Presenter: Shoma Mukai
Authors: Shoma Mukai, Nathan Werner
Faculty Advisor: Nathan Werner
Institution: Southern Utah University
Many alkenes are used as starting materials for the synthesis of detergents, drugs, and pesticides. The palladium-catalyzed Suzuki-Miyaura cross-coupling reaction is an efficient method to synthesize trans-alkenes of specific stereochemistry. We first studied the synthesis of alkyl substituted alkenyl boranes by 9-BBN-catalyzed hydroboration reaction. Then, we studied the ability of alkyl substituted alkenyl boranes to participate in the Suzuki-Miyaura cross-coupling reaction. Here we present our research on the synthesis of alkyl substituted trans-alkenes from alkynes by a two-step hydroboration and cross-coupling reaction.