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Utah Conference on Undergraduate Research
Utah's Foremost Platform for Undergraduate Research Presentation

Cancer Research

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2025 Abstracts

Deciphering Synergy: Pterostilbene and Dabrafenib in Melanoma Treatment

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Authors: Reno Blackmore, Jacob Mead, Wyatt Legas, Jennifer Meyer. Mentors: Jennifer Meyer. Insitution: Utah Tech University. Introduction: Our research is dedicated to unraveling the mechanisms that drive the efficacy of anti-cancer drugs, with a specific focus on melanoma cases characterized by the BRAF mutation.Objective: Our primary objective is twofold: firstly, to establish a synergy index between pterostilbene and dabrafenib, unearthing their collaborative potential; secondly, to delve deep into the mechanisms using protein characterization and gene expression. This exploration not only has the potential to enable the use of lower drug concentrations for achieving the desired reduction in melanoma cell viability but also offers the prospect of reducing patient stress, as pterostilbene is a naturally occurring plant compound.Preliminary data from our study already suggests a promising synergistic relationship between pterostilbene and dabrafenib, which underscores the significance of further investigation into their combined therapeutic potential.
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2025 Abstracts

Cryopreserved vs. FFPE Cancer Tissue in Before and After Metrics of Whole Genome Sequencing

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Author(s): DeLaney Anderson
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2025 Abstracts

Photochromic Solutions to Skin Cancer

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Author(s): Kylee Jamison, Taron Thang, Michael Orr
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2025 Abstracts

Social Support Among Cancer Survivors in Malawi: A Mixed Methods Study

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Author(s): Nehal Bakshi, Abhilasha Khatri
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2025 Abstracts

Prostate Cancer Incidence Rates, Trends, and Treatment Related to Prostate-Specific Antigen Screening Recommendations in the United States

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Author(s): Daniel Guerrero Gutierrez, Jade Viveiros
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2025 Abstracts

The Use of Fluorescent Dyes for Detecting the Biodistribution of C. Novyi-NT

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Author(s): Caleb Hoffman, Jackson Sandberg
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2025 Abstracts

Targeting VPS34: A Structural Approach to Drug Design Using X-ray Crystallography

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Author(s): Mikaela Burtch, Reuben Dass, Celeste Litchfield, Jamison Cartwright
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2025 Abstracts

Effect of Radiotherapy Volume on Outcomes After Neoadjuvant Radiation for Pancreatic Cancer

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Author(s): Amanda Carlson
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2025 Abstracts

Indirect Regulation of MCL1 Protein by NF-κB Signaling in Acute Lymphoblastic Leukemia Cells

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Author(s): Christian Barker
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2025 Abstracts

SGK1 may represent a therapeutic target in BRAF-mutant melanoma

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Author(s): Boyd Griffiths, Spencer Carter, Camden VanTassell, Katie Culver, Tursun Turapov, Ashley Thompson
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2025 Abstracts

Role of PTEN Lipid and Protein Phosphatase Activity in Melanoma Invasion and Metastasis

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Author(s): Savannah Pettey
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2025 Abstracts

COVID-19 Pandemic Effect on Cancer Incidence Rates

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Author(s): Ian Gibbons
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2025 Abstracts

Investigating the role of FAK on melanoma migration and invasion

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Author(s): Kasidy Estheimer, Karsyn Cannon, A. Paulina Medelin
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2025 Abstracts

Impacts of Riluzole on inhibitory interneurons in the context of ionizing radiation: a spatial transcriptomic analysis

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Author(s): Baylee Christensen, Karli Babcock, Tyle Sorenson, Dalton Scott, Kenyon Mantle, Zach Ferguson
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2025 Abstracts

Alterations in Colorectal Cancer Gene Expression among Metformin Users and Non-Users

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Author(s): Emma Richardson
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2025 Abstracts

Epigenetic Reprogramming in Pediatric Tumors Predicts Active Pathways in the Tumor Microenvironment

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Author(s): Noah Moffat, Clark Tolbert, Colin Wessman
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2025 Abstracts

Innovating Patient Compliance to Improve Cancer Detection: An Undergraduate Study on the Impact of a Mobile App for Enhanced Colonoscopy Preparation

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Author(s): Jackson Hardy
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2025 Abstracts

Microrheological Assessment of Skin Reconstructs: Implications for Melanoma and Extracellular Matrix Studies

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Author(s): Kyler Turner
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