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2025 Abstracts

Deciphering Synergy: Pterostilbene and Dabrafenib in Melanoma Treatment

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Authors: Reno Blackmore, Jacob Mead, Wyatt Legas, Jennifer Meyer. Mentors: Jennifer Meyer. Insitution: Utah Tech University. Introduction: Our research is dedicated to unraveling the mechanisms that drive the efficacy of anti-cancer drugs, with a specific focus on melanoma cases characterized by the BRAF mutation.Objective: Our primary objective is twofold: firstly, to establish a synergy index between pterostilbene and dabrafenib, unearthing their collaborative potential; secondly, to delve deep into the mechanisms using protein characterization and gene expression. This exploration not only has the potential to enable the use of lower drug concentrations for achieving the desired reduction in melanoma cell viability but also offers the prospect of reducing patient stress, as pterostilbene is a naturally occurring plant compound.Preliminary data from our study already suggests a promising synergistic relationship between pterostilbene and dabrafenib, which underscores the significance of further investigation into their combined therapeutic potential.
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2025 Abstracts

Cryopreserved vs. FFPE Cancer Tissue in Before and After Metrics of Whole Genome Sequencing

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Author(s): DeLaney Anderson
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2025 Abstracts

Social Support Among Cancer Survivors in Malawi: A Mixed Methods Study

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Author(s): Nehal Bakshi, Abhilasha Khatri
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2025 Abstracts

Development of new SphK1-inhibiting PROTACs to increase susceptibility of cancer cells to treatment

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Author(s): Michael Kezele
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2025 Abstracts

Novel Cancer Treatment: Enhancing Tumor Suppression In Drosophila Melanogaster

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Author(s): Peyton Jackson
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2025 Abstracts

Fibrosis in the aging ovary driven by pregnancy history and genotype, and potential considerations in ovarian cancer risk.

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Author(s): Giulia Tintorri
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2025 Abstracts

Photochromic Solutions to Skin Cancer

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Author(s): Kylee Jamison, Taron Thang, Michael Orr
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2025 Abstracts

Effect of Radiotherapy Volume on Outcomes After Neoadjuvant Radiation for Pancreatic Cancer

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Author(s): Amanda Carlson
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2025 Abstracts

Impact of interobserver variability on breast cancer segmentation and MRgFUS simulations

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Author(s): Jacob Lehnhof, Taylor Forbes, Nicole Peterson, Rachel Harris, Ben Jackson, Jacob Moulder, Drew Wagstaff, Amelia Benedict, Brianne Geiger, Estee Revill
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2025 Abstracts

Logic-gated LINK CAR to increase specificity of chimeric antigen receptor (CAR) T cells in autoimmune disease

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Author(s): Chloe Kang, Abigail Cheever, Hunter Lindsay, Kimball Demars
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2025 Abstracts

Impacts of Riluzole on inhibitory interneurons in the context of ionizing radiation: a spatial transcriptomic analysis

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Author(s): Baylee Christensen, Karli Babcock, Tyle Sorenson, Dalton Scott, Kenyon Mantle, Zach Ferguson
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2025 Abstracts

Prostate Cancer Incidence Rates, Trends, and Treatment Related to Prostate-Specific Antigen Screening Recommendations in the United States

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Author(s): Daniel Guerrero Gutierrez, Jade Viveiros
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2025 Abstracts

Investigating the role of FAK on melanoma migration and invasion

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Author(s): Kasidy Estheimer, Karsyn Cannon, A. Paulina Medelin
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2025 Abstracts

Microrheological Assessment of Skin Reconstructs: Implications for Melanoma and Extracellular Matrix Studies

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Author(s): Kyler Turner
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2025 Abstracts

The Use of Fluorescent Dyes for Detecting the Biodistribution of C. Novyi-NT

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Author(s): Caleb Hoffman, Jackson Sandberg
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2025 Abstracts

COVID-19 Pandemic Effect on Cancer Incidence Rates

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Author(s): Ian Gibbons
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2025 Abstracts

Targeting VPS34: A Structural Approach to Drug Design Using X-ray Crystallography

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Author(s): Mikaela Burtch, Reuben Dass, Celeste Litchfield, Jamison Cartwright
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2025 Abstracts

Synthesis of gold nanorods as payloads for antibody drug conjugates for synovial sarcoma

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Author(s): Melanie I'anson-Holton, Andralyn McKell, Jeffrey Okojie, Bridger Kearns, Josh Hanosek
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