Fine Arts

Authors: Benjamin VanDreew. Mentors: Kal Munis. Insitution: Utah Valley University. America as we know it today is politically very polarizing, divided, and full of misinformation. In this climate, buzzwords have become as prominent as ever either being spouted by politicians or news outlets or even trickling out to the public. In 2023 the word “woke” became a popular buzzword and is used in all sorts of contexts. So much so that in a lot of ways “woke” has lost any of its original meaning that was trying to be conveyed. In this study, I am out to discover what “woke” really means to Americans from all different walks of life. We have set up a conjoint list experiment that will be sent out in the form of a survey featuring randomized options. We will be able to get a better look at what aspects of American life people feel are the most “woke” and help define what the buzzword really means. This research will give us a deeper look into modern American culture and help provide clarity to this polarizing subject.

Authors: Megan Ritter Martin, Alley Fausett, Kristin Davenport, Malisa Brooks, Kent Hinkson. Mentors: Malisa Brooks, Kent Hinkson. Insitution: Utah Valley University. AbstractBackground: Present-day college students confront record-high levels of anxiety. In 2022, 36.9% of college students reported that anxiety affected their academic performance compared to 21.9% in 2015. This surge in anxiety presents a pressing concern. Prolonged anxiety poses a significant risk, potentially triggering various mental health challenges, including substance abuse, depression, and suicidal ideation and behaviors. Moreover, the adverse impact of anxiety on concentration and learning can result in academic difficulties that can persist throughout one’s life. Despite ongoing research, the correlation between anxiety and its influence on students’ academic performance remains inconclusive, primarily due to conflicting findings in prior studies within this domain.Methods: This study was designed to investigate the connection between academic achievement and anxiety, specifically in college students. A total of 1,359 University students from various US universities participated in this study from 2021 to 2022. Anxiety was measured by the General Anxiety Disorder 7 (GAD-7) scale, and academic performance was measured by Grade Point Average (GPA) and other markers of academic performance. To investigate potential mediating pathways, zero-order correlations were used to analyze the relationship between variables of interest. Further, t-tests were used to examine differences in key variables among demographic groups (e.g., veteran status, gender, race, ethnicity, etc.).Results: There was no statistically significant relationship found between students' academic achievement and their degree of anxiety. However, several academic performance variables besides GPA had inverse associations with anxiety. Further, several deleterious academic activities (for instance, “turning in a paper or assignment late”) were shown to be moderately associated with anxiety. Considered together, these findings suggest that anxiety has a complicated relationship with the GPA of the student, but multiple pathways connect it to academic performance.Conclusion: The present study contributes to the current literature surrounding the relationship between anxiety and academic performance. While traditionally, research into academic performance often focuses solely on GPA, additional academic performance variables were explored, providing insight into other relationships of potential significance. This creates an opportunity wherein the field may be able to better understand and support students by recognizing the impacts that anxiety has on their academic performance. These results highlight how crucial it is to treat mental health issues to improve university students' academic performance.

Authors: Emily Cherrington, Sam S Ingram, Chloe E Loveland, Ryanne Welch. Mentors: Olga Kopp. Insitution: Utah Valley University. Ocimum basilicum, commonly known as Genovese basil, is a frequently grown herb in the Lamiaceae family. It is used in food cuisines around the globe and is easily grown as a fresh-market herb for restaurants, farmer’s markets, and grocery stores. Basil has many antioxidants and anti-bacterial properties, but it is most commonly used as a culinary ingredient to add flavor to various dishes. Basil is very sensitive to cold, requiring well-draining soil with temperatures of 18°C to 27°C for germination. Consistent soil moisture is also necessary for optimum growth, and it prefers to stay moist to keep from drying out. In the face of global climate change, it becomes imperative to determine the adaptability of crucial agricultural crops -like basil- to varying nutrient levels in different substrate types across diverse environmental conditions. A plant's capacity to thrive in distinct substrates is intrinsically linked to the unique requirements of its seeds. The choice of substrate serves as the foundational element for cultivating healthy plants. This study centers on examining three pivotal aspects related to substrates: moisture retention, nutrient accessibility, and fungal growth. This led us to question whether the germination success of Ocimum basilicum differs depending on the substrate type. To test this question, we will plant Genovese basil seeds in four distinct substrate types: standard germination mix, 80/20 peat-perlite blend, compost-enriched soil, and an agar medium. Following their placement in the respective substrates, all seeds will be grown in a controlled growth chamber, subject to identical lighting conditions and a consistent temperature of 22°C to ensure uniformity across all treatments. At intervals of 1-2 days, diligent observations will be made to detect signs of germination. Once germination becomes apparent, we will meticulously document the results. Subsequently, this collected data will undergo analysis using the R Language. We anticipate that substrates rich in nutrients (specifically agar and standard germination mix) will exhibit heightened germination success. Investigating how substrate type affects the germination success of Genovese basil offers valuable insights with broad applications in horticulture and agriculture. It can enhance agricultural practices by pinpointing optimal soil choices for specific crops, increasing substrate efficiency to minimize resource wastage, and promoting sustainable and economical cultivation methods. Furthermore, this research contributes to a deeper comprehension of the environmental ramifications of crops and the diversity of crops in both controlled laboratory settings and natural environments.

Authors: Emmaline M Saunders, Michael A Stearns, Ami Ward. Mentors: Michael Stearns. Insitution: Utah Valley University. The Tuolumne Intrusive Suite (TIS), Sierra Nevada, California, accumulated magmatic rock from 95 to 85 Ma. Ar-Ar biotite dates require that temperatures within the TIS remained above ~300°C until ~79 million years ago. The protracted thermal history resulted in five texturally and chemically distinct units that young towards the center and was recorded by chemical and isotopic re-equilibration of the minerals. Challener and Glazner (2017) demonstrated that amphibole phenocrysts from the Half Dome Granodiorite (Khd) experienced greenschist-facies metamorphism. Amphibole phenocrysts host abundant inclusions of biotite, chlorite, feldspar, titanite, epidote, and apatite, which are interpreted to have crystallized via breakdown of magnesiohornblende. Additionally, Al zoning suggests fracturing and subsequent healing of the amphibole crystals occurred at near- or subsolidus temperatures. New EPMA and LASS-ICP-MS analyses of texturally related amphibole, titanite, feldspar, and biotite from the equigranular Khd place limits on the timing of amphibole breakdown and contextualize the low-temperature re-equilibration of many of the major minerals in the rock. Most of the amphiboles analyzed contain 0.5–6 wt. % Al2O3 corresponding to actinolite compositions, while feldspar pairs record ~475 ºC apparent temperatures. Titanite grains (re)crystallized between 91–80 Ma and contain 25–825 ppm Zr, which correspond to apparent temperatures between 550–710 ºC (150 ± 50 MPa, aTiO2 = 0.5 ± 0.1). The distribution of Zr in titanites is bimodal with the majority having <200 ppm Zr. Titanites younger than 87 Ma have decreasing Zr content and titanites included within actinolite amphibole contain the lowest Zr content (25–50 ppm) and youngest dates (85–80 Ma). Melt-present crystallization of titanite began at ~91–90 Ma, followed by both near and subsolidus (re)crystallization from ~88–86, concluding with titanite growth via hornblende breakdown from 82–80 Ma. These data taken together with previous investigations provide a continuous record of the rock’s chemical evolution driven by incremental emplacement and subsequent episodic autometamorphism of the equigranular Khd, and critically, any inferences regarding magmatic processes in the TIS must first account for the metamorphic re-equilibration of the rock.

Authors: Arahi Perdomo, Brooklyn Moore, Erin Kerr, Hula Santiago, Kylie Kay, Sarahi Joyner. Mentors: Krista Ruggles. Insitution: Utah Valley University. This research initiative centers on the experiences and learning outcomes of preservice teachers (PSTs) from Utah Valley University who volunteer to teach in the San Juan School District (SJSD) and the Navajo Nation. Our primary aim is to understand how this cross-cultural teaching experience shapes their future teaching practices, perspectives on diversity, and inclusion in education.Preservice teachers play a critical role in the future of education This study examines how their participation in a unique cultural context can enhance their preparedness as educators. By engaging in volunteer teaching assignments within the Navajo Nation, these students gain exposure to diverse cultural backgrounds; fostering cultural awareness and sensitivity.We seek to show the transformative impact of this experience on their personal and professional growth. Through interviews and observations, we will explore the challenges and opportunities faced by preservice teachers and how this experience influences their teaching philosophies and aspirations.Our ultimate goal is to determine how such immersive experiences can contribute to the development of culturally responsive pedagogy. We believe that these preservice teachers, with their enriched perspectives, can become advocates for diversity and inclusion not only within their classrooms but also within the broader educational landscape and society.This research holds the potential to inform teacher education programs and policy discussions regarding the value of cross-cultural experiences in teacher preparation. By shedding light on the impact of volunteer teaching in the Navajo Nation, we hope to contribute to the ongoing dialogue on fostering more inclusive and culturally aware educators, ultimately benefiting students and society as a whole.

Authors: Chance Witt, Devan Hill. Mentors: Jianlong Han, Seth Armstrong, Sarah Duffin. Insitution: Southern Utah University. We study the steady state solutions of a Lotka-Volterra model with crowing effects when delta=2. A nonstandard numerical scheme is proposed, and numerical experiments predict the long term behavior of the numerical solution.

Authors: Webster Madison, Oldroyd Kristina, Shubert Jennifer. Mentors: Shubert Jennifer. Insitution: Utah Valley University. Recent societal events have become benchmarks for understanding how young people interpret and engage with broader social issues. For example, the 2016 election revealed a heightened awareness of systemic racism, inequity, and oppression among youth disapproving of Trump’s presidency, with Latinx groups in particular demonstrating awareness of racism and discrimination across marginalized groups.Furthermore, the Supreme Court’s historic decision to overturn Roe v. Wade ignited nationwide discourse on social issues such as women’s reproductive rights and bodily autonomy, with some interpreting the ruling as perpetuating systemic oppression, a form of cultural imperialism and power imbalance, disproportionately affecting marginalized groups’ access to safe and legal abortions. This study utilizes Young’s (1990) multifaceted oppression framework to investigate how emerging adults demonstrate awareness of oppression in interpreting and responding to societal events.Data came from 104 undergraduate students (Mage= 21.74; 72% Female; 91% White) identifying as conservative, moderate, or liberal. This study collected data from a longitudinal sample through a Qualtrics survey distributed within hours of the Supreme Court decision. Participants responded to open-ended questions regarding their feelings, views, and potential changes in attitudes and behaviors due to the overturn. By applying a coding scheme based on Young’s framework to the narrative responses, evidence of all five dimensions of oppression emerged. Intriguingly, marginalization (i.e., limiting full participation in society) constituted the most prevalent theme, appearing in 52 responses opposing the overturn and 10 supporting the overturn, followed by powerlessness (i.e., inability to make decisions regarding oneself), arising in 40 opposing and 22 supporting narratives. Next, 37 opposing and 33 supporting responses highlighted cultural imperialism (i.e., valuing and enforcing dominant cultural norms). Then, 38 opposing and 8 supporting responses expressed violence (i.e., intentional harm or threat). Finally, only 22 opposing and 8 supporting responses illustrated exploitation (i.e., systemic transfer of resources). These findings suggest that participants across the political spectrum expressed complex reactions to the decision’s ramifications. Evidence of all five facets of oppression in participants’ narratives may shed light on the potential for heightened critical consciousness among individuals navigating the complexities of a post-decision landscape. Further theory building is necessary to understand how young people develop a critical awareness of significant social events and their impact on critical consciousness. Moreover, these findings establish a foundation for advancing critical consciousness theory, particularly concerning period effects and the development of awareness regarding structural privilege, oppression, and inequity.

Authors: Ian Macapagal. Mentors: Joshua Price. Insitution: Southern Utah University. The issue of suicide in the United States constitutes an increasingly concerning economic and public health issue, given the observed rise in suicide rates in recent years and the societal costs incurred by suicides. This paper focuses on the incidence of suicides by firearm, given firearms’ comparatively high usage and lethality in suicides, and investigates the effects of mandatory waiting periods for firearm purchases on the incidence of suicide. Such purchase delays theoretically provide a “cooling off” period, temporarily denying impulsively suicidal individuals the means to commit suicide. This study employs multivariate regression analysis to isolate the effects of having state-level mandatory waiting periods for firearms purchases, as well as the length of such periods, on state-level suicide mortality rates. This analysis is conducted with the aim of investigating the effectiveness of these policies in reducing firearms-related and total suicides, in addition to the extent to which suicidal individuals respond by substituting firearms for other methods.

Authors: Cate Miller, Tyler Free, Brad Bundy. Mentors: Brad Bundy. Insitution: Brigham Young University. Diagnostics are an essential tool in the treatment path for many different types of cancer. They are used to determine the progression of cancer treatment and are critical to increase survival rates. The most common diagnostics are often too expensive or sophisticated to be used on a widespread scale. Using a cell-free protein synthesis system to create a biosensor as a diagnostic can drastically decrease costs, increase convenience, and increase survival rates. We previously engineered low-cost CFPS systems to detect glutamine which would be useful for low-cost biosensing of clinically relevant glutamine concentrations. This work reports our progress in optimizing the CFPS glutamine biosensor for improved performance.

Authors: Riley B. Jackson, Iris Cepeda. Mentors: Michael C Rotter, Kiara Whitley. Insitution: Utah Valley University. Roses (Rosa spp.) are beloved ornamental plants known for their flowers and for their formidable prickles, often referred to as thorns. These prickles are an important part of herbivore resistance in these plants. These mechanical defense structures can vary in shape and abundance and are found along the length of the stems and even the underside of leaves. Although the mere presence of these prickles can cause damage to potential herbivores they also may act as vectors for infectious microbes. Previous studies have shown that other piercing physical defense structures can harbor infectious bacteria, sometimes resulting in conditions such as gangrene, anthrax poisoning, or septic arthritis. This raises the question about their potential implications for human safety particularly when these plants grow in areas of high human use. While roses have similar sharp structures, it is currently unknown if they harbor any pathogenic or defensive bacteria. Our study explores and whether local roses (both native and non-native) have similar or distinct microbiomes and if they possess pathogenic microbes. Understanding these differences would enable us to shed light on ecological relationships between microbes and native versus non-native plants and health risks associated with rose prickle injuries.

Authors: Garrett Johnson, Tyler Free, Brad Bundy. Mentors: Brad Bundy. Insitution: Brigham Young University. Acute Lymphoblastic Leukemia is the most common form of childhood cancer. Asparaginase treatment has greatly improved survival rates to 80%. Survival rates increase by an additional 10% when diagnostic treatment monitoring is used to guide treatment administration. Cell-free protein synthesis is a technology capable of detecting Asparaginase in human serum. However, RNases from human samples destroy CFPS activity. RNase inhibitor can be produced at a low cost by the CFPS system to rescue in-vitro protein synthesis activity to enable biosensing. This work reports our work toward developing an at home Asparaginase diagnostic that would enable personalized dosing of Asparaginase and further improve survival rates of Acute Lymphoblastic Leukemia.

Authors: Joshua Parmley, Acacia Overono. Mentors: Acacia Overono. Insitution: Utah Valley University. Since its founding over a century ago, the American Psychological Association has adopted several distinct roles in its ongoing pursuit of legitimacy, stability, and growth for the field of psychology. Two of its most important roles include the establishment and enforcement of an ethics code and the standardization and development of undergraduate education. These two goals are related; the best way to uphold an ethics code is to ingrain that code into future researchers and practitioners. The APA Guidelines for the Undergraduate Psychology Major 3.0, which lists the APA’s ideal learning objectives for undergraduate programs, attempts to do just that. In its section on ethics training, it places a great degree of responsibility on undergraduate programs to prepare students for a world of bad actors, exploitative systems, and ethical grey areas. To achieve this, the document recognizes that students must develop an ethical skill or proficiency, not just a knowledge of the codes and principles. Unfortunately, Guidelines recommendations for achieving that goal quickly become clouded, as the document wrestles with the various concerns about teaching ethics. Primarily, the Guidelines section on ethics seems conflicted about whether instructors should give students historical examples of psychologists and psychology systems engaging in unethical behavior The Guidelines expresses the concern that presenting students with examples of ethical failures by psychologists will distract students from the learning outcomes or lead them to view the field negatively and abandon it altogether. Accordingly, the APA tentatively recommends that negative examples be shared cautiously, alongside examples of the positive achievements of the field and ethical systems in place. Are the APA’s fears that blunt ethics courses could turn students away from the major valid? Or do the Guidelines recommendations put too little faith in their instructors and students? This study seeks to examine the validity of the APA’s concerns and the efficacy of their recommendations. One hundred and fifty Intro to Psychology students will be divided into three groups. Each group will be instructed in the principles of the APA ethics code using a) no historical examples, b) a balance of negative and positive examples, or c) several negative examples. Participants will then take a survey that measures their ethical proficiency, their memory of the material, and their confidence in the field of psychology. Measurement of ethical proficiency will be adapted from APA measurement tools. We predict that the group instructed with several negative examples, without balancing positive examples, will result in greater measurements of ethical proficiency, better recall, and a slightly lowered level of confidence in the field. We predict this based on the idea that reviewing negative examples in the instructional material will provide students with a specific model of ethical decision-making.

Authors: Matthew Hovorka. Mentors: Connie Ericksen. Insitution: Utah Valley University. This research project examines evidence of individual identity and personhood among perinates, neonates, and young children in the Tiwanaku culture (Western Bolivia, Chile, Peru, A.D. 500-1100) of the ancient Andes. A multifocal approach is taken in examining the topic, and ethnohistorical and archaeological evidence is examined to create a picture of Tiwanaku conceptions of personhood. Through a comprehensive analysis of burial practices, iconography, and ethnohistorical records, this study sheds light on the nuanced conceptions of personhood and individual identity held within the Tiwanaku culture. By delving into the socio-cultural context and material evidence, this research contributes to a deeper appreciation of the complex beliefs and societal values of this ancient Andean civilization.

Authors: Gabriel Hammond, Rebecca Seegraber, Tim Webster. Mentors: Tim Webster. Insitution: University of Utah. Bornean and Sumatran orangutans demonstrate pronounced differences in their social behavior. All orangutans are more solitary than other apes and monkeys, but Bornean orangutans are even less social than their Sumatran counterparts. This contrast is generally attributed to differences in forest productivity between the two islands, as feeding competition is a major cost to social behavior. Variation in sociality between the two species directly impacts male reproductive skew, or the extent to which males can monopolize reproductive success. Sex-biased demographic phenomena such as male reproductive skew can be reconstructed across a lineage’s history by comparing genetic variation across different regions of the genome. Autosomes and the X chromosome are inherited in different proportions, in a population with an equal sex ratio, four autosome copies will be passed down for every three X chromosomes. Deviations in genetic diversity from this expected ratio can be indications of sex biased demographic events. This project is leveraging differential inheritance of chromosomes to explore the role of orangutan socioecology in shaping male reproductive strategies through genomic analysis of reproductive skew across Bornean and Sumatran orangutans.

Authors: Kendra Johnson. Mentors: Dannelle Larsen-Rife. Insitution: Utah Tech University. This study's objective is to examine how sleep quality is related to attachment and any moderating effect from social support. Sleep quality affects multiple aspects of life including physical and mental health. About 40% of the population is affected by sleep complaints (Palagini et al., 2018). Over time, disturbed sleep can become a risk factor for mental illness and substance use disorders (Adams et al., 2014). According to Gur-Yaish et al., (2020), negative interactions related to attachment disturbances negatively affected sleep quality. Individuals with insecure attachment may be more prone to insomnia and sleep disturbances (Palagini et al., 2018). People with anxious attachment have difficulty trusting that others will be there for them when they are in need. Insecure attachment is measured on two scales: anxious and avoidant. Because of this fear, people with insecure attachment may engage in behaviors intended to reassure them of the other person’s trustworthiness. An individual with avoidant attachment tends to resist close relationships, fearing that others are not reliable (Bowlby 1982). Adults in romantic relationships tend to behave similarly to children and mothers when it comes to attachment pairing (Fraley & Shaver, 1998). When people have insecure attachment, they may be highly activated by relationship ruptures, leaving them anxious and vulnerable to poor sleep quality. The resulting poor sleep quality may be moderated by high levels of outside social support, though with high attachment avoidance, the benefits of social support are less influential. Participants (N = 94) completed the Experiences in Close Relationships-Revised (ECR-RS) scale to measure attachment, the Pittsburgh Sleep Quality Index (PSQI), and the Social Support Questionnaire-Short Form (SSQ6). Findings reveal that though the correlation between insecure attachment and sleep was small, the addition of social support revealed some interesting patterns that give insight to the relationship between attachment, sleep, and the effects of social support.

Authors: Ayana Srivastava, Gliceida Galarza Fortuna, Beverly Chigarira, Emre Dal, Chadi Hage Chehade, Georges Gebrael, Arshit Narang, Neeraj Agarwal, Umang Swami, Haoran Li. Mentors: Neeraj Agarwal. Insitution: University of Utah. The utility of ChatGPT in subspecialty consultation for patients (pts) with metastatic genitourinary (GU) cancer.Ayana Srivastava, Gliceida Galarza Fortuna, Beverly Chigarira, Emre Dal, Chadi Hage Chehade, Georges Gebrael, Arshit Narang, Neeraj Agarwal, Umang Swami, Haoran LiHuntsman Cancer Institute at the University of Utah, Salt Lake City, UT;University of Kansas Cancer Center, Westwood, KSBackground:Cancer management requires a multidisciplinary approach, often requiring medical consultation from subspecialists. With the advent of artificial intelligence (AI) technologies like ChatGPT, it is hypothesized that these tools may help expedite the consultation process. This study aimed to assess the efficacy of ChatGPT in providing guideline-based sub-specialty recommendations for managing pts with metastatic GU cancer.Methods:In this single-institution, IRB-approved, retrospective, proof-of-concept study, pts with metastatic GU cancer over the past 3 years were screened. Those with at least one consultation referral to subspecialty clinics were randomly selected. ChatGPT 3.5 was given the most recent clinic note that triggered sub-specialty consultation. The AI tool was then asked to provide an assessment and plan. Two physicians independently assessed the accuracy of diagnoses made by ChatGPT and subspecialty physicians. The primary outcome was the consistency of ChatGPT recommendations with those of subspecialty physicians. Secondary Outcomes included potential time saved by using ChatGPT and comparison of medical decision-making (MDM) complexity levels between ChatGPT and subspecialty physicians.Results:A total of 39 pts were included. Their primary diagnoses included prostate cancer (51.3%), bladder cancer (23.1%) and kidney cancer (15.4%). The referred subspecialty clinic included cardiology (33.3%), hematology (17.9%), hepatology (2.6 %), hospice (10.3%), neurology (12.8%), pulmonary (15.4 %), and rheumatology (7.7%). The average waiting time for pts to be seen in subspecialty clinics was 44.9 days (SD = 42.4). Of 39 patient’s charts reviewed by ChatGPT, 30/39 (76.9%) had the same diagnosis with consultant sub-specialties. The average diagnoses made by ChatGPT were 8.2, compared with 3.4 made by sub-specialty physicians (p < 0.0001). The accuracy of diagnoses made by ChatGPT was the same, higher, and lower than human physicians in 10 (33.3%), 3 (10%), and 17 (56.7%) cases, respectively. Consistency of treatment plans between ChatGPT and physicians was found in 18 cases (46.2%). ChatGPT recommended additional workup in 32 cases (85.1%). The average number of words written in consultation notes by ChatGPT was 362.7 (SD = 72.9), which was significantly greater than subspecialty physicians (n = 224.7, p < 0.0001).Conclusions:These hypothesis-generating data suggest the potential utility of ChatGPT to assist medical oncologists in managing increasingly complex pts with metastatic cancer. Further studies are needed to validate our findings.

Authors: Hunter Mitchell, Grace Carsey, Maria Balaceanu, Peg Bird, Bridger Lisonbee, Dannelle Larsen-Rife. Mentors: John Jones. Insitution: Utah Tech University. Early experiences in the home have long-term effects on health and well-being. This study will examine the connections between parenting styles and coping mechanisms, shedding light on their implications for child development and adult mental health and well-being. Parenting styles looked at in this study, specifically authoritarian has varied views on expectations, discipline, and rewards (Doepke & Zilibotti, 2017). Parenting styles have been shown to impact how children express themselves, and more specifically their expression of anger (Radomir-Beliţoiu, 2019). The expression of anger may indicate a deficiency in healthy coping skills. When individuals are found without healthy ways of coping, they become increasingly vulnerable to mental health disorders and poor relationship satisfaction. Based on our current understanding we believe that an authoritarian parenting style will be positively correlated with unhealthy coping mechanisms such as avoidance, substance use, and self-criticism. Adult participants (N = 100) varying in ethnicity and age will be recruited to complete the Brief Cope Questionnaire (Carver, 1997) and an adaptive version of the Parenting Styles and Dimensions Questionnaire (PSDQ; Robinson, Mandleco, Olsen, & Hart, 2001) to assess their parent's style of parenting and their ability to cope with challenges. We will run an ANOVA on the collected data using SPSS. We expect to see a correlation between parenting styles and children’s coping skills. It is anticipated that there will be a strong positive correlation in unhealthy coping skills and parental strategies. This study may suggest the importance of educating children and young adults in healthier coping skills and adults in healthy parenting strategies. This education may aid in reducing the frequency and intensity of mental health crisis in adults.

Authors: Patrick R Davies II. Mentors: Acacia Overono. Insitution: Utah Valley University. While there is a dedicated area of the brain for recognizing faces, the efficacy of recognition tasks can vary depending on the context under which they’re performed. The existing literature is undecided on whether anxiety helps or harms tasks relating to emotional content recognition, and some studies have taken steps into researching memory as an additional layer to these recognition tasks. A preliminary study was performed with 16 participants using virtual reality to study the effects of acute anxiety on the ability to correctly identify faces. Participants played either a brief horror game or a brief virtual sandbox in order to induce a desired emotional state, then were asked to complete a brief paired-face identification paradigm. Initial results show that anxiety strengthens identification of neutral emotionally-valent face pairs. Further results may clarify the relationship between anxiety and face identification processes.

Authors: Sophia Dodge. Mentors: Alex Greenwald. Insitution: University of Utah. This project seeks to address the understudied presence of Gambel Oak acorns in the archaeological record of the Great Basin, Colorado Plateau, and Southwest regions. While ethnographic data and historical records suggest that Native peoples in this area consumed some Gambel Oak acorns, their recognition in archaeological contexts has been limited. This study aims to assess the viability of methodologies for identifying macrobotanical acorn remains, shedding light on their utilization across different time scales, especially as fallback crops during resource shortages, such as climate shifts. Through experimental methods like burning, parching, and midden simulation we will determine how these methods impact the identifiability of acorns. The research holds significance for our understanding of past human responses to climate change and the ongoing struggle for Indigenous food sovereignty, providing valuable insights into sustainable food sources for the future.

Authors: Jared Barrot, Mackenzie Burr, Isaac Packer, Peyton Worley, Delaney Anderson, Jack Davis, Jeffrey Okojie, Ken Dixon. Mentors: Jared Barrott. Insitution: Brigham Young University. In cancer diagnosis, drug testing, and treatment, analysis is done almost exclusively on formalin-fixed paraffin-embedded (FFPE) tissue samples, a process known to cause chemical cross-linking, DNA fragmentation, and degradation. With the push for genetic testing and personalized medicine, cryopreservation of tissue samples has started to gain traction in the research community. We utilized FFPE samples and cryopreserved samples, extracted DNA, and compared the samples using three criteria: DNA purity, quality, and yield. DNA yield, measured on nanograms of DNA to milligrams of tissue basis, demonstrated a five times the yield in cryopreserved samples than in FFPE. DNA purity did not show significant differences between a cryopreserved tissue sample versus a FFPE tissue sample, confirming valid use of FFPE storage methods if purity is the only factor; however, DNA quality was significantly better in cryopreserved tissue samples, with nearly twice the DNA quality number (DQN) than FFPE samples demonstrated, with significant portions of longer base pair DNA fragments present, widening the range of molecular applications of the sample. These cryopreserved tissues provide higher DNA quality, a higher percentage of significantly longer DNA fragments, and increased DNA yield from individual samples, confirming that cryopreservation is a better option than FFPE when it comes to choosing tissue preservation and storage methods. More molecular assays and tests can be run, and smaller samples are necessary when utilizing cryopreservation, proving it to be a better option than the “gold standard” of FFPE, particularly in regards to cancer diagnosis, drug testing, and treatment exploration.

Authors: Peg Bird, Maria Balaceanu, Grace Carsey, Tiffanee Suhaka, Hunter Mitchell, Ives Hong, Tara Caplin, Ed Wu, John T Jones, Dannelle Larsen-Rife. Mentors: John T Jones. Insitution: Utah Tech University. This study examines the relationship between perfectionism and self-compassion. Perfectionism may be beneficial, but often promotes unrealistically high self-imposed standards, a preoccupation with making mistakes, and a compulsivity toward order, leading to self-criticism and self-loathing. Perfectionism results in persistent feelings of failure, indecision, procrastination, and shame, which negatively impact relationships, work-life satisfaction, and overall well-being (Enns et al., 2001; Frost et al., 1993). Self-compassion is directing warmth and care toward oneself during times of suffering and comprises three core components: self-kindness (offering oneself warmth during adversity), common humanity (acknowledging shared suffering), and mindfulness (approaching the experience of pain with presence and curiosity) (Neff, 2003). Self-compassion is associated with mental health and well-being, including a stable sense of self-worth, increased resilience, life satisfaction, and perspective-taking. Furthermore, self-compassion negatively correlates with anxiety and depression, reduced fear of failure, perfectionism, and self-criticism (Barnard et al., 2011; Neff, 2003; Neff et al., 2006). This correlational study will recruit approximately 100 adult participants to evaluate associations between perfectionism and self-compassion. Participants will complete the Frost Multidimensional Perfectionism Scale and the Self-Compassion Scale (Frost et al., 1990; Neff, 2003). We anticipate a negative correlation between self-compassion and perfectionism, with higher levels of self-compassion corresponding with lower levels of perfectionism. If this prediction is supported by the data, the study’s outcomes will extend existing research on the potentially deleterious effects of perfectionism and pave the way for the development of interventions aimed at improving mental health outcomes among individuals adversely impacted by this trait.

Authors: Natalia Rubio, Madison Farrer. Mentors: Christopher Anderson. Insitution: Utah Valley University. Functional Near-Infrared Spectroscopy (fNIRS) is a neuroimaging technique used to monitor brain activity by measuring the changes in blood oxygenation levels, especially when presented with stimuli or given tasks. This is due to the principle that active brain regions require more oxygen, resulting in changes of blood flow and concentrations of hemoglobin. These observable results are achieved by diodes placed on the surface of the scalp that emit near-infrared (NIR) light into the skull. The absorption of this light by the hemoglobin in the brain’s blood vessels is then detected, localizing neural activity. Due to its portability and cost-efficient nature, fNIRS is being widely used across various fields of research and clinical applications whereas other neuroimaging methods might be less feasible or practical. Psychologists and neuroscientists are able to utilize fNIRS to understand how different regions of the brain are involved in various cognitive processes. It has been used in studying conditions like Alzheimer's disease, stroke, traumatic brain injury, autism, schizophrenia, mood disorders, and dementia. In the context of dementia research, fNIRS has emerged as a promising tool . While fNIRS has a low spatial resolution with measurements restricted to the outer cortex of the brain, it enables the study of the progression of dementia by providing real-time data and offering relative tolerance to subject motion. In fact, a neuro-clinic in Provo, Utah (Cognitive FX) has been studying the use of this fNIRS technique on patients with dementia while they perform language tasks. Although no patient data will be used in this study, the use of fNIRS as a technique to learn about the progression of dementia is noteworthy. Therefore, following IRB approval I will perform semi-structured qualitative interviews with two neuro-technicians using fNIRS in this clinic. Items will focus on the strengths and challenges of using fNIRS with dementia patients. Additionally, I will shadow these technicians to gain hands-on experience. Qualitative results will be analyzed and presented. It is anticipated that this research project will raise awareness of the use of fNIRS as a technique in neuroscience as well as its potential to benefit those with dementia.

Authors: Ana Paulina Medellin-Alvarez, Jared Almazan, Tursun Turapov, David A. Kircher, Karly A. Stanley, Gennie L. Parkman, MiKaela N. Field, Katie M. Culver, Silvia Coma, Jonathan A. Pachter, Howard Colman, Sheri L. Holmen. Mentors: Sheri Holmen. Insitution: University of Utah. Despite promising results from recent FDA-approved therapies, many advanced melanoma patients develop resistance to both immunotherapy and targeted therapy. A common resistance mechanism to targeted therapy is upregulation of the PI3K/AKT signaling pathway, which has also been shown to promote the development of melanoma brain metastases. Historically, AKT inhibitors have failed in the clinic due to their limited efficacy or intolerable toxicity. Proteomic analysis comparing non-metastatic vs brain metastatic primary tumors in mice revealed focal adhesion kinase (FAK) as an AKT1 specific effector and a potential alternative therapeutic target. FAK is a non-receptor tyrosine kinase that localizes primarily to focal adhesions to regulate cell migration. To determine whether targeting FAK alone or in combination with the RAF/MEK inhibitor avutometinib reduces brain metastases and prolongs survival, we utilized both autochthonous and syngeneic melanoma mouse models. Mice with either subcutaneous tumors or established brain metastases were treated with FAK inhibitor, RAF/MEK inhibitor, or the combination of FAK and RAF/MEK inhibitors. Each cohort was assessed for tumor onset, growth, metastasis, and survival. Our results show that combined RAF/MEK/FAK inhibition significantly delays tumor onset, causes regression of established tumors, prevents the development of brain metastases, promotes the regression of established brain metastases, and prolongs survival. In addition, patient-derived BRAF V600E melanoma xenograft mouse models resistant to the BRAF inhibitor dabrafenib and the MEK inhibitor trametinib, were sensitive to combined RAF/MEK/FAK blockade. The addition of the BRAF inhibitor encorafenib to these models further enhanced the effect on tumor growth. These results support the initiation of a clinical trial evaluating the efficacy of the RAF/MEK inhibitor avutometinib in combination with the FAK inhibitor defactinib in patients with brain metastases from cutaneous melanoma. Additionally, we are assessing non-canonical roles of FAK in modulating the tumor microenvironment to determine whether avutometinib and defactinib also enhance the efficacy of immune checkpoint inhibition in this disease.

Authors: Corin Marsh, Acacia Overono. Mentors: Acacia Overono. Insitution: Utah Valley University. A variety of memorization techniques have been shown to enhance the ability to recall important information. While many of these techniques focus on repetition and retrieval of verbal information, the drawing superiority effect (DSE, Wammes et al., 2016) is a phenomenon where drawing leads to better recall compared to re-writing. The present study investigates the extent of these findings by combining the DSE with retrieval practice. This experiment utilized a within-subjects, single-blind design consisting of 32 undergraduate students ranging in age from 18 to 42. Participants were tasked with learning 20 vocabulary terms through a guided slideshow, then studied terms through; reading definitions (verbal restudy), viewing images of the definitions (visual restudy), writing definitions (verbal retrieval), and drawing definitions from memory (DSE with retrieval). After a brief distractor task, participants were tested on their recall of the definitions. Finally, subjects completed a shortened version of the Vividness of Visual Imagery Questionnaire (VVIQ) and a funnel debrief. Preliminary analyses using a repeated measures ANOVA revealed that re-reading was the study method that resulted in the highest recall scores (M = .57) compared to all other conditions (F (3, 93) = 14.9, p < .001, ηp2 = .324). Further — VVIQ ability showed no significant correlation with participant scores for any of the study methods. These results indicate that re-reading was a more effective study strategy for memorizing vocabulary terms with a short delay when compared to viewing images, writing definitions, and drawing definitions from memory. Future work will examine how longer delays and providing feedback influence may modulate the benefits of re-reading, drawing, and retrieval as study strategies. Keywords: drawing superiority effect, retrieval practice, memory, VVIQ

Authors: Broden Lund, John Jones. Mentors: John Jones. Insitution: Utah Tech University. Pursuing higher education credentials involves a significant investment of money, time, and energy. For many, this investment fails to pay off when students abandon their studies prior to graduation. Identifying factors that influence persistence to graduation has thus been the subject of a good deal of past research. The aim of this ongoing study is to explore the interaction between motivation type, responses to failure, and self-efficacy, on persistence among students at different stages of their academic careers. Participants will be 100 college students currently enrolled at a mid-sized university in the United States. Participants will complete measures of academic motivation, coping strategies in response to failure, and self-efficacy. We predict that the further a student progresses the more intrinsically motivated they will tend to be, and that this shift in motivation will be accompanied by increasing reliance on problem-focused coping and increased self-efficacy. Our results have the potential to provide a more nuanced understanding of the role intrinsic motivation plays in student success. Implications for students, parents, teachers, and administrators will also be considered.

Authors: Jacob Prescott. Mentors: Zoe Thompson. Insitution: Utah Valley University. The pro-opiomelanocortin (Pomc) gene encodes POMC, which is differentially processed to produce adrenocorticotropic hormone (ACTH), beta-endorphin, and three melanocyte-stimulating hormones, among other peptides. POMC neurons are principally located in the arcuate nucleus (Arc) of the hypothalamus, where they are essential in the control of food intake, energy expenditure and body weight. Several different mutations in the POMC gene have been shown to cause early-onset obesity and adrenal cortical insufficiency in humans. We are working with a mouse model with a hypothalamic-specific POMC deficiency. These mice exhibit hyperphagia, early-onset obesity, and also seem to be infertile. We are interested in examining potential differences in pubertal development, as well as reproductive function. Specifically, we will examine day of vaginal opening, day of first estrus, and estrus cycling in juvenile female POMC-deficient mice. The estrus cycle has four stages: proestrus, estrus, metestrus and diestrus. Although hormone levels in the blood differ during the four stages, these are difficult and expensive to measure. A less invasive measurement is to take vaginal cell samples each day and examine them under the microscope. Three different types of cells are present in different ratios depending on the stage of the cycle: nucleated epithelial cells, leukocytes, and cornified epithelial cells. We will track estrus cycle changes during pubertal development and after to see if there are differences between wildtype, heterozygous, and homozygous POMC-deficient mice.Learning more about how POMC-deficiency affects reproductive function may help us understand more about the link between obesity and infertility.

Authors: Cora Rasmuson, Carly Biedul, David Herbst. Mentors: Carly Biedul. Insitution: Westminster College. Great Salt Lake (GSL) is a unique ecosystem known for its elevated saline conditions, supporting diverse biological communities. However, GSL's vital habitats for birds and invertebrates are diminishing due to climate variability and water diversions. The keystone species, Ephydra gracilis, known as brine flies, is central to this ecosystem's food web.Microbialite mounds of haloarchaea, algae, and cyanobacteria sustain E. gracilis, but receding shorelines and record-low lake levels intensify salinity, reducing food sources and brine fly survivability. This decline has far-reaching consequences, as E. gracilis accounts for over 50% of the diet for 10 million migratory birds at GSL.Ongoing research is focused on refining methods for monitoring populations of Ephydra species in response to changing salinity and elevation levels. This research is vital for the preservation of the lake's ecosystem and biodiversity.

Authors: Michaela Thackeray, Cicilee Petersen, Scott Wiltbank, Emma Newman, Enoch Thackeray. Mentors: Matt Draper. Insitution: Utah Valley University. Abstract: Unlocking Well-Being, Workplace Morale, and Employee Retention: A Tech Company’s Success Story This qualitative study, titled "Unlocking Well-Being, Workplace Morale, and Employee Retention: A Tech Company’s Success Story," explores the experiences of employees and leaders at a Utah-based tech company with an unusually low turnover rate. Motivated by the National Institute of Mental Health's call for workplace well-being focus and exacerbated mental health issues during the COVID-19 pandemic, this research investigates the factors contributing to the company's low turnover and high employee satisfaction. The study employs a series of case studies to delve deeply into individual experiences, utilizing phenomenological methods to uncover and describe the depth and breadth of participants' experiences. The research question guiding the study is, “What experiences inform the mental health and well-being of employees and leaders at this low-turnover company individually and collectively?” Qualitative data collection involved interviews with executives, managers, and employees, facilitated through Microsoft Teams software or on-site at the company campus. The data was transcribed, blocked, and analyzed using Giorgi’s Phenomenological Method, a descriptive qualitative approach, supplemented by Nvivo 12 Plus or similar software for a broader thematic examination across participants. The study aims to provide insights into the workplace dynamics that contribute to employee well-being, satisfaction, and retention in the context of a successful tech company. We will present our findings by poster presentation and are open to presenting orally. Thank you for your consideration!

Authors: Heidi Kipp, Annika Jones, . T. Heath Ogden. Mentors: T. Heath Ogden. Insitution: Utah Valley University. The purpose of this research is to identify and document mayfly instars from a parthenogenetic population of individuals being raised in the lab. Instars are the developmental stages of an arthropod between molts. Mayflies (and other non holometabolous insects) go through incomplete metamorphosis, moving from egg to nymph stages, and then to subimago (unique to mayflies), and imago (or adult). Previous research indicates the number of instars to be between 12-45 depending on the species, and the species we studied is estimated to have around 15. During each instar, mayflies shed their exoskeleton. The difference between each instar is vital to understanding the changes in gene expression and overall life cycle of a species. Instars have subtle differences, and identifying them will help further research into which genes are involved in producing specific morphological characteristics. Defining these structures, such as the forming of eyes or wings, are of particular interest in evolutionary phylogenetics. We raised Centroptilum trianguilfer (Ephemeroptera: Baetidae) in a controlled water tank, collecting and dating egg samples from mature imagos. Water is maintained with standard ion composition with 130-400 conductivity. Once the eggs hatched, we performed daily inspections and measurements using a 40x stereomicroscope microscope and Lumenera Infinity Analyze. We are using basic appearance, size and morphology) to separate instars. We will identify and photograph each instar. Samples from the different instars, subimagos, and adults will be acquired and used to generate transcriptome data. We propose that our research will aid in the investigation of mayfly evolution and their genetic mechanisms of control.

Authors: Akir Rowe, Hali Hutchinson, Kingdom Wanjoku. Mentors: Katrina Twing. Insitution: Weber State University. Polychlorinated biphenyls (PCBs) are toxic chemicals popularly used in electrical manufacturing companies from the 1930s - 1970s. PCBs, colloquially known as ‘forever chemicals’, are known to cause significant health concerns and are notoriously difficult to remove from an environment. PCBs are currently banned in the US; however, they can still be found in the environment due to improper disposal methods. This research aims to better understand ecological networks, genomic novelties, and potential bioremediation of microbes from PCB-contaminated environments. Microcosm cultures were developed to resemble the original conditions of the environmental samples, containing PCB-contaminated mud from Woods Pond, Lenox, Massachusetts, and filtered pond water with three different treatments: aerobic, anaerobic, and anaerobic with the addition of sulfate. These cultures have been growing for five months, showing signs of active microbial metabolism (e.g., rust patches in sediment gas production). The microcosms were used as inoculum for agar containing PCBs, and 30 PCB-tolerant colonies were isolated, with some belonging to known PCB-degrading taxa of Paenibacillus, Clostridium, Rhizobium, Methylversatalis, and Sphingobacteria. Future analyses will be conducted to (a) identify the microbial diversity within the microcosms via 16S rRNA amplicon sequencing, (b) explore the metabolisms within the microcosms, and (c) further characterize the isolated PCB-tolerant bacteria. This data will aid further research to determine if and how these microbes metabolize PCB compounds.

Authors: Jerzee Findlay, Gina Fuller. Mentors: Katrina Twing. Insitution: Weber State University. Polychlorinated Biphenyls (PCBs) are toxic chemicals which were popularly used in electrical manufacturing companies from the 1930s - 1970s and are known to cause significant health concerns for humans even today. These have also been termed “forever chemicals” due to their ability to bind to sediments and soils, which results in difficulties with removal or degradation in contaminated environments. One site of widespread PCB contamination is Pittsfield, Massachusetts, where improper disposal of industrial waste by a General Electric plant has led to chronically contaminated rivers and ponds, even decades later. The aim of this research project is to learn more about the microbial communities that coexist with these toxic forever chemicals, hoping to find evidence that they can degrade PCBs through metabolism. This specific study within the project focuses on microbial diversity of sediment samples collected from the contaminated Woods Pond, located downstream of the Pittsfield General Electric plant.: We performed DNA extractions, PCR amplification, and 16S rRNA amplicon sequencing on an Oxford Nanopore MinION DNA Sequencer. Preliminary data suggest that the samples contain genera known to be associated with PCB degradation, such as Paenibacillus, Clostridium, Rhizobium, and Sphingobacteria. With this understanding, future efforts aim to evaluate the ability of these environmental bacteria to degrade PCBs.

Authors: Logan Walker, Kate Coneys, Nick Tops, Russ Bailey. Mentors: Russ Bailey. Insitution: Utah Valley University. Background: Cultural humility is an influential concept in Multicultural Orientation therapeutic research (Owen et al, 2011). Cultural humility is defined as “a lifelong process of self-reflection and self-critique whereby the individual comes to value and respect cultural diversity, recognizes his or her own biases, and is open to learning from others" (Tervalon & Murray-Garcia, 1998, p. 117). Cultural humility practices attempt to address cultural differences in therapy. Therapy absent of cultural humility can run the risk of failing the needs of culturally diverse clients. Racial and ethnic minorities are more likely to experience premature termination (Owen et al., 2015). Premature termination is defined as when a client begins an intervention but discontinues prior to recovering from the problem that he or she sought treatment for against provider recommendations (Swift & Greenberg, 2012). Premature termination is a significant concern as those who do not complete an intervention are less likely to experience symptom relief or meet their treatment goals (Steinberg et al., 2019). hope to better understand the link between cultural humility and premature termination/treatment deterioration in therapy in college students. We hypothesize that lower therapist’s cultural humility will be associated with an increased likelihood to unilaterally terminate therapy prematurely or show treatment deterioration. Methods: Data was collected from students who participated in therapy at the Utah Valley University Student Health Services from 2021-2023. The sample size for this dataset is approximately 560 participants. We will use two different operationalizations of premature termination/treatment deterioration: 1. Clients who reported have attended therapy for at least 3 sessions, has at least 1 cultural humility datapoint, and reported feeling “worse than at intake” on an item of subjective progress during at the last attended session with no future sessions scheduled for at least 90 days. 2. Clients who scored worse or the same on well-being indictors (PHQ-9 and GAD-7) and reported feeling “the same as intake” or “worse as intake” on an item of subjective progress during the last attended session with no future sessions scheduled for at least 90 days.. Clients completed the Cultural Humility Scale (Hook, 2013) and microaggression items at the beginning of their 3rd session and then every 4 sessions (e.g., session 7, 11, etc.). Clients completed the PHQ-9, GAD-7, and subjective progress items at the beginning of every session. We will use logistic regression to see how cultural humility scores and microaggression frequency/impact predict premature termination/treatment deterioration. Results: Results from the analyses will be presented during the poster presentation Discussion: The results of the study will help us determine if therapist's cultural humility is related to client premature termination. If we find support for our hypothesis, this means that cultural humility is an important factor in therapeutic processes that has direct impact on the effectiveness for therapy interventions. However, rejecting our hypothesis may suggest that cultural humility is not an important aspect of premature termination. Limitations of this study include potential ceiling effects due to therapists striving to be cultural humble and thus limiting the variability in our sample.

Authors: Ellery White. Mentors: Yi Yin. Insitution: Utah Valley University. This study will examine the influence that parental political beliefs may have on students’ academic performance. Decades of research have formed empirical links between social- contextual factors and student academic achievement, and this paper will seek to identify whether parental political values play a role in the academic achievement of their children (Lee and Shute 2010; Yamamoto and Holloway 2010). Parental attitudes, behavior, and stylistic approaches to their child’s rearing and education have been extensively studied for how they impact educational outcomes (Pandey and Thapa 2017). This study fulfills the gap in research on the association between parental political beliefs and children’s academic performance. This adds to the academic discourse on the impact parents can have on their children in an academic setting by answering the following questions: How can the political beliefs of parents impact a students’ way of thinking and therefore ability to perform in school? Does the extremity of the parents’ political beliefs make a difference in the outcome of the child’s academic performance? A survey was distributed to a random sample of UVU students which measured their academic performance and the political beliefs of their parents. The statistical program SPSS will be used to conduct a multiple regression analysis to examine the relationship between the independent variable (parents’ political beliefs) and dependent variable (students’ academic performance) to see if there is an association between the two. I hypothesize that students with parents who have strong political beliefs are more likely to be impacted in their academic performance than students with parents who do not have strong political beliefs. Discovering the impact of parental political belief will open several important avenues of inquiry related to educational outcomes of students.

Authors: Melissa Rangel, Avery Larsen, Heath Ogden. Mentors: Heath Ogden. Insitution: Utah Valley University. Mayflies, also known as ephemeroptera, are members of the first group of insects that evolved the ability to fly(Gillott, 2005). Distinct developmental characteristics of the life stages of the mayfly are the reason that Ephemeroptera are of particular interest.The aquatic nymph stages do not have wings, but they do possess abdominal leaf-shaped gills, and in some cases gills associated to the legs. The abdominal gills can sometimes be used to help propel the insect through its environment (Eastham, 1936) in addition to performing gas exchange. Centroptilum triangulifer (family Baetidae), will be used for RNA extractions to study the developmental genetic profiles for characteristics such as wings and gills. Objectives for this research are 1). Acquire samples from different instars, subimago, and imago. 2) Perform 10 RNA extractions. 3) Use Qubit technology to ensure ≥ 20 ng/μL RNA concentration per ≥ 10 μL. 4) samples will be packaged in thermo-stable shipping boxes and sent to Novogene where samples are tested once more for quality control. 5) Once quality is confirmed, samples will be sent and processed by Novogene. 6). Using an in-house bioinformatics workflow, RNA data will be checked for quality, trimmed, aligned, and assembled. The assembled contains will be used to search for genes of interest. 7) the resulting RNA expression profiles will be compared across the installs, sub imago, and imago and to other expression profiles from other related insects.

Authors: Stephen Chamberland, Craig D. Thulin, Katherine Solorzano, Cassandra Beddes, Nathan Twitchell, Abram Caruso. Mentors: Steve Chamberland, Craig D. Thulin. Insitution: Utah Valley University. This investigative procedure is a continuation of an experiment done by UVU undergraduate student Kyra Banks and her mentor, UVU Professor of Chemistry Craig Thulin, to determine the structure of xanthommatin. Xanthommatin is one of the primary pigments found in monarch butterflies, and many other insects. Data obtained during the mass spectrometric analysis was observed to indicate a possible deamination of xanthommatin, however the quantity of deaminated xanthommatin observed was too small and so the structure could not be determined. The research investigates the precedented deamination of kynurenine as a model to develop a procedure for the deamination of 3-hydroxykynurenine, primarily due to the fact that it is cheaper in price to xanthommatin, as well as a chemical precursor that can be used for the synthesis of xanthommatin. The implications of this suggest that the deamination procedure developed for 3-hydroxykynurenine could be successfully replicated with xanthommatin. After the deamination procedure has been successfully repeated, xanthommatin will be synthesized using one of a few procedures developed by Kumar, A., et al1. Once a sufficient sample of xanthommatin has been successfully synthesized, the deamination procedure will be repeated on samples of xanthommatin to determine the structure of deaminated xanthommatin using NMR spectroscopy. The research conducted here is beneficial not only because it is a continuation of other UVU student’s and staff’s work, but also to those whose work is in the animal biology realm of science. The information that will be extracted from this research will spearhead new research pathways and questions to be explored.Xanthommatin-Based Electrochromic Displays Inspired by Nature (acs.org)Biomimetic Colorants and Coatings Designed with Cephalopod-Inspired Nanocomposites (acs.org)

Authors: Karissa Bauer, Kennedy Lewis, James Belnap, Andrew Torena, Braden Freestone, Luis Montenegro Calla. Mentors: Daniel Clark. Insitution: Weber State University. In the United States, 157 documented cases of primary amoebic meningoencephalitis (PAM) have been recorded between 1962 and 2022. In the 60 years since the first reported case, only four patients have survived; a 97.5% fatality rate. The causative agent responsible for the highly fatal infections, is the free-living, single-celled parasite, Naegleria fowleri— or the “brain-eating amoeba.” The aquatic thermophiles are opportunistic pathogens that inhabit a wide range of environments; from poorly maintained pools, moist sediment, rivers, lakes, etc. Exposure to N. fowleri invasion is reliant on direct contact with a host’s upper nasal mucosa, and the active parasite. Rapid deterioration of neural tissues occurs shortly after infection.Today, there is no universally accepted treatment plan for treating PAM infections. The CDC has recommended an empirical approach to treatment, and suggests utilizing combination drug-therapies. Suggested drugs include Amphotericin B, Azithromycin, Fluconazole, Miltefosine, and Rifampin. To better understand and evaluate the effects of these drugs on N. fowleri, a rescue-of-infection model was applied to test the efficacy of single and combination-drug treatments, at various time points. The model utilized an immortalized HeLa cell line that was infected with the amoebae until roughly 50% cytotoxicity was observed. The rescue stage commenced with drug additions, and HeLa cell metabolism, and apoptosis levels were monitored using fluorescence viability assays and caspase-3 enzyme detection systems. Drug combinations that included Rifampin and Amphotericin B, provided the greatest protection for human Hela cells against N. fowleri infections. Data collected from this model provides deeper understanding of Naegleria fowleri pathogenicity. This knowledge will aid the development of more reliable and efficient treatments for this devastating infection.

Authors: Genna Howard, Cameron John. Mentors: Cameron John. Insitution: Utah Valley University. In the history of psychology, the concept of soul played a significant role informing philosophy and theory. In the late 1800’s many questioned the concept of soul in favor of measurable concepts that aligned with the scientific method, distinguished from religious classification that were deemed unworthy of pursuit. In the emergence of the science method, the concept of soul faded and the field of psychology experienced soul-loss, becoming soul-less. After nearly 150 years, there is a movement in the field advocating for soul to return to its former status by shedding light back onto the soul. For some, soul is aligned with religious thought. Religions are experiencing a loss of congregants, members engaging in faith transitions, and experiencing soul-loss. This paper will compare and contrast what happened in psychology with the experiences of some in religious organizations while looking at how the emotion of fear plays a part in both organizations. The methodology utilizes historical concepts and experiences shared by the brave souls who are challenging the current beliefs in both fields. In addition, anecdotal, informal information provided by individuals close to the authors is used to emphasize the practical application of this crisis in psychology and religions with the goal of reigniting a passion for soul.

Authors: Kate Coneys, Nick Top, Russ Bailey, Logan Walker, Julia Toomey. Mentors: Russ Bailey. Insitution: Utah Valley University. Background: Past literature has emphasized the importance of practicing culturally competent care and has shown that higher clinician cultural humility, as well as a lower frequency of microaggressions occurring in therapy, have been associated with more desirable therapeutic outcomes in retrospective, cross-sectional studies. However, research has also shown that patient outcomes appear to be unrelated to their therapist's experience level (Erekson et al., 2017), suggesting that more experience may not lead to being a more effective therapist, including more culturally humble. Despite the breadth of research on the significance of cultural competence, less is known about how a therapist's cultural humility changes across treatment with a particular client, or how a therapist’s cultural humility changes over an extended period. The aim of the current study is to examine this concept by analyzing both the relationship between the number of sessions spent working with a given therapist and a client’s rating of the clinician’s cultural humility, as well as the relationship between the average cultural humility rating of the therapist and time. We will also examine how the impact of microaggressions occurring in therapy changes during the course of therapy. Hypotheses: It is hypothesized that the results of this study will show a positive association between the number of sessions with the same therapist and their cultural humility, as rated by the client, as well as a negative association between the number of sessions and the impact of microaggressions reported by the client. Additionally, it is hypothesized that the therapist’s cultural humility rating over the entire course of data collection will not change to a statistically significant degree. Methods: We used archival data collected by Utah Valley University’s Student Health Services Counseling Center from August 2021 – September 2023. This archival dataset consists of 564 clients with at least one cultural humility and microaggression data point. Beginning at the third session, and occurring again every four sessions, clients were asked to rate their clinician’s cultural humility, using The Cultural Humility Scale (Hook et al., 2013), and report the frequency and impact of microaggressions that had occurred during the last four sessions. We will analyze the data using multi-level latent growth modelling. Results: Results will be presented as part of the poster presentation. Discussion: If the results of this study agree with the hypothesis, the implications may be that cultural humility improves over time with specific clients, potentially explained by growth of therapeutic alliance over time. However, it may also imply that a therapist’s cultural humility does not improve over extended time periods, showing that cultural humility appears to be static rather than dynamic. If the results do not agree with the hypothesis, this may imply that a client’s perception of their therapist’s cultural humility is static, but that over extended periods of time a therapist’s cultural humility can improve, implying that it is trainable. Sources: Erekson, D.M., Janis, R., Bailey, R.J., Cattani, K., Pedersen, T.R. (2017). A longitudinal investigation of the impact of psychotherapist training: Does training improve client outcomes? Journal of Counseling Psychology, 64(5), 514-524. https://doi.org/10.1037/cou0000252 Hook, J.N., Davis, D.E., Owen, J., Worthington, E.L., Utsey, S.O. (2013). Cultural humility: measuring openness to culturally diverse clients. Journal of Counseling Psychology, 60(3), 353-366. https://doi.org/10.1037/a0032595

Authors: Lindsay Beekman. Mentors: Olga Kopp. Insitution: Utah Valley University. This research probes the primary historical newspapers of early 1900s Utah, providing insights into the cultural atmosphere of the time and the widespread support for the Eugenics movement throughout the state. Our findings indicate that out of 72 distinct newspaper articles discussing Eugenics in Utah between 1908 and 1938, 62 conveyed a positive perspective, 9 remained neutral, and only 1 expressed opposition. Notably, from 1947 to 1996, leaders of The Church of Jesus Christ of Latter-Day Saints administered the ‘Indian Student Placement Program’ or ‘Lamanite Placement Program,’ aligning with many Eugenics principles. Utah, like many places worldwide, embraced Eugenics with open arms.

Authors: Lauren Silvatti.. Mentors: Zoe Thompson. Insitution: Utah Valley University. Proopiomelanocortin (Pomc) deficiency, stemming from a mutation in the Pomc gene, presents a myriad of health challenges, including extreme hyperphagia, early-onset obesity, and infertility. This study leverages a mouse model exhibiting Pomc-deficiency to delve into the root causes of infertility. While the correlation between obesity and fertility is well-established, our primary focus is to discern whether the POMC mutation independently contributes to reproductive challenges. Our investigation extends into the interplay of genetics, endocrinology, and obesity through data analysis using R, with an emphasis on deploying advanced statistical models.Video recordings of sexual behavior interactions have been analyzed manually, with independent observers marking each behavior. The frequency and duration of each behavior will be compared among three groups of pairings: wildtype-wildtype, heterozygote-heterozygote, and homozygous POMC-deficient mice. Techniques will include data cleaning, timestamp manipulation, and behavior categorization in R, a programming language commonly used for data analysis. To discern patterns and variations, our analysis will also employ statistical models such as linear mixed-effects models. We can account for potential confounding variables and significant differences in durations of previously identified important reproductive behaviors. Visualization tools, including box plots and violin plots, will provide an initial glimpse into the distribution of behavior durations. Subsequently, we plan to conduct inferential statistics, employing techniques such as Analysis of Variance (ANOVA) to assess the significance of differences across multiple groups. Our investigation extends beyond descriptive statistics, with a focus on predictive modeling. Regression analyses will explore potential relationships between behavior durations and reproductive success. Machine learning algorithms will be applied to uncover complex interactions within the dataset.The anticipated results promise not only a nuanced understanding of the interplay between Pomc mutations and reproductive challenges but also the identification of potential biomarkers or predictors of successful reproduction. This comprehensive statistical approach contributes significantly to the fields of genetics, endocrinology, and obesity research, offering a robust framework for future investigations into the intricate relationship between genotype and behavior.

Authors: Heidi Blaylock, Carter Leuba, Eddie Hill, Christina Aguilar, Carla Cox, Aiden Hill. Mentors: Eddie Hill. Insitution: Weber State University. Type 1 diabetes (T1D) is a chronic disease that influences all health aspects. The self-determination theory (SDT) suggests that three psychological needs of competence, autonomy, and relatedness are necessary for motivation to engage in healthy behaviors. Through medical specialty camps, these needs can be met by educating campers on how to manage T1D and realize they are not alone. The volunteer-based, five-day, inaugural REACH teen/tween camp for youth with T1D was held at WSU. Camp activities were engineered around the three basic needs described by the SDT. These needs were promoted by physical and educational activities, and meeting friends. A pre and post evaluation was given. Two measures were significant with autonomy being the greatest, (M=3.93, SD= .75) to post test (M=4.49, SD= .56), with t(25) = -6.258, p= <.001), effect size r = 1.2 Blood glucose levels were collected through an online platform that allowed staff to monitor campers’ levels. The week's average blood glucose level was 152 mg/dL. This study explored the use of SDT to examine the effectiveness of a diabetes camp for youth and hopefully result in better physical and emotional health thus mitigating the risk of complications.

Authors: Brandon Rojas. Mentors: Kristen Arnold. Insitution: Weber State University. The Mountain Haven building in Salt Lake City, a mixed-use facility, offers a wide range of services, including housing, childcare, and healthcare. The Single Parent Project, a non-profit organization, is working to provide suitable housing solutions for single parents and their children. The primary challenge is creating a secure, private, and healthy living environment that supports the emotional, financial, and mental growth of single parents and their children. To address this challenge, the Mountain Haven building must be designed to meet the unique needs of single-parent families. This includes providing access to quality childcare, flexible work arrangements, and efficient household management solutions. It is also important to foster a sense of community and neighborliness and to ensure that single parents have access to affordable and safe housing in a safe neighborhood (Johnson, 1986). Additionally, the arrangement of the home should be flexible to accommodate both work and childcare responsibilities. The design of the Mountain Haven building should also consider the latest research on daycare centers, healthcare facilities, and interior design. This includes using materials that are free of harmful substances, creating spaces that promote learning and nurture children's development (Monoko, Mukurunge, Bhila, 2021), and using light and color to create a healing environment for parents and children to reduce stress and strengthen the mood, mind, and body. (Khaleghimoghaddam, 2023) By incorporating these principles into its design, the Mountain Haven building can provide single parents and their children with a safe, supportive, and nurturing environment in which to thrive.

Authors: Kennedy Parker. Mentors: Melinda Russell Stamp. Insitution: Weber State University. Role-playing is considered one of the most effective teaching strategies for training undergraduate clinical psychology students because it fosters active learning in a supportive and safe environment (Gibbs, 2019; Osborn & Costas, 2013). The literature is replete with studies that document the benefits of role-playing for clinical training. These benefits include the development of active-listening, perspective-taking, empathy, critical thinking, communication, collaboration, problem-solving, and increased enjoyment of course material (Dawood, 2013; Gibbs, 2019; Grose-Fifer, 2017). A challenge associated with classroom role-plays involves student reluctance to participate due to feelings of self-consciousness and anxiety associated with being negatively evaluated (Mallonee, 2018). There is limited research on the effectiveness of different role-play modalities which may include classmates role-playing with one another; as well as actors and virtual avatars role-playing with students. There have been mixed findings in the literature regarding whether students are more comfortable disclosing to virtual avatars or to actors in face-to-face encounters (Rogers et al., 2022; Roster & Chen, 2016). To date, there are no research studies comparing student perceptions of role-plays with virtual avatars to face-to-face interactions with actors in undergraduate psychology classes. For the current study, 60 undergraduate Psychology students were randomly assigned to either role-play with an avatar or an actor. Following the 25-minute role-plays, students completed surveys assessing perceived utility value, self-efficacy, level of anxiety, engagement, and future interest in role-playing. This preliminary study will compare the effectiveness of avatar and actor role-play modalities which will help educators better structure training for undergraduate students in clinical psychology.

Authors: Tara Caplin, Tiffanee Suhaka, Maria Balaceanu, Peg Bird, Dannelle Larsen-Rife. Mentors: Dannelle Larsen-Rife. Insitution: Utah Tech University. Early parent-child interactions have a profound impact on the developing brain, influencing lifelong emotional and social well-being. This review evaluates the Newborn Behavioral Observation (NBO), a relationship-based neurobehavioral approach for families and infants three months old and younger. The NBO supports newborns, caregiver’s, and families by providing individualized information on their infants' behavior and competencies. It facilitates communication and intersubjectivity between infants and caregivers during a critical developmental period, while reducing maternal postpartum depression (PPD). Research on the association between the NBO, PPD, and infant neurodevelopment is reviewed and evaluated in high-risk populations. Although evidence supports approaches like the NBO, they are not yet standard in early intervention due to clinicians' lack of training in infant mental health. The NBO is a foundational tool for cultivating positive early relationships with beneficial implications for clinician standard care of newborns and families. Keywords: Newborn Behavioral Observation (NBO), early relationships, postpartum depression (PPD), infant development, relationship-based, early intervention.

Authors: Maria Balaceanu, Dannelle Larsen-Rife, Tara Caplin, Peg Bird, Grace Carsey, Tiffanee Suhaka. Mentors: Dannelle Larsen-Rife. Insitution: Utah Tech University. Attachment theory provides a framework for understanding how early experiences with caregivers influence individuals' emotional and relational development throughout their lives. In addition to understanding how an individual interacts with close others, attachment predicts relationship satisfaction (Gardner et al., 2020). Individuals with secure attachments demonstrate greater adaptability in coping and regulating their emotions, leading to improved socio-emotional well-being. In contrast, those with insecure attachment styles tend to encounter difficulties in socio-emotional adjustment (Gardner et al., 2020). This study will examine how insecure attachment is associated with romantic relationship dissatisfaction, specifically those lasting five years or longer. We focus exclusively on romantic relationships lasting five years or more because in adult relationships, each partner serves as an attachment figure for the other (Diamond et al., 2008). Therefore, spouses have the potential to increase each other's attachment security. This means an initially insecure individual can develop earned secure attachment with their spouse's support. Approximately 300 diverse participants over the age of 18 will be recruited for the study. The Relationship Structures Questionnaire (ECR-RS; Fraley et al., 2011) will assess insecure attachment. The Relationship Assessment Scale (Hendrick, 1988) will assess satisfaction. It is expected insecure attachment will be correlated with lower relationship satisfaction with a romantic partner of five years or longer. Results of the analyses will be presented.

Authors: Mary Harris. Mentors: Joshua Gubler. Insitution: Brigham Young University. Middle Eastern governments typically score at or near the bottom of indices measuring women’s rights and political participation. The Middle East also contains a large saturation of authoritarian regimes. The Arab Spring challenged these regimes' structures and included vast female participation, but there is little existing research to understand the Spring's impact on women's participation and empowerment in the region. This study aims to add to the research by gathering data from the Arab Barometer to plot public opinion surveys before, during, and after the Arab Spring for a variety of countries in the Middle East and North Africa region. A difference on difference t-test shows the statistical difference of change in opinion before and during the Arab Spring. Twenty semi-structured interviews (conducted in Jordan in 2022) supplemented the quantitative analysis attempting to show the causation between the Arab Spring and the growth in public opinion toward women's empowerment. These are conducted under the hypothesis that: Women’s participation in the Arab Spring improved public opinion towards women’s empowerment in the region. The quantitative analysis illustrates a correlation between the Arab Spring and opinions of women's empowerment, but the shifts of opinions are both negative and positive. The data suggests that the negative impact is connected with the second half of the Arab Spring when the governments were subject to more instability. The interview's results differ from the hypothesis and illustrate little connection between the Arab Spring and public opinion of women's empowerment. These results are affected by the lack of movement in Jordan during the Arab Spring. More research is needed to understand the causation of such a phenomenon in other countries.

Authors: Danielle Alvarado, Kasidy Weber, Shannon Buckley. Mentors: Shannon Buckley. Insitution: University of Utah. The ubiquitin-proteasome system (UPS) plays a critical role in cancer by regulating the degradation of key proteins involved in cell cycle control, DNA repair, apoptosis, and signaling pathways, making it a crucial mechanism for maintaining cellular homeostasis and preventingtumor development and progression. The expression levels of F-box ubiquitin E3 ligase, FBXO21, correlates with patient survival in several types of cancer, suggesting a role in tumorgenesis. We have previously shown silencing FBXO21 in acute myeloid leukemia (AML) cell lines and patient samples leads to differentiation, slowed tumor progression, increased chemotherapy sensitivity, and altered cytokine signaling. Further, we found that FBXO21 ubiquitinates p85α, a regulatory part of the phosphoinositide 3-kinase (PI3K) pathway, for degradation resulting in altered PI3K signaling. Although PI3K inhibitors are used in cancertreatment, issues like off-target effects, dose-limiting toxicities, and resistance necessitate further research and development for optimized efficiency and minimal negative effects in targeting the PI3K pathway. To further understand the role of FBXO21 in cancer, we utilized shRNAs targeting FBXO21 in various cancer cell lines to identify the role of FBXO21 in cellular proliferation, apoptosis, and alteration of the PI3K pathway. The PI3K signaling pathway is initiated through p85α binding to the catalytic subunit, p110, leading to downstream AKT and mTOR activation. We found knockdown of FBXO21 stabilizes p85α, leading to dimerization of free p85 and decreased PI3K pathway activation. Therefore, we hypothesize that FBXO21 may function as a novel regulator of PI3K signaling, offering an alternative approach to PI3K inhibitors. Our findings suggest that FBXO21 may represent a novel therapeutic target acrossvarious cancer subtypes to target the overactive PI3K pathway. Targeting FBXO21 may enhance the efficacy of current therapies and provide potential benefits for improving patient outcomes in the treatment of cancer, including but not limited to AML

Authors: Jude Werth. Mentors: Alex Shcheglovitov. Insitution: University of Utah. Glioblastoma (GBM) is the deadliest brain tumor that affects more than 10,000 people a year. Unfortunately, our understanding of the mechanisms disrupted by GBM is extremely limited. We are unable to safely manipulate brain cells in live patients, and the complexity of human brain networks are difficult to recapitulate in animals. This study employs brain organoids, derived from induced Pluripotent Stem Cells (iPSCs), to model the impact of GBM on neural activity. Organoid batches, grown under normal conditions and co-cultured with GBM cells, were monitored using microelectrode arrays (MEA) to record power in frequency bands. Over time, drugs influencing neural activity were introduced. Significant behavioral distinctions were observed between control and GBM-cultured organoids. Under Bicuculline and Tetrodotoxin, power in GBM organoids exhibited dramatic changes compared to the minimal difference in control organoids. Conversely, 4-Aminopyridine induced increased high-frequency activity exclusively in control organoids. Correlating power in frequency bands with spike activity, this study provides insight on how brain tumors influence neural networks, furthering disease comprehension to eventually develop effective treatment for patients.

Authors: Trenton M. Gibson, Brett E Pickett. Mentors: Brett E Pickett. Insitution: Brigham Young University. Lynch Syndrome, formerly known as Hereditary Non-Polyposis Colorectal Cancer, is an autosomal dominant condition characterized by non-functional DNA mismatch repair genes, leading to mismatch repair deficiency (dMMR). Individuals with dMMR have an increased risk of developing cancerous tumors with microsatellite instability (MSI). The aim of this study was to investigate significant perturbations in gene expression among different dMMR variants within Lynch Syndrome, specifically focusing on variants in the PMS2, MLH1, and MSH2 loci. We obtained 55 public RNA-seq human colorectal tumor samples with specific germline dMMR mutations and 20 samples of healthy colorectal epithelium from the GENE Expression Omnibus (GEO). These samples were subjected to a robust RNA-seq data preprocessing and analytical workflow, which involved quality control, trimming, read pseudomapping and quantification using Salmon, identification of significant differentially expressed genes using edgeR, and gene ontology enrichment analysis using Camera. Signaling pathway impact analysis (SPIA) was employed to assess gene pathway perturbations. Our results revealed that tumor samples from individuals with germline mutations in the PMS2 MMR gene exhibited transcriptomic profiles indicating upregulation in pathways related to intrinsic and extrinsic prothrombin activation, fibrinolysis, and uPA/uPAR-mediated signaling, in comparison to other tumor and healthy samples. Previous research has established a correlation between these pathways and tumor growth, invasiveness, and metastasis. These findings provide a foundation for further research to explore the interactions between PMS2 and these pathways in influencing tumor development.

Authors: Bryce Tolman, Jasper Terungwa Iorkula , Justin Singleton, Matt Peterson. Mentors: Matt Peterson. Insitution: Brigham Young University. An efficient method for preparing C-3 aminated pyrazolo[1,5-a]pyrimidines was developed. The method consisted of treating 3-bromopyrazolo[1,5-a]pyrimidine with a wide range of 1° or 2° alkylamines with CuI (20 mol%), L-proline (40 mol%), and Et 3 N (2 equiv) in DMSO under microwave heating conditions (130 °C, 4 hours). C-3 aminated products were obtained in good to excellent isolated yields (54–90%; ave. yield = 77%), and represents the most broadly applicable, non-palladium-catalyzed amination of 3-bromopyrazolo[1,5-a]pyrimidine ever reported. The coupling worked well for unfunctionalized 1° alkylamines such as butylamine, benzylamine, isopropylamine or cyclohexylamine, and more densely functionalized 1° amines with CH 2 - or CH 2 CH 2 -linked heterocycles were also well tolerated (e.g. pyridine-, indole-, thiophene-, and furan-linked methyl- or ethylamine derivatives). 2° Alkylamines such as morpholine, pyrrolidine, and piperidine also reacted well under these conditions. Heating under conventional oil-bath conditions required a more extended reaction time (40 h), but also gave products in good yield (72-76%) for both 100-mg and gram-scale reactions. A pegylated azide (11-azido-3,6,9-trioxaundecan-1-amine) was also coupled in good yield (65% yield microwave), demonstrating compatibility of this methodology for potential click-type applications. Our method is simple and efficient, and avoids drawbacks associated with alternative methods, including long reaction times, limited substrate scope, and required use of air-sensitive/extremely expensive palladium catalysts and specialized synthetic ligands.