Cancer Research
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Improved transgenic mouse models recapitulate aggressive human osteosarcoma
Author(s): Peyton Worley, Alma Taggart
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Alterations in Colorectal Cancer Gene Expression among Metformin Users and Non-Users
Author(s): Emma Richardson
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For Longer Than I Have Known You: An Artistic Documentation of Loss Due to Cancer
Author(s): Hazel Harris
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Epigenetic Reprogramming in Pediatric Tumors Predicts Active Pathways in the Tumor Microenvironment
Author(s): Noah Moffat, Clark Tolbert, Colin Wessman
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Immune mediators of the FLASH effect in melanoma
Author(s): Joshua Knight, Allison Stevens, Madison Hawkins, Alec Morimoto, Ben Shaver, Taylor Steins, Danielle Johnson-Erickson
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A different dimension: a comparison between 2D cell lines and 3D organoids in cancer drug screening cell viability
Author(s): Isaac Packer, Jeffery Okojie, Delany Anderson, Victoria Johnson, Paytin Curran
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Prostate Cancer Incidence Rates, Trends, and Treatment Related to Prostate-Specific Antigen Screening Recommendations in the United States
Author(s): Daniel Guerrero Gutierrez, Jade Viveiros
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Investigating the Role of FBXO3 in Malignant Hematopoiesis
Author(s): Joshua Hutchins
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Deciphering Synergy: Pterostilbene and Dabrafenib in Melanoma Treatment
Authors: Reno Blackmore, Jacob Mead, Wyatt Legas, Jennifer Meyer. Mentors: Jennifer Meyer. Insitution: Utah Tech University. Introduction: Our research is dedicated to unraveling the mechanisms that drive the efficacy of anti-cancer drugs, with a specific focus on melanoma cases characterized by the BRAF mutation.Objective: Our primary objective is twofold: firstly, to establish a synergy index between pterostilbene and dabrafenib, unearthing their collaborative potential; secondly, to delve deep into the mechanisms using protein characterization and gene expression. This exploration not only has the potential to enable the use of lower drug concentrations for achieving the desired reduction in melanoma cell viability but also offers the prospect of reducing patient stress, as pterostilbene is a naturally occurring plant compound.Preliminary data from our study already suggests a promising synergistic relationship between pterostilbene and dabrafenib, which underscores the significance of further investigation into their combined therapeutic potential.
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Logic-gated LINK CAR to increase specificity of chimeric antigen receptor (CAR) T cells in autoimmune disease
Author(s): Chloe Kang, Abigail Cheever, Hunter Lindsay, Kimball Demars
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Impact of interobserver variability on breast cancer segmentation and MRgFUS simulations
Author(s): Jacob Lehnhof, Taylor Forbes, Nicole Peterson, Rachel Harris, Ben Jackson, Jacob Moulder, Drew Wagstaff, Amelia Benedict, Brianne Geiger, Estee Revill
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Synthesis of gold nanorods as payloads for antibody drug conjugates for synovial sarcoma
Author(s): Melanie I'anson-Holton, Andralyn McKell, Jeffrey Okojie, Bridger Kearns, Josh Hanosek
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Indirect Regulation of MCL1 Protein by NF-κB Signaling in Acute Lymphoblastic Leukemia Cells
Author(s): Christian Barker
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The Use of Fluorescent Dyes for Detecting the Biodistribution of C. Novyi-NT
Author(s): Caleb Hoffman, Jackson Sandberg
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Social Support Among Cancer Survivors in Malawi: A Mixed Methods Study
Author(s): Nehal Bakshi, Abhilasha Khatri
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