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Fine Arts

Feminine versus Freakish: The Silence of the Lambs and TERF Rhetoric

March 21, 2024 12:00 AM
Authors: Kenna Johnson. Mentors: Nicole Dib. Insitution: Southern Utah University. My paper is an interpretative analysis of Thomas Harris’ 1988 novel The Silence of the Lambs as analyzed through the lens of feminist film critic Laura Mulvey’s concept of the masculinization of spectators. In her essay collection Visual and Other Pleasures, Mulvey discusses how cinema, as a traditional medium, has misogynistic, voyeuristic characteristics. Through camera angles and editing, the audience is subconsciously led to identify with the protagonist (who is typically male). As a result, we, the audience, follow his gaze to his object of desire: the woman. This phenomenon she deems the masculinization of spectators. In my paper, I have applied Mulvey’s theory to Harris’ novel and concluded that the masculinization of spectators is, in fact, subverted in The Silence of the Lambs. Here, the audience identifies with Agent Clarice Starling, a young FBI trainee. We follow her gaze to the man she has been tasked with hunting: Jame Gumb, who is referred to colloquially throughout the novel as “Buffalo Bill.” Throughout my paper, I analyze the stark differences in characterization between these two. While Starling is depicted as a pillar of feminine strength, Gumb, a male to female transgender character, is depicted as gaudy and grotesque. In comparing the notable differences in characterization, I determine these characters to serve as each other’s foils. Having been denied as a candidate for gender reassignment surgery, he creates a ‘girl suit’ out of his victims’ skins as an attempt to pass as a woman. Gumb’s atrocities paint the transgender population in a monstrous light; Starling’s actions, conversely, portray her as fiercely independent, and a hero for the feminist cause. Drawing from this analysis, I argue that The Silence of the Lambs is a stark support for the trans-exclusionary radical feminism, or TERF, movement. Through an in-depth analysis of the literary symbols present in the novel in conjunction with the two main characters’ characterization, I determine that TERF rhetoric beats strongly underneath the novel’s surface feminism.

Bacterial Separation by poly-Dopamine Coated Magnetic Nanoparticles

March 21, 2024 12:00 AM
Authors: Camille Bryner, Alyson Camacho, Bowen J Houser. Mentors: William G Pitt. Insitution: Brigham Young University. In an attempt to combat a growing number of nosocomial infections related to medical devices, many studies have investigated the effect of polydopamine (pDA) coated surfaces on biofilm formation and found them to have antibacterial and anti-adhesive properties. However, we discovered that pDA coated magnetic nanoparticles (MNPs) display strong attractive interactions with many, but not all, species of bacteria. Fe3O4 MNPs were prepared using sodium acetate, ethylene glycol, and iron (III) chloride hexahydrate solutions and characterized by a variety of methods. XRD data confirmed a magnetite pattern characteristic of Fe3O4, then TEM characterization of MNP samples showed successful pDA coating onto iron oxide particles. Bacterial capture efficiencies (CE) by pDA-MNPs for 8 strains of bacteria were measured by optical turbidity and plate counts. We have found that CE is a function of exposure time to and concentration of MNPS; thus some experiments were done with constant exposure time and variable MNP concentration and others were done at variable exposure times and constant MNP concentrations. Additionally, these pDA-MNPs exhibit extremely efficient adhesion to some bacteria such as Staphylococcus epidermidis (S. epidermidis) while being ineffective at capturing some strains of Esherichia coli (E. coli). We propose that such capture ability of pDA-coated MNPs can be employed for detection and identification of bacteria in hospitals and for food science quality control.

Bloom's and SOLO: A Comparison of Educational Taxonomies

March 21, 2024 12:00 AM
Authors: Spenser A Clark. Mentors: Acacia Overono. Insitution: Utah Valley University. It is not uncommon for a college student to see a list of learning objectives when skimming through a syllabus for a program or course. The goal of learning objectives is to set reasonable expectations for student learning and guide their study, as well as providing a framework for the development of teaching practices and assessment. Part of the inception of learning objectives as a means of organizing teaching and assessment in the classroom may be attributable to the Taxonomy of Educational Objectives, more commonly referred to as Bloom's Taxonomy. Another taxonomy similar to Bloom's, but much less well known, is the Structure of Observed Learning Outcome (SOLO) taxonomy. Bloom’s taxonomy organizes learning objectives into six categories: Remember, Understand, Apply, Analyze, Evaluate, and Create. The categories are structured as a cumulative hierarchy in which mastery of each level is assumed necessary for progressing to the next. The structure of Bloom’s is not derived from any specific learning theory, but a categorization of pre-existing learning objectives. Bloom’s therefore suffers from a lack of a strong theoretical foundation and may not accurately reflect how learning actually occurs. Additionally, although Bloom’s has been widely employed in the context of educational assessment, research has shown that it suffers from low interrater reliability and is inconsistent between educational contexts such as courses and topics. Unlike Bloom’s, SOLO is based upon Piaget’s Stage Development theory and categorizes learning into five distinct stages: Prestructural, Unistructural, Multistructrual, Relational, and Extended Abstract. SOLO does not suggest that learning is unidirectional or hierarchical. It also acknowledges internal cognitive processes rather than focusing solely on observable behaviors. Although very little research has investigated its reliability, it could be an attractive alternative to Bloom’s because it may more accurately reflect how learning occurs. The present work reviews the development and implementation of these two models and compares them.

Digging the Rabbit Hole: Jean Baudrillard and Mike Rothschild's "The Storm is Upon Us"

March 21, 2024 12:00 AM
Authors: Ezra Stein. Mentors: Nicole Dib. Insitution: Southern Utah University. In Simulacra and Simulation (1981), Jean Baudrillard lays out for stages through which a sign (an image or other representation of reality) becomes a simulacrum (a sign with no basis in reality). I argue that the followers of the Qanon conspiracy movement, as detailed in Mike Rothschild’s "The Storm is Upon Us" (2021), follow these four stages in their radicalization into the conspiracy. The first stage outlined by Baudrillard is when the image is a basic reflection of reality itself. We see this stage when Rothschild discusses how QAnon believers discuss the CIA. Adherents of QAnon will often point to the declassified MKULTRA documents released by the CIA for credibility, as this is something that was proven to have actually happened, the sign being a representation of actual reality. The second of Baudrillard’s stages is when a sign takes something from reality and twists and distorts it into something different than what it originally represented. An example of this in "The Storm is Upon Us" is seen in the way Q believers talk about adrenochrome, which is a real but harmless chemical compound, as an elixir of youth used by the elite. Stage three is when a sign claims to be based in reality but is actually based on nothing at all. The originator of QAnon, the man who goes by “Q,” fits within this stage. Rothschild lays out Q’s origins as an anonymous poster on the website 4chan who claimed to high-level military clearance. Q’s claims were supposedly based on real-life military intel, but were actually made up by an anonymous stranger on the internet. The fourth and final of Baudrillard’s stages is the simulacrum. This is when signs do not reflect anything in reality, but instead are based on other signs. The Storm is Upon Us shows that many QAnon beliefs, both major and minor, are based in pre-existing conspiracy theories like blood libel, flat earth, and global cabals that secretly control the world. Those who are completely indoctrinated into QAnon hold these beliefs that are based on other beliefs and are therefore existing in Baudrillard’s fourth stage of the precession of simulacra. My presentation will examine these four stages and demonstrate the overlap between this critical theory and the contemporary conspiracy movement that is taking up a considerable space in the American cultural imaginary.

Chronic obstructive pulmonary disorder remote patient monitoring using spirometry: a systematic review

March 21, 2024 12:00 AM
Authors: Joseph Nielson, Ben Schooley. Mentors: Ben Schooley. Insitution: Brigham Young University. Chronic obstructive pulmonary disorder (COPD) affects an estimated 30 million Americans and is the third leading cause of death worldwide. A recent effort to curb deaths and hospitalizations involves remote patient monitoring (RPM). Of all possible monitoring parameters, spirometry presents itself as potentially accurate and helpful, but the exact effect and its size remain to be described. A systematic literature review is being performed to describe the current state and future opportunities in RPM systems that use remote spirometry for COPD patients. Only studies that specifically mention the use remote spirometry for monitoring COPD patients were included. The databases PubMed, Web of Science, Scopus, and EBSCO were searched in July and August 2023. Studies are being synthesized by tabulating the study sizes and designs, technological parameters, and interesting findings. Twenty-nine studies have been included spanning feasibility and pilot studies as well as one randomized clinical trial. Remote spirometry for COPD patients has generally been shown to be feasible. Many studies present systems in early stages of development that have yet to be tested thoroughly in large trials. It may be necessary to involve remote spirometry in more large-scale trials soon. Future studies could confirm the degree to which spirometry adds helpful information for monitoring COPD patients.

Understanding the Effect of Printing Parameters and Prewetting on Binder Jetting Continuous Line Formation

March 21, 2024 12:00 AM
Authors: A. Kalani Brubaker. Mentors: Nathan Crane. Insitution: Brigham Young University. Binder Jetting is an exciting form of Additive Manufacturing in which a binding agent is selectively deposited on layers of powder to bind the powder together and create a 3D printed part. It is notable for its wide range of materials, energy efficiency, and built-in supports. Much research has been done on how to achieve desirable properties of binder-jetted parts and post-processing, but the fundamental principles of binder-powder interaction and the effects of changing printing parameters are still not fully understood. This research aims to increase that understanding. Each binder-jetted part begins by depositing individual binder droplets in a straight line, and the binder-powder droplets coalesce to form a single line. Adjacent lines are then printed to form a cross-section of the part, the next layer of powder is applied, and the process continues until a 3D part is printed. If the spacing between the droplets is too large or the inter-arrival time too short, the droplets form spheres on the surface of the powder (a phenomenon called balling), and a continuous line is not formed. This research determines how continuous line formation is affected by droplet spacing, inter-arrival time, and controlled misting of the powder bed prior to printing. To examine the effects of these parameters, lines were printed in dry and prewetted powder beds while varying the spacing and inter-arrival time between droplets. The beds were then examined using an optical microscope to determine whether continuous lines were formed. The results were recorded on a graph of inter-arrival time versus droplet spacing, and the “boundary line” for successful line formation was found for each bed. The results showed that the boundary on the prewetted data exhibited a different relationship than dry powder beds, suggesting that a different binder-powder principle may dominate after prewetting. The prewetting also shifted the boundary upwards, making it possible to form continuous lines at higher droplet spacings and shorter inter-arrival times. This increased ability to form continuous lines has the potential to significantly increase the throughput of binder-jetted parts.

Musical Manipulation: Controlling Memory And Emotions Through Auditory Processing

March 21, 2024 12:00 AM
Authors: Kaerli Ringle. Mentors: Johnathan Chidester. Insitution: Southern Utah University. This presentation will discuss the way that music affects memory retention, memory recall, and how it can influence the memory of moments, moods, and emotions. The Public Broadcasting System produced an educational video about how listening to music boosts learning and memory. Research from Harvard noted that while neuro-imaging a patient, singing will help a patient during recovery with a brain injury or a stroke. This results because the left-brain region is majorly responsible for our speech function. Researchers also noted that because singing takes place in the right hemisphere, recovering stroke, Dementia and Alzheimer’s patients are able to regain their speech through singing and eventually being able to transition back into speaking. Having knowledge of how music affects the brain can help build great study habits and empower people to retain new information, recall old information, and have influence over their and other people’s emotions. This is important because music is around us all of the time, whether it is walking through the grocery store or playing through earbuds while studying, and if it has such power to influence these things, then why not use it to the fullest of its potential?

Constant pressure untethered soft robotics: an adaptable solution to the limitations of soft robots

March 21, 2024 12:00 AM
Authors: James Wade, Chris Paul. Mentors: Nathan Usevitch. Insitution: Brigham Young University. Soft Robotics offer significant advantages when completing certain tasks compared to other robots and methods. Compliance, adaptability, and energy efficiency are a few of the major advantages. On the moon, where safety, volume and versatility are of high importance, soft robotics may find an innovative niche. NASA’s BIG Idea Challenge for 2024 incentivizes creating new innovative soft robot designs. Our research group is building our facility mentor, Nathan Usevitch’s, work at Stanford University. Doctor Usevitch and his cohort developed an octahedral, inflated robot composed of multiple tubes folded into triangular shapes in a truss-like structure. Each triangle consisted of a long inflatable tube and 3 motorized modules at the nodes of the triangle. The motorized nodes (consisting of a DC motor and rollers) roll along the length of the tube, lengthening one edge of the triangle while shortening the other. By attaching multiple triangles to each other in geometric shapes, flexible structures are created that can adapt their shape to the desired need. Because this system has a constant inflated volume, no external air compressor is necessary, allowing for untethered movement. The bulk of the mechanical work is performed by electric motors, providing a higher energy efficiency than a system of repeated inflation. Furthermore, this design is compactly stored when deflated, optimal for transport into space.To build on this design and optimize it for use on the moon, our research group will make the following changes and improvements:- Developing the physical prototype. This will enable robust and dynamic movement and the support of large loads- Develop a simulation tool that allows us to explore different configurations of the robot for different tasks- Develop a joint system that allows an astronaut to quickly reconfigure the triangles into different structures based on the required task - Develop a control approach that accounts for the underdamped dynamics of large inflatable structuresThrough our research, we hope to expand the possibilities of soft robotics. We are synthesizing the advantages of traditional robotics (robustness, untethered motion) with the unique strengths of soft robotics (flexibility, adaptability, cost efficiency).

The Gender Pay Gap in FinTech: An Analysis of Womens Compensation in the Industry

March 21, 2024 12:00 AM
Authors: Rachel Bi, Chong Meng. Mentors: Rachel Bi. Insitution: Utah Valley University. The full proposal is available upon request. This research project is sponsored by the Bonnie Ballif-Spanvill Endowed Fellowship, which provides $10,000 in funding.Abstract:Over the past decade, the financial technology (FinTech) industry has experienced remarkable growth and innovation, with new products and services designed to meet the evolving needs of consumers. This rapidly expanding force is challenging and disrupting traditional financial industries in terms of product innovation, customer satisfaction, and employer demand in the labor market. In fact, global FinTech investments have soared from less than $2 billion to an impressive $142 billion in 2021, and this upward trend is expected to continue (Balyuk, Berger, and Hackney, 2020). While previous studies have focused on the impact of FinTech on income inequality, little is known about the potential of this digital technology to address gender inequality (Loko and Yang, 2022).This proposal seeks to address a specific aspect of gender inequality: the gender pay gap in finance. This term refers to the wage disparity between male and female executives in the industry. Our objective is to analyze women's compensation within the FinTech sector, identify factors contributing to the gender pay gap, and develop recommendations to address this issue. Specifically, we have the following hypotheses:H1: Gender pay gaps among executives should shrink in the FinTech industry.Public FinTech firms are typically younger and smaller than other publicly traded companies. Because managers in smaller firms are generally less risk-averse and have a stronger preference for taking risks, we hypothesize that the gender pay gap between female and male executives could widen due to differences in risk-aversion.H1a: Gender pay gaps among executives should enlarge in the FinTech industry.Our second hypothesis centers on comparing gender pay gaps in the pre- and post-initial public offering (IPO) stages of the same company. The public market is widely recognized as crucial in overseeing and limiting managers' pursuit of risk (Asker, Farre-Mensa, and Ljungqvist, 2015). If executives' risk aversion changes with access to the public market, we anticipate that gender pay gaps will decrease following IPOs. Therefore, H2: Gender pay gaps among executives should shrink in FinTech firms after their initial public offerings. Institutional investors in the public market can shape the internal corporate governance structure (Dasgupta, Fos, and Sautner, 2021). We anticipate that board diversity, measured by the percentage of female executives on the board, will increase after IPOs. Consequently, we predict that the changes in gender pay gaps between the pre-IPO and post-IPO periods will be more noticeable when the board is less diverse prior to IPOs. H2a: The decrease in gender pay gaps should be more pronounced when the board of a Fintech firm is less diversified before IPOs.

Pollen DNA Metabarcoding to Analyze the Effect of Formic Acid Treatment on Foraging Behaviors of Apis mellifera

March 21, 2024 12:00 AM
Authors: Claudia Wiese, Josh Steffen, Heather Briggs, Rodolfo Probst. Mentors: Josh Steffen. Insitution: University of Utah. Evaluating effect of formic acid treatment on foraging behaviors of Apis mellifera through pollen DNA metabarcoding using the MinION deviceBees play a vital role in maintaining the health and productivity of terrestrial ecosystems by providing pollination to many of the world’s plants. In recent decades, many bee species, including Apis mellifera (European honeybee), have experienced worldwide population declines.Varroa destructor, an external parasite, is one of the leading causes of honeybee population declines, as they are the primary cause of colony collapse disorder.Various methods exist to control the impact of V. destructor, including Formic Acid (FA) treatment, a well-documented solution to reducing V. destructor numbers. Yet, despite clearly established evidence that A. mellifera behaviors are very sensitive to changes in their hive environment, very few studies have looked at the effect of FA on honeybee foraging behavior. DNA metabarcoding is a powerful tool allowing ecologists to quantitatively assess differences in diet within species without the need for extensive knowledge of pollen taxonomy or complicated fieldwork experiments.In this study, A. mellifera hives (n=7) were split into control (n=3) and treatment groups (n=4). Pollen samples were collected from all hives before, during, and after FA treatment to compare if FA application impacted the foraging patterns of the bees in the treated colonies as compared to the control group. To compare foraging patterns between the treatments, we performed metabarcoding using the trnL (UAA) chloroplast intronic region, commonly used to barcode plant species. Amplicons were subsequently sequenced with a portable sequencer (ONT MinION Mk1C). Basecalling, quality check, demultiplexing, and filtering of the data were conducted with Guppy and Medaka. Obtained sequences (n=120 reads) were compared to a reference database with BLAST to determine the sequence identity of visited plants. With this information, we plan to compare absolute foraging numbers, species, and related ratios between control and experimental hives. Most sequences were assigned with a high percentage identity to a sample database (>89%), Although certain species (e.g., Malus sylvestris [European crab apple] and Prunus avium [wild cherry]) were probably visited by all hives, our preliminary findings show that pollen loads differ between control and experimental conditions, indicating a variation in floral visitation.These results suggest that FA treatment, while effective at controlling V. destructor, may impact honeybee foraging patterns. Further research is needed to understand if this behavioral change is detrimental to the health of the colony, and the consequences of variation in floral visitation to pollination networks.

What Makes a Legend: Characterization’s Role in Arthurian Universality

March 21, 2024 12:00 AM
Authors: Em Hart. Mentors: Nicole Dib. Insitution: Southern Utah University. The legend of King Arthur has withstood the test of time unlike any other work of literature. Not only is a tale originating from a post-Roman Britain still known today, it is influential and pervasive, impacting the building blocks, themes, and motifs of contemporary stories in genres ranging from fantasy to superheroes to propaganda pieces. Given the legend’s undeniable influence, it sparks the question of what characteristics have allowed this tale to transcend the standard literary lifetime. One theory attributes the legend’s universality to the romantic narrative structure that it gained during the French Vulgate Cycle in the thirteenth century. Though undoubtedly a contributing factor given the structure’s popularity at the time, this theory neglects to consider more common and proven factors of audience appeal, particularly the appeal that similarly transcends temporary trends and tastes. When considering Arthurian legend’s universality, it is important to acknowledge what elements remain consistent over the centuries as opposed to what has more freedom to change with the shifting tastes of the cultures it touches. Arthurian legend, despite the massive changes it has undergone, maintains elements that allow audiences across time to accurately identify it as Arthurian legend. Though stories can carry elements popularized or introduced by Arthuriana in the modern day, those elements do not necessarily make that story Arthurian in the perception of the reader. However, there are stories that change narrative structure, medium, time, place, and even popular plot points, that are still recognized as Arthurian. A similar phenomenon can be seen outside of Arthuriana in more contemporary stories that outlast their expected literary lifetimes. With this in mind, this presentation will consider the ways that Fan Studies explore the communities, individuals, and passions that have replicated this phenomenon. When engaging with this area of study and the elements that source it, a pattern emerges, showing a characteristic that commonly fuels the burgeoning universality of these celebrated stories. In fan works, things like narrative structure, medium, time, and plot all change freely, allowing for the consistencies to become clear. The characters, their bonds, their flaws, and their dramatic needs remain consistent across ever-changing landscapes, be it in fandom circles or the centuries and cultures touched by Arthurian legend. With this guide from other stories and their early universality, my paper will make it clear that an audience appeal substantial enough to transcend centuries is ultimately accessed through characterization, an essential element of the Arthurian legend.

Subconscious Comprehension of Structural Forms: An Eye-Tracking Study

March 21, 2024 12:00 AM
Authors: Jared K Bradshaw. Mentors: Brandon Ro. Insitution: Utah Valley University. This research seeks to analyze if there exists an understanding of structural design principles among untrained humans. Building forms and styles have evolved since the earliest structures. For thousands of years buildings were limited by naturally occurring materials. Designs of those periods reflected the structural principles of those materials. In the last few hundred years technological advances have provided structural methods which radically altered how buildings can be designed. An example is the difference in column spacing between historic and modern buildings, where the former has much tighter spacing due to natural material’s spanning limitations. To analyze the understanding of untrained humans an eye-tracking study was conducted using A.I.-3M-VAS eye-tracking software. This technology utilizes artificial intelligence to graphically display eye gaze sequences, patterns, and durations of focus. The software reflects the first few seconds of eye-tracking, providing insights into subconscious reactions before a logical response is formed. Images of structural elements were designed digitally to reflect a variety of forms, maintain cohesiveness, and remove visual variables. Each image was individually processed through the software providing isolated results. The results of the study show consistent patterns of focus on locations of structural significance, such as bearing points, connections, and material loads. The consistency by which these concepts received focus concludes that there is an innate human ability to locate structural methods of building. Of note the structural forms which adhered to the limits of natural materials registered different eye tracking patterns than the modern manipulated material forms. The historic methods displayed even tracking throughout the structure, whereas the modern methods created hot spots at the points of greatest structural significance. The differences further emphasizes that untrained people are not limited to just understanding familiar structural forms. This will allow for further research on the physiological effects between form types.

Crafting Secure System Messages

March 21, 2024 12:00 AM
Authors: Spencer Thompson. Mentors: Sayeed Sajal. Insitution: Utah Valley University. The widespread use of Large Language Models (LLMs) in various industries raises critical concerns about user data privacy and security. This research focuses on two key vulnerabilities: prompt attacks and unauthorized retrieval of sensitive training data. We employ a straightforward methodology to craft effective system messages that neutralize malicious queries in real-time, thereby mitigating prompt attacks. To prevent the unauthorized extraction of sensitive information, we build on the concept of strong system messages. We aim to identify a system message that minimizes computational overhead while maximizing effectiveness. Our results demonstrate that a strategically-crafted system message can guide an LLM's output in a manner that enhances data security without compromising computational efficiency.

An Analysis of the Neuroscience of Love and the Physiological Similarities it Holds to Addiction

March 21, 2024 12:00 AM
Authors: Audrey Wells. Mentors: Fredric Govedich. Insitution: Southern Utah University. This project is an interdisciplinary meta-analysis of literature across neuroscience, psychology, biochemistry, and biological anthropology. I am interested in comparing the neural physiology of love relationships to that of recreational drug use. I have cross referenced studies on the areas of activation and neurotransmitter level changes for each of these experiences. Both of these activities, specifically when comparing drugs to the infatuation stage of a relationship, show a dramatic increase in the reward complex within the center of the human brain, as well as an increase in risky behavior and obsession with the object of attraction/addiction. I then continued in an analysis of the termination from either positive stimuli, namely, rejection from a lover, and recreational drug withdrawal. I have found that within the motivational sectors of the brain, activation when viewing your rejector, as well as the heightened dopamine produced, show comparable similarities to those who are experiencing an active physiology drug withdrawal.

Group Theory for Procedural Content Generation: Towards Generating Objects from Mathematical Description

March 21, 2024 12:00 AM
Authors: Jonas P Knochelmann. Mentors: Rogelio E. Cardona-Rivera. Insitution: University of Utah. Despite the highly technical nature of Procedural Content Generation (PCG), the holistic study of the discipline is minimal and qualitative. We argue that this gap exists because there is no formal framework to talk about PCG artifacts and algorithms and propose the mathematical field of group theory to serve as such a framework. Group theory is a well-established discipline that has been embraced in chemistry, physics, and art, with tools for analyzing, combining, and generating objects based on their structure. We outline a specific method for applying group theory to PCG and explore a number of case studies in the hopes of developing a more unified formal framework for future study.

The effects of stinging nettle oil on the vascular smooth muscle in frogs

March 21, 2024 12:00 AM
Authors: Tia Dudley, Ty Erickson. Mentors: Matthew Weeg, Mary Jo Tufte. Insitution: Southern Utah University. The pharmacological investigation of plant essential oils has been expanding due to their suspected health implications. Research supports that plant essential oils have cardiovascular benefits, including reducing blood pressure and managing hypertension. Our research centers on stinging nettle and its effect on the vasculature in frogs. Existing evidence shows that stinging nettle can be used to treat hypertension, a disease intensified by vasoconstriction. Our study aims to investigate if stinging nettle causes a relaxation in smooth muscle and vasodilation. We administered stinging nettle on the vasculature in frogs and measured the diameter of the blood vessels before, during, and after the application. Results show that the application of stinging nettle has a vasodilating effect on some of the smaller blood vessels. The vasodilation is a potential mechanism for the anti-hypertensive effects of stinging nettle. These findings illustrate a probable avenue in cardiovascular medicine and highlight the potential of plant oils in reshaping the landscape of modern health.

Foreign Textiles at the Early Christian Fag el-Gamous Cemetery in Egypt

March 21, 2024 12:00 AM
Authors: Jenna Norris. Mentors: Kerry Muhlestein. Insitution: Brigham Young University. In the hot and dry climate of the Fag el-Gamous Cemetery in Egypt, a wide range of elaborately woven textiles have been preserved, each with unique characteristics and technical elements. Through analyzing technical elements, this research aims to reveal evidence of foreign textile production or materials incorporated in Fag el-Gamous burials. The BYU Egypt Excavation Team has been excavating at the cemetery for over 40 years, uncovering important information about the region’s ancient inhabitants. Due to their exceptional preservation, textiles can provide significant insights into the lives and identities of the individuals buried at the site. While studies have been conducted in the past to address how socioeconomic status and religious affiliation are reflected in textiles, more remains to be learned about how foreign connections and trade affected textile production in the Fayoum region. This research aims to utilize both technical and design analysis to identify foreign textiles—including analyzing weaving techniques, thread manipulations, and woven motifs. It will also aim to use these forms of analyses to detect potential indications of immigration, providing a foundation for future research into connections between immigrant status and funerary practices.

Conserving a keystone predator in the Americas: integrating phylogenomics, biogeography, and species-level taxonomy for a widespread army ant genus

March 21, 2024 12:00 AM
Authors: Megan DuVal, John Longino, Rodolfo da Silva Probst. Mentors: John Longino. Insitution: University of Utah. Army ants (Formicidae: Dorylinae) are top predators throughout most tropical and subtropical regions of the world. Their nomadic colonies and cooperative social hunting make them behaviorally and ecologically unique keystone species that are of conservation concern. Their status as nomadic top predators makes army ants vulnerable in areas affected by habitat fragmentation. An obstacle to conservation efforts is the outdated army ant species-level taxonomy, which hasn’t been updated since the 1950s for many genera. For Labidus, a widespread and ecologically important army ant genus in the Americas, there are currently seven valid species recognized solely based on morphology of workers and/or males. Three species are only based on males, which need to be associated with their respective workers, and within the four primarily worker-based species, there are likely cryptic species. To address these issues, we applied cutting-edge phylogenetics and phylogenomics to update the species-level taxonomy. To construct our phylogenetic tree, we used ultraconserved elements (UCEs, which use thousands of regions across the genome and can accurately infer evolutionary relationships across broad timescales) from 17 specimens, 66 COI barcodes from the Barcode of Life Database (BOLD), and 35 new COI barcodes obtained through in-house Nanopore sequencing. Through our analyses, we found that the genus Labidus contains at least 11 species and that all of the previously recognized wide-ranging species are made up of multiple cryptic species with more restricted ranges. We were able to associate all three previously identified male-based species with their respective workers. We have also found patterns of parallel and overlapping biogeography across multiple Labidus clades. Our UCE+Nanopore approach allows for an updated taxonomy of Labidus, leading to a better understanding of its evolutionary history and a better ability to promote its conservation.

Income Inequality for Women in the Psychology Field

March 21, 2024 12:00 AM
Authors: Jacob Willoughby. Mentors: Joshua Price. Insitution: Southern Utah University. Gender pay inequality remains a persistent and widely discussed issue across various professions and industries. I was curious about the extent that this issue affects the field of psychology as it is an industry that is quite significantly dominated by woman. This econometrics paper delves into the complex landscape of possible gender-based wage disparities within the realm of psychology. By employing rigorous statistical analysis and econometric techniques, I aim to uncover the underlying factors contributing to the pay gap between male and female psychologists. Understanding the intricacies of this phenomenon is not only essential for promoting fairness and equality in the workplace but also for fostering a more inclusive and diverse community within the field of psychology. This study endeavors to shed light on the extent of the pay gap, its determinants, and potential policy implications to address this critical issue in the profession.

A Place for the Arts: Creating Spaces for Cross-Community Contact in Belfast

March 21, 2024 12:00 AM
Authors: Addie Ressler. Mentors: Jacob R. Hickman. Insitution: Brigham Young University. Since the conflict named “the Troubles”, infrastructure and symbolic imagery have been used to divide areas within Northern Ireland and mark territory between Loyalist and Republican communities. While the larger community in Belfast is still held by these physically and socially enforced boundaries, the art community actively defies these restrictive borders by renting, renovating, and then transforming buildings and spaces within segregated areas. In this paper, I analyze the unique and incomparable role that artists can play in pushing against the sectarian attitudes that persist within Belfast. Their success is dependent, in part, on the spaces they occupy and the use of those spaces. I argue that because artists infuse their studios and buildings with metaphysical meaning, artist collectives are able to provide neutral spaces where individuals from the opposing communities can come in contact with one another. Ultimately, members of the art community in Belfast strive to produce a commune-like entity that can act as a microcosm for an ideal Belfast.

Fremont Red-on-Gray Pottery

March 21, 2024 12:00 AM
Authors: Talia Berglund. Mentors: Michael T. Searcy. Insitution: Brigham Young University. Fremont Red-on-Gray Pottery Specific to the Northern Macro-Region of inhabitance, there has yet to be a comprehensive cataloging of Fremont red-on-gray ceramics. As such, I will be asking the following research questions in regard to this type of ceramic: What designs were painted on Great Salt Lake red-on-gray? And how do these designs compare to other Fremont ceramic types? In order to effectively answer these questions, I will look at Great Salt Lake Fremont ceramic vessels and sherds with traces of red paint on the surface, with a particular emphasis on the artifacts found at Hinckley mounds but comparing them to Wolf Village specimens as well. The research will include recording the shapes and designs that are painted on the vessels, as well as measuring width and length of these lines and shapes. I will also investigate what the red pigment is made out of–using either PXRF or microscopic analysis. These methods will generate a catalog of designs found on red-on-gray ceramics, as well as a data set that will allow me to look for patterns among the painted designs. I plan to develop a general typology of red-on-gray Fremont pottery based on the sample investigated.In carrying out this research, we should be able to assess whether or not the Fremont in the Northern Macro-Region shared painting practices with other Fremont in different areas, and thus possibly determine how they viewed themselves as belonging to or different from other nearby groups of people. If a pattern emerges and red-on-gray designs are shared between groups, then perhaps they interacted with and associated with those groups. If there is a lack of shared practices and designs, the opposite could be potentially true.

Faunal Remains from Hinckley Mounds

March 21, 2024 12:00 AM
Authors: Amber Clayton. Mentors: Michael Searcy. Insitution: Brigham Young University. This summer, an excavation took place at the Hinckley Mounds, which included the recovery of many different artifacts. Artifacts found include faunal bones—the main object of my research project. The Fremont people left behind so many different things for us to find. They hunted particular animals; which can indicate which animals may have contributed most to their diets and may have also been used to contribute to other aspects of their lives. Many questions can be answered with the analysis of faunal bones: Which faunal bones show up more than others? What does the variety of animals teach us about the Fremont people at Hinckley Mounds? Through the analysis of the faunal assemblage I will be conducting, I will be able to tell which animals are more common in the assemblage. I believe this will also be able to tell me which animals played a more prominent part in the lives of the Fremont people.My primary goal is to determine the typology of the faunal bones by using the comparative collection at the Museum of Peoples and Cultures in order to see if I can identify the animals left behind by the Fremont people at Hinckley Mounds. Hundreds of faunal bones were found, so many of them that it will be impossible for me to analyze all of them during fall semester. However, I will strive to analyze representative sample of them so I have some good sample data. I will then use the data from 2023 and the results from the 2015 field season to write up the research for this project.

What role does gig work play in bridging or widening the gender pay gap among underrepresented groups?

March 21, 2024 12:00 AM
Authors: Katrina Kim. Mentors: Joshua Price. Insitution: Southern Utah University. The gender wage gap has been a persistent issue in the labor market for several decades, resulting in inequalities in workforce opportunities for women. Traditionally, this gap has often been attributed to observable characteristics, referred to as "human capital determinants" which characterized jobs in to male-dominated and female-dominated roles. This division was based on factors such as job requirements and physical labor, leading to disparities in wages. However, recent decades have seen a narrowing of the gender wage gap due to increased opportunities and the emergence of the gig economy. While Uber is one of the most widely recognized gig economy platforms, this study aims to explore whether the gender wage gap persists or narrows across various technology-based job markets. Utilizing data from the Gig Economy Data Hub, which includes information from gig worker surveys, tax returns, demographics, and more, this research seeks to identify the factors influencing gender pay disparities. The study will examine income differentials between male and female gig workers across multiple platforms, taking into account various wage determinants and tax statuses. Additionally, demographic variables including race and household income will be considered as wage disparities exist not only between genders but also among different minority groups. By examining various factors, this study will contribute to a more comprehensive understanding of the impact of the gig economy on gender pay equity and inform potential policy interventions aimed at addressing these disparities.

The Transmission of National Identity: A Case Study of Japan's Memorialization of the Past

March 21, 2024 12:00 AM
Authors: Ashlyn Clark. Mentors: Lynnette Finau. Insitution: Brigham Young University. Festivals, museums, bookstores, and Shinto shrines might not seem to have a lot in common, but implicit Nationalist ideals find their way into each of these, leaving their mark in the transmission of Japanese identity. In this study of Yasukuni Jinja and the Yushukan Museum (the Tokyo National War and Peace Memorial shrine and museum), it becomes more clear how these relate to one another, how they relate to Japanese identity, and how exactly they are nationalist in nature. Honor, sacrifice, tradition, and war come together to create a beautiful, unifying narrative that links ancestors with descendants, maintaining national identity and continuing to transmit their traditional ideals.

Seasonal Effects on Drosophila Development Rates

March 21, 2024 12:00 AM
Authors: Peyton Jackson. Mentors: John Chaston. Insitution: Brigham Young University. This study explores the relationship between seasonal variations and the development rates of Drosophila Melanogaster. Flies are closely monitored in a controlled laboratory setting after being transferred from outdoor cages across different seasons. In the outdoor cages, the introduction of the bacterial strain A. orientalis DmW_045, commonly referred to as '45,' enhances development rates and ensures consistent data collection. Axenic flies, created by thoroughly sterilizing fly eggs with bleach to eliminate external bacteria, are employed to isolate genetic influences on the relationship between season and development rates. The core methodology involves two groups: axenic flies treated with '45' and a control group unexposed to '45.' This approach guarantees data accuracy and assesses development rates based purely on genetics. Development rates are measured by marking eclosed (hatched) pupae on vials at specific intervals. The research seeks to unveil the correlation between seasonal variations and fly development rates, shedding light on the role of seasonal factors in shaping development. This study explores the interplay between seasonal variations and Drosophila fly development, emphasizing genetics and environmental factors. Its potential significance lies in providing insights beneficial for ecological and genetic studies, potentially offering a clear genetic link between seasons and development rates that can enhance our understanding of the natural world.

A Study of Polymer Bonding and the Restoration of Fragmented Ancient Pottery

March 21, 2024 12:00 AM
Authors: Ellie Martin. Mentors: Cynthia Finlayson. Insitution: Brigham Young University. Pottery reconstruction allows archaeologists to better understand their artifacts and gain a more complete understanding of ancient ceramic techniques. Reconstruction techniques have evolved over time that strive for both better conservation practices and long-lasting results, as well as the use of bonding materials that are reversible rather than permanent. This poster examines the process of utilizing an acetone-based glue consisting of dissolved polymer beads of differing strength solutions. The entire process with be illustrated by step-by-step photos and directions as well as the quality of the final results. Two layers of different solution consistencies are applied to the pottery in different stages before the pieces are joined together. The first layer of glue is a thin coat made of 5% polymer and 95% acetone, and it is applied to any edges that will be refit. This layer fortifies the sherd and ensures that the glue applied is not stronger than the sherd itself. After the first layer has dried, the second coat of glue, made of 12% polymer and 88% acetone, is added to each piece. The sherds are then joined and placed in a secure location to dry, such as a bin of silica beads. Acetone-based polymer glue is strong and flexible, yet also dissolvable. Any mistakes can be unmade with the careful application of small amounts of acetone, and no restoration action is utilized on the pottery fragments that cannot be undone. This method of reconstruction is safe, secure, long-lasting, and meets modern conservation standards.

Designing Inducible DNA Constructs for the Chicken

March 21, 2024 12:00 AM
Authors: Lant Jenkins, Dalyn Davis, Caleb Kratt. Mentors: Jeffery Barrow. Insitution: Brigham Young University. Currently, nematodes, fruit flies, and zebrafish are effective models for gene manipulation due to their rapid embryonic development and capacity for producing a large number of offspring. Avians such as the chicken have also served as embryonic models and have proven to be powerful tools for exploring developmental processes such as neural tube or limb development. Because of high chick fecundity, a relatively short period of development, and the accessibility of the chick embryo, the chicken would make an excellent model for gene manipulation that would significantly enhance our study of the relationship between genes and phenotypes in vertebrates. The aim of our research is to develop a line of genetically modified chicken germ cells into which new DNA vectors can be seamlessly introduced via cassette exchange. The design of the germ cells is such that the DNA vectors will be incorporated into the chicken genome at specified safe harbor locations, areas of euchromatin where the introduced DNA will not interfere with other genes. These modified germ cells can then be injected into chicken embryos and contribute to the chick’s germline. We anticipate that this model for modifying the chicken’s genome will significantly enhance our ability to introduce new DNA vectors, making the chicken a more desirable model for studying embryonic development via genetic manipulation.

Antihistamines Blunt the Effect of Localized Vibration on Arterial blood Flow

March 21, 2024 12:00 AM
Authors: Dustin Edmonds, Devin Needs, Riley Fisher. Mentors: Brent Feland. Insitution: Brigham Young University. Research questionHow does localized vibration increase blood flow? We know that localized vibrations increase blood flow. We wanted to know if this is done through the release of hormones, specifically histamines. Relevant research contextResearch on blood flow has been done using whole-body vibration but research on the effects of localized vibration on arterial blood flow is scant. To date, there are only a couple of research articles on massage guns despite their prolific use in the sports industry. No research to date has attempted to assess the mechanism behind the increased blood flow that results from localized vibration.MethodsTwenty-one participants completed this study, 11 males and 10 females, mean age of 22.1 +/- 2.0 years. The mean male height 181.3 +/- 9.6 cm and weight 80.7 +/- 19.0 kg. The mean female height is 169.2 +/- 7.5 cm, and the mean weight is 64.5 +/- 9.3 kg. All subjects were “recreationally active” and exercised at least three times a week for thirty minutes a day. Excessive activity or high-level athletes were not allowed to participate. Each subject received localized vibration to the gastrocnemius (vibration of 47 Hz for 10 minutes) with and without an antihistamine drug by reporting to the lab on 2 separate days. The non-antihistamine trial was performed first, followed at least 24 hours later by ingesting an antihistamine (180 mg of fexofenadine) 1 hour before the trial. Blood flow in the popliteal artery was measured using an ultrasound. Measurements (mean and peak blood velocity, volume flow, popliteal diameter, and heart rate) were taken before localized vibration treatment and then taken at intervals for 19 minutes after the treatment.AnalysisWe used a cell-means mixed model to statistically compare the effect of vibration on blood flow with and without antihistamines. This was done by evaluating the blood flow response immediately post vibration and comparing that to baseline values for both control and antihistamine conditions. Results and ConclusionThere was a significant increase in blood flow without antihistamine while administration of antihistamine blunted the blood flow response and resulted in an insignificant increase in blood flow. In the tests with the antihistamine, we saw an insignificant change in blood flow immediately post vibration, resulting from the localized vibration. From this experiment, we hypothesize that increased blood flow from localized vibration is due to activation of mast cells which release histamines and that this cellular activation is force dependent.

Fish Tattoos: The Evolutionary Cost of Black Spot Disease

March 21, 2024 12:00 AM
Authors: Eric Morris. Mentors: Jerry Johnson. Insitution: Brigham Young University. Black Spot Disease (BSD) is a parasitic infection that occurs when trematode parasites burrow into the skin of a fish and form a cyst. The infected fish releases black pigment around the cyst creating a visible black spot. Fishes can have different levels of infection ranging from a few cysts located on their skin to an entire body speckled with these markings. Parasitic diseases typically come with a cost to the host species. Little research has been conducted examining the cost of such diseases in the placental live-bearing fish Brachyrhaphis rhabdophora. My study examines the influence of BSD on female association preferences by providing female Brachyrhaphis rhabdophora dichotomous choices between males who appear to be healthy, slightly infected, moderately infected, and highly infected. The different levels of infection in the males are simulated by ink tattooing.

Gene analysis of gut microbiota that improves chill coma recovery rates in Drosophila Melanogaster

March 21, 2024 12:00 AM
Authors: Lauren Heath, John Chaston. Mentors: John Chaston. Insitution: Brigham Young University. Mounting evidence shows that gut microbiota disruption is related to several physiological processes and disease development in mammals; however, the mechanisms by which these processes take place are not fully understood due to the complexity of the mammalian gut microbiome. Studying the fruit fly, Drosophila Melanogaster proves to be a valuable model for understanding the gut microbiome on a smaller scale. Previous research has identified microbiota disruption alters the fly’s ability to cope with thermal stress and causes slower chill coma recovery times. Chill coma recovery is an important survival trait and stress response in Drosophila flies. Microbiota may affect the ability of hosts to tolerate stressful situations. The purpose of this project is to determine the effect of different bacterial strains on the mechanisms of chill coma recovery through a metagenome analysis of different bacterial strains. I hypothesize that certain microbe genes will increase chill coma recovery times. To test this assumption, I will mono-associate by flooding different groups of eggs with a microbe wash and infusing their food with the same bacteria strain. After cultivation, a chill coma will be induced by placing mature adult flies in empty vials on ice for three hours, and then the time for each individual to stand up after their transfer to room temperature will be recorded. Subsequently, I will assess cold tolerance, and evaluate the rates of recovery. With this, we can further identify the mechanisms of the chill coma recovery process by pinpointing specific proteins necessary for this process through a metagenome-wide association approach (MGWA) and gene analysis. If I observe no effect of the bacterial strains on chill coma recovery times, I can test different mixes of microbes to determine if improved recovery rates are a side effect of global metabolic changes caused by decreased biodiversity in the gut of drosophila flies. Studying the metabolic processes of Drosophila allows us to unravel further the mechanisms by which gut microbes affect the fitness and health of their host. My findings may be extrapolated to further understand the human gut microbiome.

ATP and Dopamine Co-Release in the NAc

March 21, 2024 12:00 AM
Authors: Jonathan Dickerson, Christian Ahrens, Zach Valentine, Sara Linderman, Hillary Wadsworth, Lauren Ford, Jordan Yorgason. Mentors: Jordan Yorgason. Insitution: Brigham Young University. The nucleus accumbens (NAc) is a major component of the reward pathway in the brain. The role of ATP as a neurotransmitter within the NAc has largely remained unstudied. Multiple experiments have hinted at larger roles ATP may have in other areas of the brain, but not yet in the NAc to our knowledge. Our goal was to characterize ATP release in the NAc, in an attempt to pave the way to finding novel methods for treating/preventing addiction. Fast-scan cyclic voltammetry (FSCV) was used to track ATP and dopamine release in the NAc of mouse brains, evoked with electrical stimulations before and after application of various drugs. Blocking nAChR’s and NaV channels reduced both ATP and dopamine release. Blocking DAT’s enhanced release, but blocked clearance of both ATP and dopamine, and activating the immune system with LPS increased release of both ATP and dopamine. Changes in dopamine and ATP release after drug application were definitely correlated, but not proportionally so. While in some instances, the same mechanisms previously thought to work just with one neurotransmitter or the other had effects on both, changes in ATP signaling cannot be fully explained by dopaminergic machinery in the NAc.

Keystone Species in an Urban Environment: Do Raptors Control the Mexican Gray Squirrel in Mexico City?

March 21, 2024 12:00 AM
Authors: Byron Adams, Elias Johnson, D Alejandro Espinosa-Lucas, R Darío Perez-García, Israel Solano-Zavaleta, J Jaime Zúñiga-Vega, Gonzalo A Ramirez-Cruz. Mentors: Byron Adams. Insitution: Brigham Young University. Urbanization has forced animals to respond to novel environments. One of the challenges of urban ecology is that it is unknown if the ecological processes that take place in wild conditions also occur in urban environments. In natural ecosystems, key predators can limit prey abundance and have a widespread effect on trophic levels. Here, we examine a predator-prey interaction in Mexico City, an urban ecosystem where prey can be evaluated in the presence or absence of apex predators. Nearly all original ecosystems in Mexico City have been converted into man-made structures. Many of the green spaces in the city contain populations of the Mexican gray squirrel. These green spaces are also inhabited by different species of raptors, the most frequent being Harris’s hawk, Cooper’s hawk, and sharp-shinned hawk. Little is known about interactions between raptors and squirrels in terms of demographic parameters. We do know, however, that raptors prey on squirrels. We predicted that in parks where raptors were present, there would be fewer squirrels than in parks where there were no raptors. We studied the relationship between raptors and squirrels using occupancy models to determine the environmental factors that affect the presence of both squirrels and raptors. We then tested if the presence of raptors influenced the occupancy probability of squirrels. Lastly, we estimated the abundance of squirrels in parks, both where raptors are present and where they are absent. Contrary to our predictions, we found no evidence that predators predict squirrel abundance. However, we did find evidence that the presence of raptors can be predicted by the abundance of squirrels. These results suggest that this predator-prey interaction in Mexico City parks could be relatively recent and still not in equilibrium, or that other factors may be affecting the dynamics between these two urban populations.

Red Alert! Deciphering Seasonal Color Patterns in Utah Dragonflies and Damselflies

March 21, 2024 12:00 AM
Authors: Eva Driggs, Megan Cahoon, Seth Bybee. Mentors: Seth Bybee. Insitution: Brigham Young University. Odonates (dragonflies and damselflies) exhibit diverse coloration. These vibrant colors are important for species recognition, camouflage, and mate recognition. Adult odonates emerge in late spring, mate and reproduce, and die by fall. As color and seasonality are both important aspects of the adult stage in odonates, we pose the question: Does the odonate community color composition change over the season?We hypothesize that different colors within the odonate community will peak in abundance at different times in the season. We conducted population estimates weekly at a local park in Provo and analyzed data from Utah, the Great Basin, and the West Coast (GBIF). From this data, we found that generally, blue odonates have the highest abundance throughout the season, but red odonate populations persist later in the season while blue populations decline which may be due to seasonal changes in heat and light.

Do Predators Cause Maternal Effects in Livebearing Tropical Fish?

March 21, 2024 12:00 AM
Authors: Nolan Rodeback, Jerald Johnson. Mentors: Jerald Johnson. Insitution: Brigham Young University. The environment plays a crucial role in the development and evolution of organisms. In some cases, the environmental pressures on a mother may result in changes of offspring phenotypes. This phenomenon, called maternal effects, might occur in the tropic fish species Brachyrhaphis rhabdophora. I will conduct an experiment to test if maternal effects can be induced by the presence of a predator. To measure this we will look at maturity age and growth rates in the offspring where mothers are reared in the presence or absence of predators. If predators have an effect, offspring should mature at earlier ages and have faster growth rates than individuals with mothers reared in the absence of predators.

CICNT surfaces block Staphylococcus aureus biofilm formation on implanted devices in mice

March 21, 2024 12:00 AM
Authors: Brooklyn Jones. Mentors: Bradford Berges. Insitution: Brigham Young University. Staphylococcus aureus (SA) forms biofilms that cause considerable morbidity and mortality in patients who receive implanted devices such as prosthetics or fixator pins. An ideal surface for such medical devices would inhibit biofilm growth. Recently, it was reported that surface modification of stainless-steel materials with carbon-infiltrated carbon nanotubes (CICNT) inhibits the growth of SA biofilms. Through previous research, we investigated this antimicrobial effect on titanium (Ti) materials with CICNT coated surfaces in a variety of surface morphologies and across a broader spectrum of SA isolates. We have in vitro evidence that carbon nanotube-treated materials are effective at preventing SA biofilm formation on Ti, the most common material used in human implanted devices. We now wish to study the effects of carbon nanotube treatments on prevention of SA biofilm formation in vivo which has potential value to improving human health .

Epigenetic Marks of Antiaging Pioglitazone Hydrochloride (PGZ) on Progeny

March 21, 2024 12:00 AM
Authors: Wesley Hendricks. Mentors: Steve Johnson. Insitution: Brigham Young University. Pioglitazone Hydrochloride (PGZ) is a well-accepted treatment of type-II diabetes and has been shown in previous studies to increase lifespan of C. elegans. The agonist has been shown to affect the insulin, IGF-1 signaling pathway (IIS), dietary restriction (DR) and germline signaling pathways. Previous studies have not been able to identify epigenetic marks that are a result of the pathway effects of PGZ (Jia Wenguan et. al). This study seeks to understand how subsequent generations are affected by antiaging compounds and what epigenetic marks are transmitted through the germline of C. elegans from these three pathways. After exposure, through lifespan tracking, we hope to see a change in transgenerational longevity. Using RNAi, we then plan to knockout known genes in each pathway. We hope to see that intestine-germline pathway and maintenance genes that are known to function in each pathway are required for the longevity effect.

Natural Transformation in Staphylococcus aureus biofilms

March 21, 2024 12:00 AM
Authors: Julia Gilpin, Lucy Bowden, Sela Harris, Elisa McRae, Jenny Bean, Brooklyn Jones. Mentors: Bradford Berges. Insitution: Brigham Young University. Staphylococcus aureus (SA) is a significant human pathogen that has acquired antibiotic resistance, posing a global health threat. This bacterium is prevalent in livestock, raw meat, and healthcare settings, leading to infections ranging from mild to life-threatening. The emergence of multi-drug resistant strains, such as Methicillin-Resistant Staphylococcus aureus (MRSA), further complicates treatment. The mechanisms of antibiotic resistance transfer, especially within biofilms, remain poorly understood.This research aims to investigate horizontal gene transfer within biofilms of SA isolated from humans. Leveraging the work of the Berges laboratory and techniques used by other researchers. The experimental design involves the use of heat-killed cells as donors to prevent conjugation, shedding light on how biofilm structure influences transformation efficiency.To address the hypothesis that biofilms serve as hotspots for horizontal gene transfer, the research employs a two-component system for upregulating natural competence genes in SA under biofilm growth conditions. This approach will allow us to detect natural transformation, advancing our understanding of SA infections closely associated with biofilm formation. If successful, this study will provide insights into how SA acquires antibiotic-resistant genes and may lead to the development of preventive measures and treatment strategies to combat drug-resistant strains.

The Effects of Latitude and Other Microbiota on the Microbiota of Drosophila Melanogaster

March 21, 2024 12:00 AM
Authors: Connor Hough. Mentors: Johnny Chaston. Insitution: Brigham Young University. Many variables can have an effect on the microbiota (microbial community associated with an organism) which can, in turn, affect the health and lifestyle of the microbiota's host organism. One such variable is geographic latitude (distance away from the earth's equator) which was the subject of a portion of a study performed by Walters et al. in 2020 and a similar study performed by Henry et al. in 2022. Walters et al. determined that latitude had a significant effect on the composition of the gut microbiota in Drosophila melanogaster (fruit flies) while Henry et al. determined that latitude did not have a significant effect. To better understand what variables may have caused a difference in the results of these two studies I plan to perform data analysis on the data provided from both Walters et al. and Henry et al. Particularly, Henry et al. provided data about the microbiota of other sample types associated with D. melanogaster across the latitudinal cline such as the fruit fly excrement, the leaves in their environment, and their diet which consisted of apples and grapes. While this data was mentioned in Henry et al.’s paper I feel that a more in depth analysis of these sample types could bring insight about how these microbiota affect one another and how latitude affects each of them separately. I will use QIIME (a bioinformatics data analysis software) data analysis methods, such as alpha and beta diversity metrics, and R to analyze the data provided and create graphs. Because each sample type in the data was recorded with unequal sample sizes I will also need to make a new taxonomic graph of the sample types when measured proportionally to each other. To do this I will use QIIME to group the original feature table metadata from Henry et al. by sample type and return a new table with an equal number of samples for each sample type. With this done I will then be able to make a new bar plot using QIIME. I will then use this new set of adjusted data to analyze the relationships between latitude and each sample type as well as the relationship between each sample type to one another. I will also perform these data analytics methods on the data provided on fruit fly gut microbiota by Walters et al. and compare the results with the fruit fly gut microbiota provided by Henry et al.. I hypothesize that further analyzing the data from these sample types will reveal new correlations between the microbiota of these sample types and with latitude. If no new information is learned through this analysis then it will solidify Henry et al.’s claim that latitude does not significantly affect the microbiota. Alternative outcomes may show that there is not a correlation between the microbiota of sample types which would indicate that the microbiota exhibits a neutral behavior and is not selective. However, if my hypothesis is correct then these correlations would show that the microbiota of separate sample types are related to the microbiota of other sample types and that latitude does have a significant effect on the microbiota of each sample type. The results of this analysis will open up more pathways for study about the reason behind these correlations or the lack thereof.

Leveraging Machine Learning in Face Mask Formulation

March 21, 2024 12:00 AM
Authors: Alexander Goslin, Hazel Ticas, Morgan Covarrubias. Mentors: Daniel Scott. Insitution: Utah Valley University. In the evolving realm of personal care product development, striking a balance between ingredient choice, manufacturing intricacies, and consumer demands is pivotal. As the industry grapples with escalating costs and the clamor for novelty, there's an imperative to find methods that refine the development pathway, keeping both product quality and cost-effectiveness in check. Machine Learning (ML) emerges as a promising contender, proposing a data-centric route to formulation - from discerning patterns to forecasting efficacies, and even creating formulas themselves. This study delves into the intricacies of leveraging ML for personal care formulations, specifically emphasizing its role in substituting ingredients to either amplify a product's qualitative facet or reduce production costs. Despite the allure of ML, its integration into personal care isn't without challenges, given the industry's unique regulatory, consumer-centric, and trend-driven landscape. Through rigorous testing, evidence-based enhancements, and in-depth analysis, we aim to shed light on ML's functional dynamics in cosmetic formulations, underscoring both its potential dividends in cost and quality.

Detection of Beet curly top virus in Utah plants

March 21, 2024 12:00 AM
Authors: Elise Bennett, Megan Frisby, Rob Hess, Max Taylor, Erin Riggs, Alma Laney. Mentors: Alma Laney. Insitution: Utah Valley University. Beet curly top virus (BCTV) is a highly destructive virus found in most of the Western United States characterized by curling of the leaves, yellowing, and lack of produce. Historically, BCTV was a key factor in the decline of sugar beet production in Utah, formerly a large factor in the state economy. Commonly found in beets, tomatoes, and peppers, BCT is vectored by the beet leafhopper, Circulifer tenellus, as it feeds on the phloem tissue. Novel hosts of this virus found in Utah include sunflower, mallow, eggplant, hemp, big sagebrush, and Solanum jamesii, the Four Corners potato. Sunflowers showed symptoms of curled leaves and stunting. Similarly, the eggplant developed shriveled leaves and a mosaic at the leaf tips. Four Corners potato, a staple food source of the Indigenous peoples of the Southwest, displayed strong symptoms including stunting, leaf yellowing, and leaf curling. Weedy species and other garden plants displaying various viral symptoms were also collected for testing. Detection was done using published BCTV detection primers and rolling circle amplification with the use of Phi29 polymerase to prepare the genome for whole genome sequencing. A 518 bp region was sequenced to 4x coverage from eight host samples. To ensure the validity of diagnosis, a triple antibody sandwich ELISA was performed confirming the results. Considering the history of BCTV in relation to the agriculture industry of Utah, the discovery of novel hosts is cause for concern since this virus is adaptable and limits crop yield. The diagnosis of BCTV in native plants, such as the Four Corners potato and the big sagebrush, is pressing as it these local flora are unique to the region. The verification of BCTV in these novel hosts allows for the agriculture industry of Utah to prepare prevention methods including the monitoring of beet leafhoppers and increased integrated pest management strategies are needed to protect our local environment.

Monarch Butterflies - What's in their Color?

March 21, 2024 12:00 AM
Authors: Kyri Forman, Craig Thulin, Heath Ogden. Mentors: Heath Odgen. Insitution: Utah Valley University. The monarch butterfly (Danaus plexippus) uses orange filtering pigments in the eyes to discriminate between different hues of orange and yellow and these pigments are believed to be used for deciphering wing color during mate selection (Blackiston et al., 2011). However, it is not known if these orange pigments in the eyes match those in the wings, or if they are present in the wings or eyes of the white monarch (Danaus plexippus nivosus); a variant caused by a mutation in the wing pigmentation process. For this study, pigment extracts from the wings and eyes of typical orange monarchs and white monarchs were characterized using LCMS and fragmentation MS (including MSMS and MSn) and compared. Of the seven pigments known to occur within the wings of orange monarchs (Forman and Thulin, 2022), three were found in the eyes of orange monarchs and little to none of these pigments were present in the nivosus wings or eyes. This lack of orange pigment within the eyes of white monarchs may signify possible color blindness within this mutant. This is supported by previous reports of these butterflies being less likely to breed and forage for nectar, but behavioral studies will be needed to confirm this hypothesis further.

Green Hydrogen Production from Wastes by High Temperature Plasma Pyrolysis

March 21, 2024 12:00 AM
Authors: Veronica Gunyan, Minh Nguyen. Mentors: Kevin Shurtleff. Insitution: Utah Valley University. Our team’s project green hydrogen production from plastic waste by high temperature plasma pyrolysis aims to help aid in reducing waste by taking UVU’s recycled plastic waste, decomposing it using plasma pyrolysis, and turning it into clean hydrogen and carbon in a cost-effective manner. Pyrolysis is the thermal decomposition of organic materials in an oxygen-free zone. Green hydrogen comes from renewable energy and releases no CO2 by products into the air. The purity of the hydrogen can be improved by adjusting components such as temperature in the reactor, range, the gas used, the time frame, catalysts and other operational elements. Energy prospects can be determined by considering the energy consumed subtracted by that produced to determine the net output.

Analysis of Graphene Samples Using a 785nm Raman Spectrometer and Construction of a Carbon Spectral Library

March 21, 2024 12:00 AM
Authors: Seth Stringham, Audrey Elison, Kevin Shurtleff, Dustin Shipp. Mentors: Dustin Shipp. Insitution: Utah Valley University. Graphene, a single atom thick layer of carbon, has become a focal point of research in various fields due to its unique and diverse properties. As many researchers apply new methods to develop this material, it is crucial to have tools and practices in place to determine if the newly created sample is indeed graphene. This study focuses on using a 785nm Raman Spectrometer for analyzing graphene samples. The key analysis methods used in this study are Raman spectral analysis and the construction of a Carbon Spectral Library. The Raman spectroscopy, leveraging the G and 2D bands, helps identify the structural and vibrational properties of graphene. The Carbon Spectral Library provides a comprehensive collection of Raman spectra from diverse carbon-based materials, aiding in accurate comparison and identification. The study's findings emphasize the significance of the 785nm Raman Spectrometer as an effective tool for characterizing graphene samples.

The ABC conjecture and Mason's Theorem

March 21, 2024 12:00 AM
Authors: Juan Palencia, Tanner Probst, Clair Yeaman. Mentors: Machiel Van Frankenhuijsen. Insitution: Utah Valley University. Abstract: The ABC conjecture is an unsolved problem in mathematics first formulated by Joseph Oesterlé and David Masser. The conjecture attempts to show an analogy between polynomials and integers. This insight arises from the Stothers-Mason Theorem (also known as Mason’s Theorem). The theorem states that the maximum degree of a polynomial is always equal to or less than the number of distinct roots minus one. The ABC conjecture attempts to bridge this analogy by defining the height as the maximum algebraic number in the sum a + b = c where a, b and c are relatively prime. Masser and Oesterle define the radical as the sum of log p where p divides abc. Mason’s theorem states that the height is less than the radical minus one. It turns out that this is not true for the integers. Thus Masser and Oesterle formulated a conjecture which may be true. Over the past decades, this inequality has been strengthened and reformulated. Shinichi Mochizuki has recently published what he claims to be a proof of the conjecture, but many mathematicians are currently still working to understand it. The aim of our research is to better understand the height and radical in the ABC conjecture. In addition, we intend to explore the possibilities of expanding the Stothers-Mason Theorem. Since the ABC conjecture is concerned with an analogy between commutative rings (integers and polynomials), we are interested in seeing whether Mason’s Theorem for polynomials also holds for non-commutative rings, such as matrix rings and the ring of quaternions. In addition, we intend to explore the connection between the factorization of polynomials and finite Abelian groups.

Improved low-cost, solar water purifier to reduce clean water scarcity

March 21, 2024 12:00 AM
Authors: Fatoumata N'diaye, Kevin Shurtleff. Mentors: Kevin Shurtleff. Insitution: Utah Valley University. The use of solar energy for water purification purposes has proven to be an efficient tool with promising results which could help tackle the issue of water scarcity in developing regions of the world. The low-cost, solar water purification system built previously will be improved through increasing thermal conduction, enhancement of the water flow uniformity, strengthening of the piping system, increasing airflow inside the water purification system, and thus maximizing the clean water production rate. We used aluminum foil as the condensation surface with silicone caulk as a binding agent between the materials. We used ultra-violet resistant greenhouse plastic film to protect the purifier overall from sunlight damage. We measured the incident solar irradiance, airflow inside the purifier, temperature of the evaporation side, temperature of the condensation side, ambient temperature outside, conductivity of the dirty and clean water, and clean water quality/taste. Finally, we compared this data to previously collected data.

Thermoacoustic Heat Engine

March 21, 2024 12:00 AM
Authors: Euiyoung Kim, Bonnie Anderson. Mentors: Bonnie Anderson. Insitution: Utah Valley University. A thermoacoustic engine is designed to transfer heat energy into sound energy. Heat engines have a hot side (hot heat exchanger) and a cold side (cold heat exchanger) and use part of the heat flowing between them to do work. The engine in this study is shaped like a bottle with copper wire mesh heat exchangers in the neck. A heating element wrapped around the top of the neck supplies heat to the hot side and the base of the bottle is made of aluminum to keep the cold side at room temperature. When the temperature on the hot side reaches a threshold the sound wave is created. The heat goes from the mesh of the hot side into the “stack” (steel wool, in this case) and down to the cold mesh. The motion of air as it picks up and drops off heat along the stack excites the engine into one of its resonant frequencies. Different mesh configurations of the heat exchangers were tested to determine the impact on the acoustic properties of the engine. Principal Component Analysis was used to determine which parameters of the mesh affected the acoustic pressure the most. The outcomes of this research not only contribute to the emerging field of thermoacoustics but also provide valuable knowledge for the development of thermal sensors and electric energy in remote locations.

DMS-MapSeq analysis of 3' UTR in Human Genome

March 21, 2024 12:00 AM
Authors: Silvi Rouskin, Matthew Allan, Dragui Salazar. Mentors: Merrill Halling. Insitution: Utah Valley University. A 3’ untranslated region (UTR) is a non-coding region between the stop codon and the 3’ end of an mRNA. 3’ UTR can regulate post-transcriptional gene expression by influencing mRNA stability, translation, and localization. They fold into complex structures that contain elements and binding sites that interact with various molecules, including proteins and microRNAs (miRNAs). Despite the recognized importance of 3’ UTRs and their structural features, the vast majority of their structures in humans remain unknown. Indeed, the structures of long RNAs in general have been difficult to solve due to their heterogeneity and to the paucity of known, ground-truth RNA structures for training and validating models. This project aims to circumvent these limitations by characterizing the structures of 3,000 to 4,000 human 3’ UTRs. The project can be simply described as follows. The cDNA is received and prepared for PCR with the needed primers. After the PCR, genetic material is transcribed into RNA where dimethyl sulfate mutational profiling with sequencing (DMS-MapSeq) will be introduced. After this, it is reverse transcribed and prepared for sequencing. The project implements thousands of primers to facilitate the comprehensive identification of genes. The vast dataset of structure profiles will be used to develop an advanced machine learning algorithm to predict first the DMS-MapSeq results and eventually the structure of an RNA solely from its sequence. The preliminary results show that it is possible to determine hundreds, even thousands of 3’ UTR structures using DMS-MapSeq and the creating an accurate image of such structure. These results also contain druggable pockets that can be used in RNA based therapeutics in a near future.

Evaluation of Microplastic Pollution in Subterranean Systems and the Impact of Human Visitation

March 21, 2024 12:00 AM
Authors: Stone Smith, Ben Belt. Mentors: Sally Rocks. Insitution: Utah Valley University. Microplastics are particles less than 5 mm in length. These particles act as a vector for heavy metal and carcinogens, which have negative effects on human health. Often invisible to the naked eye, microplastics are extremely mobile and have been found in the most extreme parts of the planet, from the peak of Mount Everest to depths of the Mariana trench. Because microplastics are readily transported via air and water, microplastics have been found in every location exposed to wind or rain. However, one place that is sheltered from wind and rain are caves. In some subterranean environments, the earth acts as a natural filter of the water that descends into caves. It is suspected that caves will have lower levels of microplastics present in their environments compared to surface environments. However, another mechanism for microplastic introduction is human activity. Humans utilize plastics in relatively all synthetic items. Everything from clothing to packaging to regular household items employs the use of plastics, which can abrade to release microplastics. The goal of this research is to determine if caves with high levels of human visitation have higher concentrations of microplastics than caves with little to no human visitation. Analysis of subterranean water samples will reveal if microplastics are invading cave environments regardless of human activity, and through what mechanisms. A consequence of microplastic pollution in cave environments is the capture of plastic particles within mineral matrices. As mineral rich water evaporates in caves, the minerals left behind form speleothems that could capture plastic particles and thus preserve them (e.g. stalactites, stalagmites, soda straws, etc.). With a better understanding of the presence or absence of microplastics in caves, efforts can be made to minimize plastic accumulation and prevent microplastics from entering the geologic record of the cave.

The Primary and Secondary Metabolites of Tomato as a Response to Herbivory and Simulated Herbivory

March 21, 2024 12:00 AM
Authors: Iris Cepeda, Tabitha Weir, Jonathan Cook, Honey Ordonez. Mentors: Olga Kopp. Insitution: Utah Valley University. Solanum lycopersicum (tomatoes), are beloved herbaceous crops well known for their red bearing fruits. They are best grown in well-draining soils with access to full sun and are endemic to South America but grow all across the world where the conditions allow. Tomato fruits provide a quality source of phytochemicals and antioxidants such as lycopene, vitamin C, beta-carotene, and phenolic compounds which can substantially improve one’s healthy diet. S. lycopersicum are members of the nightshade family, which are known for their production of often toxic glycoalkaloids. The presence of these compounds usually deters herbivores by increasing their concentration as a defense response. There are, however, herbivores like Manduca sexta (tobacco hornworms) that feed on members of the nightshade family by dealkylating these glycoalkaloids. It is hypothesized that plants have the ability to modulate their defensive response based on queues from the environment and from their herbivore pests. Our research objective is to determine whether a S. lycopersicum plant undergoing defoliation from M. sexta will have the same molecular response as a plant undergoing simulated herbivory. Four treatment groups will be used with each treatment group having 8 replicates. Before treatment begins, the groups will be isolated by a non-permeable surface so air-borne defense signals from one group do not elicit a response in another. In the herbivory treatment group, M. sexta will be allowed to feed for a 24-hour period to account for diurnal and nocturnal herbivory, as well as high plant enzymatic response. Damage treatment 1 will simulate herbivory using a hole-punch, avoiding the midvein. Damage treatment 2 will simulate herbivory using a single transverse cut across the leaf blade and midvein. The undamaged control will have no herbaceous or mechanical damage done. After the treatment period, half of the leaf matter from all groups will be collected and frozen in liquid nitrogen to preserve all metabolic processes and GCMS will be used to analysis metabolite differences. The other half of the leaf matter will be analyzed using UV-spectrophotometer analysis with bromocresol green to compare the glycoalkaloid expression between the treatments. It’s expected that there will be a reduced expression of the defense glycoalkaloids in the herbivory group of S. lycopersium when compared to the two defoliation groups. While the three treatments could respond similarly to their treatments by primary metabolite expression, the type of defoliation could have a greater effect on this than the herbivory group.

Survey of Blow Fly (Diptera: Calliphoridae) Species Across Utah and Salt Lake Counties

March 21, 2024 12:00 AM
Authors: Haylee Beck, Lauren Weidner, Carl E Hjelmen. Mentors: Carl E Hjelmen. Insitution: Utah Valley University. Blow flies, scientifically known as family Calliphoridae, are important primary colonizers of remains that play a crucial role in decomposition, making them useful in forensic investigations for estimating a time of colonization (TOC). Unfortunately, there is little information on the species and distributions of blow flies present in Utah. Our research seeks to address this issue through collection, preservation, and identification of these blow flies. To collect the specimens, traps baited with chicken liver were set up in various locations across Salt Lake and Utah Counties. While we have only collected from these two counties thus far, our intention is to gather flies across the state, spanning both rural and urban environments. We will then use standard metrics of diversity to compare the species makeup in each location. The results of our research offer significant insights into the biodiversity, distribution, and ecological functions of these flies and their development in different ecosystems. In addition, this research has far-reaching implications in the field of forensics. These findings will contribute significantly to our understanding of blow fly distribution and behavior, providing valuable information for forensic investigations in our region.