also ascertained self-reported stress levels using the Depression, Anxiety, and Stress Scale (DASS), and levels of neuroticism using the IPIP NEO Neuroticism Extraversion Openness - PR (IPIP-NEO-120). We will use multivariate regression for our analysis.ResultsResults are undergoing analysis. ConclusionsWhile the use of social media by itself may not have a clear direct association with HRV, it is important to consider the effects of social media use on people with a high emotional state of stress and/or high levels of neuroticism. As public policy continues to be developed for social media, it is important to consider how people with higher tendencies to become stressed and those with higher levels of neuroticism can be affected by social media use if unregulated.

Authors: Parker McKasson, Hannah Hornberger, Sydnee Bond, Olivia Heller, Josh Marchant. Mentors: Patrick Steffen. Insitution: Brigham Young University. BackgroundIntrinsic religiosity is a deeply rooted connection to one's faith. Individuals with high intrinsic religiosity find purpose and meaning through their spiritual connections. Extrinsic religiosity is primarily driven by social or other superficial factors. Individuals with high extrinsic religiosity may be more inclined to participate in religious activities and communities without having a deep connection to their faith. Intrinsic religiosity has demonstrated associations with lower self-reported stress, however, associations between intrinsic/extrinsic religiosity and baseline heart rate variability (HRV), a proxy measure of the parasympathetic nervous system, have not been studied. Such research has the ability to explain how the complex relationship between religiosity and stress affects overall well-being. We hypothesize that higher self-reported stress will be associated with lower baseline HRV, but intrinsic religiosity will serve as a buffer, such that stress will have a weaker influence on baseline HRV among individuals who are more intrinsically religious. We predict that extrinsic religiosity will have no influence on the relationship between stress and HRV. MethodsA survey and biofeedback study were conducted on a sample of 165 college students. We used the Depression, Anxiety, and Stress Scale (DASS) and Intrinsic/Extrinsic Religiosity Scale (IE/R), as well as measured baseline heart rate variability (HRV) using a 3 lead ECG. We will analyze the impacts of stress on HRV across people with varying levels of intrinsic/extrinsic religiosity through a multivariate regression model.ConclusionsReligiosity is not often viewed as a direct contributor to health and wellness, however, when viewed as a protective barrier against stress, intrinsic religiosity could play an important role in an individual’s stress response and wellbeing. In the presence of stressors, we expect intrinsic religiosity to be related to healthier parasympathetic functioning as measured through HRV.

Authors: Vanessa Tuttle. Mentors: Liz McGuire. Insitution: Brigham Young University. Despite significant strides in global gender equality, women remain underrepresented in leadership roles, prompting investigation into public perceptions of women’s leadership. Our research delves into the often-overlooked aspect of female-to-female interactions and their impact on women's self-perception as leaders. We aim to identify the voices that most influence women's beliefs about their leadership abilities, contributing to the broader discourse on gender parity in leadership. Drawing on historical and cross-cultural perspectives, we theorize that women, historically designated as primary caregivers and reproducers of society, play a pivotal role in shaping individuals' beliefs. This designated role may lead women to internalize societal norms that undervalue their leadership capabilities outside the home. We examine the potential impact of empowered female role models on women's confidence in leadership roles. We employ a lab-in-field experiment conducted in Kuala Lumpur, Malaysia, and Arusha and Dar es Salaam, Tanzania. Participants are assigned to groups with varying gender compositions, engaging in a task where success is dependent upon the leader, followed by a post-treatment survey evaluating their experience, leader, and perceptions of female leadership. Through this experiment, we contribute empirical evidence to the ongoing discussion on gender disparities in leadership and challenge existing theories, providing valuable insights into the complex dynamics that contribute to the confidence gap between men and women in leadership roles. Our preliminary findings from our ongoing research may have implications for strategies aimed at fostering gender equality in leadership, encouraging a more nuanced understanding of the factors influencing women as leaders.